CH540925A - Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten - Google Patents

Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten

Info

Publication number
CH540925A
CH540925A CH627569A CH627569A CH540925A CH 540925 A CH540925 A CH 540925A CH 627569 A CH627569 A CH 627569A CH 627569 A CH627569 A CH 627569A CH 540925 A CH540925 A CH 540925A
Authority
CH
Switzerland
Prior art keywords
preparation
new
oxadiazole derivatives
oxadiazole
derivatives
Prior art date
Application number
CH627569A
Other languages
English (en)
Inventor
Kalman Dr Harsanyi
Jozsef Dipl Ing Reiter
Dezso Dipl Ing Korbonits
Casaba Dipl Ing Gonczi
Kalman Dipl Ing Takacs
Erzsebet Dipl Ing Bako
Gyorgy Dr Med Leszkovszky
Tardos Laszlo
Vertesy Csaba
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of CH540925A publication Critical patent/CH540925A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CH627569A 1968-04-26 1969-04-24 Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten CH540925A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUCI000796 1968-04-26

Publications (1)

Publication Number Publication Date
CH540925A true CH540925A (de) 1973-08-31

Family

ID=10994349

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1476972A CH542232A (de) 1968-04-26 1969-04-24 Verfahren zur Herstellung neuer 1,2,4-Oxadiazol-Derivate
CH627569A CH540925A (de) 1968-04-26 1969-04-24 Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH1476972A CH542232A (de) 1968-04-26 1969-04-24 Verfahren zur Herstellung neuer 1,2,4-Oxadiazol-Derivate

Country Status (15)

Country Link
US (1) US3647809A (de)
JP (1) JPS4824394B1 (de)
AT (2) AT292728B (de)
BE (1) BE732131A (de)
BR (1) BR6908381D0 (de)
CA (1) CA954858A (de)
CH (2) CH542232A (de)
DE (1) DE1920037A1 (de)
FR (1) FR2007529B1 (de)
GB (1) GB1271302A (de)
IL (1) IL31990A (de)
NL (1) NL6906401A (de)
NO (1) NO124253B (de)
PL (1) PL79435B1 (de)
SE (1) SE368576B (de)

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* Cited by examiner, † Cited by third party
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US3853893A (en) * 1973-04-02 1974-12-10 Squibb & Sons Inc Anthelmintic 5-(pyridyl)-3-(isothiocyanophenyl) oxadiazoles
HU177086B (en) * 1975-06-09 1981-07-28 Eszakmagyar Vegyimuevek Herbicide and fungicide preparation containing substituted 1,2,4-oxadiazolidin-3-one derivatives
JPS58150576A (ja) * 1982-03-03 1983-09-07 Sumitomo Chem Co Ltd 新規な１，２，４−オキサジアゾ−ル誘導体
DE3247118A1 (de) * 1982-12-20 1984-06-20 Cassella Ag, 6000 Frankfurt Neue substituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
EP1582519A3 (de) * 1999-08-19 2005-12-21 Nps Pharmaceuticals, Inc. Heteropolycyclische verbindungen und ihre verwendung als antagonisten von metabotropen glutamatrezeptoren
ES2250177T3 (es) * 1999-08-19 2006-04-16 Nps Pharmaceuticals, Inc. Compuestos heteropoliciclicos y su uso como antagonistas de receptores de glutamato metabotropico.
US6660753B2 (en) * 1999-08-19 2003-12-09 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
IL157491A0 (en) * 2001-02-21 2004-03-28 Nps Pharmeceuticals Inc Heteropolycyclic compounds and pharmaceutical compositions containing the same
JP2006502134A (ja) * 2002-08-09 2006-01-19 アストラゼネカ アクチボラグ 代謝調節型グルタミン酸受容体において活性を有する化合物
EP1611123B8 (de) * 2003-04-09 2013-11-13 Exelixis, Inc. Tie-2-modulatoren und anwendungsverfahren
EP1625123A4 (de) * 2003-05-15 2007-08-29 Merck & Co Inc 3-(2-amino-1-azacyclyl)-5-aryl-1,2,4-oxadiazole als s1p-rezeptoragonisten
US20060189661A1 (en) * 2003-11-03 2006-08-24 Wagenen Bradford V Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
WO2005060961A2 (en) * 2003-12-18 2005-07-07 Astrazeneca Ab Treatment of transient lower esophageal sphincter relaxations (tlesrs) and gastro-esophageal reflux disease (gerd)
CA2549955A1 (en) * 2003-12-24 2005-07-07 Prosidion Limited Heterocyclic derivatives as gpcr receptor agonists
WO2005077368A2 (en) * 2004-02-03 2005-08-25 Astrazeneca Ab Treatment of gastro-esophageal reflux disease (gerd)
MX2007013263A (es) 2005-04-26 2008-01-22 Neurosearch As Novedosos derivados oxadiazol y su uso medico.
IL169855A (en) * 2005-07-25 2014-05-28 Elta Systems Ltd A system and method for locating a receiver location
KR101370280B1 (ko) 2005-07-26 2014-03-06 바이알 - 포르텔라 앤드 씨에이 에스에이 Ｃｏｍｔ 억제제로서의 니트로카테콜 유도체
EP1845097A1 (de) * 2006-04-10 2007-10-17 Portela & Ca., S.A. Oxadiazolderivate als COMT Inihibitoren
PT2069336E (pt) * 2006-09-07 2013-03-07 Actelion Pharmaceuticals Ltd Derivados de piridin-4-ilo como agentes imunomoduladores
US8288554B2 (en) * 2006-09-08 2012-10-16 Actelion Pharmaceuticals Ltd. Pyridin-3-yl derivatives as immunomodulating agents
HUE031317T2 (hu) * 2007-01-31 2017-07-28 Bial - Portela & Ca S A Specifikus dózisprotokollal adagolt COMT inhibitor nitrokatechin származékok
WO2008114157A1 (en) * 2007-03-16 2008-09-25 Actelion Pharmaceuticals Ltd Amino- pyridine derivatives as s1p1 /edg1 receptor agonists
PL2195311T3 (pl) * 2007-08-17 2011-08-31 Actelion Pharmaceuticals Ltd Pochodne pirydynowe jako modulatory receptora S1P1/EDG1
AU2009217865A1 (en) * 2008-02-28 2009-09-03 Bial - Portela & Ca., S.A. Pharmaceutical composition for poorly soluble drugs
EP2262799B1 (de) * 2008-03-06 2012-07-04 Actelion Pharmaceuticals Ltd. Pyridinverbindungen
ES2414533T3 (es) * 2008-03-07 2013-07-19 Actelion Pharmaceuticals Ltd. Derivados Piridin-2-ilo como agentes inmunomoduladores
AU2009226221A1 (en) 2008-03-17 2009-09-24 Bial - Portela & Ca., S.A. Crystal forms of 5- [3- (2, 5-dichloro-4, 6-dimethyl-1-oxy-pyridine-3-yl) [1,2,3] oxadiazol-5-yl] -3-nit robenzene-1, 2-diol
NZ589617A (en) * 2008-05-14 2012-06-29 Scripps Research Inst 3-(Inden-4-yl)-5-(phenyl)-1,2,4-oxadiazole and 3-(tetralin-5-yl)-5-(phenyl)-1,2,4-oxadiazole derivatives
EP2396321B1 (de) 2009-02-10 2015-05-06 Monsanto Technology LLC Zusammensetzungen und verfahren zur kontrolle von nematoden
KR102329271B1 (ko) * 2009-04-01 2021-11-22 바이알 - 포르텔라 앤드 씨에이 에스에이 니트로카테콜 유도체를 포함하는 제약 제제 및 그의 제조 방법
MX361618B (es) * 2009-04-01 2018-12-13 Bial Portela & Ca Sa Formulaciones farmacéuticas que comprenden derivados de nitrocatecol y métodos para hacer las mismas.
TWI410421B (zh) 2009-07-16 2013-10-01 Actelion Pharmaceuticals Ltd 吡啶－４－基衍生物
AU2012208325B2 (en) 2011-01-19 2016-12-22 Idorsia Pharmaceuticals Ltd 2-methoxy-pyridin-4-yl derivatives
US20140045900A1 (en) 2011-02-11 2014-02-13 Bial-Portela & Ca, S.A. Administration regime for nitrocatechols
PL2791134T3 (pl) 2011-12-13 2020-03-31 BIAL - PORTELA & Cª S.A. Związek chemiczny użyteczny jako związek pośredni do wytwarzania inhibitora katechol-o-metylotransferazy
UA114748C2 (uk) * 2013-02-15 2017-07-25 Монсанто Текнолоджи Ллс 3,5-дизаміщені-4,5-дигідро-1,2,4-оксадіазоли для боротьби з нематодними шкідниками
WO2016083863A1 (en) 2014-11-28 2016-06-02 Bial - Portela & Ca, S.A. Medicaments for slowing parkinson's disease
AU2016263472B2 (en) 2015-05-20 2020-02-27 Idorsia Pharmaceuticals Ltd Crystalline form of the compound (s)-3-{4-[5-(2-cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propane-1,2-diol

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL120029C (de) * 1959-09-29
US3227725A (en) * 1962-04-17 1966-01-04 Union Carbide Corp Certain 3,5-disubstituted 1,2,4-oxadiazole compounds

Also Published As

Publication number Publication date
AT292728B (de) 1971-09-10
NL6906401A (de) 1969-10-28
GB1271302A (en) 1972-04-19
PL79435B1 (en) 1975-06-30
CA954858A (en) 1974-09-17
IL31990A (en) 1974-05-16
NO124253B (de) 1972-03-27
BR6908381D0 (pt) 1973-02-08
BE732131A (de) 1969-10-01
DE1920037A1 (de) 1970-11-12
CH542232A (de) 1973-11-15
FR2007529B1 (de) 1973-03-16
SE368576B (de) 1974-07-08
IL31990A0 (en) 1969-06-25
JPS4824394B1 (de) 1973-07-20
FR2007529A1 (de) 1970-01-09
AT292727B (de) 1971-09-10
US3647809A (en) 1972-03-07

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