PL377291A1 - Wytwarzanie IL-21 w gospodarzach prokariotycznych - Google Patents

Wytwarzanie IL-21 w gospodarzach prokariotycznych

Info

Publication number
PL377291A1
PL377291A1 PL377291A PL37729103A PL377291A1 PL 377291 A1 PL377291 A1 PL 377291A1 PL 377291 A PL377291 A PL 377291A PL 37729103 A PL37729103 A PL 37729103A PL 377291 A1 PL377291 A1 PL 377291A1
Authority
PL
Poland
Prior art keywords
coli
production
expression
vectors
prokaryotic hosts
Prior art date
Application number
PL377291A
Other languages
English (en)
Other versions
PL209009B1 (pl
Inventor
Douglas C. Covert
Chung Chang
Bruce L. Zamost
Hong Y. Liu
Jongh Karen S. De
Jeffrey D. Meyer
Susan D. Holderman
Original Assignee
Zymogenetics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics, Inc. filed Critical Zymogenetics, Inc.
Publication of PL377291A1 publication Critical patent/PL377291A1/pl
Publication of PL209009B1 publication Critical patent/PL209009B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
PL377291A 2002-12-13 2003-12-12 Wektor ekspresyjny do otrzymywania białka IL-21, komórka prokariotycznego gospodarza i sposób otrzymywania białek PL209009B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43345202P 2002-12-13 2002-12-13
US43344802P 2002-12-13 2002-12-13

Publications (2)

Publication Number Publication Date
PL377291A1 true PL377291A1 (pl) 2006-01-23
PL209009B1 PL209009B1 (pl) 2011-07-29

Family

ID=32600150

Family Applications (1)

Application Number Title Priority Date Filing Date
PL377291A PL209009B1 (pl) 2002-12-13 2003-12-12 Wektor ekspresyjny do otrzymywania białka IL-21, komórka prokariotycznego gospodarza i sposób otrzymywania białek

Country Status (17)

Country Link
US (4) US7250274B2 (pl)
EP (1) EP1573006B1 (pl)
JP (1) JP4664684B2 (pl)
KR (1) KR101098897B1 (pl)
AT (1) ATE448298T1 (pl)
AU (1) AU2003302250B2 (pl)
BR (1) BR0317243A (pl)
CA (1) CA2507817C (pl)
DE (1) DE60330044D1 (pl)
DK (1) DK1573006T3 (pl)
ES (1) ES2334127T3 (pl)
IL (2) IL168697A (pl)
MX (1) MXPA05006117A (pl)
NO (1) NO334561B1 (pl)
PL (1) PL209009B1 (pl)
RU (1) RU2354703C2 (pl)
WO (1) WO2004055168A2 (pl)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6307024B1 (en) 1999-03-09 2001-10-23 Zymogenetics, Inc. Cytokine zalpha11 Ligand
EP1641422A4 (en) * 2003-06-19 2007-08-22 Centocor Inc ANALOGUES OF INTERLEUKINE-21
US20060228331A1 (en) 2003-10-10 2006-10-12 Novo Nordisk A/S IL-21 Derivatives and variants
WO2005035565A1 (en) * 2003-10-10 2005-04-21 Novo Nordisk A/S Il-21 derivatives
EP2633866A3 (en) 2003-10-17 2013-12-18 Novo Nordisk A/S Combination therapy
CA2566745A1 (en) * 2004-05-20 2005-12-01 Zymogenetics, Inc. Methods of treating cancer using il-21 and monoclonal antibody therapy
WO2006111524A2 (en) 2005-04-18 2006-10-26 Novo Nordisk A/S Il-21 variants
CA2608579C (en) * 2005-05-26 2019-09-10 Cytos Biotechnology Ag Scalable fermentation process
RU2420308C2 (ru) * 2005-06-06 2011-06-10 Ново Нордикс А/С Стабилизированные композиции ил-21
ATE529441T1 (de) 2005-08-30 2011-11-15 Novo Nordisk As Expression von proteinen in e.coli
WO2007039147A1 (en) 2005-09-22 2007-04-12 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods of using il-21
ES2357152T3 (es) * 2005-10-04 2011-04-19 Zymogenetics, L.L.C. Producción y purificación de il-29.
PT1963369E (pt) * 2005-11-28 2013-05-28 Zymogenetics Inc Antagonistas de il-21
JP5401097B2 (ja) * 2005-12-23 2014-01-29 ノボ・ノルデイスク・エー/エス 分取逆相クロマトグラフィー(rpc)を使用するタンパク質精製
DK2061897T3 (da) 2006-07-27 2020-06-02 Wyeth Llc Fed-batch-fermenteringsproces med høj celledensitet til fremstilling af rekombinant protein
AU2007310777A1 (en) 2006-10-26 2008-05-02 Novo Nordisk A/S IL-21 variants
EP2109620B1 (en) * 2006-12-21 2012-08-22 Novo Nordisk A/S Interleukin-21 variants with altered binding to the il-21 receptor
CN101622269A (zh) * 2007-03-01 2010-01-06 诺沃-诺迪斯克有限公司 蛋白质在大肠杆菌中的表达
JP5358840B2 (ja) * 2007-11-24 2013-12-04 独立行政法人産業技術総合研究所 Gfp(緑色蛍光蛋白質)の機能賦活・回復方法
ES2572231T3 (es) 2007-12-07 2016-05-30 Zymogenetics Inc Anticuerpos monoclonales anti-IL-21 humana
US9927440B2 (en) * 2009-11-25 2018-03-27 Duke University Protein engineering
WO2011149917A1 (en) * 2010-05-25 2011-12-01 Adlyfe, Inc. STABILIZED AMYLOID- β OLIGOMERS AND USES THEREOF
WO2013169693A1 (en) 2012-05-09 2013-11-14 Bristol-Myers Squibb Company Methods of treating cancer using an il-21 polypeptide and an anti-pd-1 antibody
JP6086378B2 (ja) * 2012-11-30 2017-03-01 国立大学法人お茶の水女子大学 組み換えヒト膵臓リパーゼの調製方法
JPWO2015178466A1 (ja) * 2014-05-21 2017-04-20 味の素株式会社 フィブロイン様タンパク質の製造法
RU2620073C2 (ru) * 2015-06-02 2017-05-22 Федеральное государственное бюджетное учреждение "Государственный научный центр Институт иммунологии" Федерального медико-биологического агентства России Оптимизированный ген, кодирующий рекомбинантный белок - аналог интерферона альфа-17 человека
RU2614264C2 (ru) * 2015-06-19 2017-03-24 Федеральное государственное бюджетное учреждение "Государственный научный центр Институт иммунологии" Федерального медико-биологического агентства России Оптимизированный ген, кодирующий рекомбинантный белок - аналог интерферона бета человека
RU2614124C9 (ru) * 2015-10-01 2020-04-22 Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства России (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) Оптимизированный ген, кодирующий рекомбинантный белок ипфiii
JP2017110001A (ja) * 2015-12-16 2017-06-22 株式会社 資生堂 タブレット型凍結乾燥化粧料
JP6404405B1 (ja) * 2017-06-14 2018-10-10 株式会社 資生堂 タブレット型凍結乾燥化粧料
EP3643294B1 (en) * 2017-06-19 2023-11-29 Shiseido Company, Ltd. Tablet-type freeze-dried cosmetic
JP2022551195A (ja) * 2019-10-14 2022-12-07 インバイオス エン.フェー. 宿主細胞におけるバイオプロダクトの産生
CA3182002A1 (en) * 2020-06-09 2021-12-16 Charles Richardson Method of making virus-like particle

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1142940C (zh) * 1996-10-04 2004-03-24 安姆根有限公司 含有mpl配体的药物组合物
US6057128A (en) 1998-03-17 2000-05-02 Genetics Institute, Inc. MU-1, member of the cytokine receptor family
US6307024B1 (en) 1999-03-09 2001-10-23 Zymogenetics, Inc. Cytokine zalpha11 Ligand
CA2366921C (en) * 1999-03-09 2013-12-17 Zymogenetics, Inc. Novel cytokine zalpha11 ligand
US6812339B1 (en) * 2000-09-08 2004-11-02 Applera Corporation Polymorphisms in known genes associated with human disease, methods of detection and uses thereof
WO2003082212A2 (en) 2002-03-27 2003-10-09 The Governement Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Method for treating cancer in humans
AU2003230834A1 (en) 2002-04-09 2003-10-27 Beth Israel Deaconess Medical Center, Inc. Antagonists of il-21 and modulation of il-21-mediated t cell responses
MXPA05003729A (es) 2002-10-11 2005-06-17 Novo Nordisk As Tratamiento de condiciones alergicas mediante el uso de il 21.
CN1513993A (zh) 2002-12-31 2004-07-21 北京博泰迪生物工程科技开发有限公司 中国人基因组cDNA文库白细胞介素21的编码基因序列及其蛋白质的氨基酸序列
EP1641422A4 (en) 2003-06-19 2007-08-22 Centocor Inc ANALOGUES OF INTERLEUKINE-21
JP2007512008A (ja) 2003-11-24 2007-05-17 ノボ ノルディスク アクティーゼルスカブ 融合タンパク質及び該タンパク質の切断方法

Also Published As

Publication number Publication date
ES2334127T3 (es) 2010-03-05
AU2003302250A1 (en) 2004-07-09
JP2006509525A (ja) 2006-03-23
EP1573006A2 (en) 2005-09-14
CA2507817C (en) 2014-04-22
IL168697A (en) 2011-10-31
WO2004055168A2 (en) 2004-07-01
US20070048842A1 (en) 2007-03-01
US7745176B2 (en) 2010-06-29
PL209009B1 (pl) 2011-07-29
WO2004055168A3 (en) 2005-06-02
US20070048798A1 (en) 2007-03-01
JP4664684B2 (ja) 2011-04-06
MXPA05006117A (es) 2005-09-30
BR0317243A (pt) 2005-11-01
KR20050090393A (ko) 2005-09-13
EP1573006B1 (en) 2009-11-11
RU2005117338A (ru) 2006-03-20
US20060134754A1 (en) 2006-06-22
DE60330044D1 (de) 2009-12-24
EP1573006A4 (en) 2006-06-14
NO334561B1 (no) 2014-04-07
KR101098897B1 (ko) 2011-12-26
DK1573006T3 (da) 2010-03-22
US20070048263A1 (en) 2007-03-01
IL198074A0 (en) 2011-08-01
AU2003302250B2 (en) 2009-08-27
RU2354703C2 (ru) 2009-05-10
NO20053385L (no) 2005-07-12
US7767199B2 (en) 2010-08-03
US7250274B2 (en) 2007-07-31
US7622561B2 (en) 2009-11-24
CA2507817A1 (en) 2004-07-01
ATE448298T1 (de) 2009-11-15

Similar Documents

Publication Publication Date Title
IL198074A0 (en) Il-21 production in prokaryotic hosts
HK1113161A1 (en) Fgf18 production in prokaryotic hosts
Wu et al. CAMERS‐B: CRISPR/Cpf1 assisted multiple‐genes editing and regulation system for Bacillus subtilis
CN106795209B (zh) 重组四环素外排泵用于生产赖氨酸或赖氨酸衍生产物
AU3246300A (en) Polypeptides having galactose oxidase activity and nucleic acids encoding same
ES8607388A1 (es) Un metodo para preparar que tiene sustancialmente la misma secuencia de aminoacidos que la superoxido-dismutasa humana.
WO2019136618A1 (zh) 高产尿苷的基因工程菌及其构建方法与应用
MX2020012332A (es) Casetes de expresion de alfa-glucosidasa de acido optimizado con codon y metodos de uso del mismo.
PH12020552291A1 (en) System and methods for engineering bacteria fit for eukaryotic mrna production, export, and translation in a eukaryotic host
EP1194575A4 (en) MODIFIED HUMAN GRANULOCYTE COLONY, STIMULATING FACTOR, AND METHOD FOR PRODUCING THE SAME
WO2004018630A3 (en) Recombinant double-stranded rna phages and uses thereof
WO1994000463A3 (en) Production of hyaluronic acid by transeformed microorganisms
Pilon et al. Ubiquitin fusion technology: bioprocessing of peptides
AU2002224554A1 (en) Cytochrome b5 gene and protein of candida tropicalis and methods relating thereto
EP1844135B1 (en) Escherichia strain capable of converting xmp to gmp and maintaining the inactivated state of gene(s) associated with gmp degradation and methods of using the same
CN114410561B (zh) 一种生产胸苷的基因工程菌株及其构建方法与应用
CN105861534A (zh) 一种双质粒工程菌提高l-5-甲基四氢叶酸产量的生物方法
HUP0202517A2 (hu) Az avermektinek B2:B1 arányát befolyásoló Streptomyces avermitilis gén
NZ545937A (en) Selection system containing non-antibiotic resistance selection marker
AU4302000A (en) Genome sequence and polypeptides of pyrococcus (abissy), fragment and uses thereof
CN110241062A (zh) 新大肠杆菌表达系统
AP2002002418A0 (en) Streptomyces avermitilis gene directing the ratio of B2:B1 avermectins.
RS70004A (en) Streptomyces avermitilis gene directing the ratio of b2:b1 avermectin
Couto et al. Metabolic engineering of Escherichia coli for biotechnological chondroitin production
Wang et al. CRISPR‐Cas9 mediated genome editing of Kluyveromyces marxianus for iterative, multiplexed gene disruption and pathway integration

Legal Events

Date Code Title Description
RECP Rectifications of patent specification