CA967158A - Benzylpyrimidines - Google Patents

Benzylpyrimidines

Info

Publication number
CA967158A
CA967158A CA125,807A CA125807A CA967158A CA 967158 A CA967158 A CA 967158A CA 125807 A CA125807 A CA 125807A CA 967158 A CA967158 A CA 967158A
Authority
CA
Canada
Prior art keywords
benzylpyrimidines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA125,807A
Other versions
CA125807S (en
Inventor
Thomas Paterson
Alexander Stuart
Barbara Roth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to GB5035070A priority Critical patent/GB1375162A/en
Priority to GB963871 priority
Priority to GB4749171 priority
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Priority claimed from CA205,203A external-priority patent/CA999583A/en
Application granted granted Critical
Publication of CA967158A publication Critical patent/CA967158A/en
Application status is Expired legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulfur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
CA125,807A 1970-10-22 1971-10-21 Benzylpyrimidines Expired CA967158A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GB5035070A GB1375162A (en) 1970-10-22 1970-10-22
GB963871 1971-04-16
GB4749171 1971-10-12

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA205,203A CA999583A (en) 1970-10-22 1974-07-19 Intermediates for benzylpyrimides

Publications (1)

Publication Number Publication Date
CA967158A true CA967158A (en) 1975-05-06

Family

ID=27255400

Family Applications (1)

Application Number Title Priority Date Filing Date
CA125,807A Expired CA967158A (en) 1970-10-22 1971-10-21 Benzylpyrimidines

Country Status (20)

Country Link
JP (2) JPS5536662B1 (en)
AR (3) AR192588A1 (en)
AT (1) AT319948B (en)
BE (1) BE774281A (en)
BG (4) BG20797A3 (en)
CA (1) CA967158A (en)
CH (3) CH568301A5 (en)
DD (1) DD100877A5 (en)
DK (1) DK132174C (en)
ES (1) ES396219A1 (en)
FI (1) FI56175C (en)
FR (1) FR2111769B1 (en)
GB (1) GB1375162A (en)
IE (1) IE37452B1 (en)
IL (2) IL37984A (en)
LU (1) LU64129A1 (en)
MC (1) MC894A1 (en)
NL (1) NL175178C (en)
SE (2) SE384505B (en)
ZM (1) ZM14971A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE792096A (en) * 1971-12-01 1973-05-30 Hoffmann La Roche News benzylpyrimidines
FR2397407B2 (en) * 1977-07-11 1980-01-04 Dick Pierre
NO791699L (en) * 1978-05-24 1979-11-27 Wellcome Found Benzylpyrimidinforbindelser and process for their preparation
JPS61156909A (en) * 1984-12-27 1986-07-16 Matsushita Electric Ind Co Ltd Current mirror circuit
JPS62145907A (en) * 1985-12-20 1987-06-30 Hitachi Ltd Transistor circuit
WO2005092893A1 (en) 2004-03-26 2005-10-06 Dainippon Sumitomo Pharma Co., Ltd. 9-substituted 8-oxoadenine compound
WO2008004948A1 (en) 2006-07-05 2008-01-10 Astrazeneca Ab 8-oxoadenine derivatives acting as modulators of tlr7
TW200831105A (en) 2006-12-14 2008-08-01 Astrazeneca Ab Novel compounds
JP5329444B2 (en) 2007-03-19 2013-10-30 アストラゼネカ・アクチエボラーグAstrazeneca Aktiebolag 9-Substituted-8-oxo-adenine compounds as TOLL-like receptor (TLR7) modulators
DK2132209T3 (en) 2007-03-19 2014-04-14 Astrazeneca Ab 9-substituted 8-oxo adenine compounds as modulators of tlr7 (toll-like receptor 7)
US8044056B2 (en) 2007-03-20 2011-10-25 Dainippon Sumitomo Pharma Co., Ltd. Adenine compound
PE20091236A1 (en) * 2007-11-22 2009-09-16 Astrazeneca Ab Pyrimidine derivatives as immunomodulators TLR7
PE20091156A1 (en) 2007-12-17 2009-09-03 Astrazeneca Ab Salts (3 - {[[3- (6-amino-2-butoxy-8-oxo-7,8-dihydro-9 H -purin-9-yl) propyl] (3-morpholin-4-ylpropyl) amino] methyl} phenyl) acetate
GB0908772D0 (en) 2009-05-21 2009-07-01 Astrazeneca Ab New salts 756
CA2760766A1 (en) 2009-05-21 2010-11-25 Nicholas James Bennett Novel pyrimidine derivatives and their use in the treatment of cancer and further diseases
JP5978225B2 (en) 2010-12-16 2016-08-24 大日本住友製薬株式会社 Imidazo [4,5-c] quinolin-1-yl derivatives useful for therapy
DK2651943T3 (en) 2010-12-17 2017-06-06 Sumitomo Dainippon Pharma Co Ltd purine derivatives
EP2850067B1 (en) 2012-05-18 2017-08-16 Sumitomo Dainippon Pharma Co., Ltd. Carboxylic acid compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE710100A (en) * 1967-02-02 1968-07-30
JPS5331972B2 (en) * 1974-06-25 1978-09-06

Also Published As

Publication number Publication date
BG20364A3 (en) 1975-11-05
ZM14971A1 (en) 1972-07-21
IL37984A (en) 1976-03-31
IL37984D0 (en) 1971-12-29
FR2111769B1 (en) 1974-10-18
AR192802A1 (en) 1973-03-14
BG20797A3 (en) 1975-12-20
CA967158A1 (en)
IL45422A (en) 1976-03-31
JPS53135991A (en) 1978-11-28
DK132174B (en) 1975-11-03
IE37452L (en) 1972-04-22
BG21406A3 (en) 1976-05-20
SE409705B (en) 1979-09-03
SE384505B (en) 1976-05-10
CH568302A5 (en) 1975-10-31
FR2111769A1 (en) 1972-06-09
NL175178B (en) 1984-05-01
BG20365A3 (en) 1975-11-05
LU64129A1 (en) 1972-06-28
BE774281A1 (en)
JPS5536662B1 (en) 1980-09-22
CH582681A5 (en) 1976-12-15
MC894A1 (en) 1972-06-22
CH568301A5 (en) 1975-10-31
DK132174C (en) 1976-03-29
AT319948B (en) 1975-01-10
FI56175C (en) 1979-12-10
GB1375162A (en) 1974-11-27
FI56175B (en) 1979-08-31
DD100877A5 (en) 1973-10-12
ES396219A1 (en) 1975-09-16
AR192588A1 (en) 1973-02-28
BE774281A (en) 1972-04-21
NL7114494A (en) 1972-04-25
AR192803A1 (en) 1973-03-14
IE37452B1 (en) 1977-08-03
NL175178C (en) 1984-10-01

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