AT319948B - Process for the preparation of new 2,4-diamino-5-benzylpyrimidines - Google Patents

Process for the preparation of new 2,4-diamino-5-benzylpyrimidines

Info

Publication number
AT319948B
AT319948B AT909371A AT909371A AT319948B AT 319948 B AT319948 B AT 319948B AT 909371 A AT909371 A AT 909371A AT 909371 A AT909371 A AT 909371A AT 319948 B AT319948 B AT 319948B
Authority
AT
Austria
Prior art keywords
benzylpyrimidines
diamino
preparation
new
Prior art date
Application number
AT909371A
Other languages
German (de)
Inventor
Roth Barbara
Stuart Alexander
Paterson Thomas
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Application granted granted Critical
Publication of AT319948B publication Critical patent/AT319948B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
AT909371A 1970-10-22 1971-10-21 Process for the preparation of new 2,4-diamino-5-benzylpyrimidines AT319948B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB963871*[A GB1375162A (en) 1970-10-22 1970-10-22
GB963871 1971-04-16
GB4749171 1971-10-12

Publications (1)

Publication Number Publication Date
AT319948B true AT319948B (en) 1975-01-10

Family

ID=27255400

Family Applications (1)

Application Number Title Priority Date Filing Date
AT909371A AT319948B (en) 1970-10-22 1971-10-21 Process for the preparation of new 2,4-diamino-5-benzylpyrimidines

Country Status (20)

Country Link
JP (2) JPS5536662B1 (en)
AR (3) AR192588A1 (en)
AT (1) AT319948B (en)
BE (1) BE774281A (en)
BG (4) BG20365A3 (en)
CA (1) CA967158A (en)
CH (3) CH582681A5 (en)
DD (1) DD100877A5 (en)
DK (1) DK132174C (en)
ES (1) ES396219A1 (en)
FI (1) FI56175C (en)
FR (1) FR2111769B1 (en)
GB (1) GB1375162A (en)
IE (1) IE37452B1 (en)
IL (2) IL37984A (en)
LU (1) LU64129A1 (en)
MC (1) MC894A1 (en)
NL (1) NL175178C (en)
SE (2) SE384505B (en)
ZM (1) ZM14971A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE792096A (en) * 1971-12-01 1973-05-30 Hoffmann La Roche NEW BENZYLPYRIMIDINES
FR2397407A2 (en) * 1977-07-11 1979-02-09 Dick Pierre 2,4-DIAMINO PYRIMIDINE DERIVATIVES AND THEIR SOLUTION IN ASSOCIATION WITH SULFAMIDS
IT1117752B (en) * 1978-05-24 1986-02-24 Wellcome Found PHARMACEUTICAL COMPOSITION BASED ON BENZYLPYRIMIDINE AND PROCEDURE FOR ITS PREPARATION
JPS61156909A (en) * 1984-12-27 1986-07-16 Matsushita Electric Ind Co Ltd Current mirror circuit
JPS62145907A (en) * 1985-12-20 1987-06-30 Hitachi Ltd Transistor circuit
US8012964B2 (en) 2004-03-26 2011-09-06 Dainippon Sumitomo Pharma Co., Ltd. 9-substituted 8-oxoadenine compound
EP2041135A4 (en) 2006-07-05 2010-12-01 Astrazeneca Ab 8-oxoadenine derivatives acting as modulators of tlr7
TW200831105A (en) 2006-12-14 2008-08-01 Astrazeneca Ab Novel compounds
US8063051B2 (en) 2007-03-19 2011-11-22 Astrazeneca Ab 9-substituted-8-oxo-adenine compounds as toll-like receptor (TLR7) modulators
SI2132209T1 (en) 2007-03-19 2014-05-30 Astrazeneca Ab 9-substituted-8-oxo-adenine compounds as toll-like receptor (tlr7 ) modulators
JPWO2008114819A1 (en) 2007-03-20 2010-07-08 大日本住友製薬株式会社 New adenine compounds
PE20091236A1 (en) 2007-11-22 2009-09-16 Astrazeneca Ab PYRIMIDINE DERIVATIVES AS IMMUNOMODULATORS OF TLR7
PE20091156A1 (en) 2007-12-17 2009-09-03 Astrazeneca Ab SALTS OF (3 - {[[3- (6-AMINO-2-BUTOXY-8-OXO-7,8-DIHIDRO-9H-PURIN-9-IL) PROPYL] (3-MORFOLIN-4-ILPROPIL) AMINO] METHYL} PHENYL) METHYL ACETATE
SG175796A1 (en) 2009-05-21 2011-12-29 Astrazeneca Ab Novel pyrimidine derivatives and their use in the treatment of cancer and further diseases
GB0908772D0 (en) 2009-05-21 2009-07-01 Astrazeneca Ab New salts 756
JP5978225B2 (en) 2010-12-16 2016-08-24 大日本住友製薬株式会社 Imidazo [4,5-c] quinolin-1-yl derivatives useful for therapy
US8895570B2 (en) 2010-12-17 2014-11-25 Astrazeneca Ab Purine derivatives
WO2013172479A1 (en) 2012-05-18 2013-11-21 Dainippon Sumitomo Pharma Co., Ltd. Carboxylic acid compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE710100A (en) * 1967-02-02 1968-07-30
JPS511716A (en) * 1974-06-25 1976-01-08 Toray Industries HORIESUTERUMARUCHIFUIRAMENTONO SEIHO

Also Published As

Publication number Publication date
ES396219A1 (en) 1975-09-16
BG20364A3 (en) 1975-11-05
DK132174B (en) 1975-11-03
CH568301A5 (en) 1975-10-31
DD100877A5 (en) 1973-10-12
NL175178C (en) 1984-10-01
AR192802A1 (en) 1973-03-14
AR192588A1 (en) 1973-02-28
ZM14971A1 (en) 1972-07-21
FI56175B (en) 1979-08-31
GB1375162A (en) 1974-11-27
IL37984A0 (en) 1971-12-29
IE37452B1 (en) 1977-08-03
BE774281A (en) 1972-04-21
BG20797A3 (en) 1975-12-20
SE384505B (en) 1976-05-10
AR192803A1 (en) 1973-03-14
BG21406A3 (en) 1976-05-20
CH582681A5 (en) 1976-12-15
NL7114494A (en) 1972-04-25
BG20365A3 (en) 1975-11-05
JPS5536662B1 (en) 1980-09-22
MC894A1 (en) 1972-06-22
LU64129A1 (en) 1972-06-28
FR2111769A1 (en) 1972-06-09
DK132174C (en) 1976-03-29
IL45422A (en) 1976-03-31
CH568302A5 (en) 1975-10-31
NL175178B (en) 1984-05-01
JPS53135991A (en) 1978-11-28
IE37452L (en) 1972-04-22
IL37984A (en) 1976-03-31
CA967158A (en) 1975-05-06
SE409705B (en) 1979-09-03
FR2111769B1 (en) 1974-10-18
FI56175C (en) 1979-12-10

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee