PL79435B1 - Certain pyridyl-1 2 4-oxadiazole derivatives[us3647809a] - Google Patents

Certain pyridyl-1 2 4-oxadiazole derivatives[us3647809a] Download PDF

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Publication number
PL79435B1
PL79435B1 PL1969133199A PL13319969A PL79435B1 PL 79435 B1 PL79435 B1 PL 79435B1 PL 1969133199 A PL1969133199 A PL 1969133199A PL 13319969 A PL13319969 A PL 13319969A PL 79435 B1 PL79435 B1 PL 79435B1
Authority
PL
Poland
Prior art keywords
formula
pyridyl
acid
compound
optionally substituted
Prior art date
Application number
PL1969133199A
Other languages
English (en)
Polish (pl)
Original Assignee
Chinoin Gyogyszeres Vegyeszeti Termekek Gyara Rt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszeres Vegyeszeti Termekek Gyara Rt filed Critical Chinoin Gyogyszeres Vegyeszeti Termekek Gyara Rt
Publication of PL79435B1 publication Critical patent/PL79435B1/pl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
PL1969133199A 1968-04-26 1969-04-25 Certain pyridyl-1 2 4-oxadiazole derivatives[us3647809a] PL79435B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUCI000796 1968-04-26

Publications (1)

Publication Number Publication Date
PL79435B1 true PL79435B1 (en) 1975-06-30

Family

ID=10994349

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1969133199A PL79435B1 (en) 1968-04-26 1969-04-25 Certain pyridyl-1 2 4-oxadiazole derivatives[us3647809a]

Country Status (15)

Country Link
US (1) US3647809A (enExample)
JP (1) JPS4824394B1 (enExample)
AT (2) AT292728B (enExample)
BE (1) BE732131A (enExample)
BR (1) BR6908381D0 (enExample)
CA (1) CA954858A (enExample)
CH (2) CH542232A (enExample)
DE (1) DE1920037A1 (enExample)
FR (1) FR2007529B1 (enExample)
GB (1) GB1271302A (enExample)
IL (1) IL31990A (enExample)
NL (1) NL6906401A (enExample)
NO (1) NO124253B (enExample)
PL (1) PL79435B1 (enExample)
SE (1) SE368576B (enExample)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3853893A (en) * 1973-04-02 1974-12-10 Squibb & Sons Inc Anthelmintic 5-(pyridyl)-3-(isothiocyanophenyl) oxadiazoles
HU177086B (en) * 1975-06-09 1981-07-28 Eszakmagyar Vegyimuevek Herbicide and fungicide preparation containing substituted 1,2,4-oxadiazolidin-3-one derivatives
JPS58150576A (ja) * 1982-03-03 1983-09-07 Sumitomo Chem Co Ltd 新規な１，２，４−オキサジアゾ−ル誘導体
DE3247118A1 (de) * 1982-12-20 1984-06-20 Cassella Ag, 6000 Frankfurt Neue substituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
EP1582519A3 (en) * 1999-08-19 2005-12-21 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
KR100875222B1 (ko) * 1999-08-19 2008-12-19 아스트라제네카 아베 헤테로폴리사이클릭 화합물 및 간접 글루타메이트 수용체길항제로서의 그들의 용도
US6660753B2 (en) * 1999-08-19 2003-12-09 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
ES2292830T3 (es) * 2001-02-21 2008-03-16 Astrazeneca Ab Compuestos heteropoliciclicos y su uso como antagonistas del receptor metabotropico de glutamato.
CA2495179A1 (en) 2002-08-09 2004-02-19 Astrazeneca Ab Compounds having an activity at metabotropic glutamate receptors
CA2520255C (en) * 2003-04-09 2014-07-08 Exelixis, Inc. Tie-2 modulators and methods of use
WO2004103279A2 (en) * 2003-05-15 2004-12-02 Merck & Co., Inc. 3-(2-amino-1-azacyclyl)-5-aryl-1,2,4-oxadiazoles as s1p receptor agonists
US20060189661A1 (en) * 2003-11-03 2006-08-24 Wagenen Bradford V Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
WO2005060961A2 (en) * 2003-12-18 2005-07-07 Astrazeneca Ab Treatment of transient lower esophageal sphincter relaxations (tlesrs) and gastro-esophageal reflux disease (gerd)
CN1898235A (zh) * 2003-12-24 2007-01-17 普罗西迪恩有限公司 作为gpcr受体激动剂的杂环衍生物
WO2005077368A2 (en) * 2004-02-03 2005-08-25 Astrazeneca Ab Treatment of gastro-esophageal reflux disease (gerd)
RU2007139255A (ru) * 2005-04-26 2009-06-10 Ньюросерч А/С (DK) Новые оксадиазольные производные и их медицинское применение
IL169855A (en) * 2005-07-25 2014-05-28 Elta Systems Ltd A system and method for locating a receiver location
KR101370280B1 (ko) 2005-07-26 2014-03-06 바이알 - 포르텔라 앤드 씨에이 에스에이 Ｃｏｍｔ 억제제로서의 니트로카테콜 유도체
EP1845097A1 (en) * 2006-04-10 2007-10-17 Portela & Ca., S.A. Oxadiazole derivatives as COMT inhibitors
ES2400533T3 (es) * 2006-09-07 2013-04-10 Actelion Pharmaceuticals Ltd. Derivados de piridin 4-ilo como agentes inmunomoduladores
NZ576059A (en) * 2006-09-08 2012-03-30 Actelion Pharmaceuticals Ltd Pyridin-3-yl derivatives as immunomodulating agents
US8524746B2 (en) 2007-01-31 2013-09-03 Bial-Portela & Ca., S.A. Dosage regimen for COMT inhibitors
PT2125797E (pt) * 2007-03-16 2014-03-11 Actelion Pharmaceuticals Ltd Derivados aminopiridina como agonistas do receptor s1p1/edg1
MY153975A (en) * 2007-08-17 2015-04-30 Actelion Pharmaceuticals Ltd Pyridine derivatives as s1p1/edg1 receptor modulators
AU2009217865A1 (en) * 2008-02-28 2009-09-03 Bial - Portela & Ca., S.A. Pharmaceutical composition for poorly soluble drugs
ES2389042T3 (es) * 2008-03-06 2012-10-22 Actelion Pharmaceuticals Ltd. Compuestos de piridina
US8575200B2 (en) * 2008-03-07 2013-11-05 Actelion Pharmaceuticals Ltd Pyridin-2-yl derivatives as immunomodulating agents
TW200942531A (en) 2008-03-17 2009-10-16 Bial Portela & Companhia S A Crystal forms of a nitrocatechol
NZ589617A (en) * 2008-05-14 2012-06-29 Scripps Research Inst 3-(Inden-4-yl)-5-(phenyl)-1,2,4-oxadiazole and 3-(tetralin-5-yl)-5-(phenyl)-1,2,4-oxadiazole derivatives
EP3587413A1 (en) 2009-02-10 2020-01-01 Monsanto Technology LLC Compositions and methods for controlling nematodes comprising oxadiazoles
BRPI1016132B8 (pt) * 2009-04-01 2021-05-25 Bial Portela & Ca Sa composição, formulação farmacêutica, processo de obtenção de uma formulação farmacêutica estável
CN102448444B (zh) 2009-04-01 2016-05-25 巴尔-波特拉及康邦亚股份有限公司 包括硝基儿茶酚衍生物的药物制剂及其制备方法
CA2767585C (en) 2009-07-16 2017-09-26 Actelion Pharmaceuticals Ltd Pyridin-4-yl derivatives
HRP20150919T1 (hr) 2011-01-19 2015-09-25 Actelion Pharmaceuticals Ltd. Derivati 2-metoksi-piridin-4-ila
US20140045900A1 (en) 2011-02-11 2014-02-13 Bial-Portela & Ca, S.A. Administration regime for nitrocatechols
HRP20192133T8 (hr) 2011-12-13 2021-02-19 BIAL - PORTELA & Cª S.A. Kemijski spoj koristan kao posrednik za pripremu inhibitora katekol-o-metiltransferaze
WO2014127195A1 (en) 2013-02-15 2014-08-21 Monsanto Technology Llc 3,5-disubstituted-4,5-dihydro-1,2,4-oxadiazoles for controlling nematode pests
WO2016083863A1 (en) 2014-11-28 2016-06-02 Bial - Portela & Ca, S.A. Medicaments for slowing parkinson's disease
RS59788B1 (sr) 2015-05-20 2020-02-28 Idorsia Pharmaceuticals Ltd Kristalni oblik jedinjenja (s)-3-{4-[5-(2-ciklopentil-6-metoksi-piridin-4-il)-[1,2,4]oksadiazol-3-il]-2-etil-6-metil-fenoksi}-propan-1,2-diola

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL256329A (enExample) * 1959-09-29
US3227725A (en) * 1962-04-17 1966-01-04 Union Carbide Corp Certain 3,5-disubstituted 1,2,4-oxadiazole compounds

Also Published As

Publication number Publication date
IL31990A (en) 1974-05-16
DE1920037A1 (de) 1970-11-12
CH540925A (de) 1973-08-31
CA954858A (en) 1974-09-17
JPS4824394B1 (enExample) 1973-07-20
BR6908381D0 (pt) 1973-02-08
IL31990A0 (en) 1969-06-25
GB1271302A (en) 1972-04-19
NL6906401A (enExample) 1969-10-28
BE732131A (enExample) 1969-10-01
CH542232A (de) 1973-11-15
FR2007529B1 (enExample) 1973-03-16
FR2007529A1 (enExample) 1970-01-09
AT292727B (de) 1971-09-10
AT292728B (de) 1971-09-10
SE368576B (enExample) 1974-07-08
US3647809A (en) 1972-03-07
NO124253B (enExample) 1972-03-27

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