PL377608A1 - Sposób wytwarzania proleków 3'-nukleozydowych - Google Patents

Sposób wytwarzania proleków 3'-nukleozydowych

Info

Publication number
PL377608A1
PL377608A1 PL377608A PL37760803A PL377608A1 PL 377608 A1 PL377608 A1 PL 377608A1 PL 377608 A PL377608 A PL 377608A PL 37760803 A PL37760803 A PL 37760803A PL 377608 A1 PL377608 A1 PL 377608A1
Authority
PL
Poland
Prior art keywords
production
nucleoside prodrugs
nucleoside
prodrugs
Prior art date
Application number
PL377608A
Other languages
English (en)
Inventor
Richard Storer
Adel Moussa
Steven Mathieu
Original Assignee
Idenix (Cayman) Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idenix (Cayman) Limited filed Critical Idenix (Cayman) Limited
Publication of PL377608A1 publication Critical patent/PL377608A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PL377608A 2002-12-23 2003-12-23 Sposób wytwarzania proleków 3'-nukleozydowych PL377608A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US43615002P 2002-12-23 2002-12-23

Publications (1)

Publication Number Publication Date
PL377608A1 true PL377608A1 (pl) 2006-02-06

Family

ID=32682350

Family Applications (1)

Application Number Title Priority Date Filing Date
PL377608A PL377608A1 (pl) 2002-12-23 2003-12-23 Sposób wytwarzania proleków 3'-nukleozydowych

Country Status (16)

Country Link
US (1) US20040181051A1 (pl)
EP (1) EP1575971A4 (pl)
JP (1) JP2006514038A (pl)
KR (1) KR20050110611A (pl)
CN (1) CN100335492C (pl)
AU (1) AU2003300434A1 (pl)
BR (1) BR0316868A (pl)
CA (1) CA2511616A1 (pl)
IL (1) IL169314A0 (pl)
MX (1) MXPA05006865A (pl)
NO (1) NO20053557L (pl)
NZ (1) NZ540913A (pl)
PL (1) PL377608A1 (pl)
RU (1) RU2005123395A (pl)
WO (1) WO2004058792A1 (pl)
ZA (1) ZA200505040B (pl)

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AU2003298658A1 (en) 2002-11-15 2004-06-15 Idenix (Cayman) Limited 2'-branched nucleosides and flaviviridae mutation
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JP2008525459A (ja) * 2004-12-23 2008-07-17 ノバルティス アクチエンゲゼルシャフト Ｈｃｖ処置用組成物
US8802840B2 (en) 2005-03-08 2014-08-12 Biota Scientific Management Pty Ltd. Bicyclic nucleosides and nucleotides as therapeutic agents
US7514410B2 (en) 2005-03-29 2009-04-07 Biocryst Pharmaceuticals, Inc. Hepatitis C therapies
AU2006298891A1 (en) * 2005-09-22 2007-04-12 F. Hoffmann-La Roche Ag Selective O-acylation of nucleosides
US7879815B2 (en) * 2006-02-14 2011-02-01 Merck Sharp & Dohme Corp. Nucleoside aryl phosphoramidates for the treatment of RNA-dependent RNA viral infection
WO2007113159A1 (en) 2006-04-04 2007-10-11 F. Hoffmann-La Roche Ag 3',5'-di-o-acylated nucleosides for hcv treatment
WO2010015637A1 (en) * 2008-08-06 2010-02-11 Novartis Ag New antiviral modified nucleosides
MX2011006890A (es) 2008-12-23 2011-07-20 Pharmasset Inc Analogos de nucleosidos.
JP5793084B2 (ja) 2008-12-23 2015-10-14 ギリアド ファーマセット エルエルシー プリンヌクレオシドの合成
TW201026715A (en) 2008-12-23 2010-07-16 Pharmasset Inc Nucleoside phosphoramidates
JP2012514657A (ja) * 2009-01-09 2012-06-28 ユニバーシテイ・カレツジ・オブ・カーデイフ・コンサルタンツ・リミテツド ウィルス感染を治療するためのグアノシンヌクレオシド化合物のホスホルアミダート誘導体
PT2552930E (pt) 2010-03-31 2015-11-17 Gilead Pharmasset Llc 2-(((s)-(((2r,3r,4r,5r)-5-(2,4-dioxo-3,4-dihidropirimidin- 1-(2h)-il)-4-fluoro-3-hidroxi-4-metiltetrahidrofuran-2- il)metoxi) (fenoxi)fosforil)amino)propanoato de (s)- isopropilo cristalino
JP2019526596A (ja) 2016-09-07 2019-09-19 アテア ファーマシューティカルズ， インコーポレイテッド Ｒｎａウイルス治療に対する２’−置換−ｎ６−置換プリンヌクレオチド
AU2019384826A1 (en) * 2018-11-25 2021-07-15 Tnt Medical Corporation Orally active prodrug of gemcitabine

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Also Published As

Publication number Publication date
MXPA05006865A (es) 2005-12-12
WO2004058792A1 (en) 2004-07-15
US20040181051A1 (en) 2004-09-16
AU2003300434A1 (en) 2004-07-22
RU2005123395A (ru) 2006-01-27
CN100335492C (zh) 2007-09-05
ZA200505040B (en) 2006-04-26
IL169314A0 (en) 2007-07-04
NO20053557L (no) 2005-09-08
JP2006514038A (ja) 2006-04-27
NZ540913A (en) 2008-02-29
BR0316868A (pt) 2005-10-25
KR20050110611A (ko) 2005-11-23
CN1751058A (zh) 2006-03-22
CA2511616A1 (en) 2004-07-15
EP1575971A4 (en) 2008-03-05
EP1575971A1 (en) 2005-09-21

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Legal Events

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REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)