PL377291A1 - Wytwarzanie IL-21 w gospodarzach prokariotycznych - Google Patents

Wytwarzanie IL-21 w gospodarzach prokariotycznych

Info

Publication number
PL377291A1
PL377291A1 PL377291A PL37729103A PL377291A1 PL 377291 A1 PL377291 A1 PL 377291A1 PL 377291 A PL377291 A PL 377291A PL 37729103 A PL37729103 A PL 37729103A PL 377291 A1 PL377291 A1 PL 377291A1
Authority
PL
Poland
Prior art keywords
coli
production
expression
vectors
prokaryotic hosts
Prior art date
Application number
PL377291A
Other languages
English (en)
Other versions
PL209009B1 (pl
Inventor
Douglas C. Covert
Chung Chang
Bruce L. Zamost
Hong Y. Liu
Jongh Karen S. De
Jeffrey D. Meyer
Susan D. Holderman
Original Assignee
Zymogenetics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics, Inc. filed Critical Zymogenetics, Inc.
Publication of PL377291A1 publication Critical patent/PL377291A1/pl
Publication of PL209009B1 publication Critical patent/PL209009B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
PL377291A 2002-12-13 2003-12-12 Wektor ekspresyjny do otrzymywania białka IL-21, komórka prokariotycznego gospodarza i sposób otrzymywania białek PL209009B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43345202P 2002-12-13 2002-12-13
US43344802P 2002-12-13 2002-12-13

Publications (2)

Publication Number Publication Date
PL377291A1 true PL377291A1 (pl) 2006-01-23
PL209009B1 PL209009B1 (pl) 2011-07-29

Family

ID=32600150

Family Applications (1)

Application Number Title Priority Date Filing Date
PL377291A PL209009B1 (pl) 2002-12-13 2003-12-12 Wektor ekspresyjny do otrzymywania białka IL-21, komórka prokariotycznego gospodarza i sposób otrzymywania białek

Country Status (17)

Country Link
US (4) US7250274B2 (pl)
EP (1) EP1573006B1 (pl)
JP (1) JP4664684B2 (pl)
KR (1) KR101098897B1 (pl)
AT (1) ATE448298T1 (pl)
AU (1) AU2003302250B2 (pl)
BR (1) BR0317243A (pl)
CA (1) CA2507817C (pl)
DE (1) DE60330044D1 (pl)
DK (1) DK1573006T3 (pl)
ES (1) ES2334127T3 (pl)
IL (2) IL168697A (pl)
MX (1) MXPA05006117A (pl)
NO (1) NO334561B1 (pl)
PL (1) PL209009B1 (pl)
RU (1) RU2354703C2 (pl)
WO (1) WO2004055168A2 (pl)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6307024B1 (en) * 1999-03-09 2001-10-23 Zymogenetics, Inc. Cytokine zalpha11 Ligand
CA2529520A1 (en) * 2003-06-19 2004-12-29 Centocor, Inc. Interleukin-21 analogs
EP2263684A1 (en) 2003-10-10 2010-12-22 Novo Nordisk A/S IL-21 derivatives
US20060228331A1 (en) 2003-10-10 2006-10-12 Novo Nordisk A/S IL-21 Derivatives and variants
ES2428358T3 (es) 2003-10-17 2013-11-07 Novo Nordisk A/S Terapia de combinación
WO2005113001A1 (en) * 2004-05-20 2005-12-01 Zymogenetics, Inc. Methods of treating cancer using il-21 and monoclonal antibody therapy
MX2007012887A (es) 2005-04-18 2007-12-10 Novo Nordisk As Variantes il-21.
ATE515566T1 (de) * 2005-05-26 2011-07-15 Cytos Biotechnology Ag Skalierbares fermentationsverfahren
JP2008542430A (ja) * 2005-06-06 2008-11-27 ノボ・ノルデイスク・エー／エス 安定化ｉｌ−２１組成物
WO2007025987A1 (en) 2005-08-30 2007-03-08 Novo Nordisk A/S Expression of proteins in e.coli
CA2620338A1 (en) 2005-09-22 2007-04-12 Inserm (Institut De La Sante Et De La Recherche Medicale) Methods of using il-21
DK1931704T3 (da) * 2005-10-04 2011-03-14 Zymogenetics L L C Frembringelse og rensning af IL-29
EP2805971A1 (en) * 2005-11-28 2014-11-26 ZymoGenetics, Inc. IL-21 antagonists
EP1966232A1 (en) * 2005-12-23 2008-09-10 Novo Nordisk A/S Purification of proteins using preparative reverse phase chromatography (rpc)
SG174013A1 (en) * 2006-07-27 2011-09-29 Wyeth Corp High-cell density fed-batch fermentation process for producing recombinant protein
WO2008049920A2 (en) 2006-10-26 2008-05-02 Novo Nordisk A/S Il-21 variants
WO2008074863A1 (en) 2006-12-21 2008-06-26 Novo Nordisk A/S Interleukin-21 variants with altered binding to the il-21 receptor
WO2008104513A1 (en) * 2007-03-01 2008-09-04 Novo Nordisk A/S Expression of proteins in e. coli
JP5358840B2 (ja) * 2007-11-24 2013-12-04 独立行政法人産業技術総合研究所 Ｇｆｐ（緑色蛍光蛋白質）の機能賦活・回復方法
EP3103813A1 (en) 2007-12-07 2016-12-14 ZymoGenetics, Inc. Anti-human il-21 monoclonal antibodies
US9927440B2 (en) * 2009-11-25 2018-03-27 Duke University Protein engineering
WO2011149917A1 (en) * 2010-05-25 2011-12-01 Adlyfe, Inc. STABILIZED AMYLOID- β OLIGOMERS AND USES THEREOF
WO2013169693A1 (en) 2012-05-09 2013-11-14 Bristol-Myers Squibb Company Methods of treating cancer using an il-21 polypeptide and an anti-pd-1 antibody
JP6086378B2 (ja) * 2012-11-30 2017-03-01 国立大学法人お茶の水女子大学 組み換えヒト膵臓リパーゼの調製方法
WO2015178466A1 (ja) * 2014-05-21 2015-11-26 味の素株式会社 フィブロイン様タンパク質の製造法
RU2620073C2 (ru) * 2015-06-02 2017-05-22 Федеральное государственное бюджетное учреждение "Государственный научный центр Институт иммунологии" Федерального медико-биологического агентства России Оптимизированный ген, кодирующий рекомбинантный белок - аналог интерферона альфа-17 человека
RU2614264C2 (ru) * 2015-06-19 2017-03-24 Федеральное государственное бюджетное учреждение "Государственный научный центр Институт иммунологии" Федерального медико-биологического агентства России Оптимизированный ген, кодирующий рекомбинантный белок - аналог интерферона бета человека
RU2614124C9 (ru) * 2015-10-01 2020-04-22 Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства России (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) Оптимизированный ген, кодирующий рекомбинантный белок ипфiii
WO2017104759A1 (ja) * 2015-12-16 2017-06-22 株式会社 資生堂 タブレット型凍結乾燥化粧料
JP6404405B1 (ja) * 2017-06-14 2018-10-10 株式会社 資生堂 タブレット型凍結乾燥化粧料
US20210145705A1 (en) * 2017-06-19 2021-05-20 Shiseido Company, Ltd. Tablet-type freeze-dried cosmetic
US20240076704A1 (en) * 2019-10-14 2024-03-07 Inbiose N.V. Production of bioproduct in a host cell
AU2021286574A1 (en) * 2020-06-09 2023-01-19 Icosavax, Inc. Method of making virus-like particle

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001501619A (ja) * 1996-10-04 2001-02-06 アムジェン インコーポレーテッド ｍｐｌリガンドを含有する医薬組成物
US6057128A (en) * 1998-03-17 2000-05-02 Genetics Institute, Inc. MU-1, member of the cytokine receptor family
US6307024B1 (en) * 1999-03-09 2001-10-23 Zymogenetics, Inc. Cytokine zalpha11 Ligand
DK1165791T3 (da) * 1999-03-09 2008-02-11 Zymogenetics Inc Humant cytokin som zalpha-receptor-ligand og anvendelse deraf
US6812339B1 (en) * 2000-09-08 2004-11-02 Applera Corporation Polymorphisms in known genes associated with human disease, methods of detection and uses thereof
US20050063947A1 (en) 2002-03-27 2005-03-24 Patrick Hwu Method for treating cancer in humans
WO2003087320A2 (en) 2002-04-09 2003-10-23 Beth Israel Deaconess Medical Center, Inc. Antagonists of il-21 and modulation of il-21-mediated t cell responses
JP2006525223A (ja) 2002-10-11 2006-11-09 ノボ・ノルデイスク・エー／エス Ｉｌ２１の使用によるアレルギー症状の治療
CN1513993A (zh) 2002-12-31 2004-07-21 北京博泰迪生物工程科技开发有限公司 中国人基因组cDNA文库白细胞介素21的编码基因序列及其蛋白质的氨基酸序列
CA2529520A1 (en) * 2003-06-19 2004-12-29 Centocor, Inc. Interleukin-21 analogs
MXPA06005837A (es) 2003-11-24 2007-01-26 Novo Nordisk As Proteinas de fusion y metodos de desdoblamiento de tales proteinas.

Also Published As

Publication number Publication date
IL168697A (en) 2011-10-31
JP2006509525A (ja) 2006-03-23
MXPA05006117A (es) 2005-09-30
US7622561B2 (en) 2009-11-24
IL198074A0 (en) 2011-08-01
EP1573006A4 (en) 2006-06-14
NO334561B1 (no) 2014-04-07
DK1573006T3 (da) 2010-03-22
US7250274B2 (en) 2007-07-31
ATE448298T1 (de) 2009-11-15
KR101098897B1 (ko) 2011-12-26
NO20053385L (no) 2005-07-12
ES2334127T3 (es) 2010-03-05
EP1573006A2 (en) 2005-09-14
BR0317243A (pt) 2005-11-01
AU2003302250B2 (en) 2009-08-27
JP4664684B2 (ja) 2011-04-06
WO2004055168A2 (en) 2004-07-01
RU2354703C2 (ru) 2009-05-10
US7767199B2 (en) 2010-08-03
CA2507817A1 (en) 2004-07-01
WO2004055168A3 (en) 2005-06-02
EP1573006B1 (en) 2009-11-11
US20070048263A1 (en) 2007-03-01
AU2003302250A1 (en) 2004-07-09
US20060134754A1 (en) 2006-06-22
US20070048798A1 (en) 2007-03-01
US7745176B2 (en) 2010-06-29
PL209009B1 (pl) 2011-07-29
US20070048842A1 (en) 2007-03-01
RU2005117338A (ru) 2006-03-20
KR20050090393A (ko) 2005-09-13
DE60330044D1 (de) 2009-12-24
CA2507817C (en) 2014-04-22

Similar Documents

Publication Publication Date Title
IL198074A0 (en) Il-21 production in prokaryotic hosts
SI1828239T1 (sl) Proizvodnja fgf18 v prokariotskih gostiteljih
Wu et al. CAMERS‐B: CRISPR/Cpf1 assisted multiple‐genes editing and regulation system for Bacillus subtilis
MY207355A (en) Codon-optimized acid lpha-glucosidase expression cassettes and methods of using same
AU2002311989A1 (en) Methods and materials for the production of organic products in cells of $i(candida) species
AU3246300A (en) Polypeptides having galactose oxidase activity and nucleic acids encoding same
ES8607388A1 (es) Un metodo para preparar que tiene sustancialmente la misma secuencia de aminoacidos que la superoxido-dismutasa humana.
CN104059872A (zh) 高产n-乙酰氨基葡萄糖代谢工程菌及其构建方法和应用
WO2019136618A1 (zh) 高产尿苷的基因工程菌及其构建方法与应用
CN104894077B (zh) 烟酰胺腺嘌呤二核苷酸-细胞色素p450还原酶及其应用
DK1792982T3 (da) Codon-optimeret phosphatase og ekspression heraf i gær
CN103865944B (zh) 一种生产核黄素的大肠杆菌菌株及构建方法及用途
CN108330136A (zh) 一种构建产黄素单核苷酸的工程菌株的方法及其应用
MX2021000201A (es) Sistema y métodos para modificar bacterias adecuadas para la producción, exportación y traducción de arnm eucariota en un hospedador eucariota.
Wang et al. CRISPR‐Cas9 mediated genome editing of Kluyveromyces marxianus for iterative, multiplexed gene disruption and pathway integration
WO2004018630A3 (en) Recombinant double-stranded rna phages and uses thereof
WO1994000463A3 (en) Production of hyaluronic acid by transeformed microorganisms
Pilon et al. Ubiquitin fusion technology: bioprocessing of peptides
Chen et al. Streptomyces aureorectus DSM 41692 and Streptomyces virens DSM 41465 are producers of the antibiotic nucleocidin and 4′-fluoroadenosine is identified as a co-product
AU2002224554A1 (en) Cytochrome b5 gene and protein of candida tropicalis and methods relating thereto
EP0465132A2 (en) DNA and its use
AU2002314183A1 (en) Method of plasmid stabilisation by in vivo deleting the antibiotic resistence and selecting with an essential gene
AU4302000A (en) Genome sequence and polypeptides of pyrococcus (abissy), fragment and uses thereof
CN1814761B (zh) 吡咯喹啉醌合成相关基因及其编码蛋白
EP1844135B1 (en) Escherichia strain capable of converting xmp to gmp and maintaining the inactivated state of gene(s) associated with gmp degradation and methods of using the same

Legal Events

Date Code Title Description
RECP Rectifications of patent specification