CH542232A - Verfahren zur Herstellung neuer 1,2,4-Oxadiazol-Derivate - Google Patents

Verfahren zur Herstellung neuer 1,2,4-Oxadiazol-Derivate

Info

Publication number
CH542232A
CH542232A CH1476972A CH1476972A CH542232A CH 542232 A CH542232 A CH 542232A CH 1476972 A CH1476972 A CH 1476972A CH 1476972 A CH1476972 A CH 1476972A CH 542232 A CH542232 A CH 542232A
Authority
CH
Switzerland
Prior art keywords
preparation
new
oxadiazole derivatives
oxadiazole
derivatives
Prior art date
Application number
CH1476972A
Other languages
English (en)
Inventor
Kalman Dr Harsanyi
Jozsef Dipl Ing Reiter
Dezso Dipl Ing Korbonits
Csaba Dipl Ing Gonczi
Kalman Dipl Ing Takacs
Erzsebet Dipl Ing Bako
Gyorgy Dr Med Leszkovszky
Tardos Laszlo
Vertesy Csaba
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of CH542232A publication Critical patent/CH542232A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D271/00Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/061,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyridine Compounds (AREA)
CH1476972A 1968-04-26 1969-04-24 Verfahren zur Herstellung neuer 1,2,4-Oxadiazol-Derivate CH542232A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUCI000796 1968-04-26

Publications (1)

Publication Number Publication Date
CH542232A true CH542232A (de) 1973-11-15

Family

ID=10994349

Family Applications (2)

Application Number Title Priority Date Filing Date
CH627569A CH540925A (de) 1968-04-26 1969-04-24 Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten
CH1476972A CH542232A (de) 1968-04-26 1969-04-24 Verfahren zur Herstellung neuer 1,2,4-Oxadiazol-Derivate

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH627569A CH540925A (de) 1968-04-26 1969-04-24 Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten

Country Status (15)

Country Link
US (1) US3647809A (de)
JP (1) JPS4824394B1 (de)
AT (2) AT292728B (de)
BE (1) BE732131A (de)
BR (1) BR6908381D0 (de)
CA (1) CA954858A (de)
CH (2) CH540925A (de)
DE (1) DE1920037A1 (de)
FR (1) FR2007529B1 (de)
GB (1) GB1271302A (de)
IL (1) IL31990A (de)
NL (1) NL6906401A (de)
NO (1) NO124253B (de)
PL (1) PL79435B1 (de)
SE (1) SE368576B (de)

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US3853893A (en) * 1973-04-02 1974-12-10 Squibb & Sons Inc Anthelmintic 5-(pyridyl)-3-(isothiocyanophenyl) oxadiazoles
HU177086B (en) * 1975-06-09 1981-07-28 Eszakmagyar Vegyimuevek Herbicide and fungicide preparation containing substituted 1,2,4-oxadiazolidin-3-one derivatives
JPS58150576A (ja) * 1982-03-03 1983-09-07 Sumitomo Chem Co Ltd 新規な1,2,4−オキサジアゾ−ル誘導体
DE3247118A1 (de) * 1982-12-20 1984-06-20 Cassella Ag, 6000 Frankfurt Neue substituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US6660753B2 (en) * 1999-08-19 2003-12-09 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
EP1582519A3 (de) * 1999-08-19 2005-12-21 Nps Pharmaceuticals, Inc. Heteropolycyclische verbindungen und ihre verwendung als antagonisten von metabotropen glutamatrezeptoren
BR0013427A (pt) * 1999-08-19 2002-07-30 Nps Pharma Inc Compostos heteropolicìclicos e seus usos como antagonistas no receptor de glutamato metabotrópico
PL369598A1 (en) * 2001-02-21 2005-05-02 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
AU2003264018A1 (en) 2002-08-09 2004-02-25 Astrazeneca Ab Compounds having an activity at metabotropic glutamate receptors
EP1611123B8 (de) * 2003-04-09 2013-11-13 Exelixis, Inc. Tie-2-modulatoren und anwendungsverfahren
JP2006528980A (ja) * 2003-05-15 2006-12-28 メルク エンド カムパニー インコーポレーテッド S1p受容体作働薬としての3−(2−アミノ−1−アザシクロ)−5−アリール−1,2,4−オキサジアゾール類
US20060189661A1 (en) * 2003-11-03 2006-08-24 Wagenen Bradford V Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
WO2005060961A2 (en) * 2003-12-18 2005-07-07 Astrazeneca Ab Treatment of transient lower esophageal sphincter relaxations (tlesrs) and gastro-esophageal reflux disease (gerd)
WO2005061489A1 (en) * 2003-12-24 2005-07-07 Prosidion Limited Heterocyclic derivatives as gpcr receptor agonists
WO2005077368A2 (en) * 2004-02-03 2005-08-25 Astrazeneca Ab Treatment of gastro-esophageal reflux disease (gerd)
AU2006239418A1 (en) 2005-04-26 2006-11-02 Neurosearch A/S Novel oxadiazole derivatives and their medical use
IL169855A (en) * 2005-07-25 2014-05-28 Elta Systems Ltd A system and method for locating a receiver location
BRPI0613859B8 (pt) 2005-07-26 2021-05-25 Bial Portela & Ca Sa inibidores da comt, seus usos, e composição farmacêutica
EP1845097A1 (de) 2006-04-10 2007-10-17 Portela & Ca., S.A. Oxadiazolderivate als COMT Inihibitoren
MX2009002233A (es) * 2006-09-07 2009-03-16 Actelion Pharmaceuticals Ltd Derivados de piridin-4-il como agentes inmunomoduladores.
EP2069335B1 (de) * 2006-09-08 2012-12-26 Actelion Pharmaceuticals Ltd. Pyridin-3-yl-derivate als immunmodulatoren
EP2124947B1 (de) 2007-01-31 2017-07-19 BIAL - Portela & Ca., S.A. Dosierschema für comt-hemmer
ES2450750T3 (es) * 2007-03-16 2014-03-25 Actelion Pharmaceuticals Ltd. Derivados de amino-piridina como agonistas del receptor S1P1/EDG1
ES2361463T3 (es) * 2007-08-17 2011-06-17 Actelion Pharmaceuticals Ltd. Derivados de piridina como moduladores del receptor s1p1/edg1.
MX2010009043A (es) * 2008-02-28 2010-10-25 Bial Portela & Ca Sa Composicion farmaceutica para farmacos poco solubles.
EP2262799B1 (de) * 2008-03-06 2012-07-04 Actelion Pharmaceuticals Ltd. Pyridinverbindungen
US8575200B2 (en) * 2008-03-07 2013-11-05 Actelion Pharmaceuticals Ltd Pyridin-2-yl derivatives as immunomodulating agents
CA2718772C (en) 2008-03-17 2017-05-02 David Alexander Learmonth Crystal forms of 5-[3-(2,5-dichloro-4,6-dimethyl-1-oxy-pyridine-3-yl)[1,2,4]oxadiazol-5-yl]-3-nit robenzene-1,2-diol
MY156381A (en) * 2008-05-14 2016-02-15 Scripps Research Inst Novel modulators of sphingosine phosphate receptors
WO2010093650A2 (en) 2009-02-10 2010-08-19 Divergence, Inc. Compositions and methods for controlling nematodes
CN105878242A (zh) * 2009-04-01 2016-08-24 巴尔-波特拉及康邦亚股份有限公司 包括硝基儿茶酚衍生物的药物制剂及其制备方法
CN102438595B (zh) * 2009-04-01 2016-04-27 巴尔-波特拉及康邦亚股份有限公司 包括硝基儿茶酚衍生物的药物制剂及其制备方法
AR077413A1 (es) 2009-07-16 2011-08-24 Actelion Pharmaceuticals Ltd Derivados piridin-4-ilo
DK2665720T3 (en) 2011-01-19 2015-07-13 Actelion Pharmaceuticals Ltd 2-methoxy-pyridin-4-yl-yl derivatives
US20140045900A1 (en) 2011-02-11 2014-02-13 Bial-Portela & Ca, S.A. Administration regime for nitrocatechols
PT3604299T (pt) 2011-12-13 2023-10-31 Bial Portela & Ca Sa Composto químico útil como intermediário para a preparação de um inibidor de catecol-o-metiltransferase
UY35327A (es) 2013-02-15 2014-09-30 Monsanto Technology Llc ?4,5-dihidro-1,2,4-oxadiazoles disustituidos en 3,5 y composiciones y métodos para controlar plagas de nematodos?.
WO2016083863A1 (en) 2014-11-28 2016-06-02 Bial - Portela & Ca, S.A. Medicaments for slowing parkinson's disease
HUE047646T2 (hu) 2015-05-20 2020-05-28 Idorsia Pharmaceuticals Ltd Az (S)-3-{4-[5-(2-ciklopentil-6-metoxi-piridin-4-il)-[1,2,4]oxadiazol-3-il]-2-etil-6-metil-fenoxi} -propán-1,2-diol vegyület kristályformája

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL120029C (de) * 1959-09-29
US3227725A (en) * 1962-04-17 1966-01-04 Union Carbide Corp Certain 3,5-disubstituted 1,2,4-oxadiazole compounds

Also Published As

Publication number Publication date
DE1920037A1 (de) 1970-11-12
NL6906401A (de) 1969-10-28
PL79435B1 (en) 1975-06-30
BR6908381D0 (pt) 1973-02-08
BE732131A (de) 1969-10-01
JPS4824394B1 (de) 1973-07-20
GB1271302A (en) 1972-04-19
CH540925A (de) 1973-08-31
AT292727B (de) 1971-09-10
IL31990A (en) 1974-05-16
FR2007529B1 (de) 1973-03-16
US3647809A (en) 1972-03-07
FR2007529A1 (de) 1970-01-09
SE368576B (de) 1974-07-08
AT292728B (de) 1971-09-10
NO124253B (de) 1972-03-27
IL31990A0 (en) 1969-06-25
CA954858A (en) 1974-09-17

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