PT100965B - Composicoes farmaceuticas compreendendo compostos de di-terc-butilfenol uteis como agentes anti-inflamatorios - Google Patents
Composicoes farmaceuticas compreendendo compostos de di-terc-butilfenol uteis como agentes anti-inflamatorios Download PDFInfo
- Publication number
- PT100965B PT100965B PT100965A PT10096592A PT100965B PT 100965 B PT100965 B PT 100965B PT 100965 A PT100965 A PT 100965A PT 10096592 A PT10096592 A PT 10096592A PT 100965 B PT100965 B PT 100965B
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- Portugal
- Prior art keywords
- compound
- dimethylethyl
- hydroxyphenyl
- bis
- pharmaceutically acceptable
- Prior art date
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- 208000024891 symptom Diseases 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- GETQZCLCWQTVFV-UHFFFAOYSA-N trimethylamine Chemical group CN(C)C GETQZCLCWQTVFV-UHFFFAOYSA-N 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
- C07C235/76—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C235/78—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77785591A | 1991-10-16 | 1991-10-16 | |
| US07/951,547 US5280045A (en) | 1991-10-16 | 1992-10-01 | 4(3,5-bis(1,1-dimethylethyl-4-hydroxyphenyl)-4-oxobutanamide compound useful as an anti-inflammatory agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT100965A PT100965A (pt) | 1994-02-28 |
| PT100965B true PT100965B (pt) | 1999-07-30 |
Family
ID=27119370
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT100965A PT100965B (pt) | 1991-10-16 | 1992-10-15 | Composicoes farmaceuticas compreendendo compostos de di-terc-butilfenol uteis como agentes anti-inflamatorios |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5280045A (en:Method) |
| AU (1) | AU2875992A (en:Method) |
| MA (1) | MA22681A1 (en:Method) |
| MX (1) | MX9205938A (en:Method) |
| MY (1) | MY110087A (en:Method) |
| NZ (1) | NZ244746A (en:Method) |
| PT (1) | PT100965B (en:Method) |
| SG (1) | SG68551A1 (en:Method) |
| TW (1) | TW267155B (en:Method) |
| WO (1) | WO1993007865A1 (en:Method) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9408334A (pt) * | 1993-12-17 | 1997-08-19 | Procter & Gamble | Compostos de di-ter-butilfenol úteis como agentes antiinflamatórios |
| US5684204A (en) * | 1995-11-15 | 1997-11-04 | The Procter & Gamble Company | Sulfur containing di-tert-butylphenol compounds useful as anti-inflammatory agents |
| US20030129186A1 (en) | 2001-07-25 | 2003-07-10 | Biomarin Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| US7479507B2 (en) * | 2003-01-14 | 2009-01-20 | Adam Heller | Anti-inflammatory substituted phenols and elastomeric compositions for oral delivery of drugs |
| US20050003024A1 (en) * | 2003-03-04 | 2005-01-06 | The Procter & Gamble Company | Regulation of mammalian hair growth |
| US20050255060A1 (en) * | 2004-05-10 | 2005-11-17 | Oblong John E | Personal care compositions and methods regulating mammalian hair growth |
| US20050255059A1 (en) * | 2004-05-10 | 2005-11-17 | Oblong John E | Personal care compositions and methods regulating mammalian hair growth |
| EP3827747A1 (en) | 2005-04-28 | 2021-06-02 | Otsuka Pharmaceutical Co., Ltd. | Pharma-informatics system |
| US20070203240A1 (en) * | 2006-02-27 | 2007-08-30 | The Procter & Gamble Company | Personal care compositions and methods for regulating mammalian hair growth |
| US8795627B2 (en) | 2007-03-21 | 2014-08-05 | Raptor Pharmaceuticals Inc. | Treatment of liver disorders by administration of RAP conjugates |
| PT3395372T (pt) | 2009-02-20 | 2022-05-05 | Enhanx Biopharm Inc | Sistema de entrega de medicamentos à base de glutationa |
| KR101741629B1 (ko) | 2009-05-06 | 2017-05-31 | 라보라토리 스킨 케어, 인크. | 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법 |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3784701A (en) * | 1970-09-21 | 1974-01-08 | American Cyanamid Co | Compositions containing substituted benzoylpropionic acids and method of use to treat inflammation and pain |
| GB1498903A (en) * | 1974-03-25 | 1978-01-25 | Fabre Sa Pierre | Aromatic keto-acids and their derivatives |
| US4130666A (en) * | 1977-05-16 | 1978-12-19 | Riker Laboratories, Inc. | Anti-inflammatory method |
| DE3047106A1 (de) * | 1980-12-13 | 1982-07-29 | Henkel Kgaa | Topische kosmetische zubereitungen zur behandlung von stark fettendem haar und seborrhoeischer haut |
| IT1171604B (it) * | 1981-10-22 | 1987-06-10 | Roussel Maestretti Spa | Derivati di acido 4-fenil-4-ossobuten-2-oico dotati di proprieta' farmacologiche e loro procedimento di preparazione |
| US4714776A (en) * | 1985-07-22 | 1987-12-22 | Riker Laboratories, Inc. | Antiallergic agents |
| US4708966A (en) * | 1986-06-27 | 1987-11-24 | The Procter & Gamble Company | Novel anti-inflammatory agents, pharmaceutical compositions and methods for reducing inflammation |
| US4968710A (en) * | 1987-11-13 | 1990-11-06 | Riker Laboratories, Inc. | Substituted di-t-butylphenols and anti-allergic use thereof |
| JP2976813B2 (ja) * | 1994-07-05 | 1999-11-10 | セイコーエプソン株式会社 | 潜水用電子時計 |
-
1992
- 1992-10-01 US US07/951,547 patent/US5280045A/en not_active Expired - Fee Related
- 1992-10-12 WO PCT/US1992/008742 patent/WO1993007865A1/en active Application Filing
- 1992-10-12 SG SG1996002946A patent/SG68551A1/en unknown
- 1992-10-12 AU AU28759/92A patent/AU2875992A/en not_active Abandoned
- 1992-10-15 NZ NZ244746A patent/NZ244746A/en unknown
- 1992-10-15 MX MX9205938A patent/MX9205938A/es not_active IP Right Cessation
- 1992-10-15 PT PT100965A patent/PT100965B/pt not_active IP Right Cessation
- 1992-10-15 MY MYPI92001860A patent/MY110087A/en unknown
- 1992-10-16 MA MA22968A patent/MA22681A1/fr unknown
- 1992-11-04 TW TW081108788A patent/TW267155B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| NZ244746A (en) | 1995-06-27 |
| MY110087A (en) | 1997-12-31 |
| PT100965A (pt) | 1994-02-28 |
| AU2875992A (en) | 1993-05-21 |
| MX9205938A (es) | 1993-05-01 |
| MA22681A1 (fr) | 1993-07-01 |
| TW267155B (en:Method) | 1996-01-01 |
| SG68551A1 (en) | 1999-11-16 |
| US5280045A (en) | 1994-01-18 |
| WO1993007865A1 (en) | 1993-04-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19930608 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19990419 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20021031 |