PL3603620T3 - Kompozycja liposomowa i kompozycja farmaceutyczna - Google Patents

Kompozycja liposomowa i kompozycja farmaceutyczna

Info

Publication number
PL3603620T3
PL3603620T3 PL18776957.5T PL18776957T PL3603620T3 PL 3603620 T3 PL3603620 T3 PL 3603620T3 PL 18776957 T PL18776957 T PL 18776957T PL 3603620 T3 PL3603620 T3 PL 3603620T3
Authority
PL
Poland
Prior art keywords
composition
liposome
pharmaceutical composition
pharmaceutical
liposome composition
Prior art date
Application number
PL18776957.5T
Other languages
English (en)
Inventor
Noriyuki Kasagi
Naoki Yamada
Mikinaga Mori
Takayuki Kato
Takayuki Kobayashi
Original Assignee
Fujifilm Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm Corporation filed Critical Fujifilm Corporation
Publication of PL3603620T3 publication Critical patent/PL3603620T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/02Ammonia; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL18776957.5T 2017-03-31 2018-03-30 Kompozycja liposomowa i kompozycja farmaceutyczna PL3603620T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017069836 2017-03-31
PCT/JP2018/013783 WO2018181963A1 (ja) 2017-03-31 2018-03-30 リポソーム組成物および医薬組成物

Publications (1)

Publication Number Publication Date
PL3603620T3 true PL3603620T3 (pl) 2026-02-16

Family

ID=63676279

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18776957.5T PL3603620T3 (pl) 2017-03-31 2018-03-30 Kompozycja liposomowa i kompozycja farmaceutyczna

Country Status (20)

Country Link
US (3) US11413244B2 (pl)
EP (1) EP3603620B1 (pl)
JP (3) JP6728482B2 (pl)
KR (1) KR102328463B1 (pl)
CN (4) CN110505869A (pl)
AU (1) AU2018246024B2 (pl)
BR (1) BR112019020406B1 (pl)
CA (1) CA3058127C (pl)
DK (1) DK3603620T3 (pl)
ES (1) ES3055110T3 (pl)
FI (1) FI3603620T3 (pl)
HR (1) HRP20251519T1 (pl)
LT (1) LT3603620T (pl)
PL (1) PL3603620T3 (pl)
PT (1) PT3603620T (pl)
RS (1) RS67470B1 (pl)
RU (1) RU2734900C1 (pl)
SI (1) SI3603620T1 (pl)
SM (1) SMT202500440T1 (pl)
WO (1) WO2018181963A1 (pl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3603620T1 (sl) 2017-03-31 2026-01-30 Fujifilm Corporation Sestava liposomov in farmacevtska sestava
FI3811931T3 (fi) * 2018-06-20 2024-09-12 Fujifilm Corp Liposomikoostumukseen kapseloidun lääkkeen ja immuunitarkistuspisteinhibiittorin sisältävä yhdistelmälääkitys
WO2020071349A1 (ja) * 2018-10-01 2020-04-09 富士フイルム株式会社 薬物を内包するリポソーム組成物およびプラチナ製剤を含む組合せ医薬
EP3897665A4 (en) 2018-12-17 2022-09-28 Eisai R&D Management Co., Ltd. FORMULATION INCLUDING LIPOSOMES
US20230172856A1 (en) * 2020-05-06 2023-06-08 Nanotech Pharma Inc. Liposome formulations for treatment of cancers and drug resistance of cancers
CN113876711A (zh) * 2020-07-01 2022-01-04 江苏长泰药业有限公司 一种盐酸阿霉素脂质体的制备工艺
CN116635009A (zh) * 2020-12-14 2023-08-22 纳米科技制药公司 用于递送抗癌剂的具有改进的治疗指数的组合物和方法
JP6884496B1 (ja) * 2021-03-08 2021-06-09 ユーシービージャパン株式会社 レベチラセタムを有効成分とする注射用製剤
CN113101374B (zh) * 2021-04-08 2022-10-25 陕西科技大学 一种阿拉伯胶-明胶修饰牡丹籽油纳米脂质体及其制备方法
TW202313031A (zh) * 2021-05-24 2023-04-01 日商富士軟片股份有限公司 抗腫瘤劑
EP4349338A4 (en) * 2021-05-24 2024-09-04 FUJIFILM Corporation TREATMENT AGENT
AU2023242146A1 (en) * 2022-03-31 2024-09-05 Eisai R&D Management Co., Ltd. Liposome composition and liposome-containing pharmaceutical composition
EP4623915A4 (en) 2022-11-21 2026-04-01 Fujifilm Corp COMBINATION MEDICINE COMPRISING A LIPOSOME COMPOSITION CONTAINING TOPOTECAN OR A SALT THEREOF ENCAPSULATED THEREIN AND A DNA DAMAGE REPAIR INHIBITOR
GB202315012D0 (en) * 2023-09-29 2023-11-15 Univ Bath Composition

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL91664A (en) 1988-09-28 1993-05-13 Yissum Res Dev Co Ammonium transmembrane gradient system for efficient loading of liposomes with amphipathic drugs and their controlled release
US5543152A (en) 1994-06-20 1996-08-06 Inex Pharmaceuticals Corporation Sphingosomes for enhanced drug delivery
JP2002527466A (ja) 1998-09-16 2002-08-27 アルザ・コーポレーション リポソーム−閉込めトポイソメラーゼ阻害剤
MXPA02012817A (es) 2000-06-30 2004-07-30 Inex Pharmaceuticals Inc Drogas antineoplasicas liposomales y uso de las mismas.
US20080075762A1 (en) 2001-10-03 2008-03-27 Paul Tardi Compositions for delivery of drug combinations
US20070231379A1 (en) * 2002-08-29 2007-10-04 Slater James L Liposome-entrapped topoisomerase inhibitors
ATE450251T1 (de) * 2004-05-17 2009-12-15 Tekmira Pharmaceuticals Corp Liposomale formulierungen mit dihydrosphingomyelin und verfahren zu ihrer verwendung
JP4990786B2 (ja) * 2004-11-05 2012-08-01 イネックス ファーマシューティカルズ コーポレイション 薬物リポソーム製剤を安定化するための組成物および方法
CN103059138B (zh) 2005-05-09 2015-10-28 小野药品工业株式会社 程序性死亡-1(pd-1)的人单克隆抗体及使用抗pd-1抗体来治疗癌症的方法
WO2006127962A2 (en) * 2005-05-25 2006-11-30 Becton, Dickinson And Comapny Particulate formulations for intradermal delivery of biologically active agents
US20080206139A1 (en) * 2006-11-03 2008-08-28 The Penn State Research Foundation Delivery system for diagnostic and therapeutic agents
CN101485629B (zh) * 2008-01-16 2013-01-23 沈阳药科大学 一种给药系统及其制备方法
US20110159080A1 (en) 2008-06-03 2011-06-30 Colin Lowery Composition comprising liposome-entrapped doxorubicin and methods of administration
AR076634A1 (es) * 2008-11-21 2011-06-29 Medgenesis Therapeutix Inc Composiciones y metodo para tratar desordenes del sistema nervioso central
WO2010110923A2 (en) 2009-03-27 2010-09-30 Robert Sabin Prophylactic and therapeutic treatment of alzheimer's disease
JP5551683B2 (ja) 2009-03-30 2014-07-16 エーザイ・アール・アンド・ディー・マネジメント株式会社 リポソーム組成物
US11357728B2 (en) * 2009-10-26 2022-06-14 Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. Liposome having inner water phase containing sulfobutyl ether cyclodextrin salt
WO2011092708A2 (en) * 2010-02-01 2011-08-04 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Liposomes comprising amphipathic drugs and method for their preparation
EP2630953B1 (en) 2010-12-27 2017-08-09 Terumo Kabushiki Kaisha Liposome composition and process for production thereof
WO2013059922A1 (en) * 2011-10-25 2013-05-02 The University Of British Columbia Limit size lipid nanoparticles and related methods
CN102764234A (zh) 2012-08-03 2012-11-07 上海现代药物制剂工程研究中心有限公司 一种盐酸拓扑替康靶向脂质体制剂及其制备方法
CA2886064A1 (en) * 2012-10-19 2014-04-24 The Regents Of The University Of California Treating tumors of the central nervous system
US20160194625A1 (en) * 2013-09-03 2016-07-07 Moderna Therapeutics, Inc. Chimeric polynucleotides
CN104771361B (zh) * 2014-01-14 2018-06-01 中国科学院上海药物研究所 一种盐酸拓扑替康脂质体纳米制剂及其制备方法
US10369104B2 (en) 2014-04-01 2019-08-06 Children's Hospital Los Angeles Targeted polymerized nanoparticles for cancer treatment
JP6316182B2 (ja) * 2014-12-19 2018-04-25 富士フイルム株式会社 リポソームの製造方法及びリポソーム製造装置
PL3372232T3 (pl) 2015-11-02 2021-09-27 Fujifilm Corporation Środek terapeutyczny do leczenia nowotworu zawierający zestaw i kompozycję liposomową gemcytabiny
WO2017079303A1 (en) 2015-11-02 2017-05-11 The Cleveland Clinic Foundation Sequentially orchestrated immune checkpoint therapy for the treatment and prevention of cancer
WO2018083470A1 (en) 2016-11-02 2018-05-11 Ipsen Biopharm Ltd. Treating gastric cancer using combination therapies comprising liposomal irinotecan, oxaliplatin, 5-fluoruracil (and leucovorin)
IL303038B2 (en) 2016-12-05 2024-08-01 G1 Therapeutics Inc Preservation of immune response during chemotherapy regimens
SI3603620T1 (sl) * 2017-03-31 2026-01-30 Fujifilm Corporation Sestava liposomov in farmacevtska sestava
FI3811931T3 (fi) 2018-06-20 2024-09-12 Fujifilm Corp Liposomikoostumukseen kapseloidun lääkkeen ja immuunitarkistuspisteinhibiittorin sisältävä yhdistelmälääkitys
WO2020071349A1 (ja) 2018-10-01 2020-04-09 富士フイルム株式会社 薬物を内包するリポソーム組成物およびプラチナ製剤を含む組合せ医薬

Also Published As

Publication number Publication date
AU2018246024A1 (en) 2019-10-17
JP2020158542A (ja) 2020-10-01
WO2018181963A1 (ja) 2018-10-04
CA3058127C (en) 2022-07-05
KR20190120319A (ko) 2019-10-23
EP3603620B1 (en) 2025-10-29
BR112019020406A2 (pt) 2020-04-22
CN114224840A (zh) 2022-03-25
LT3603620T (lt) 2025-12-10
EP3603620A4 (en) 2020-03-25
JP2022043357A (ja) 2022-03-15
FI3603620T3 (fi) 2025-12-02
JP7012124B2 (ja) 2022-01-27
BR112019020406B1 (pt) 2021-10-26
PT3603620T (pt) 2025-12-02
US11446247B2 (en) 2022-09-20
RU2734900C1 (ru) 2020-10-26
SI3603620T1 (sl) 2026-01-30
US20220370352A1 (en) 2022-11-24
KR102328463B1 (ko) 2021-11-17
JPWO2018181963A1 (ja) 2020-01-16
EP3603620A1 (en) 2020-02-05
CA3058127A1 (en) 2018-10-04
US20210038518A1 (en) 2021-02-11
ES3055110T3 (en) 2026-02-10
JP7278436B2 (ja) 2023-05-19
CN116763734A (zh) 2023-09-19
DK3603620T3 (da) 2025-12-01
US20200016079A1 (en) 2020-01-16
SMT202500440T1 (it) 2026-01-12
HRP20251519T1 (hr) 2026-01-02
JP6728482B2 (ja) 2020-07-22
CN110505869A (zh) 2019-11-26
RS67470B1 (sr) 2025-12-31
US11413244B2 (en) 2022-08-16
CN116763733A (zh) 2023-09-19
AU2018246024B2 (en) 2020-08-06

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