IL31990A - Pyridyl 1,2,4-oxadiazole derivatives,process for the preparation thereof and pharmaceutical compositions containing same - Google Patents
Pyridyl 1,2,4-oxadiazole derivatives,process for the preparation thereof and pharmaceutical compositions containing sameInfo
- Publication number
- IL31990A IL31990A IL31990A IL3199069A IL31990A IL 31990 A IL31990 A IL 31990A IL 31990 A IL31990 A IL 31990A IL 3199069 A IL3199069 A IL 3199069A IL 31990 A IL31990 A IL 31990A
- Authority
- IL
- Israel
- Prior art keywords
- pyridyl
- preparation
- pharmaceutical compositions
- compositions containing
- containing same
- Prior art date
Links
- ZAAIEOSUVDRLGD-UHFFFAOYSA-N 3-pyridin-2-yl-1,2,4-oxadiazole Chemical class O1C=NC(C=2N=CC=CC=2)=N1 ZAAIEOSUVDRLGD-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUCI000796 | 1968-04-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL31990A0 IL31990A0 (en) | 1969-06-25 |
| IL31990A true IL31990A (en) | 1974-05-16 |
Family
ID=10994349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL31990A IL31990A (en) | 1968-04-26 | 1969-04-08 | Pyridyl 1,2,4-oxadiazole derivatives,process for the preparation thereof and pharmaceutical compositions containing same |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US3647809A (de) |
| JP (1) | JPS4824394B1 (de) |
| AT (2) | AT292727B (de) |
| BE (1) | BE732131A (de) |
| BR (1) | BR6908381D0 (de) |
| CA (1) | CA954858A (de) |
| CH (2) | CH540925A (de) |
| DE (1) | DE1920037A1 (de) |
| FR (1) | FR2007529B1 (de) |
| GB (1) | GB1271302A (de) |
| IL (1) | IL31990A (de) |
| NL (1) | NL6906401A (de) |
| NO (1) | NO124253B (de) |
| PL (1) | PL79435B1 (de) |
| SE (1) | SE368576B (de) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3853893A (en) * | 1973-04-02 | 1974-12-10 | Squibb & Sons Inc | Anthelmintic 5-(pyridyl)-3-(isothiocyanophenyl) oxadiazoles |
| HU177086B (en) * | 1975-06-09 | 1981-07-28 | Eszakmagyar Vegyimuevek | Herbicide and fungicide preparation containing substituted 1,2,4-oxadiazolidin-3-one derivatives |
| JPS58150576A (ja) * | 1982-03-03 | 1983-09-07 | Sumitomo Chem Co Ltd | 新規な１，２，４−オキサジアゾ−ル誘導体 |
| DE3247118A1 (de) * | 1982-12-20 | 1984-06-20 | Cassella Ag, 6000 Frankfurt | Neue substituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE60023318T2 (de) * | 1999-08-19 | 2006-07-20 | NPS Pharmaceuticals, Inc., Salt Lake City | Heteropolycyclische verbindungen und ihre verwendung als antagonisten von metabotropen glutamatrezeptoren |
| EP1582519A3 (de) * | 1999-08-19 | 2005-12-21 | Nps Pharmaceuticals, Inc. | Heteropolycyclische verbindungen und ihre verwendung als antagonisten von metabotropen glutamatrezeptoren |
| US6660753B2 (en) * | 1999-08-19 | 2003-12-09 | Nps Pharmaceuticals, Inc. | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| JP4519404B2 (ja) * | 2001-02-21 | 2010-08-04 | アストラゼネカ アクチボラグ | ヘテロ多環式化合物およびその代謝型グルタミン酸受容体アンタゴニストとしての使用 |
| CA2495179A1 (en) * | 2002-08-09 | 2004-02-19 | Astrazeneca Ab | Compounds having an activity at metabotropic glutamate receptors |
| EP1611123B8 (de) * | 2003-04-09 | 2013-11-13 | Exelixis, Inc. | Tie-2-modulatoren und anwendungsverfahren |
| CN1788008A (zh) * | 2003-05-15 | 2006-06-14 | 麦克公司 | 作为s1p受体激动剂的3－(2－氨基－1－氮杂环基)－5－芳基－1,2,4－噁二唑 |
| US20060189661A1 (en) * | 2003-11-03 | 2006-08-24 | Wagenen Bradford V | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| WO2005060961A2 (en) * | 2003-12-18 | 2005-07-07 | Astrazeneca Ab | Treatment of transient lower esophageal sphincter relaxations (tlesrs) and gastro-esophageal reflux disease (gerd) |
| US8207147B2 (en) * | 2003-12-24 | 2012-06-26 | Prosidion Limited | Heterocyclic derivatives as GPCR receptor agonists |
| WO2005077368A2 (en) * | 2004-02-03 | 2005-08-25 | Astrazeneca Ab | Treatment of gastro-esophageal reflux disease (gerd) |
| RU2007139255A (ru) | 2005-04-26 | 2009-06-10 | Ньюросерч А/С (DK) | Новые оксадиазольные производные и их медицинское применение |
| IL169855A (en) * | 2005-07-25 | 2014-05-28 | Elta Systems Ltd | A system and method for locating a receiver location |
| CA2616377C (en) | 2005-07-26 | 2014-04-01 | David Alexander Learmonth | Nitrocatechol derivatives as comt inhibitors |
| EP1845097A1 (de) | 2006-04-10 | 2007-10-17 | Portela & Ca., S.A. | Oxadiazolderivate als COMT Inihibitoren |
| MY149853A (en) * | 2006-09-07 | 2013-10-31 | Actelion Pharmaceuticals Ltd | Pyridin-4-yl derivatives as immunomodulating agents |
| EP2069335B1 (de) * | 2006-09-08 | 2012-12-26 | Actelion Pharmaceuticals Ltd. | Pyridin-3-yl-derivate als immunmodulatoren |
| ES2644049T3 (es) | 2007-01-31 | 2017-11-27 | Bial - Portela & Ca., S.A. | Régimen de dosificación para inhibidores de COMT |
| CN101627034B (zh) * | 2007-03-16 | 2013-05-15 | 埃科特莱茵药品有限公司 | 氨基-吡啶衍生物作为s1p1/edg1受体激动剂 |
| US8598208B2 (en) * | 2007-08-17 | 2013-12-03 | Actelion Pharmaceuticals Ltd. | Pyridine derivatives as S1P1/EDG1 receptor modulators |
| JP2011513301A (ja) * | 2008-02-28 | 2011-04-28 | バイアル−ポルテラ アンド シーエー，エス．エー． | 難溶性薬剤のための医薬組成物 |
| ES2389042T3 (es) * | 2008-03-06 | 2012-10-22 | Actelion Pharmaceuticals Ltd. | Compuestos de piridina |
| BRPI0909055A2 (pt) * | 2008-03-07 | 2019-02-26 | Actelion Pharmaceuticals Ltd | composto derivado de piridin-2-il, composição farmacêutica que o contém e uso desse composto. |
| BRPI0908731A2 (pt) | 2008-03-17 | 2017-05-16 | Bial - Portela & C A S A | formas cristalinas de 5-[3-(2,5-dicloro-4,6-dimetil-1-óxi-piridina-3-il)[1,2,4]oxadiazol-5-il]-3-nitrobenzeno-1,2-diol |
| EP3782991A1 (de) | 2008-05-14 | 2021-02-24 | The Scripps Research Institute | Neue modulatoren von sphingosinphophatrezeptoren |
| WO2010093650A2 (en) | 2009-02-10 | 2010-08-19 | Divergence, Inc. | Compositions and methods for controlling nematodes |
| ES2730678T3 (es) * | 2009-04-01 | 2019-11-12 | Bial Portela & Ca Sa | Formulaciones farmacéuticas que comprenden derivados de nitrocatecol y métodos para fabricarlas |
| US20100256194A1 (en) * | 2009-04-01 | 2010-10-07 | Bial - Portela & Ca, S.A. | Pharmaceutical formulations comprising nitrocatechol derivatives and methods of making the same |
| MX2012000414A (es) | 2009-07-16 | 2012-02-08 | Actelion Pharmaceuticals Ltd | Derivados piridin-4-ilo. |
| MY163185A (en) | 2011-01-19 | 2017-08-15 | Idorsia Pharmaceuticals Ltd | 2-methoxy-pyridin-4-yl derivatives |
| US20140045900A1 (en) | 2011-02-11 | 2014-02-13 | Bial-Portela & Ca, S.A. | Administration regime for nitrocatechols |
| JP6456143B2 (ja) | 2011-12-13 | 2019-01-23 | ノヴィファーマ，エス．アー． | カテコール−ｏ−メチル転移酵素阻害剤を調製するための中間体として有用な化学的化合物 |
| CA2901006A1 (en) * | 2013-02-15 | 2014-08-21 | Monsanto Technology Llc | 3,5-disubstituted-4,5-dihydro-1,2,4-oxadiazoles for controlling nematode pests |
| WO2016083863A1 (en) | 2014-11-28 | 2016-06-02 | Bial - Portela & Ca, S.A. | Medicaments for slowing parkinson's disease |
| ES2770348T3 (es) | 2015-05-20 | 2020-07-01 | Idorsia Pharmaceuticals Ltd | Forma cristalina del compuesto (s)-3-{4-[5-(2-ciclopentil-6-metoxi-piridin-4-il)-[1,2,4]oxadiazol-3-il]-2-etil-6-metil-fenoxi}-propano-1,2-diol |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL120029C (de) * | 1959-09-29 | |||
| US3227725A (en) * | 1962-04-17 | 1966-01-04 | Union Carbide Corp | Certain 3,5-disubstituted 1,2,4-oxadiazole compounds |
-
1969
- 1969-04-08 IL IL31990A patent/IL31990A/xx unknown
- 1969-04-08 US US815520A patent/US3647809A/en not_active Expired - Lifetime
- 1969-04-14 GB GB09047/69A patent/GB1271302A/en not_active Expired
- 1969-04-18 AT AT375469A patent/AT292727B/de not_active IP Right Cessation
- 1969-04-18 AT AT815670A patent/AT292728B/de not_active IP Right Cessation
- 1969-04-19 DE DE19691920037 patent/DE1920037A1/de active Pending
- 1969-04-24 FR FR696912994A patent/FR2007529B1/fr not_active Expired
- 1969-04-24 CH CH627569A patent/CH540925A/de not_active IP Right Cessation
- 1969-04-24 CH CH1476972A patent/CH542232A/de not_active IP Right Cessation
- 1969-04-25 NL NL6906401A patent/NL6906401A/xx unknown
- 1969-04-25 PL PL1969133199A patent/PL79435B1/pl unknown
- 1969-04-25 BR BR208381/69A patent/BR6908381D0/pt unknown
- 1969-04-25 JP JP44032259A patent/JPS4824394B1/ja active Pending
- 1969-04-25 NO NO1733/69A patent/NO124253B/no unknown
- 1969-04-25 BE BE732131D patent/BE732131A/xx unknown
- 1969-04-25 SE SE05909/69A patent/SE368576B/xx unknown
- 1969-04-25 CA CA049,755A patent/CA954858A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AT292728B (de) | 1971-09-10 |
| AT292727B (de) | 1971-09-10 |
| FR2007529B1 (de) | 1973-03-16 |
| SE368576B (de) | 1974-07-08 |
| NL6906401A (de) | 1969-10-28 |
| CA954858A (en) | 1974-09-17 |
| PL79435B1 (en) | 1975-06-30 |
| IL31990A0 (en) | 1969-06-25 |
| FR2007529A1 (de) | 1970-01-09 |
| CH540925A (de) | 1973-08-31 |
| NO124253B (de) | 1972-03-27 |
| DE1920037A1 (de) | 1970-11-12 |
| GB1271302A (en) | 1972-04-19 |
| BE732131A (de) | 1969-10-01 |
| JPS4824394B1 (de) | 1973-07-20 |
| BR6908381D0 (pt) | 1973-02-08 |
| US3647809A (en) | 1972-03-07 |
| CH542232A (de) | 1973-11-15 |
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