PL362835A1 - Związki laktamowe i ich zastosowanie medyczne - Google Patents

Związki laktamowe i ich zastosowanie medyczne

Info

Publication number
PL362835A1
PL362835A1 PL01362835A PL36283501A PL362835A1 PL 362835 A1 PL362835 A1 PL 362835A1 PL 01362835 A PL01362835 A PL 01362835A PL 36283501 A PL36283501 A PL 36283501A PL 362835 A1 PL362835 A1 PL 362835A1
Authority
PL
Poland
Prior art keywords
diabetic
lactam compounds
medicinal use
agent
adiposis
Prior art date
Application number
PL01362835A
Other languages
English (en)
Inventor
Yukio Iino
Takao Ikenoue
Nobuo Kondo
Hiroyuki Matsueda
Toshihiro Hatanaka
Ryusuke Hirama
Yoko Masuzawa
Fumio Ohta
Akiyo Yamazaki
Original Assignee
Ajinomoto Co,Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co,Inc. filed Critical Ajinomoto Co,Inc.
Publication of PL362835A1 publication Critical patent/PL362835A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrrole Compounds (AREA)
PL01362835A 2000-12-01 2001-11-29 Związki laktamowe i ich zastosowanie medyczne PL362835A1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000367175 2000-12-01
PCT/JP2001/010435 WO2002044180A1 (fr) 2000-12-01 2001-11-29 Composes de lactame et leur utilisation medicale

Publications (1)

Publication Number Publication Date
PL362835A1 true PL362835A1 (pl) 2004-11-02

Family

ID=18837660

Family Applications (1)

Application Number Title Priority Date Filing Date
PL01362835A PL362835A1 (pl) 2000-12-01 2001-11-29 Związki laktamowe i ich zastosowanie medyczne

Country Status (26)

Country Link
US (3) US7153850B2 (pl)
EP (1) EP1346993B1 (pl)
JP (2) JP3826400B2 (pl)
KR (1) KR100826818B1 (pl)
CN (2) CN100577651C (pl)
AT (1) ATE446297T1 (pl)
AU (3) AU2002218502B2 (pl)
BG (1) BG107857A (pl)
BR (1) BR0115852A (pl)
CA (1) CA2430124C (pl)
CZ (1) CZ20031520A3 (pl)
DE (1) DE60140270D1 (pl)
ES (1) ES2331299T3 (pl)
HU (1) HUP0400806A3 (pl)
IL (1) IL156158A0 (pl)
MX (1) MXPA03004876A (pl)
NO (1) NO325401B1 (pl)
NZ (1) NZ526164A (pl)
PL (1) PL362835A1 (pl)
RU (1) RU2287530C2 (pl)
SK (1) SK6582003A3 (pl)
TW (1) TWI241302B (pl)
UA (1) UA76969C2 (pl)
WO (1) WO2002044180A1 (pl)
YU (1) YU42603A (pl)
ZA (1) ZA200304100B (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2430124C (en) * 2000-12-01 2011-01-11 Ajinomoto Co., Inc. Lactam compounds and pharmaceutical use thereof
AU2004210268B8 (en) * 2003-02-07 2009-06-04 Ajinomoto Co., Inc. Therapeutic agents for diabetes
JP4711228B2 (ja) * 2003-10-31 2011-06-29 味の素株式会社 複素環を有する新規縮合多環式化合物及びその医薬用途
JPWO2005068467A1 (ja) 2004-01-14 2007-12-27 味の素株式会社 新規縮環化合物
BRPI0610034A2 (pt) * 2005-04-28 2011-10-18 Ajinomoto Kk composto, agente de icremento do transporte de açúcar, agente hipoglicêmico, agente para prevenção e/ou tratamento de uma doença, medicamento, composição farmacêutica , uso do composto, e, método de preparação para o composto
JP5672699B2 (ja) 2007-04-11 2015-02-18 味の素株式会社 血糖降下作用化合物のスクリーニング法
WO2008139575A1 (ja) * 2007-04-27 2008-11-20 Ajinomoto Co., Inc. 経口投与用製剤
WO2008136394A1 (ja) * 2007-04-27 2008-11-13 Ajinomoto Co., Inc. ラクタム化合物の製造方法及びその製造中間体
WO2008139574A1 (ja) * 2007-04-27 2008-11-20 Ajinomoto Co., Inc. ラクタム化合物の結晶形およびその製造方法
CN101619041B (zh) * 2008-07-02 2012-07-04 重庆华邦制药股份有限公司 一种二酮基含氮环化合物的合成方法及其中间体
JP2012180282A (ja) * 2009-07-02 2012-09-20 Ajinomoto Co Inc ラクタム化合物の製造方法およびその製造中間体
JP2012180283A (ja) * 2009-07-02 2012-09-20 Ajinomoto Co Inc ラクタム化合物の製造方法およびその製造中間体
RU2017126027A (ru) * 2014-12-22 2019-01-24 ЕА Фарма Ко., Лтд. Лекарственное средство для лечения расстройств эпителия роговицы
US11548893B2 (en) 2017-07-15 2023-01-10 Arisan Therapeutics Inc. Enantiomerically pure adamantane carboxamides for the treatment of filovirus infection
MX2021008937A (es) * 2019-01-23 2021-11-12 Glycolysis Biomed Co Ltd Compuestos de beta-lactama o sales de los mismos para su uso en la prevencion o tratamiento de accion prolongada del trastorno del metabolismo de la glucosa.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US189597A (en) * 1877-04-17 Improvement in portable wash-stands
US48847A (en) * 1865-07-18 Improvement in vessels for reception and transportation of night-soil
DE69826677T2 (de) 1997-07-30 2005-02-10 Wyeth Trizyclische Vasopressin-Agonisten
JP4204657B2 (ja) * 1997-12-05 2009-01-07 有限会社ケムフィズ 糖尿病の予防・治療剤
CA2430124C (en) * 2000-12-01 2011-01-11 Ajinomoto Co., Inc. Lactam compounds and pharmaceutical use thereof
AU2004210268B8 (en) * 2003-02-07 2009-06-04 Ajinomoto Co., Inc. Therapeutic agents for diabetes

Also Published As

Publication number Publication date
CN1269818C (zh) 2006-08-16
ES2331299T3 (es) 2009-12-29
NZ526164A (en) 2004-09-24
US20060189597A1 (en) 2006-08-24
HUP0400806A2 (hu) 2004-07-28
AU2002218502B2 (en) 2006-09-21
NO325401B1 (no) 2008-04-21
AU2006241377B2 (en) 2009-01-08
CN1911915A (zh) 2007-02-14
RU2287530C2 (ru) 2006-11-20
CA2430124C (en) 2011-01-11
IL156158A0 (en) 2003-12-23
AU1850202A (en) 2002-06-11
JPWO2002044180A1 (ja) 2004-04-02
BR0115852A (pt) 2003-12-23
CN100577651C (zh) 2010-01-06
US20080096862A1 (en) 2008-04-24
EP1346993A1 (en) 2003-09-24
US7153850B2 (en) 2006-12-26
EP1346993B1 (en) 2009-10-21
KR20030051893A (ko) 2003-06-25
JP2006213732A (ja) 2006-08-17
YU42603A (sh) 2006-03-03
JP4505753B2 (ja) 2010-07-21
KR100826818B1 (ko) 2008-05-02
CA2430124A1 (en) 2002-06-06
AU2006241377A1 (en) 2006-12-14
US7632830B2 (en) 2009-12-15
ATE446297T1 (de) 2009-11-15
MXPA03004876A (es) 2004-01-27
TWI241302B (en) 2005-10-11
UA76969C2 (en) 2006-10-16
US20040048847A1 (en) 2004-03-11
SK6582003A3 (en) 2003-09-11
CN1487940A (zh) 2004-04-07
NO20032439L (no) 2003-07-18
DE60140270D1 (de) 2009-12-03
WO2002044180A1 (fr) 2002-06-06
BG107857A (bg) 2004-06-30
US7326701B2 (en) 2008-02-05
CZ20031520A3 (cs) 2003-10-15
NO20032439D0 (no) 2003-05-28
JP3826400B2 (ja) 2006-09-27
ZA200304100B (en) 2004-08-22
EP1346993A4 (en) 2005-12-21
HUP0400806A3 (en) 2007-11-28

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Legal Events

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REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)