AT292727B - Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten und deren Säureadditionssalzen und quaternären Salzen - Google Patents
Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten und deren Säureadditionssalzen und quaternären SalzenInfo
- Publication number
- AT292727B AT292727B AT375469A AT375469A AT292727B AT 292727 B AT292727 B AT 292727B AT 375469 A AT375469 A AT 375469A AT 375469 A AT375469 A AT 375469A AT 292727 B AT292727 B AT 292727B
- Authority
- AT
- Austria
- Prior art keywords
- salts
- preparation
- new
- acid addition
- oxadiazole derivatives
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title 2
- 150000005071 1,2,4-oxadiazoles Chemical class 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUCI000796 | 1968-04-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AT292727B true AT292727B (de) | 1971-09-10 |
Family
ID=10994349
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT815670A AT292728B (de) | 1968-04-26 | 1969-04-18 | Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten und deren Säureadditionssalzen und quarternären Salzen |
| AT375469A AT292727B (de) | 1968-04-26 | 1969-04-18 | Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten und deren Säureadditionssalzen und quaternären Salzen |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT815670A AT292728B (de) | 1968-04-26 | 1969-04-18 | Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten und deren Säureadditionssalzen und quarternären Salzen |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US3647809A (de) |
| JP (1) | JPS4824394B1 (de) |
| AT (2) | AT292728B (de) |
| BE (1) | BE732131A (de) |
| BR (1) | BR6908381D0 (de) |
| CA (1) | CA954858A (de) |
| CH (2) | CH542232A (de) |
| DE (1) | DE1920037A1 (de) |
| FR (1) | FR2007529B1 (de) |
| GB (1) | GB1271302A (de) |
| IL (1) | IL31990A (de) |
| NL (1) | NL6906401A (de) |
| NO (1) | NO124253B (de) |
| PL (1) | PL79435B1 (de) |
| SE (1) | SE368576B (de) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3853893A (en) * | 1973-04-02 | 1974-12-10 | Squibb & Sons Inc | Anthelmintic 5-(pyridyl)-3-(isothiocyanophenyl) oxadiazoles |
| HU177086B (en) * | 1975-06-09 | 1981-07-28 | Eszakmagyar Vegyimuevek | Herbicide and fungicide preparation containing substituted 1,2,4-oxadiazolidin-3-one derivatives |
| JPS58150576A (ja) * | 1982-03-03 | 1983-09-07 | Sumitomo Chem Co Ltd | 新規な1,2,4−オキサジアゾ−ル誘導体 |
| DE3247118A1 (de) * | 1982-12-20 | 1984-06-20 | Cassella Ag, 6000 Frankfurt | Neue substituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| US6660753B2 (en) * | 1999-08-19 | 2003-12-09 | Nps Pharmaceuticals, Inc. | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| JP3790472B2 (ja) * | 1999-08-19 | 2006-06-28 | エヌピーエス ファーマシューティカルズ インコーポレーテッド | ヘテロ多環式化合物および代謝型グルタミン酸受容体アンタゴニストとしてのその使用 |
| EP1582519A3 (de) * | 1999-08-19 | 2005-12-21 | Nps Pharmaceuticals, Inc. | Heteropolycyclische verbindungen und ihre verwendung als antagonisten von metabotropen glutamatrezeptoren |
| ATE375340T1 (de) * | 2001-02-21 | 2007-10-15 | Nps Pharma Inc | Heteropolycyclische verbindungen und deren verwendung als metabotrope glutamatrezeptorantagonisten |
| WO2004014902A2 (en) * | 2002-08-09 | 2004-02-19 | Astrazeneca Ab | Compounds having an activity at metabotropic glutamate receptors |
| JP4881725B2 (ja) * | 2003-04-09 | 2012-02-22 | エクセリクシス, インク. | Tie−2モジュレータと使用方法 |
| AU2004240586A1 (en) * | 2003-05-15 | 2004-12-02 | Merck & Co., Inc. | 3-(2-amino-1-azacyclyl)-5-aryl-1,2,4-oxadiazoles as S1P receptor agonists |
| US20060189661A1 (en) * | 2003-11-03 | 2006-08-24 | Wagenen Bradford V | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| WO2005060961A2 (en) * | 2003-12-18 | 2005-07-07 | Astrazeneca Ab | Treatment of transient lower esophageal sphincter relaxations (tlesrs) and gastro-esophageal reflux disease (gerd) |
| AU2004303604B2 (en) * | 2003-12-24 | 2011-03-24 | Prosidion Limited | Heterocyclic derivatives as GPCR receptor agonists |
| WO2005077368A2 (en) * | 2004-02-03 | 2005-08-25 | Astrazeneca Ab | Treatment of gastro-esophageal reflux disease (gerd) |
| US8017631B2 (en) | 2005-04-26 | 2011-09-13 | Neurosearch A/S | Oxadiazole derivatives and their medical use |
| IL169855A (en) * | 2005-07-25 | 2014-05-28 | Elta Systems Ltd | A system and method for locating a receiver location |
| NZ565460A (en) | 2005-07-26 | 2011-06-30 | Bial Portela & Ca Sa | Nitrocatechol derivatives as COMT inhibitors |
| EP1845097A1 (de) * | 2006-04-10 | 2007-10-17 | Portela & Ca., S.A. | Oxadiazolderivate als COMT Inihibitoren |
| AR062683A1 (es) * | 2006-09-07 | 2008-11-26 | Actelion Pharmaceuticals Ltd | Compuestos derivados de piridin-4-ilo, composicion farmaceutica que los contiene, y uso de los mismos en la preparacion de medicamentos |
| AU2007292992B2 (en) * | 2006-09-08 | 2013-01-10 | Actelion Pharmaceuticals Ltd | Pyridin-3-yl derivatives as immunomodulating agents |
| WO2008094053A1 (en) * | 2007-01-31 | 2008-08-07 | Bial-Portela & Ca, S.A. | Dosage regimen for comt inhibitors |
| AU2008227979B2 (en) * | 2007-03-16 | 2014-02-06 | Actelion Pharmaceuticals Ltd | Amino- pyridine derivatives as S1P1 /EDG1 receptor agonists |
| HRP20110449T1 (hr) * | 2007-08-17 | 2011-07-31 | Actelion Pharmaceuticals Ltd. | Derivati piridina kao modulatori receptora s1p1/edg1 |
| WO2009108077A2 (en) * | 2008-02-28 | 2009-09-03 | Bial - Portela & Ca., S.A. | Pharmaceutical composition for poorly soluble drugs |
| WO2009109906A1 (en) * | 2008-03-06 | 2009-09-11 | Actelion Pharmaceuticals Ltd | Pyridine compounds |
| ES2414533T3 (es) * | 2008-03-07 | 2013-07-19 | Actelion Pharmaceuticals Ltd. | Derivados Piridin-2-ilo como agentes inmunomoduladores |
| KR20110002462A (ko) | 2008-03-17 | 2011-01-07 | 바이알 - 포르텔라 앤드 씨에이 에스에이 | 5-[3-(2,5-디클로로-4,6-디메틸-1-옥시-피리딘-3-일)-[1,2,4]옥사디아졸-5-일]-3-나이트로벤젠-1,2-디올의 결정형 |
| JP5837417B2 (ja) * | 2008-05-14 | 2015-12-24 | ザ スクリプス リサーチ インスティテュート | スフィンゴシンリン酸受容体の新規なモジュレーター |
| CN110194765A (zh) | 2009-02-10 | 2019-09-03 | 孟山都技术有限公司 | 用于控制线虫的组合物和方法 |
| KR102023255B1 (ko) | 2009-04-01 | 2019-09-19 | 바이알 - 포르텔라 앤드 씨에이 에스에이 | 니트로카테콜 유도체를 포함하는 제약 제제 및 그의 제조 방법 |
| WO2010114405A2 (en) * | 2009-04-01 | 2010-10-07 | Bial - Portela & Ca., S.A. | Pharmaceutical formulations comprising nitrocatechol derivatives and methods of making the same |
| RU2547098C2 (ru) | 2009-07-16 | 2015-04-10 | Актелион Фармасьютиклз Лтд | Производные пиридин-4-ила |
| MA34910B1 (fr) | 2011-01-19 | 2014-02-01 | Actelion Pharmaceuticals Ltd | Dérivés de 2-methoxy-pyridin-4-yl |
| US20140045900A1 (en) | 2011-02-11 | 2014-02-13 | Bial-Portela & Ca, S.A. | Administration regime for nitrocatechols |
| BR112014014341A2 (pt) | 2011-12-13 | 2017-08-22 | Bial Portela & Ca Sa | Intermediário metilado, seu método de preparação e seus usos, e composição farmacêutica |
| CA2901006A1 (en) | 2013-02-15 | 2014-08-21 | Monsanto Technology Llc | 3,5-disubstituted-4,5-dihydro-1,2,4-oxadiazoles for controlling nematode pests |
| WO2016083863A1 (en) | 2014-11-28 | 2016-06-02 | Bial - Portela & Ca, S.A. | Medicaments for slowing parkinson's disease |
| ES2770348T3 (es) | 2015-05-20 | 2020-07-01 | Idorsia Pharmaceuticals Ltd | Forma cristalina del compuesto (s)-3-{4-[5-(2-ciclopentil-6-metoxi-piridin-4-il)-[1,2,4]oxadiazol-3-il]-2-etil-6-metil-fenoxi}-propano-1,2-diol |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL256329A (de) * | 1959-09-29 | |||
| US3227725A (en) * | 1962-04-17 | 1966-01-04 | Union Carbide Corp | Certain 3,5-disubstituted 1,2,4-oxadiazole compounds |
-
1969
- 1969-04-08 IL IL31990A patent/IL31990A/xx unknown
- 1969-04-08 US US815520A patent/US3647809A/en not_active Expired - Lifetime
- 1969-04-14 GB GB09047/69A patent/GB1271302A/en not_active Expired
- 1969-04-18 AT AT815670A patent/AT292728B/de not_active IP Right Cessation
- 1969-04-18 AT AT375469A patent/AT292727B/de not_active IP Right Cessation
- 1969-04-19 DE DE19691920037 patent/DE1920037A1/de active Pending
- 1969-04-24 FR FR696912994A patent/FR2007529B1/fr not_active Expired
- 1969-04-24 CH CH1476972A patent/CH542232A/de not_active IP Right Cessation
- 1969-04-24 CH CH627569A patent/CH540925A/de not_active IP Right Cessation
- 1969-04-25 SE SE05909/69A patent/SE368576B/xx unknown
- 1969-04-25 BR BR208381/69A patent/BR6908381D0/pt unknown
- 1969-04-25 BE BE732131D patent/BE732131A/xx unknown
- 1969-04-25 NO NO1733/69A patent/NO124253B/no unknown
- 1969-04-25 NL NL6906401A patent/NL6906401A/xx unknown
- 1969-04-25 CA CA049,755A patent/CA954858A/en not_active Expired
- 1969-04-25 PL PL1969133199A patent/PL79435B1/pl unknown
- 1969-04-25 JP JP44032259A patent/JPS4824394B1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CH540925A (de) | 1973-08-31 |
| FR2007529A1 (de) | 1970-01-09 |
| CA954858A (en) | 1974-09-17 |
| FR2007529B1 (de) | 1973-03-16 |
| SE368576B (de) | 1974-07-08 |
| IL31990A (en) | 1974-05-16 |
| BE732131A (de) | 1969-10-01 |
| NO124253B (de) | 1972-03-27 |
| JPS4824394B1 (de) | 1973-07-20 |
| NL6906401A (de) | 1969-10-28 |
| IL31990A0 (en) | 1969-06-25 |
| GB1271302A (en) | 1972-04-19 |
| AT292728B (de) | 1971-09-10 |
| US3647809A (en) | 1972-03-07 |
| BR6908381D0 (pt) | 1973-02-08 |
| PL79435B1 (en) | 1975-06-30 |
| DE1920037A1 (de) | 1970-11-12 |
| CH542232A (de) | 1973-11-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |