PL3761982T3 - Zastosowanie nalfurafiny w leczeniu chorób demielinizacyjnych - Google Patents
Zastosowanie nalfurafiny w leczeniu chorób demielinizacyjnychInfo
- Publication number
- PL3761982T3 PL3761982T3 PL19765122.7T PL19765122T PL3761982T3 PL 3761982 T3 PL3761982 T3 PL 3761982T3 PL 19765122 T PL19765122 T PL 19765122T PL 3761982 T3 PL3761982 T3 PL 3761982T3
- Authority
- PL
- Poland
- Prior art keywords
- nalfurafine
- treatment
- demyelinating diseases
- demyelinating
- diseases
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurosurgery (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2018900754A AU2018900754A0 (en) | 2018-03-08 | Treatment of demyelinating diseases | |
| PCT/IB2019/051870 WO2019171333A1 (en) | 2018-03-08 | 2019-03-07 | Treatment of demyelinating diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3761982T3 true PL3761982T3 (pl) | 2025-03-17 |
Family
ID=67846938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL19765122.7T PL3761982T3 (pl) | 2018-03-08 | 2019-03-07 | Zastosowanie nalfurafiny w leczeniu chorób demielinizacyjnych |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US20210015813A1 (pl) |
| EP (1) | EP3761982B1 (pl) |
| AU (1) | AU2019229892B2 (pl) |
| CA (1) | CA3091752A1 (pl) |
| DK (1) | DK3761982T3 (pl) |
| ES (1) | ES3006014T3 (pl) |
| FI (1) | FI3761982T3 (pl) |
| HU (1) | HUE069820T2 (pl) |
| PL (1) | PL3761982T3 (pl) |
| PT (1) | PT3761982T (pl) |
| WO (1) | WO2019171333A1 (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3761982B1 (en) | 2018-03-08 | 2024-10-09 | Victoria Link Ltd | Use of nalfurafine for the treatment of demyelinating diseases |
| WO2021186035A1 (en) | 2020-03-20 | 2021-09-23 | Medizinische Universität Wien | Cyclotides in combination with kappa opioid receptor ligands for ms therapy |
| WO2024229174A1 (en) * | 2023-05-02 | 2024-11-07 | Cognito Therapeutics, Inc. | Gamma stimulation and neuromodulator combination therapy |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4994466A (en) | 1990-06-14 | 1991-02-19 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for multiple sclerosis |
| CA2105072C (en) | 1992-01-23 | 1998-07-28 | Hiroshi Nagase | Morphinan derivative and its pharmaceutical applications |
| JP3123080B2 (ja) | 1995-09-26 | 2001-01-09 | 東レ株式会社 | 「インドール誘導体およびその医薬用途」 |
| EP1327444B1 (en) | 1996-11-25 | 2005-03-23 | Toray Industries, Inc. | Antipruritic agent |
| US6440987B1 (en) | 1996-11-25 | 2002-08-27 | Toray Industries, Inc. | Antipruritic |
| TWI285644B (en) | 1997-07-11 | 2007-08-21 | Toray Industries | A stable pharmaceutical composition containing a derivative of 4,5-epoxymorphinan and a water-soluble antioxidant, an oil-soluble antioxidant, a synergist, a sugar and a surfactant |
| JP2000053572A (ja) | 1998-08-11 | 2000-02-22 | Toray Ind Inc | ORL1(opioid orphan)受容体拮抗薬 |
| WO2001014383A1 (en) | 1999-08-24 | 2001-03-01 | Toray Industries, Inc. | Remedies for neuropathic pain and model animals of neuropathic pain |
| JP2001163784A (ja) | 1999-12-06 | 2001-06-19 | Toray Ind Inc | 角膜または結膜用止痒剤 |
| JP4370683B2 (ja) | 2000-05-08 | 2009-11-25 | 東レ株式会社 | そう痒疾患の検査方法 |
| KR20030053530A (ko) | 2000-11-22 | 2003-06-28 | 도레이 가부시끼가이샤 | 인돌 유도체 및 그 의약용도 |
| CA2442423C (en) | 2001-03-30 | 2009-11-03 | Toray Industries, Inc. | Therapeutic drug for psychoneurotic disorders |
| JP2002332284A (ja) | 2001-05-08 | 2002-11-22 | Toray Ind Inc | 二価性モルヒナン誘導体およびその医薬用途 |
| JP4957489B2 (ja) | 2002-10-09 | 2012-06-20 | 東レ株式会社 | 含窒素環状置換基を有するモルヒナン誘導体またはその薬理学的に許容される酸付加塩を含有する医薬 |
| US7320984B2 (en) | 2002-10-09 | 2008-01-22 | Toray Industries, Inc. | Remedies or preventives for urinary frequency or urinary incontinence and morphinan derivatives having nitrogen-containing heterocyclic group |
| ATE414516T1 (de) | 2004-03-30 | 2008-12-15 | Toray Industries | Morphinanderivate als mittel gegen juckreiz |
| US20060069086A1 (en) * | 2004-09-23 | 2006-03-30 | Alexander Michalow | Methods for regulating neurotransmitter systems by inducing counteradaptations |
| AR053098A1 (es) | 2004-11-04 | 2007-04-25 | Toray Industries | Analgesico derivado de morfinano |
| CA2604071C (en) | 2005-03-10 | 2013-10-08 | Toray Industries, Inc. | Antipruritic agent for pruritus caused by multiple sclerosis |
| BRPI0608671B1 (pt) | 2005-04-06 | 2022-07-19 | Toray Industries, Inc | Processos para produzir um cristal de forma a de cloridrato de 17-ciclopropilmetil-3,14 b-diidróxi-4,5a-epóxi-6b-[n-metil-trans-3-(3-furil)-acril amido]-morfinano |
| KR20080065664A (ko) | 2005-11-09 | 2008-07-14 | 도레이 가부시끼가이샤 | 기능성 장장해의 치료 또는 예방제 |
| US8106065B2 (en) | 2005-12-21 | 2012-01-31 | Toray Industries, Inc. | Antitussive agent |
| WO2008024490A2 (en) | 2006-08-24 | 2008-02-28 | Theraquest Biosciences, Inc. | Oral pharmaceutical formulations of abuse deterrent cannabinoids and method of use |
| CA2685126C (en) | 2007-04-24 | 2015-04-14 | Toray Industries, Inc. | Therapeutic or prophylactic agent for dyskinesia |
| KR101491656B1 (ko) | 2007-04-26 | 2015-02-09 | 도레이 카부시키가이샤 | 4,5-에폭시모르피난 유도체를 함유하는 안정한 고형 제제 |
| KR101173509B1 (ko) | 2007-10-05 | 2012-08-14 | 도레이 카부시키가이샤 | 모르피난 유도체 또는 그 약리학적으로 허용되는 산부가염을 유효 성분으로 하는 피부 성상 개선 치료약 |
| JP5252391B2 (ja) | 2008-02-21 | 2013-07-31 | 学校法人北里研究所 | オキサビシクロ[2.2.2]オクタンを有するモルヒナン誘導体およびその医薬用途 |
| DK2356989T3 (en) | 2008-10-24 | 2018-05-07 | Toray Industries | Stable tablet containing 4,5-epoxymorphinane derivative |
| TWI455733B (zh) | 2009-03-30 | 2014-10-11 | Toray Industries | 口腔內崩壞性被覆錠劑 |
| JP2011074018A (ja) | 2009-09-30 | 2011-04-14 | Toray Ind Inc | 線維筋痛症の治療剤又は予防剤 |
| MY173491A (en) | 2010-01-29 | 2020-01-29 | Toray Industries | Therapeutic or prophylactic agent for biliary tract diseases |
| WO2012105475A1 (ja) | 2011-01-31 | 2012-08-09 | 東レ株式会社 | 悪液質の治療又は予防剤 |
| DK2675893T3 (en) | 2011-02-18 | 2019-04-15 | Scripps Research Inst | Directed differentiation of oligodendrocyte precursor cells into a myelinating cell fate |
| US9248128B2 (en) | 2012-01-27 | 2016-02-02 | New York University | Method for enhancing remyelination using GLI1 inhibitors |
| US20150150935A1 (en) | 2012-06-05 | 2015-06-04 | Cara Therapeutics, Inc. | Peripheral kappa receptor agonists for reducing pain and inflammation |
| CN102993125A (zh) | 2012-09-25 | 2013-03-27 | 中国人民解放军第四军医大学 | 一种新的用于缺血心脏保护作用的κ-阿片受体激动剂 |
| CN104919095B (zh) | 2012-12-19 | 2017-06-30 | 加利福尼亚大学董事会 | 用于测定髓鞘形成的微柱阵列 |
| JP6359014B2 (ja) | 2013-08-21 | 2018-07-18 | 久光製薬株式会社 | 貼付剤 |
| JP6306594B2 (ja) | 2013-08-21 | 2018-04-04 | 久光製薬株式会社 | 貼付剤 |
| JP6247118B2 (ja) | 2014-03-05 | 2017-12-13 | 東海カプセル株式会社 | カプセル充填組成物 |
| JP2016155794A (ja) | 2014-06-09 | 2016-09-01 | 富士カプセル株式会社 | ナルフラフィン塩酸塩及びフィチン酸又はその塩を含有するカプセル製剤 |
| CN105462930B (zh) | 2014-06-24 | 2020-10-20 | 中国人民解放军军事医学科学院毒物药物研究所 | 一种筛选κ阿片受体激动剂的细胞模型及筛选方法 |
| TW201707703A (zh) * | 2015-06-04 | 2017-03-01 | Tokai Capsule Co Ltd | 軟膠囊劑 |
| US10525015B2 (en) | 2015-06-24 | 2020-01-07 | University Of Tsukuba | Nalfurafine-containing percutaneous absorption patch |
| WO2017049252A1 (en) | 2015-09-17 | 2017-03-23 | Switch Bio, Inc. | Compositions and methods for treating neurological disorders |
| JPWO2017094337A1 (ja) | 2015-12-04 | 2018-09-20 | ニチバン株式会社 | 貼付剤 |
| CN108883025A (zh) | 2016-03-31 | 2018-11-23 | 日绊株式会社 | 贴剂产品 |
| WO2017220431A1 (en) | 2016-06-20 | 2017-12-28 | Almirall, S.A. | Fused pyrazole derivatives as jak inhibitors |
| JP2018048093A (ja) | 2016-09-23 | 2018-03-29 | 東レ株式会社 | モルヒナン誘導体及びその医薬用途 |
| WO2018181920A1 (ja) | 2017-03-31 | 2018-10-04 | 東レ株式会社 | ナルフラフィンを含有する錠剤化された医薬組成物 |
| WO2019171332A1 (en) | 2018-03-08 | 2019-09-12 | Victoria Link Ltd | Treatment of demyelinating diseases |
| EP3761982B1 (en) | 2018-03-08 | 2024-10-09 | Victoria Link Ltd | Use of nalfurafine for the treatment of demyelinating diseases |
-
2019
- 2019-03-07 EP EP19765122.7A patent/EP3761982B1/en active Active
- 2019-03-07 FI FIEP19765122.7T patent/FI3761982T3/fi active
- 2019-03-07 HU HUE19765122A patent/HUE069820T2/hu unknown
- 2019-03-07 PT PT197651227T patent/PT3761982T/pt unknown
- 2019-03-07 CA CA3091752A patent/CA3091752A1/en active Pending
- 2019-03-07 WO PCT/IB2019/051870 patent/WO2019171333A1/en not_active Ceased
- 2019-03-07 AU AU2019229892A patent/AU2019229892B2/en active Active
- 2019-03-07 US US16/978,542 patent/US20210015813A1/en not_active Abandoned
- 2019-03-07 PL PL19765122.7T patent/PL3761982T3/pl unknown
- 2019-03-07 ES ES19765122T patent/ES3006014T3/es active Active
- 2019-03-07 DK DK19765122.7T patent/DK3761982T3/da active
-
2020
- 2020-07-23 US US16/936,975 patent/US11324742B2/en active Active
-
2022
- 2022-09-30 US US17/957,350 patent/US12318380B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019171333A1 (en) | 2019-09-12 |
| CA3091752A1 (en) | 2019-09-12 |
| US20210015813A1 (en) | 2021-01-21 |
| US11324742B2 (en) | 2022-05-10 |
| AU2019229892B2 (en) | 2025-01-30 |
| RU2020128028A (ru) | 2022-04-08 |
| EP3761982B1 (en) | 2024-10-09 |
| US12318380B2 (en) | 2025-06-03 |
| DK3761982T3 (da) | 2025-01-02 |
| EP3761982A1 (en) | 2021-01-13 |
| PT3761982T (pt) | 2024-12-30 |
| US20210069179A1 (en) | 2021-03-11 |
| EP3761982A4 (en) | 2021-12-15 |
| US20230096920A1 (en) | 2023-03-30 |
| ES3006014T3 (en) | 2025-03-17 |
| HUE069820T2 (hu) | 2025-04-28 |
| AU2019229892A1 (en) | 2020-09-03 |
| FI3761982T3 (fi) | 2025-01-03 |
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