PL374919A1 - Nowy związek indolinowy i jego zastosowanie w medycynie - Google Patents

Nowy związek indolinowy i jego zastosowanie w medycynie

Info

Publication number
PL374919A1
PL374919A1 PL03374919A PL37491903A PL374919A1 PL 374919 A1 PL374919 A1 PL 374919A1 PL 03374919 A PL03374919 A PL 03374919A PL 37491903 A PL37491903 A PL 37491903A PL 374919 A1 PL374919 A1 PL 374919A1
Authority
PL
Poland
Prior art keywords
indoline compound
medicinal use
compound
novel indoline
pharmaceutically acceptable
Prior art date
Application number
PL03374919A
Other languages
English (en)
Inventor
Shouji Kamiya
Miho Ikai
Kenji Takahashi
Tadatsugu Tarumi
Masayasu Kasai
Akihisa Yoshimi
Hiroaki Shirahase
Original Assignee
Kyoto Pharmaceutical Industries, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyoto Pharmaceutical Industries, Ltd. filed Critical Kyoto Pharmaceutical Industries, Ltd.
Publication of PL374919A1 publication Critical patent/PL374919A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
PL03374919A 2002-07-17 2003-07-16 Nowy związek indolinowy i jego zastosowanie w medycynie PL374919A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2002208878 2002-07-17

Publications (1)

Publication Number Publication Date
PL374919A1 true PL374919A1 (pl) 2005-11-14

Family

ID=30112861

Family Applications (1)

Application Number Title Priority Date Filing Date
PL03374919A PL374919A1 (pl) 2002-07-17 2003-07-16 Nowy związek indolinowy i jego zastosowanie w medycynie

Country Status (22)

Country Link
US (1) US7429612B2 (pl)
EP (1) EP1541553B1 (pl)
JP (1) JP4485357B2 (pl)
CN (1) CN100349868C (pl)
AT (1) ATE469884T1 (pl)
AU (1) AU2003252638B8 (pl)
BR (1) BR0312734A (pl)
CA (1) CA2492669A1 (pl)
CO (1) CO5690574A2 (pl)
DE (1) DE60332851D1 (pl)
DK (1) DK1541553T3 (pl)
HK (1) HK1083839A1 (pl)
IL (1) IL166313A0 (pl)
MX (1) MXPA05000749A (pl)
NO (1) NO20050834L (pl)
NZ (1) NZ538226A (pl)
PL (1) PL374919A1 (pl)
RS (1) RS20050127A (pl)
RU (1) RU2318808C2 (pl)
TW (1) TWI285196B (pl)
WO (1) WO2004007450A1 (pl)
ZA (1) ZA200501297B (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011076931A1 (de) 2011-06-03 2012-12-06 Basf Se Wässrige Lösung, enthaltend Acrylsäure und deren konjugierte Base
JP2018052818A (ja) * 2015-01-28 2018-04-05 武田薬品工業株式会社 スルホンアミド化合物

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4013404A (en) * 1970-12-06 1977-03-22 American Cyanamid Company Method of dyeing hair with indolines, indoles and indazoles
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
US4803218A (en) 1982-09-29 1989-02-07 Mcneilab, Inc. 3-aminoalkyl-1H-indole-5-urea and amide derivatives
US4956372A (en) 1987-10-02 1990-09-11 Kyorin Pharmaceutical Co., Ltd. Cyclic anthranilic acid derivatives and process for their preparation
CN1021819C (zh) 1988-01-20 1993-08-18 山之内制药株式会社 作为药物有用的双脲衍生物的制备方法
JPH02117651A (ja) 1988-01-20 1990-05-02 Yamanouchi Pharmaceut Co Ltd ジウレア誘導体及びその製造法
US5227492A (en) 1988-01-20 1993-07-13 Yamanouchi Pharmaceutical Co., Ltd. Diurea derivatives useful as medicaments and processes for the preparation thereof
US5166429A (en) 1988-01-20 1992-11-24 Yamanouchi Pharmaceutical Co., Ltd. Diurea derivatives useful as medicaments and processes for the preparation thereof
JPH0753714B2 (ja) 1988-07-12 1995-06-07 武田薬品工業株式会社 Ａｃａｔ阻害剤、キノリン誘導体及びその製造法
IE892088L (en) 1988-07-12 1990-01-12 William Henry Deryk Morris Quinoline derivatives, their production and use
US5153226A (en) 1989-08-31 1992-10-06 Warner-Lambert Company Acat inhibitors for treating hypocholesterolemia
US5258405A (en) 1990-03-12 1993-11-02 Yamanouchi Pharmaceutical Co., Ltd. Urea derivatives and salts thereof in method for inhibiting the ACAT enzyme
ES2068497T3 (es) 1990-03-12 1995-04-16 Yamanouchi Pharma Co Ltd Derivados de urea, su produccion, y composiciones farmaceuticas que los contienen.
JPH0466568A (ja) 1990-06-29 1992-03-02 Takeda Chem Ind Ltd 中枢性抗酸化剤化合物
US5143919A (en) 1990-08-17 1992-09-01 Takeda Chemical Industries, Ltd. Thienopyridine derivatives and their pharmaceutical use
JP3086295B2 (ja) 1990-08-17 2000-09-11 武田薬品工業株式会社 チエノピリジン誘導体、その製造法およびａｃａｔ阻害剤
US5256782A (en) 1990-08-17 1993-10-26 Takeda Chemical Industries, Ltd. Thienopyridine derivatives which are intermediates
FR2673625B1 (fr) 1991-03-08 1993-05-07 Adir Nouveaux derives d'acylaminophenol, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2674522B1 (fr) 1991-03-26 1993-07-16 Lipha Nouveaux derives de l'indole, procedes de preparation et medicaments les contenant.
IL101785A0 (en) 1991-05-10 1992-12-30 Fujisawa Pharmaceutical Co Urea derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
CA2121391A1 (en) 1993-04-28 1994-10-29 Atsuyuki Kojima Indoloylguanidine derivatives
US6169107B1 (en) 1993-04-28 2001-01-02 Sumitomo Pharmaceutical Co., Ltd. Indoloylguanidine derivatives
JP3720395B2 (ja) * 1994-09-20 2005-11-24 京都薬品工業株式会社 新規ヘテロ環誘導体、その製造方法およびその医薬用途
CA2160600A1 (en) 1994-10-18 1996-04-19 Masahumi Kitano Indoloylguanidine derivatives
JPH08208602A (ja) 1994-10-18 1996-08-13 Sumitomo Pharmaceut Co Ltd インドロイルグアニジン誘導体
US5767129A (en) 1995-08-24 1998-06-16 Warner-Lambert Company Substituted quinolines and isoquinolines as calcium channel blockers, their preparation and the use thereof
HUP9900617A3 (en) * 1995-10-05 2001-12-28 Kyoto Pharma Ind Novel indole-, indoline- or tetrahydrokinoline derivatives as acat and lipid peroxidation inhibitors, use thereof, pharmaceutical compositions containing these compounds
EP0793140B1 (en) 1996-03-04 2000-08-09 Fuji Photo Film Co., Ltd. Processing composition for silver halide photographic light-sensitive material, developer and processing method using the same
JP2002047269A (ja) * 2000-08-01 2002-02-12 Kyoto Pharmaceutical Industries Ltd ヘテロ環化合物の製造方法およびその中間体
JP2002302481A (ja) * 2001-02-02 2002-10-18 Sankyo Co Ltd インドリン誘導体と製造法
WO2004096767A1 (en) 2003-04-25 2004-11-11 H. Lundbeck A/S Sustituted indoline and indole derivatives

Also Published As

Publication number Publication date
EP1541553B1 (en) 2010-06-02
EP1541553A1 (en) 2005-06-15
WO2004007450A1 (ja) 2004-01-22
US20060128787A1 (en) 2006-06-15
MXPA05000749A (es) 2005-04-28
CA2492669A1 (en) 2004-01-22
TWI285196B (en) 2007-08-11
EP1541553A4 (en) 2007-04-11
AU2003252638A1 (en) 2004-02-02
CN100349868C (zh) 2007-11-21
CN1681781A (zh) 2005-10-12
TW200407304A (en) 2004-05-16
NO20050834L (no) 2005-04-15
IL166313A0 (en) 2006-01-15
DE60332851D1 (de) 2010-07-15
US7429612B2 (en) 2008-09-30
RU2318808C2 (ru) 2008-03-10
JP4485357B2 (ja) 2010-06-23
HK1083839A1 (en) 2006-07-14
RU2005104238A (ru) 2005-08-27
JPWO2004007450A1 (ja) 2005-11-10
ATE469884T1 (de) 2010-06-15
RS20050127A (en) 2007-06-04
AU2003252638B2 (en) 2009-02-05
NZ538226A (en) 2006-08-31
CO5690574A2 (es) 2006-10-31
AU2003252638B8 (en) 2009-03-05
DK1541553T3 (da) 2010-09-20
ZA200501297B (en) 2006-10-25
BR0312734A (pt) 2005-04-26

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Legal Events

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REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)