GB1271302A - New pyridyl-oxadiazole derivatives and process for the preparation thereof and pharmaceutical compositions containing same - Google Patents

New pyridyl-oxadiazole derivatives and process for the preparation thereof and pharmaceutical compositions containing same

Info

Publication number
GB1271302A
GB1271302A GB09047/69A GB1904769A GB1271302A GB 1271302 A GB1271302 A GB 1271302A GB 09047/69 A GB09047/69 A GB 09047/69A GB 1904769 A GB1904769 A GB 1904769A GB 1271302 A GB1271302 A GB 1271302A
Authority
GB
United Kingdom
Prior art keywords
compositions
spasmolytic
agents
pharmaceutical compositions
april
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB09047/69A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Publication of GB1271302A publication Critical patent/GB1271302A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D271/00Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/061,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyridine Compounds (AREA)
GB09047/69A 1968-04-26 1969-04-14 New pyridyl-oxadiazole derivatives and process for the preparation thereof and pharmaceutical compositions containing same Expired GB1271302A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUCI000796 1968-04-26

Publications (1)

Publication Number Publication Date
GB1271302A true GB1271302A (en) 1972-04-19

Family

ID=10994349

Family Applications (1)

Application Number Title Priority Date Filing Date
GB09047/69A Expired GB1271302A (en) 1968-04-26 1969-04-14 New pyridyl-oxadiazole derivatives and process for the preparation thereof and pharmaceutical compositions containing same

Country Status (15)

Country Link
US (1) US3647809A (enExample)
JP (1) JPS4824394B1 (enExample)
AT (2) AT292728B (enExample)
BE (1) BE732131A (enExample)
BR (1) BR6908381D0 (enExample)
CA (1) CA954858A (enExample)
CH (2) CH542232A (enExample)
DE (1) DE1920037A1 (enExample)
FR (1) FR2007529B1 (enExample)
GB (1) GB1271302A (enExample)
IL (1) IL31990A (enExample)
NL (1) NL6906401A (enExample)
NO (1) NO124253B (enExample)
PL (1) PL79435B1 (enExample)
SE (1) SE368576B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0116708A1 (de) * 1982-12-20 1984-08-29 CASSELLA Aktiengesellschaft Neue substituierte 1,4-Dihydropyridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
EP0091726A3 (en) * 1982-03-03 1985-05-15 Sumitomo Chemical Company, Limited 5-substituted 1,2,4-oxadiazole derivatives, their preparation and pharmaceutical compositions containing them

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3853893A (en) * 1973-04-02 1974-12-10 Squibb & Sons Inc Anthelmintic 5-(pyridyl)-3-(isothiocyanophenyl) oxadiazoles
HU177086B (en) * 1975-06-09 1981-07-28 Eszakmagyar Vegyimuevek Herbicide and fungicide preparation containing substituted 1,2,4-oxadiazolidin-3-one derivatives
US6660753B2 (en) * 1999-08-19 2003-12-09 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
ATE307129T1 (de) * 1999-08-19 2005-11-15 Nps Pharma Inc Heteropolycyclische verbindungen und ihre verwendung als antagonisten von metabotropen glutamatrezeptoren
EP1582519A3 (en) * 1999-08-19 2005-12-21 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
PL369598A1 (en) * 2001-02-21 2005-05-02 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
US7074809B2 (en) 2002-08-09 2006-07-11 Astrazeneca Ab Compounds
CA2520255C (en) * 2003-04-09 2014-07-08 Exelixis, Inc. Tie-2 modulators and methods of use
WO2004103279A2 (en) * 2003-05-15 2004-12-02 Merck & Co., Inc. 3-(2-amino-1-azacyclyl)-5-aryl-1,2,4-oxadiazoles as s1p receptor agonists
US20060189661A1 (en) * 2003-11-03 2006-08-24 Wagenen Bradford V Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
WO2005060961A2 (en) * 2003-12-18 2005-07-07 Astrazeneca Ab Treatment of transient lower esophageal sphincter relaxations (tlesrs) and gastro-esophageal reflux disease (gerd)
NZ547965A (en) * 2003-12-24 2009-12-24 Prosidion Ltd 1,2,4-Oxadiazole derivatives as GPCR receptor agonists
WO2005077368A2 (en) * 2004-02-03 2005-08-25 Astrazeneca Ab Treatment of gastro-esophageal reflux disease (gerd)
JP2008539195A (ja) * 2005-04-26 2008-11-13 ノイロサーチ アクティーゼルスカブ 新規のオキサジアゾール誘導体及びそれらの医学的使用
IL169855A (en) * 2005-07-25 2014-05-28 Elta Systems Ltd A system and method for locating a receiver location
SI1907382T1 (sl) 2005-07-26 2015-10-30 Bial-Portela & Ca S.A., Nitrokateholni derivati kot inhibitorji COMT
EP1845097A1 (en) * 2006-04-10 2007-10-17 Portela & Ca., S.A. Oxadiazole derivatives as COMT inhibitors
MY149853A (en) * 2006-09-07 2013-10-31 Actelion Pharmaceuticals Ltd Pyridin-4-yl derivatives as immunomodulating agents
AR062684A1 (es) * 2006-09-08 2008-11-26 Actelion Pharmaceuticals Ltd Compuestos derivados de piridin-3- ilo, composicion farmaceutica que los contiene, y uso de los mismos en la preparacion de medicamentos
ES2597705T3 (es) * 2007-01-31 2017-01-20 Bial - Portela & Ca., S.A. Derivados de nitrocatecol como inhibidores de COMT administrados con un régimen de dosificación específico
DK2125797T3 (da) * 2007-03-16 2014-02-10 Actelion Pharmaceuticals Ltd Aminopyridinderivater som s1p1/edg1-receptoragonister
HRP20110449T1 (hr) * 2007-08-17 2011-07-31 Actelion Pharmaceuticals Ltd. Derivati piridina kao modulatori receptora s1p1/edg1
EP2259777A2 (en) * 2008-02-28 2010-12-15 BIAL - Portela & Ca., S.A. Pharmaceutical composition for poorly soluble drugs
CA2714665A1 (en) * 2008-03-06 2009-09-11 Actelion Pharmaceuticals Ltd Pyridine compounds
JP5435745B2 (ja) * 2008-03-07 2014-03-05 アクテリオン ファーマシューティカルズ リミテッド 免疫調節剤としてのピリジン−2−イル誘導体
EP2276758B1 (en) 2008-03-17 2016-01-06 Bial-Portela & CA, S.A. Crystal forms of 5- [3- (2, 5-dichloro-4, 6-dimethyl-1-oxy-pyridine-3-yl) [1,2,4] oxadiazol-5-yl]-3-nit robenzene-1, 2-diol
PL2291080T3 (pl) * 2008-05-14 2015-12-31 Scripps Research Inst Nowe modulatory receptorów sfingozyno-1-fosforanu
ES2754503T3 (es) 2009-02-10 2020-04-17 Monsanto Technology Llc Composiciones y procedimientos de lucha contra nematodos
AU2010231962B2 (en) * 2009-04-01 2015-05-21 Bial - Portela & Ca., S.A. Pharmaceutical formulations comprising nitrocatechol derivatives and methods of making the same
KR102329271B1 (ko) * 2009-04-01 2021-11-22 바이알 - 포르텔라 앤드 씨에이 에스에이 니트로카테콜 유도체를 포함하는 제약 제제 및 그의 제조 방법
KR101409131B1 (ko) 2009-07-16 2014-06-17 액테리온 파마슈티칼 리미티드 피리딘-4-일 유도체
WO2012098505A1 (en) 2011-01-19 2012-07-26 Actelion Pharmaceuticals Ltd 2-methoxy-pyridin-4-yl derivatives
US20140045900A1 (en) 2011-02-11 2014-02-13 Bial-Portela & Ca, S.A. Administration regime for nitrocatechols
PL2791134T3 (pl) 2011-12-13 2020-03-31 BIAL - PORTELA & Cª S.A. Związek chemiczny użyteczny jako związek pośredni do wytwarzania inhibitora katechol-o-metylotransferazy
US9232800B2 (en) * 2013-02-15 2016-01-12 Monsanto Technology Llc 3,5-disubstituted-4,5-dihydro-1,2,4-oxadiazoles and compositions and methods for controlling nematode pests
RU2017120184A (ru) 2014-11-28 2018-12-28 БИАЛ - ПОРТЕЛА ЭНД Ка, С.А. Лекарства для замедления течения болезни паркинсона
EP3298008B1 (en) 2015-05-20 2019-11-20 Idorsia Pharmaceuticals Ltd Crystalline form of the compound (s)-3-{4-[5-(2-cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propane-1,2-diol

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL256329A (enExample) * 1959-09-29
US3227725A (en) * 1962-04-17 1966-01-04 Union Carbide Corp Certain 3,5-disubstituted 1,2,4-oxadiazole compounds

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0091726A3 (en) * 1982-03-03 1985-05-15 Sumitomo Chemical Company, Limited 5-substituted 1,2,4-oxadiazole derivatives, their preparation and pharmaceutical compositions containing them
US4618617A (en) * 1982-03-03 1986-10-21 Sumitomo Chemical Company, Limited Novel 5-substituted 1,2,4,-oxadiazole derivatives and preparation thereof
EP0116708A1 (de) * 1982-12-20 1984-08-29 CASSELLA Aktiengesellschaft Neue substituierte 1,4-Dihydropyridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US4558058A (en) * 1982-12-20 1985-12-10 Cassella Aktiengesellschaft Substituted 1,4-dihydropyridines and their use as medicaments

Also Published As

Publication number Publication date
FR2007529A1 (enExample) 1970-01-09
PL79435B1 (en) 1975-06-30
CH542232A (de) 1973-11-15
US3647809A (en) 1972-03-07
SE368576B (enExample) 1974-07-08
BE732131A (enExample) 1969-10-01
IL31990A0 (en) 1969-06-25
BR6908381D0 (pt) 1973-02-08
NO124253B (enExample) 1972-03-27
DE1920037A1 (de) 1970-11-12
CH540925A (de) 1973-08-31
AT292728B (de) 1971-09-10
IL31990A (en) 1974-05-16
CA954858A (en) 1974-09-17
FR2007529B1 (enExample) 1973-03-16
JPS4824394B1 (enExample) 1973-07-20
AT292727B (de) 1971-09-10
NL6906401A (enExample) 1969-10-28

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