PT1242055E - Forma de dosagem de fármaco baseada em hidrogel - Google Patents

Forma de dosagem de fármaco baseada em hidrogel Download PDF

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Publication number
PT1242055E
PT1242055E PT00983435T PT00983435T PT1242055E PT 1242055 E PT1242055 E PT 1242055E PT 00983435 T PT00983435 T PT 00983435T PT 00983435 T PT00983435 T PT 00983435T PT 1242055 E PT1242055 E PT 1242055E
Authority
PT
Portugal
Prior art keywords
hydrogel
dosage form
drug dosage
driven drug
driven
Prior art date
Application number
PT00983435T
Other languages
English (en)
Inventor
William John Curatolo
Leah Elizabeth Appel
Dwayne Thomas Friesen
Ronald Arthur Beyerinck
Mark Brian Chidlaw
Kelly Lincoln Smith
Avinash Govind Thombre
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of PT1242055E publication Critical patent/PT1242055E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
PT00983435T 1999-12-23 2000-12-20 Forma de dosagem de fármaco baseada em hidrogel PT1242055E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17196899P 1999-12-23 1999-12-23

Publications (1)

Publication Number Publication Date
PT1242055E true PT1242055E (pt) 2008-07-02

Family

ID=22625827

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00983435T PT1242055E (pt) 1999-12-23 2000-12-20 Forma de dosagem de fármaco baseada em hidrogel

Country Status (42)

Country Link
US (3) US20020015731A1 (pt)
EP (2) EP1242055B1 (pt)
JP (1) JP4100910B2 (pt)
KR (1) KR100523127B1 (pt)
CN (1) CN1402632A (pt)
AP (1) AP2002002553A0 (pt)
AR (1) AR027091A1 (pt)
AT (1) ATE392890T1 (pt)
AU (1) AU783685B2 (pt)
BG (1) BG106865A (pt)
BR (1) BR0016708A (pt)
CA (1) CA2395333C (pt)
CR (1) CR6656A (pt)
CZ (1) CZ20022046A3 (pt)
DE (1) DE60038698T2 (pt)
DK (1) DK1242055T3 (pt)
DZ (1) DZ3228A1 (pt)
EA (1) EA004370B1 (pt)
EE (1) EE200200361A (pt)
ES (1) ES2302705T3 (pt)
GE (1) GEP20043334B (pt)
GT (1) GT200000222A (pt)
HU (1) HUP0301242A3 (pt)
IL (1) IL149224A0 (pt)
IS (1) IS6340A (pt)
MA (1) MA26859A1 (pt)
MX (1) MXPA02006328A (pt)
NO (1) NO20022970L (pt)
NZ (1) NZ518281A (pt)
OA (1) OA12128A (pt)
PA (1) PA8509001A1 (pt)
PE (1) PE20010985A1 (pt)
PL (1) PL357535A1 (pt)
PT (1) PT1242055E (pt)
SI (1) SI1242055T1 (pt)
SK (1) SK8572002A3 (pt)
SV (1) SV2002000250A (pt)
TN (1) TNSN00253A1 (pt)
TR (1) TR200201646T2 (pt)
WO (1) WO2001047500A1 (pt)
YU (1) YU35302A (pt)
ZA (1) ZA200204960B (pt)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR028253A1 (es) 2000-03-16 2003-04-30 Pfizer Prod Inc Inhibidores de la glucogeno fosforilasa
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US7678387B2 (en) * 2000-06-06 2010-03-16 Capricorn Pharma, Inc. Drug delivery systems
US20100196466A1 (en) * 2000-06-06 2010-08-05 Capricorn Pharma Inc. Drug delivery system
US20070059367A1 (en) * 2000-06-06 2007-03-15 Cherukuri S R Drug Delivery System and Associated Methods
US7115279B2 (en) * 2000-08-03 2006-10-03 Curatolo William J Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors
JP2004534811A (ja) * 2001-06-22 2004-11-18 ファイザー・プロダクツ・インク ポリマーと薬剤の集合体を含む医薬組成物
EP1406630A1 (en) 2001-07-06 2004-04-14 Endo Pharmaceuticals Inc. Parenteral administration of 6-hydroxy-oxymorphone for use as an analgesic
MXPA04007438A (es) 2002-02-01 2004-10-11 Pfizer Prod Inc Composiciones farmaceuticas de dispersiones amorfas de farmacos y materiales que forman microfases lipofilas.
JP2005522424A (ja) * 2002-02-01 2005-07-28 ファイザー・プロダクツ・インク コレステリルエステル転移タンパク質インヒビターの制御放出性薬剤投与形態
AU2003269744A1 (en) * 2002-05-15 2003-12-02 Sun Pharmaceutical Industries Limited Oral osmotic controlled drug delivery system
US20040076668A1 (en) * 2002-07-03 2004-04-22 Pfizer Inc. Controlled-release pharmaceutical formulations
WO2004050068A1 (en) 2002-11-29 2004-06-17 Janssen Pharmaceutica N.V. Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base
EA011579B1 (ru) * 2003-02-07 2009-04-28 Актавис Груп Хф Композиция с пролонгированным высвобождением венлафаксина
WO2004098572A1 (en) * 2003-05-06 2004-11-18 Ranbaxy Laboratories Limited Biphasic release of glipizide from monocompartment osmotic dosage form
MXPA06001417A (es) 2003-08-04 2006-05-15 Pfizer Prod Inc Composiciones farmaceuticas de adsorbatos de farmacos amorfos y materiales que forman microfases lipofilas.
US8025899B2 (en) * 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US8377952B2 (en) * 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
WO2005020929A2 (en) * 2003-09-02 2005-03-10 Imran Ahmed Sustained release dosage forms of ziprasidone
US8715724B2 (en) * 2004-10-29 2014-05-06 Mayne Pharma International Pty Ltd Tabletting process
WO2006072878A1 (en) * 2005-01-07 2006-07-13 Ranbaxy Laboratories Limited Oral dosage forms of sertraline having controlled particle size and processes for their preparation
GB0504547D0 (en) * 2005-03-04 2005-04-13 Delsol Products Ltd Personal lubricant
CN101146521A (zh) * 2005-03-14 2008-03-19 太阳医药高级研究有限公司 提供包含纤维素和甲基丙烯酸衍生物包衣的口服药物输送系统
US20080242642A1 (en) 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US7541347B2 (en) 2007-04-02 2009-06-02 Medicis Pharmaceutical Coropration Minocycline oral dosage forms for the treatment of acne
US8252776B2 (en) 2007-04-02 2012-08-28 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US8722650B1 (en) 2005-06-24 2014-05-13 Medicis Pharmaceutical Corporation Extended-release minocycline dosage forms
US7919483B2 (en) * 2005-06-24 2011-04-05 Medicis Pharmaceutical Corporation Method for the treatment of acne
US7544373B2 (en) * 2007-04-02 2009-06-09 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US20080241235A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
WO2007057762A2 (en) * 2005-11-16 2007-05-24 Pfizer Limited Osmotic bi-layer tablet
US20080241197A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline dosage forms for the treatment of acne
CN101439026B (zh) * 2007-11-23 2011-04-06 北京红林制药有限公司 含有多沙唑嗪或其盐的控释制剂及其制备方法
MX2010008861A (es) * 2008-02-15 2011-02-22 Sun Pharma Advanced Res Co Ltd Tableta oral de liberacion controlada con efecto de liberacion masiva reducido.
WO2010017310A1 (en) 2008-08-06 2010-02-11 Medicis Pharmaceutical Corporation Method for the treatment of acne and certain dosage forms thereof
KR101004205B1 (ko) 2008-12-17 2010-12-24 동아제약주식회사 유데나필 함유 서방성 제제를 제조하기 위한 제어방출 조성물
KR101284368B1 (ko) 2010-07-09 2013-07-15 서울대학교산학협력단 나노섬유시트 기재의 경구용 약물의 제어 전달을 위한 시스템
US9532952B2 (en) 2011-01-28 2017-01-03 Physician's Seal, LLC Controlled-release compositions of melatonin combined with sedative and/or analgesic ingredients
US8691275B2 (en) * 2011-01-28 2014-04-08 Zx Pharma, Llc Controlled-release melatonin compositions and related methods
US9561241B1 (en) 2011-06-28 2017-02-07 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for minocycline
ES2725879T3 (es) * 2013-01-30 2019-09-30 Daewoong Co Ltd Composición farmacéutica para la protección de heridas, para proporcionar una hemostasia o para evitar la adhesión en el tracto gastrointestinal
EP2968180B1 (en) * 2013-03-14 2019-04-24 Amgen Inc. Heterocyclic compounds and their uses
CA2902646C (en) 2013-03-14 2022-08-16 Cytokinetics, Inc. Heterocyclic compounds and their uses
US20170182070A1 (en) 2014-10-08 2017-06-29 Mayne Pharma International Pty Ltd. Controlled Release Doxycycline
AR106018A1 (es) 2015-08-26 2017-12-06 Achillion Pharmaceuticals Inc Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
WO2017035408A1 (en) 2015-08-26 2017-03-02 Achillion Pharmaceuticals, Inc. Compounds for treatment of immune and inflammatory disorders
AU2017290593A1 (en) 2016-06-27 2019-01-03 Achillion Pharmaceuticals, Inc. Quinazoline and indole compounds to treat medical disorders
US20230022157A1 (en) 2018-08-20 2023-01-26 Achillion Pharmaceuticals, Inc. Pharmaceutical compounds for the treatment of complement factor d medical disorders
EP3866773A4 (en) 2018-10-16 2022-10-26 Georgia State University Research Foundation, Inc. CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL CONDITIONS
US20230248654A1 (en) * 2020-07-10 2023-08-10 Adare Pharmaceuticals, Inc. Swellable oral pharmaceutical compositions
BR112023004824A2 (pt) 2020-09-18 2023-04-18 Bristol Myers Squibb Co Formas de dosagem para inibidores tyk2 compreendendo núcleos intumescíveis
WO2023063381A1 (ja) * 2021-10-14 2023-04-20 静岡県公立大学法人 粉末製剤
WO2023154171A1 (en) * 2022-02-14 2023-08-17 Purdue Research Foundation Polymer salts for improved drug delivery from amorphous solid dispersions

Family Cites Families (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4111202A (en) * 1976-11-22 1978-09-05 Alza Corporation Osmotic system for the controlled and delivery of agent over time
US4327725A (en) * 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
US5366738A (en) * 1982-07-29 1994-11-22 Merck & Co., Inc. Controlled release drug dispersion delivery device
IT1165797B (it) * 1982-10-18 1987-04-29 Consiglio Nazionale Ricerche Procedimento di preparazione di alchilangelicine esenti da psoraleni ed alchilangolicine ottenute col procedimento
US4612008A (en) 1983-05-11 1986-09-16 Alza Corporation Osmotic device with dual thermodynamic activity
US4783337A (en) * 1983-05-11 1988-11-08 Alza Corporation Osmotic system comprising plurality of members for dispensing drug
US4765989A (en) * 1983-05-11 1988-08-23 Alza Corporation Osmotic device for administering certain drugs
US5082668A (en) * 1983-05-11 1992-01-21 Alza Corporation Controlled-release system with constant pushing source
GB8322007D0 (en) * 1983-08-16 1983-09-21 Wellcome Found Pharmaceutical delivery system
US4624848A (en) 1984-05-10 1986-11-25 Ciba-Geigy Corporation Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use
US4968507A (en) * 1984-06-20 1990-11-06 Merck & Co., Inc. Controlled porosity osmotic pump
US4624847A (en) * 1985-04-22 1986-11-25 Alza Corporation Drug delivery device for programmed delivery of beneficial drug
GB8518301D0 (en) * 1985-07-19 1985-08-29 Fujisawa Pharmaceutical Co Hydrodynamically explosive systems
US4865598A (en) * 1985-08-16 1989-09-12 Alza Corporation Dispensing system for administering beneficial agent
DE3868077D1 (de) * 1987-01-14 1992-03-12 Ciba Geigy Ag Therapeutisches system fuer schwerloesliche wirkstoffe.
US4851232A (en) * 1987-02-13 1989-07-25 Alza Corporation Drug delivery system with means for obtaining desirable in vivo release rate pattern
US4795641A (en) * 1987-08-20 1989-01-03 Eastman Kodak Company Polymer blends having reverse phase morphology for controlled delivery of bioactive agents
US5612059A (en) 1988-08-30 1997-03-18 Pfizer Inc. Use of asymmetric membranes in delivery devices
US5096716A (en) * 1988-09-01 1992-03-17 Alza Corporation Dosage form for administering calcium antagonist nicardipine
US5034229A (en) * 1988-12-13 1991-07-23 Alza Corporation Dispenser for increasing feed conversion of hog
US5110596A (en) * 1988-12-13 1992-05-05 Alza Corporation Delivery system comprising means for delivering agent to livestock
IL92966A (en) * 1989-01-12 1995-07-31 Pfizer Hydrogel-operated release devices
US5186942A (en) * 1989-01-30 1993-02-16 Alza Corporation Nicardipine therapy
DD295760A5 (de) * 1989-01-31 1991-11-14 Martin-Luther-Universitaet Halle Wittenberg,De Arzneistoffreigabesystem mit kotrollierter wirkstoffreisetzung
US5019396A (en) * 1989-05-12 1991-05-28 Alza Corporation Delivery dispenser for treating cardiac arrhythmias
US5776493A (en) * 1989-07-14 1998-07-07 Alza Corporation Oral osmotic device for delivery of nystatin with hydrogel driving member
US5126142A (en) * 1989-07-18 1992-06-30 Alza Corporation Dispenser comprising ionophore
US5273752A (en) * 1989-07-18 1993-12-28 Alza Corporation Controlled release dispenser comprising beneficial agent
US5035897A (en) * 1989-09-05 1991-07-30 Alza Corporation Dosage form for delivering soluble or insoluble drugs
US5091190A (en) * 1989-09-05 1992-02-25 Alza Corporation Delivery system for administration blood-glucose lowering drug
US5120548A (en) * 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
US5200197A (en) * 1989-11-16 1993-04-06 Alza Corporation Contraceptive pill
US5151450A (en) * 1990-02-22 1992-09-29 Tokyo Tanabe Company, Limited Antiulcer substance
US5190763A (en) * 1990-05-07 1993-03-02 Alza Corporation Dosage form indicated for the management of abnormal posture, tremor and involuntary movement
US5192550A (en) * 1990-05-07 1993-03-09 Alza Corporation Dosage form for treating central nervous system disorders
US5221536A (en) * 1990-05-07 1993-06-22 Alza Corporation Dosage form indicated for the management of abnormal posture, tremor and involuntary movement
US5128145A (en) * 1990-06-13 1992-07-07 Alza Corporation Dosage form for Parkinson's disease, spasticity and muscle spasms
JP2558396B2 (ja) * 1990-06-28 1996-11-27 田辺製薬株式会社 放出制御型製剤
US5156850A (en) * 1990-08-31 1992-10-20 Alza Corporation Dosage form for time-varying patterns of drug delivery
CA2089738C (en) * 1990-09-28 1997-01-21 Avinash Govind Thombre Dispensing device containing a hydrophobic medium
US5160744A (en) * 1991-06-27 1992-11-03 Alza Corporation Verapmil therapy
AU2867492A (en) * 1991-10-10 1993-05-03 Alza Corporation Osmotic drug delivery devices with hydrophobic wall materials
US5200195A (en) * 1991-12-06 1993-04-06 Alza Corporation Process for improving dosage form delivery kinetics
US5185158A (en) * 1992-02-27 1993-02-09 Alza Corporation Dosage form comprising succinimide drug for treating depressive disorders and composition comprising same
KR100355130B1 (ko) * 1992-09-18 2003-01-30 야마노우치세이야쿠 가부시키가이샤 하이드로겔서방성정제
US5358721A (en) * 1992-12-04 1994-10-25 Alza Corporation Antiviral therapy
DE69425453T2 (de) * 1993-04-23 2001-04-12 Novartis Ag Wirkstoffabgabevorrichtung mit gesteuerter Freigabe
US6287598B1 (en) * 1993-05-28 2001-09-11 Alza Corporation Method for providing sustained antiepileptic therapy
HU213407B (en) * 1993-12-09 1997-06-30 Egyt Gyogyszervegyeszeti Gyar Process for producing tablet with diffusive-osmotic release
GB9326267D0 (en) * 1993-12-23 1994-02-23 Scherer Corp R P Expulsion of material
US5458887A (en) * 1994-03-02 1995-10-17 Andrx Pharmaceuticals, Inc. Controlled release tablet formulation
US5458888A (en) * 1994-03-02 1995-10-17 Andrx Pharmaceuticals, Inc. Controlled release tablet formulation
ES2163504T5 (es) * 1994-05-06 2008-05-16 Pfizer Inc. Formas de dosificacion de liberacion controlada de azitromicina.
US5698224A (en) * 1994-06-27 1997-12-16 Alza Corporation Tacrine therapy
US5529787A (en) * 1994-07-07 1996-06-25 Alza Corporation Hydromorphone therapy
US5582591A (en) * 1994-09-02 1996-12-10 Delab Delivery of solid drug compositions
US5718700A (en) * 1994-09-20 1998-02-17 Alza Corporation Exit means in dosage form
US5614578A (en) * 1994-10-28 1997-03-25 Alza Corporation Injection-molded dosage form
US5607696A (en) * 1995-02-10 1997-03-04 Alza Corporation Osmotic membrane and delivery device
US5736159A (en) * 1995-04-28 1998-04-07 Andrx Pharmaceuticals, Inc. Controlled release formulation for water insoluble drugs in which a passageway is formed in situ
US5817335A (en) * 1995-05-26 1998-10-06 Alza Corporation Osmotic device with high drug loading and delayed activation of drug delivery
US5654005A (en) * 1995-06-07 1997-08-05 Andrx Pharmaceuticals, Inc. Controlled release formulation having a preformed passageway
US5840332A (en) * 1996-01-18 1998-11-24 Perio Products Ltd. Gastrointestinal drug delivery system
FR2744733B1 (fr) * 1996-02-08 1998-04-24 Ascometal Sa Acier pour la fabrication de piece forgee et procede de fabrication d'une piece forgee
IT1290764B1 (it) * 1996-05-03 1998-12-10 Vevy Europ S P A Pentapeptide per la preparazione di composizioni dermo- farmaceutiche e cosmetiche per il trattamento di lesioni od affezioni cutanee
US5837379A (en) * 1997-01-31 1998-11-17 Andrx Pharmaceuticals, Inc. Once daily pharmaceutical tablet having a unitary core
US6271278B1 (en) * 1997-05-13 2001-08-07 Purdue Research Foundation Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties
DE69818607T2 (de) * 1997-05-30 2004-07-29 Osmotica Corp. Mehrlagige osmosevorrichtung
ES2287971T3 (es) * 1997-08-11 2007-12-16 Pfizer Products Inc. Dispersiones farmaceuticas solidas con biodisponibilidad incrementada.
DE19737463A1 (de) * 1997-08-28 1999-03-04 Hoechst Marion Roussel De Gmbh Verwendung von Inhibitoren des Natrium-Wasserstoff-Austauschers zur Herstellung eines Arzneimittels zur Behandlung von Erkrankungen, die durch Protozoen verursacht werden
US6037346A (en) * 1997-10-28 2000-03-14 Vivus, Inc. Local administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction
EP1027888B1 (en) * 1999-02-10 2009-06-10 Pfizer Products Inc. Osmotic system for delivery of solid amorphous dispersions of drugs
US6706283B1 (en) 1999-02-10 2004-03-16 Pfizer Inc Controlled release by extrusion of solid amorphous dispersions of drugs
US6245200B1 (en) 1999-12-10 2001-06-12 Sandia Corporation Photo-oxidation method using MoS2 nanocluster materials
WO2001047498A2 (en) * 1999-12-23 2001-07-05 Pfizer Products Inc. Hydrogel-driven layered drug dosage form comprising sertraline
US20030086972A1 (en) * 2000-08-09 2003-05-08 Appel Leah E. Hydrogel-driven drug dosage form

Also Published As

Publication number Publication date
DZ3228A1 (fr) 2001-07-05
CR6656A (es) 2004-04-29
US9028870B2 (en) 2015-05-12
CZ20022046A3 (cs) 2002-11-13
NZ518281A (en) 2005-01-28
PL357535A1 (en) 2004-07-26
PE20010985A1 (es) 2001-09-28
MA26859A1 (fr) 2004-12-20
OA12128A (en) 2006-05-05
EA004370B1 (ru) 2004-04-29
CN1402632A (zh) 2003-03-12
SV2002000250A (es) 2002-02-05
EP1967185A1 (en) 2008-09-10
US20020015731A1 (en) 2002-02-07
AP2002002553A0 (en) 2002-06-30
DE60038698D1 (de) 2008-06-05
EE200200361A (et) 2003-10-15
MXPA02006328A (es) 2002-12-13
DK1242055T3 (da) 2008-07-21
US20070087057A1 (en) 2007-04-19
WO2001047500A1 (en) 2001-07-05
JP4100910B2 (ja) 2008-06-11
HUP0301242A3 (en) 2006-07-28
ATE392890T1 (de) 2008-05-15
BG106865A (bg) 2003-03-31
AU783685B2 (en) 2005-11-24
EP1242055B1 (en) 2008-04-23
ZA200204960B (en) 2003-10-02
JP2003518489A (ja) 2003-06-10
TNSN00253A1 (fr) 2002-05-30
EA200200595A1 (ru) 2002-12-26
SK8572002A3 (en) 2002-12-03
NO20022970D0 (no) 2002-06-20
KR20020070330A (ko) 2002-09-05
US20110182947A1 (en) 2011-07-28
CA2395333A1 (en) 2001-07-05
KR100523127B1 (ko) 2005-10-20
BR0016708A (pt) 2002-10-08
GT200000222A (es) 2002-06-14
AR027091A1 (es) 2003-03-12
CA2395333C (en) 2009-01-13
YU35302A (sh) 2005-03-15
SI1242055T1 (sl) 2008-08-31
PA8509001A1 (es) 2002-02-21
NO20022970L (no) 2002-06-20
IS6340A (is) 2002-04-12
IL149224A0 (en) 2002-11-10
TR200201646T2 (tr) 2002-11-21
EP1242055A1 (en) 2002-09-25
ES2302705T3 (es) 2008-08-01
DE60038698T2 (de) 2009-05-07
AU2018901A (en) 2001-07-09
HUP0301242A2 (hu) 2004-05-28
GEP20043334B (en) 2004-03-10

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