AT292728B - Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten und deren Säureadditionssalzen und quarternären Salzen - Google Patents
Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten und deren Säureadditionssalzen und quarternären SalzenInfo
- Publication number
- AT292728B AT292728B AT815670A AT815670A AT292728B AT 292728 B AT292728 B AT 292728B AT 815670 A AT815670 A AT 815670A AT 815670 A AT815670 A AT 815670A AT 292728 B AT292728 B AT 292728B
- Authority
- AT
- Austria
- Prior art keywords
- salts
- preparation
- new
- acid addition
- oxadiazole derivatives
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title 2
- 150000005071 1,2,4-oxadiazoles Chemical class 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUCI000796 | 1968-04-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AT292728B true AT292728B (de) | 1971-09-10 |
Family
ID=10994349
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT375469A AT292727B (de) | 1968-04-26 | 1969-04-18 | Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten und deren Säureadditionssalzen und quaternären Salzen |
| AT815670A AT292728B (de) | 1968-04-26 | 1969-04-18 | Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten und deren Säureadditionssalzen und quarternären Salzen |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT375469A AT292727B (de) | 1968-04-26 | 1969-04-18 | Verfahren zur Herstellung von neuen 1,2,4-Oxadiazol-Derivaten und deren Säureadditionssalzen und quaternären Salzen |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US3647809A (de) |
| JP (1) | JPS4824394B1 (de) |
| AT (2) | AT292727B (de) |
| BE (1) | BE732131A (de) |
| BR (1) | BR6908381D0 (de) |
| CA (1) | CA954858A (de) |
| CH (2) | CH540925A (de) |
| DE (1) | DE1920037A1 (de) |
| FR (1) | FR2007529B1 (de) |
| GB (1) | GB1271302A (de) |
| IL (1) | IL31990A (de) |
| NL (1) | NL6906401A (de) |
| NO (1) | NO124253B (de) |
| PL (1) | PL79435B1 (de) |
| SE (1) | SE368576B (de) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3853893A (en) * | 1973-04-02 | 1974-12-10 | Squibb & Sons Inc | Anthelmintic 5-(pyridyl)-3-(isothiocyanophenyl) oxadiazoles |
| HU177086B (en) * | 1975-06-09 | 1981-07-28 | Eszakmagyar Vegyimuevek | Herbicide and fungicide preparation containing substituted 1,2,4-oxadiazolidin-3-one derivatives |
| JPS58150576A (ja) * | 1982-03-03 | 1983-09-07 | Sumitomo Chem Co Ltd | 新規な1,2,4−オキサジアゾ−ル誘導体 |
| DE3247118A1 (de) * | 1982-12-20 | 1984-06-20 | Cassella Ag, 6000 Frankfurt | Neue substituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| CA2381975A1 (en) * | 1999-08-19 | 2001-02-22 | Nps Pharmaceuticals, Inc. | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| US6660753B2 (en) * | 1999-08-19 | 2003-12-09 | Nps Pharmaceuticals, Inc. | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| EP1582519A3 (de) * | 1999-08-19 | 2005-12-21 | Nps Pharmaceuticals, Inc. | Heteropolycyclische verbindungen und ihre verwendung als antagonisten von metabotropen glutamatrezeptoren |
| CA2438991C (en) * | 2001-02-21 | 2010-08-17 | Nps Pharmaceuticals, Inc. | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| MXPA05001590A (es) | 2002-08-09 | 2005-05-23 | Astrazeneca Ab | Compuestos que tienen actividad en los receptores metabotropicos de glutamato. |
| JP4881725B2 (ja) * | 2003-04-09 | 2012-02-22 | エクセリクシス, インク. | Tie−2モジュレータと使用方法 |
| CN1788008A (zh) * | 2003-05-15 | 2006-06-14 | 麦克公司 | 作为s1p受体激动剂的3-(2-氨基-1-氮杂环基)-5-芳基-1,2,4-噁二唑 |
| US20060189661A1 (en) * | 2003-11-03 | 2006-08-24 | Wagenen Bradford V | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| WO2005060961A2 (en) * | 2003-12-18 | 2005-07-07 | Astrazeneca Ab | Treatment of transient lower esophageal sphincter relaxations (tlesrs) and gastro-esophageal reflux disease (gerd) |
| KR101154830B1 (ko) * | 2003-12-24 | 2012-06-18 | 프로시디온 리미티드 | Gpcr 수용체 효능제로서의 헤테로사이클릭 유도체 |
| WO2005077368A2 (en) * | 2004-02-03 | 2005-08-25 | Astrazeneca Ab | Treatment of gastro-esophageal reflux disease (gerd) |
| KR20080000622A (ko) | 2005-04-26 | 2008-01-02 | 뉴로서치 에이/에스 | 신규한 옥사디아졸 유도체 및 이의 의학적 용도 |
| IL169855A (en) * | 2005-07-25 | 2014-05-28 | Elta Systems Ltd | A system and method for locating a receiver location |
| BRPI0613859B8 (pt) | 2005-07-26 | 2021-05-25 | Bial Portela & Ca Sa | inibidores da comt, seus usos, e composição farmacêutica |
| EP1845097A1 (de) * | 2006-04-10 | 2007-10-17 | Portela & Ca., S.A. | Oxadiazolderivate als COMT Inihibitoren |
| KR101470659B1 (ko) * | 2006-09-07 | 2014-12-08 | 액테리온 파마슈티칼 리미티드 | 면역조절제로서 피리딘-4-일 유도체 |
| MX2009002234A (es) * | 2006-09-08 | 2009-03-16 | Actelion Pharmaceuticals Ltd | Derivados de piridin-3-il como agentes inmunomoduladores. |
| SI2481410T1 (sl) | 2007-01-31 | 2017-01-31 | Bial - Portela & Ca., S.A. | Derivati nitrokatehola kot COMT inhibitorji, ki se dajejo s specifičnim dozirnim režimom |
| DK2125797T3 (da) * | 2007-03-16 | 2014-02-10 | Actelion Pharmaceuticals Ltd | Aminopyridinderivater som s1p1/edg1-receptoragonister |
| NZ583957A (en) * | 2007-08-17 | 2011-09-30 | Actelion Pharmaceuticals Ltd | Pyridine derivatives as s1p1/edg1 receptor modulators |
| KR20100126452A (ko) * | 2008-02-28 | 2010-12-01 | 바이알 - 포르텔라 앤드 씨에이 에스에이 | 난용성 약물용 약학적 조성물 |
| CA2714665A1 (en) * | 2008-03-06 | 2009-09-11 | Actelion Pharmaceuticals Ltd | Pyridine compounds |
| JP5435745B2 (ja) * | 2008-03-07 | 2014-03-05 | アクテリオン ファーマシューティカルズ リミテッド | 免疫調節剤としてのピリジン−2−イル誘導体 |
| TW200942531A (en) | 2008-03-17 | 2009-10-16 | Bial Portela & Companhia S A | Crystal forms of a nitrocatechol |
| PL2913326T3 (pl) * | 2008-05-14 | 2020-11-16 | The Scripps Research Institute | Nowe modulatory receptorów fosforanu sfingozyny |
| EP2396321B1 (de) | 2009-02-10 | 2015-05-06 | Monsanto Technology LLC | Zusammensetzungen und verfahren zur kontrolle von nematoden |
| RU2701731C2 (ru) * | 2009-04-01 | 2019-10-01 | Биал-Портела Энд Ка, С.А. | Фармацевтические препараты, содержащие производные нитрокатехина, и способы их получения |
| US20100256194A1 (en) * | 2009-04-01 | 2010-10-07 | Bial - Portela & Ca, S.A. | Pharmaceutical formulations comprising nitrocatechol derivatives and methods of making the same |
| JP5036923B1 (ja) | 2009-07-16 | 2012-09-26 | アクテリオン ファーマシューティカルズ リミテッド | ピリジン−4−イル誘導体 |
| EP2665720B1 (de) | 2011-01-19 | 2015-06-10 | Actelion Pharmaceuticals Ltd. | 2-methoxy-pyridin-4-yl-derivate |
| US20140045900A1 (en) | 2011-02-11 | 2014-02-13 | Bial-Portela & Ca, S.A. | Administration regime for nitrocatechols |
| EP2791134B1 (de) | 2011-12-13 | 2019-09-25 | BIAL - Portela & Cª S.A. | Chemische verbindung als zwischenprodukt zur herstellung eines catechol-o-methyltransferase-inhibitors |
| CN105143214B (zh) * | 2013-02-15 | 2018-04-03 | 孟山都技术公司 | 用于控制线虫害虫的3,5‑二取代的‑4,5‑二氢‑1,2,4‑噁二唑 |
| JP2018500300A (ja) | 2014-11-28 | 2018-01-11 | ノヴィファーマ,エス.アー. | パーキンソン病を遅延させるための医薬 |
| PT3298008T (pt) | 2015-05-20 | 2020-02-03 | Idorsia Pharmaceuticals Ltd | Forma cristalina do composto (s)-3-{4-[5-(2-ciclopentil-6- metoxi-piridin-4-il)-[1,2,4]oxadiazol-3-il]-2-etil-6-metilfenoxi}- propano-1,2¿diol |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL120029C (de) * | 1959-09-29 | |||
| US3227725A (en) * | 1962-04-17 | 1966-01-04 | Union Carbide Corp | Certain 3,5-disubstituted 1,2,4-oxadiazole compounds |
-
1969
- 1969-04-08 US US815520A patent/US3647809A/en not_active Expired - Lifetime
- 1969-04-08 IL IL31990A patent/IL31990A/xx unknown
- 1969-04-14 GB GB09047/69A patent/GB1271302A/en not_active Expired
- 1969-04-18 AT AT375469A patent/AT292727B/de not_active IP Right Cessation
- 1969-04-18 AT AT815670A patent/AT292728B/de not_active IP Right Cessation
- 1969-04-19 DE DE19691920037 patent/DE1920037A1/de active Pending
- 1969-04-24 CH CH627569A patent/CH540925A/de not_active IP Right Cessation
- 1969-04-24 FR FR696912994A patent/FR2007529B1/fr not_active Expired
- 1969-04-24 CH CH1476972A patent/CH542232A/de not_active IP Right Cessation
- 1969-04-25 NL NL6906401A patent/NL6906401A/xx unknown
- 1969-04-25 PL PL1969133199A patent/PL79435B1/pl unknown
- 1969-04-25 BR BR208381/69A patent/BR6908381D0/pt unknown
- 1969-04-25 BE BE732131D patent/BE732131A/xx unknown
- 1969-04-25 SE SE05909/69A patent/SE368576B/xx unknown
- 1969-04-25 NO NO1733/69A patent/NO124253B/no unknown
- 1969-04-25 CA CA049,755A patent/CA954858A/en not_active Expired
- 1969-04-25 JP JP44032259A patent/JPS4824394B1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPS4824394B1 (de) | 1973-07-20 |
| IL31990A (en) | 1974-05-16 |
| BR6908381D0 (pt) | 1973-02-08 |
| FR2007529A1 (de) | 1970-01-09 |
| CH540925A (de) | 1973-08-31 |
| FR2007529B1 (de) | 1973-03-16 |
| IL31990A0 (en) | 1969-06-25 |
| CH542232A (de) | 1973-11-15 |
| NL6906401A (de) | 1969-10-28 |
| GB1271302A (en) | 1972-04-19 |
| AT292727B (de) | 1971-09-10 |
| US3647809A (en) | 1972-03-07 |
| CA954858A (en) | 1974-09-17 |
| NO124253B (de) | 1972-03-27 |
| BE732131A (de) | 1969-10-01 |
| SE368576B (de) | 1974-07-08 |
| DE1920037A1 (de) | 1970-11-12 |
| PL79435B1 (en) | 1975-06-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |