PL377608A1 - Sposób wytwarzania proleków 3'-nukleozydowych - Google Patents

Sposób wytwarzania proleków 3'-nukleozydowych

Info

Publication number
PL377608A1
PL377608A1 PL377608A PL37760803A PL377608A1 PL 377608 A1 PL377608 A1 PL 377608A1 PL 377608 A PL377608 A PL 377608A PL 37760803 A PL37760803 A PL 37760803A PL 377608 A1 PL377608 A1 PL 377608A1
Authority
PL
Poland
Prior art keywords
production
nucleoside prodrugs
nucleoside
prodrugs
Prior art date
Application number
PL377608A
Other languages
English (en)
Polish (pl)
Inventor
Richard Storer
Adel Moussa
Steven Mathieu
Original Assignee
Idenix (Cayman) Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idenix (Cayman) Limited filed Critical Idenix (Cayman) Limited
Publication of PL377608A1 publication Critical patent/PL377608A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PL377608A 2002-12-23 2003-12-23 Sposób wytwarzania proleków 3'-nukleozydowych PL377608A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US43615002P 2002-12-23 2002-12-23

Publications (1)

Publication Number Publication Date
PL377608A1 true PL377608A1 (pl) 2006-02-06

Family

ID=32682350

Family Applications (1)

Application Number Title Priority Date Filing Date
PL377608A PL377608A1 (pl) 2002-12-23 2003-12-23 Sposób wytwarzania proleków 3'-nukleozydowych

Country Status (16)

Country Link
US (1) US20040181051A1 (enExample)
EP (1) EP1575971A4 (enExample)
JP (1) JP2006514038A (enExample)
KR (1) KR20050110611A (enExample)
CN (1) CN100335492C (enExample)
AU (1) AU2003300434A1 (enExample)
BR (1) BR0316868A (enExample)
CA (1) CA2511616A1 (enExample)
IL (1) IL169314A0 (enExample)
MX (1) MXPA05006865A (enExample)
NO (1) NO20053557L (enExample)
NZ (1) NZ540913A (enExample)
PL (1) PL377608A1 (enExample)
RU (1) RU2005123395A (enExample)
WO (1) WO2004058792A1 (enExample)
ZA (1) ZA200505040B (enExample)

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MY164523A (en) 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
CZ301182B6 (cs) 2000-05-26 2009-12-02 Idenix (Cayman) Limited Použití nukleosidových derivátu pro výrobu farmaceutických prostredku pro lécení infekcí vyvolaných flaviviry a pestiviry
NZ537662A (en) 2002-06-28 2007-10-26 Idenix Cayman Ltd 2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
MXPA04012802A (es) 2002-06-28 2005-04-19 Idenix Cayman Ltd Ester 2'-c-metil-3'-o-l-valina de ribofuranosil-citidina para el tratamiento de infecciones por flaviviridae.
WO2004046331A2 (en) 2002-11-15 2004-06-03 Idenix (Cayman) Limited 2’-branched nucleosides and flaviviridae mutation
US7598373B2 (en) 2002-12-12 2009-10-06 Idenix Pharmaceuticals, Inc. Process for the production of 2-C-methyl-D-ribonolactone
CN1812995A (zh) * 2003-04-28 2006-08-02 艾登尼科斯（开曼）有限公司 工业化规模的核苷合成
EP1758453B1 (en) * 2004-06-15 2014-07-16 Merck Sharp & Dohme Corp. C-purine nucleoside analogs as inhibitors of rna-dependent rna viral polymerase
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AU2006222563A1 (en) 2005-03-08 2006-09-14 Biota Scientific Management Pty Ltd. Bicyclic nucleosides and nucleotides as therapeutic agents
EP2537520A1 (en) 2005-03-29 2012-12-26 Biocryst Pharmaceuticals, Inc. Hepatics C therapies
JP4885963B2 (ja) * 2005-09-22 2012-02-29 エフ．ホフマン−ラ ロシュ アーゲー ヌクレオシドの選択的ｏ−アシル化
EP1987050A2 (en) * 2006-02-14 2008-11-05 Merck & Co., Inc. Nucleoside aryl phosphoramidates for the treatment of rna-dependent rna viral infection
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WO2010015637A1 (en) * 2008-08-06 2010-02-11 Novartis Ag New antiviral modified nucleosides
CN102695513A (zh) 2008-12-23 2012-09-26 吉利德制药有限责任公司 核苷氨基磷酸酯
AU2009329917B2 (en) 2008-12-23 2016-03-31 Gilead Pharmasset Llc Nucleoside analogs
BRPI0923815A2 (pt) 2008-12-23 2015-07-14 Pharmasset Inc Síntese de nucleosídeos de purina
JP2012514657A (ja) 2009-01-09 2012-06-28 ユニバーシテイ・カレツジ・オブ・カーデイフ・コンサルタンツ・リミテツド ウィルス感染を治療するためのグアノシンヌクレオシド化合物のホスホルアミダート誘導体
SMT201700412T1 (it) 2010-03-31 2017-11-15 Gilead Pharmasset Llc Procedimento per la cristallizzazione di (s)-isopropil 2-(((s)-(perfluorofenossi)(fenossi)fosforil)ammino)propanoato
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MX2021006121A (es) * 2018-11-25 2021-10-13 Tnt Medical Corp Profarmaco de gemcitabina oralmente activo.

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Also Published As

Publication number Publication date
RU2005123395A (ru) 2006-01-27
CA2511616A1 (en) 2004-07-15
WO2004058792A1 (en) 2004-07-15
EP1575971A4 (en) 2008-03-05
KR20050110611A (ko) 2005-11-23
ZA200505040B (en) 2006-04-26
NO20053557L (no) 2005-09-08
CN1751058A (zh) 2006-03-22
AU2003300434A1 (en) 2004-07-22
CN100335492C (zh) 2007-09-05
MXPA05006865A (es) 2005-12-12
JP2006514038A (ja) 2006-04-27
BR0316868A (pt) 2005-10-25
NZ540913A (en) 2008-02-29
US20040181051A1 (en) 2004-09-16
IL169314A0 (en) 2007-07-04
EP1575971A1 (en) 2005-09-21

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Legal Events

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