DK3388085T3 - Farmaceutisk sammensætning og anvendelser deraf - Google Patents

Farmaceutisk sammensætning og anvendelser deraf Download PDF

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Publication number
DK3388085T3
DK3388085T3 DK16856629.7T DK16856629T DK3388085T3 DK 3388085 T3 DK3388085 T3 DK 3388085T3 DK 16856629 T DK16856629 T DK 16856629T DK 3388085 T3 DK3388085 T3 DK 3388085T3
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DK
Denmark
Prior art keywords
pharmaceutical composition
pharmaceutical
composition
Prior art date
Application number
DK16856629.7T
Other languages
English (en)
Inventor
Alan Y Lu
Huanlong Qin
Menghan Liu
Patrick Y Lu
Original Assignee
Sirnaomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sirnaomics Inc filed Critical Sirnaomics Inc
Application granted granted Critical
Publication of DK3388085T3 publication Critical patent/DK3388085T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57419—Specifically defined cancers of colon

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK16856629.7T 2015-10-21 2016-06-13 Farmaceutisk sammensætning og anvendelser deraf DK3388085T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201510685343.0A CN105363042B (zh) 2015-10-21 2015-10-21 一种药物组合物及其应用
PCT/CN2016/085605 WO2017067188A1 (zh) 2015-10-21 2016-06-13 一种药物组合物及其应用

Publications (1)

Publication Number Publication Date
DK3388085T3 true DK3388085T3 (da) 2021-03-22

Family

ID=55365991

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16856629.7T DK3388085T3 (da) 2015-10-21 2016-06-13 Farmaceutisk sammensætning og anvendelser deraf

Country Status (6)

Country Link
US (2) US20180369273A1 (da)
EP (1) EP3388085B1 (da)
CN (1) CN105363042B (da)
DK (1) DK3388085T3 (da)
ES (1) ES2870477T3 (da)
WO (1) WO2017067188A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10300153B2 (en) * 2015-11-30 2019-05-28 Asthra, Llc Immunological detection of altered cells
CN109477090B (zh) * 2016-04-14 2022-03-22 e-NA生物科技公司 微小rna-143衍生物
CN109628601A (zh) * 2019-02-23 2019-04-16 南华大学 一种与5-氟尿嘧啶耐药性相关的microRNA分子及其应用
CN109913454B (zh) * 2019-03-05 2021-08-10 上海珑欣生物医学科技有限公司 一种生物活性提高的microRNA及其应用
CN113296360B (zh) * 2021-05-21 2024-06-14 上海邃铸科技有限公司 用于光刻胶组合物的酸抑制剂、制备方法及光刻胶组合物
CN114053294A (zh) * 2021-11-05 2022-02-18 复旦大学附属中山医院 miR-150及负载miR-150模拟物的外泌体在制备治疗结直肠癌药物上的应用
CN116370493B (zh) * 2022-04-02 2025-08-26 圣诺生物医药技术(苏州)有限公司 一种用于抑制pcsk9基因表达的核酸干扰药物组合物及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1812016A4 (en) * 2004-11-17 2010-07-14 Univ Maryland HIGH-BRANCHED HK-PEPTIDES AS EFFECTIVE CARRIER FROM SIRNA
EP2796554A3 (en) * 2005-09-12 2014-12-10 The Ohio State University Research Foundation Compositions for use in treating BCL2-associated cancers
WO2009104051A2 (en) * 2007-12-31 2009-08-27 Lu Patrick Y Combinational therapeutics for treatment of prostate cancer using epoxy encapsulated magnetic particles and rnai medicine
WO2011029903A1 (en) * 2009-09-10 2011-03-17 Flemming Velin Method for the preparation of micro-rna and its therapeutic application
CN103007291B (zh) * 2011-09-26 2015-04-29 苏州圣诺生物医药技术有限公司 双靶标/多靶标小核酸治疗眼部疾病的组合物及应用
CN103361408A (zh) * 2012-04-10 2013-10-23 马延磊 分子miR-150在筛选制备检测大肠癌药物中的应用
CN102776193A (zh) * 2012-07-20 2012-11-14 苏州大学 一种微小rna用于调控b7-h3基因表达
CN103623425B (zh) * 2012-08-27 2016-12-21 苏州圣诺生物医药技术有限公司 应用双靶标拮抗寡核酸抑制新血管增生疾病的药物
US20160145628A1 (en) * 2013-06-18 2016-05-26 Ramot At Tel-Aviv University Ltd. Nanocarrier system for micrornas and uses thereof
EP3600341A4 (en) * 2017-03-19 2022-07-06 Suzhou Sirnaomics Biopharmaceuticals Co., Ltd. GEMCITA BIN DERIVATIVES FOR CANCER THERAPY

Also Published As

Publication number Publication date
US20180369273A1 (en) 2018-12-27
ES2870477T3 (es) 2021-10-27
CN105363042B (zh) 2022-05-06
EP3388085B1 (en) 2020-12-16
WO2017067188A1 (zh) 2017-04-27
CN105363042A (zh) 2016-03-02
US20240139228A1 (en) 2024-05-02
EP3388085A4 (en) 2019-09-04
EP3388085A1 (en) 2018-10-17

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