IL37984A0 - 2,4-diamino-5-benzylpyrimidine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
2,4-diamino-5-benzylpyrimidine derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL37984A0 IL37984A0 IL37984A IL3798471A IL37984A0 IL 37984 A0 IL37984 A0 IL 37984A0 IL 37984 A IL37984 A IL 37984A IL 3798471 A IL3798471 A IL 3798471A IL 37984 A0 IL37984 A0 IL 37984A0
- Authority
- IL
- Israel
- Prior art keywords
- diamino
- preparation
- pharmaceutical compositions
- compositions containing
- benzylpyrimidine derivatives
- Prior art date
Links
- XHPZVBGIPQQTQW-UHFFFAOYSA-N 5-benzylpyrimidine-2,4-diamine Chemical class NC1=NC(N)=NC=C1CC1=CC=CC=C1 XHPZVBGIPQQTQW-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB963871*[A GB1375162A (en) | 1970-10-22 | 1970-10-22 | |
| GB963871 | 1971-04-16 | ||
| GB4749171 | 1971-10-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL37984A0 true IL37984A0 (en) | 1971-12-29 |
| IL37984A IL37984A (en) | 1976-03-31 |
Family
ID=27255400
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL37984A IL37984A (en) | 1970-10-22 | 1971-10-21 | 2,4-diamino-5-benzylpyrimidine derivatives,their preparation and pharmaceutical compositions containing them |
| IL45422A IL45422A (en) | 1970-10-22 | 1971-10-21 | Alpha-(3,4,5-trisubstituted benzyl)-acrylonitriles and propionitriles and their preparation |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL45422A IL45422A (en) | 1970-10-22 | 1971-10-21 | Alpha-(3,4,5-trisubstituted benzyl)-acrylonitriles and propionitriles and their preparation |
Country Status (20)
| Country | Link |
|---|---|
| JP (2) | JPS5536662B1 (en) |
| AR (3) | AR192588A1 (en) |
| AT (1) | AT319948B (en) |
| BE (1) | BE774281A (en) |
| BG (4) | BG20364A3 (en) |
| CA (1) | CA967158A (en) |
| CH (3) | CH582681A5 (en) |
| DD (1) | DD100877A5 (en) |
| DK (1) | DK132174C (en) |
| ES (1) | ES396219A1 (en) |
| FI (1) | FI56175C (en) |
| FR (1) | FR2111769B1 (en) |
| GB (1) | GB1375162A (en) |
| IE (1) | IE37452B1 (en) |
| IL (2) | IL37984A (en) |
| LU (1) | LU64129A1 (en) |
| MC (1) | MC894A1 (en) |
| NL (1) | NL175178C (en) |
| SE (2) | SE384505B (en) |
| ZM (1) | ZM14971A1 (en) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE792096A (en) * | 1971-12-01 | 1973-05-30 | Hoffmann La Roche | NEW BENZYLPYRIMIDINES |
| FR2397407A2 (en) * | 1977-07-11 | 1979-02-09 | Dick Pierre | 2,4-DIAMINO PYRIMIDINE DERIVATIVES AND THEIR SOLUTION IN ASSOCIATION WITH SULFAMIDS |
| MA18450A1 (en) * | 1978-05-24 | 1979-12-31 | Wellcome Found | COMPOSITION OF BENZYLPIRIMIDINES |
| JPS61156909A (en) * | 1984-12-27 | 1986-07-16 | Matsushita Electric Ind Co Ltd | Current mirror circuit |
| JPS62145907A (en) * | 1985-12-20 | 1987-06-30 | Hitachi Ltd | Transistor circuit |
| TWI414525B (en) | 2004-03-26 | 2013-11-11 | Dainippon Sumitomo Pharma Co | 9-substituted-8-oxoadenine compound |
| EP2041135A4 (en) | 2006-07-05 | 2010-12-01 | Astrazeneca Ab | 8-oxoadenine derivatives acting as modulators of tlr7 |
| TW200831105A (en) | 2006-12-14 | 2008-08-01 | Astrazeneca Ab | Novel compounds |
| JP5329444B2 (en) | 2007-03-19 | 2013-10-30 | アストラゼネカ・アクチエボラーグ | 9-Substituted-8-oxo-adenine compounds as TOLL-like receptor (TLR7) modulators |
| US8067413B2 (en) | 2007-03-19 | 2011-11-29 | Astrazeneca Ab | 9-substituted-8-oxo-adenine compounds as toll-like receptor (TLR7 ) modulators |
| JPWO2008114819A1 (en) | 2007-03-20 | 2010-07-08 | 大日本住友製薬株式会社 | New adenine compounds |
| PE20091236A1 (en) | 2007-11-22 | 2009-09-16 | Astrazeneca Ab | PYRIMIDINE DERIVATIVES AS IMMUNOMODULATORS OF TLR7 |
| PE20091156A1 (en) | 2007-12-17 | 2009-09-03 | Astrazeneca Ab | SALTS OF (3 - {[[3- (6-AMINO-2-BUTOXY-8-OXO-7,8-DIHIDRO-9H-PURIN-9-IL) PROPYL] (3-MORFOLIN-4-ILPROPIL) AMINO] METHYL} PHENYL) METHYL ACETATE |
| AU2010250923A1 (en) | 2009-05-21 | 2011-11-17 | Astrazeneca Ab | Novel pyrimidine derivatives and their use in the treatment of cancer and further diseases |
| GB0908772D0 (en) | 2009-05-21 | 2009-07-01 | Astrazeneca Ab | New salts 756 |
| EP2651937B8 (en) | 2010-12-16 | 2016-07-13 | Sumitomo Dainippon Pharma Co., Ltd. | Imidazo[4,5-c]quinolin-1-yl derivative useful in therapy |
| US8895570B2 (en) | 2010-12-17 | 2014-11-25 | Astrazeneca Ab | Purine derivatives |
| DK2850067T3 (en) | 2012-05-18 | 2017-11-06 | Sumitomo Dainippon Pharma Co Ltd | carboxylic acid |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE710100A (en) * | 1967-02-02 | 1968-07-30 | ||
| JPS511716A (en) * | 1974-06-25 | 1976-01-08 | Toray Industries | HORIESUTERUMARUCHIFUIRAMENTONO SEIHO |
-
1970
- 1970-10-22 GB GB963871*[A patent/GB1375162A/en not_active Expired
-
1971
- 1971-10-21 NL NLAANVRAGE7114494,A patent/NL175178C/en not_active IP Right Cessation
- 1971-10-21 DK DK513771A patent/DK132174C/en not_active IP Right Cessation
- 1971-10-21 LU LU64129A patent/LU64129A1/xx unknown
- 1971-10-21 IL IL37984A patent/IL37984A/en unknown
- 1971-10-21 CH CH1027775A patent/CH582681A5/xx not_active IP Right Cessation
- 1971-10-21 AT AT909371A patent/AT319948B/en not_active IP Right Cessation
- 1971-10-21 DD DD167435A patent/DD100877A5/xx unknown
- 1971-10-21 CH CH1532171A patent/CH568301A5/xx not_active IP Right Cessation
- 1971-10-21 IE IE1329/71A patent/IE37452B1/en unknown
- 1971-10-21 FI FI2975/71A patent/FI56175C/en active
- 1971-10-21 BE BE774281A patent/BE774281A/en not_active IP Right Cessation
- 1971-10-21 MC MC951A patent/MC894A1/en unknown
- 1971-10-21 JP JP8365271A patent/JPS5536662B1/ja active Pending
- 1971-10-21 IL IL45422A patent/IL45422A/en unknown
- 1971-10-21 BG BG21451A patent/BG20364A3/xx unknown
- 1971-10-21 AR AR238596A patent/AR192588A1/en active
- 1971-10-21 BG BG18828A patent/BG20797A3/xx unknown
- 1971-10-21 CH CH1027675A patent/CH568302A5/xx not_active IP Right Cessation
- 1971-10-21 BG BG21452A patent/BG20365A3/xx not_active Expired
- 1971-10-21 CA CA125,807A patent/CA967158A/en not_active Expired
- 1971-10-21 ES ES396219A patent/ES396219A1/en not_active Expired
- 1971-10-21 ZM ZM149/71A patent/ZM14971A1/en unknown
- 1971-10-21 SE SE7113328A patent/SE384505B/en unknown
- 1971-10-21 FR FR7137870A patent/FR2111769B1/fr not_active Expired
-
1972
- 1972-06-27 AR AR242773A patent/AR192803A1/en active
- 1972-06-27 AR AR242772A patent/AR192802A1/en active
- 1972-10-21 BG BG21466A patent/BG21406A3/xx unknown
-
1974
- 1974-05-20 SE SE7406661A patent/SE409705B/en not_active IP Right Cessation
-
1977
- 1977-12-22 JP JP15499477A patent/JPS53135991A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| BG20797A3 (en) | 1975-12-20 |
| SE409705B (en) | 1979-09-03 |
| NL7114494A (en) | 1972-04-25 |
| DD100877A5 (en) | 1973-10-12 |
| NL175178B (en) | 1984-05-01 |
| BE774281A (en) | 1972-04-21 |
| AR192803A1 (en) | 1973-03-14 |
| IL45422A (en) | 1976-03-31 |
| FI56175C (en) | 1979-12-10 |
| MC894A1 (en) | 1972-06-22 |
| CH582681A5 (en) | 1976-12-15 |
| JPS53135991A (en) | 1978-11-28 |
| GB1375162A (en) | 1974-11-27 |
| DK132174C (en) | 1976-03-29 |
| SE384505B (en) | 1976-05-10 |
| IE37452L (en) | 1972-04-22 |
| CA967158A (en) | 1975-05-06 |
| AR192588A1 (en) | 1973-02-28 |
| ES396219A1 (en) | 1975-09-16 |
| FI56175B (en) | 1979-08-31 |
| BG20365A3 (en) | 1975-11-05 |
| CH568301A5 (en) | 1975-10-31 |
| NL175178C (en) | 1984-10-01 |
| FR2111769B1 (en) | 1974-10-18 |
| JPS5536662B1 (en) | 1980-09-22 |
| IL37984A (en) | 1976-03-31 |
| IE37452B1 (en) | 1977-08-03 |
| FR2111769A1 (en) | 1972-06-09 |
| ZM14971A1 (en) | 1972-07-21 |
| DK132174B (en) | 1975-11-03 |
| CH568302A5 (en) | 1975-10-31 |
| AR192802A1 (en) | 1973-03-14 |
| BG20364A3 (en) | 1975-11-05 |
| LU64129A1 (en) | 1972-06-28 |
| BG21406A3 (en) | 1976-05-20 |
| AT319948B (en) | 1975-01-10 |
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