PT1223990E - Formulacoes de acido hialuronico para administracao de proteinas osteogenicas - Google Patents
Formulacoes de acido hialuronico para administracao de proteinas osteogenicasInfo
- Publication number
- PT1223990E PT1223990E PT00970914T PT00970914T PT1223990E PT 1223990 E PT1223990 E PT 1223990E PT 00970914 T PT00970914 T PT 00970914T PT 00970914 T PT00970914 T PT 00970914T PT 1223990 E PT1223990 E PT 1223990E
- Authority
- PT
- Portugal
- Prior art keywords
- hyaluronic acid
- administration
- osteogenic proteins
- acid formulations
- injectable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Composite Materials (AREA)
- Materials Engineering (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15967499P | 1999-10-15 | 1999-10-15 | |
US18558700P | 2000-02-28 | 2000-02-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1223990E true PT1223990E (pt) | 2004-12-31 |
Family
ID=26856175
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT00970914T PT1223990E (pt) | 1999-10-15 | 2000-10-13 | Formulacoes de acido hialuronico para administracao de proteinas osteogenicas |
Country Status (11)
Country | Link |
---|---|
US (2) | US7189392B1 (pt) |
EP (2) | EP2286847A1 (pt) |
JP (1) | JP4703926B2 (pt) |
AT (1) | ATE271886T1 (pt) |
AU (2) | AU774427B2 (pt) |
CA (1) | CA2386408A1 (pt) |
DE (1) | DE60012557T2 (pt) |
DK (1) | DK1223990T3 (pt) |
ES (1) | ES2225241T3 (pt) |
PT (1) | PT1223990E (pt) |
WO (1) | WO2001028602A1 (pt) |
Families Citing this family (32)
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US7582311B1 (en) * | 1999-10-15 | 2009-09-01 | Genentech, Inc. | Injection vehicle for polymer-based formulations |
JP4703926B2 (ja) * | 1999-10-15 | 2011-06-15 | ジェネティクス インスティテュート,エルエルシー | 骨形成蛋白をデリバリーするためのヒアルロン酸の処方 |
US20020114795A1 (en) | 2000-12-22 | 2002-08-22 | Thorne Kevin J. | Composition and process for bone growth and repair |
AU2007203555B2 (en) * | 2001-06-08 | 2009-01-08 | Etex Corporation | Calcium Phosphate Delivery Vehicles for Osteoinductive Proteins |
TWI267378B (en) | 2001-06-08 | 2006-12-01 | Wyeth Corp | Calcium phosphate delivery vehicles for osteoinductive proteins |
BR0214275A (pt) | 2001-11-19 | 2004-09-21 | Scil Technology Gmbh | Dispositivo tendo propriedades osteocondutora e osteoindutora |
JP4879482B2 (ja) * | 2002-05-17 | 2012-02-22 | ワイス・エルエルシー | 骨原性タンパク質を送達するための注入可能な固体ヒアルロン酸キャリア |
ES2260685T3 (es) | 2002-09-10 | 2006-11-01 | Scil Technology Gmbh | Implante metalico recubierto, a una concentracion de oxigeno reducida, con proteina osteoinductora. |
EP1675608B1 (en) * | 2003-09-12 | 2007-03-21 | Wyeth | Injectable calcium phosphate solid rods for delivery of osteogenic proteins |
ES2350939T3 (es) | 2004-03-10 | 2011-01-28 | Scil Technology Gmbh | Implantes recubiertos, su fabricación y uso de los mismos. |
ES2246695B1 (es) | 2004-04-29 | 2007-05-01 | Instituto Cientifico Y Tecnologico De Navarra, S.A. | Composicion estimuladora de la respuesta inmunitaria que comprende nanoparticulas a base de un copolimero de metil vinil eter y anhidrido maleico. |
ES2246694B1 (es) | 2004-04-29 | 2007-05-01 | Instituto Cientifico Y Tecnologico De Navarra, S.A. | Nanoparticulas pegiladas. |
ITPD20040312A1 (it) * | 2004-12-15 | 2005-03-15 | Fidia Advanced Biopolymers Srl | Protesi e o supporto per la sostituzione, riparazione, rigenerazione del menisco |
US8048857B2 (en) | 2006-12-19 | 2011-11-01 | Warsaw Orthopedic, Inc. | Flowable carrier compositions and methods of use |
US7718616B2 (en) | 2006-12-21 | 2010-05-18 | Zimmer Orthobiologics, Inc. | Bone growth particles and osteoinductive composition thereof |
FR2919188B1 (fr) * | 2007-07-27 | 2010-02-26 | Proteins & Peptides Man | Complexes entre un polymere amphiphile et une proteine osteogenique appartenant a la famille des bmps |
AU2008322629B2 (en) | 2007-11-13 | 2013-05-16 | Bio-Technology General (Israel) Ltd. | Dilute filtration sterilization process for viscoelastic biopolymers |
US9320761B2 (en) | 2008-12-18 | 2016-04-26 | Vivex Biomedical, Inc. | Bone induction system and methods |
US8613938B2 (en) | 2010-11-15 | 2013-12-24 | Zimmer Orthobiologics, Inc. | Bone void fillers |
US8455436B2 (en) | 2010-12-28 | 2013-06-04 | Depuy Mitek, Llc | Compositions and methods for treating joints |
US8524662B2 (en) | 2010-12-28 | 2013-09-03 | Depuy Mitek, Llc | Compositions and methods for treating joints |
US8398611B2 (en) | 2010-12-28 | 2013-03-19 | Depuy Mitek, Inc. | Compositions and methods for treating joints |
US9265830B2 (en) | 2011-04-20 | 2016-02-23 | Warsaw Orthopedic, Inc. | Implantable compositions and methods for preparing the same |
US8623839B2 (en) | 2011-06-30 | 2014-01-07 | Depuy Mitek, Llc | Compositions and methods for stabilized polysaccharide formulations |
RU2533017C1 (ru) * | 2013-06-25 | 2014-11-20 | Федеральное государственное бюджетное учреждение "Саратовский научно-исследовательский институт травматологии и ортопедии" Министерства здравоохранения Российской Федерации (ФГБУ "СарНИИТО" Минздрава России) | Способ лечения кистозных образований длинных трубчатых костей |
US9682099B2 (en) | 2015-01-20 | 2017-06-20 | DePuy Synthes Products, Inc. | Compositions and methods for treating joints |
JP6759220B2 (ja) * | 2015-01-28 | 2020-09-23 | アラーガン、インコーポレイテッドAllergan,Incorporated | 関節脂肪パッド製剤、およびその使用方法 |
EP3297694A1 (en) | 2015-05-21 | 2018-03-28 | Musculoskeletal Transplant Foundation | Modified demineralized cortical bone fibers |
US10675330B2 (en) * | 2018-03-21 | 2020-06-09 | Warsaw Orthopedic, Inc. | Injectable bone morphogenetic protein |
CN108324994B (zh) * | 2018-04-26 | 2020-12-01 | 海口市人民医院(中南大学湘雅医学院附属海口医院) | 珍珠粉人工骨的制备方法 |
US11324806B2 (en) | 2018-10-19 | 2022-05-10 | Warsaw Orthopedic, Inc. | Sustained delivery of a growth differentiation factor |
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-
2000
- 2000-10-13 JP JP2001531430A patent/JP4703926B2/ja not_active Expired - Fee Related
- 2000-10-13 AU AU80230/00A patent/AU774427B2/en not_active Ceased
- 2000-10-13 US US09/687,281 patent/US7189392B1/en not_active Expired - Fee Related
- 2000-10-13 AT AT00970914T patent/ATE271886T1/de not_active IP Right Cessation
- 2000-10-13 DK DK00970914T patent/DK1223990T3/da active
- 2000-10-13 DE DE60012557T patent/DE60012557T2/de not_active Revoked
- 2000-10-13 EP EP10182996A patent/EP2286847A1/en not_active Withdrawn
- 2000-10-13 ES ES00970914T patent/ES2225241T3/es not_active Expired - Lifetime
- 2000-10-13 PT PT00970914T patent/PT1223990E/pt unknown
- 2000-10-13 CA CA002386408A patent/CA2386408A1/en not_active Abandoned
- 2000-10-13 EP EP00970914A patent/EP1223990B1/en not_active Revoked
- 2000-10-13 WO PCT/US2000/028468 patent/WO2001028602A1/en active Search and Examination
-
2004
- 2004-07-30 AU AU2004203514A patent/AU2004203514B2/en not_active Ceased
-
2007
- 2007-01-18 US US11/624,463 patent/US7608580B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1223990A1 (en) | 2002-07-24 |
US20070134342A1 (en) | 2007-06-14 |
CA2386408A1 (en) | 2001-04-26 |
DE60012557T2 (de) | 2005-08-04 |
ATE271886T1 (de) | 2004-08-15 |
US7189392B1 (en) | 2007-03-13 |
DE60012557D1 (de) | 2004-09-02 |
EP2286847A1 (en) | 2011-02-23 |
DK1223990T3 (da) | 2004-11-29 |
AU2004203514B2 (en) | 2006-08-10 |
US7608580B2 (en) | 2009-10-27 |
WO2001028602A1 (en) | 2001-04-26 |
AU2004203514A1 (en) | 2004-08-26 |
ES2225241T3 (es) | 2005-03-16 |
AU774427B2 (en) | 2004-06-24 |
AU8023000A (en) | 2001-04-30 |
JP4703926B2 (ja) | 2011-06-15 |
EP1223990B1 (en) | 2004-07-28 |
JP2003512341A (ja) | 2003-04-02 |
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