PL3574895T3 - Zmniejszanie wielkości cząstek związku przeciwmuskarynowego - Google Patents

Zmniejszanie wielkości cząstek związku przeciwmuskarynowego

Info

Publication number
PL3574895T3
PL3574895T3 PL19182996.9T PL19182996T PL3574895T3 PL 3574895 T3 PL3574895 T3 PL 3574895T3 PL 19182996 T PL19182996 T PL 19182996T PL 3574895 T3 PL3574895 T3 PL 3574895T3
Authority
PL
Poland
Prior art keywords
particle size
size reduction
antimuscarinic compound
antimuscarinic
compound
Prior art date
Application number
PL19182996.9T
Other languages
English (en)
Inventor
Irene PASQUALI
Andrea CASAZZA
Mark Saunders
Elena Losi
Original Assignee
Chiesi Farmaceutici S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farmaceutici S.P.A. filed Critical Chiesi Farmaceutici S.P.A.
Publication of PL3574895T3 publication Critical patent/PL3574895T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL19182996.9T 2013-04-26 2014-04-24 Zmniejszanie wielkości cząstek związku przeciwmuskarynowego PL3574895T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP13165483 2013-04-26

Publications (1)

Publication Number Publication Date
PL3574895T3 true PL3574895T3 (pl) 2023-06-19

Family

ID=48190260

Family Applications (2)

Application Number Title Priority Date Filing Date
PL19182996.9T PL3574895T3 (pl) 2013-04-26 2014-04-24 Zmniejszanie wielkości cząstek związku przeciwmuskarynowego
PL14724332T PL2988728T3 (pl) 2013-04-26 2014-04-24 Zmniejszanie wielkości cząstek związku przeciwmuskarynowego

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL14724332T PL2988728T3 (pl) 2013-04-26 2014-04-24 Zmniejszanie wielkości cząstek związku przeciwmuskarynowego

Country Status (28)

Country Link
US (2) US9393202B2 (pl)
EP (2) EP3574895B1 (pl)
JP (1) JP6449246B2 (pl)
KR (1) KR102198354B1 (pl)
CN (1) CN105120841B (pl)
AR (1) AR096087A1 (pl)
AU (1) AU2014259443B2 (pl)
BR (1) BR112015024626B1 (pl)
CA (1) CA2910314C (pl)
DK (2) DK3574895T3 (pl)
ES (2) ES2943109T3 (pl)
FI (1) FI3574895T3 (pl)
HK (1) HK1216302A1 (pl)
HR (2) HRP20230337T1 (pl)
HU (2) HUE062002T2 (pl)
IL (1) IL242209A (pl)
MX (1) MX365295B (pl)
MY (1) MY169127A (pl)
PH (1) PH12015502449B1 (pl)
PL (2) PL3574895T3 (pl)
PT (2) PT2988728T (pl)
RU (1) RU2667636C2 (pl)
SG (1) SG11201508760VA (pl)
SI (2) SI2988728T1 (pl)
TW (1) TWI630926B (pl)
UA (1) UA120418C2 (pl)
WO (1) WO2014173987A1 (pl)
ZA (1) ZA201507916B (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9393202B2 (en) * 2013-04-26 2016-07-19 Chiesi Farmaceutici S.P.A Particle size reduction of an antimuscarinic compound
KR20160029797A (ko) 2013-07-11 2016-03-15 키에시 파르마슈티시 엣스. 피. 에이. 흡입에 의한 투여를 위한 항콜린제, 코르티코스테로이드 및 베타-아드레날린성 약물을 포함하는 건조 분말 제제
KR20170070151A (ko) 2014-10-16 2017-06-21 테바 브랜디드 파마슈티컬 프로덕츠 알앤디, 인코포레이티드 흡입형 제제
JP6500522B2 (ja) * 2015-03-16 2019-04-17 セイコーエプソン株式会社 回路装置、物理量検出装置、電子機器及び移動体
HUE050343T2 (hu) 2015-11-16 2020-11-30 Chiesi Farm Spa Eljárás antikolinerg szert, kortikoszteroidot és béta-adrenerg szert tartalmazó száraz porkészítmény elõállítására
SI3628331T1 (sl) 2015-11-16 2021-11-30 Chiesi Farmaceutici S.P.A. Postopek za pripravo suhe praškaste formulacije, ki obsega antiholinergik, kortikosteroid in beta-adrenergik
US9925168B2 (en) * 2016-01-22 2018-03-27 Chiesi Farmaceutici S.P.A. Preparation of micronized particles of an antimuscarinic compound by hydrodynamic cavitation
JP6323846B2 (ja) * 2016-04-07 2018-05-16 塩野義製薬株式会社 オピオイドを含有する乱用防止製剤
PT109445B (pt) * 2016-06-08 2018-11-06 Hovione Farm Sa Co-cristais farmacêuticos cristalinos de brometo de glicopirrónio com lactose
ES2805434T3 (es) * 2016-07-29 2021-02-12 Inke Sa Procedimiento de estabilización de tamaño de partícula

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5399363A (en) * 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
HUT70952A (en) * 1992-06-10 1995-11-28 Eastman Kodak Co Surface modified nanoparticles based on nosteroidal inflammatory drugs, process for preparing them and pharmaceutical compns. contg. them
GB0008660D0 (en) 2000-04-07 2000-05-31 Arakis Ltd The treatment of respiratory diseases
CN1713893A (zh) * 2002-11-18 2005-12-28 纳幕尔杜邦公司 采用非球形研磨介质的介质研磨
GB0321607D0 (en) 2003-09-15 2003-10-15 Vectura Ltd Manufacture of pharmaceutical compositions
GB0409703D0 (en) * 2004-04-30 2004-06-02 Vectura Ltd Pharmaceutical compositions
GB0516549D0 (en) 2005-08-12 2005-09-21 Sulaiman Brian Milling system
GB0613161D0 (en) * 2006-06-30 2006-08-09 Novartis Ag Organic Compounds
KR20100095587A (ko) * 2007-12-13 2010-08-31 노파르티스 아게 유기 화합물
KR20100099281A (ko) * 2007-12-13 2010-09-10 노파르티스 아게 유기 화합물
DE102008000482A1 (de) 2008-03-03 2009-09-10 Zf Friedrichshafen Ag Ölgekühltes Reibschaltelement
ES2611031T3 (es) * 2008-07-18 2017-05-04 Prosonix Limited Proceso de mejora de la cristalinidad
PL3106149T3 (pl) * 2009-05-29 2020-06-01 Pearl Therapeutics, Inc. Kompozycje do płucnego dostarczania długo-działających antagonistów muskarynowych i długo-działających agonistów receptora beta-2 adrenergicznego oraz powiązane sposoby i układy
US20150093440A1 (en) * 2010-10-15 2015-04-02 Glaxo Group Limited Aggregate nanoparticulate medicament formulations, manufacture and use thereof
US9393202B2 (en) * 2013-04-26 2016-07-19 Chiesi Farmaceutici S.P.A Particle size reduction of an antimuscarinic compound

Also Published As

Publication number Publication date
FI3574895T3 (fi) 2023-05-25
HK1216302A1 (zh) 2016-11-04
SI3574895T1 (sl) 2023-05-31
RU2015145521A (ru) 2017-05-16
MX2015014904A (es) 2016-03-07
IL242209A (en) 2017-12-31
DK3574895T3 (da) 2023-05-01
BR112015024626A2 (pt) 2017-07-18
JP2016521274A (ja) 2016-07-21
ZA201507916B (en) 2017-05-31
MX365295B (es) 2019-05-29
TWI630926B (zh) 2018-08-01
RU2667636C2 (ru) 2018-09-21
WO2014173987A1 (en) 2014-10-30
ES2943109T3 (es) 2023-06-09
PL2988728T3 (pl) 2020-02-28
EP2988728B1 (en) 2019-08-21
SG11201508760VA (en) 2015-11-27
US9889094B2 (en) 2018-02-13
AU2014259443B2 (en) 2019-01-03
PH12015502449A1 (en) 2016-02-22
CA2910314A1 (en) 2014-10-30
TW201521790A (zh) 2015-06-16
CA2910314C (en) 2022-03-01
EP2988728A1 (en) 2016-03-02
KR20160002733A (ko) 2016-01-08
US20140322142A1 (en) 2014-10-30
US9393202B2 (en) 2016-07-19
KR102198354B1 (ko) 2021-01-06
EP3574895A1 (en) 2019-12-04
HUE062002T2 (hu) 2023-09-28
AU2014259443A1 (en) 2015-11-12
AR096087A1 (es) 2015-12-02
DK2988728T3 (da) 2019-11-04
ES2754255T3 (es) 2020-04-16
PT3574895T (pt) 2023-04-28
CN105120841A (zh) 2015-12-02
US20160279066A1 (en) 2016-09-29
UA120418C2 (uk) 2019-12-10
EP3574895B1 (en) 2023-03-22
HRP20191882T1 (hr) 2019-12-27
PH12015502449B1 (en) 2016-02-22
JP6449246B2 (ja) 2019-01-09
CN105120841B (zh) 2019-04-30
HRP20230337T1 (hr) 2023-06-09
HUE046213T2 (hu) 2020-02-28
BR112015024626B1 (pt) 2022-11-01
PT2988728T (pt) 2019-11-18
MY169127A (en) 2019-02-18
SI2988728T1 (sl) 2019-11-29

Similar Documents

Publication Publication Date Title
IL276456B (en) Tetrahydroquinoline preparations as bromodomain bet inhibitors
IL249517A0 (en) A compound that inhibits trk
HK1216302A1 (zh) 抗毒蕈鹼化合物的粒度減小
GB201302368D0 (en) Compound
HK1219100A1 (zh) 吡啶基吡唑並喹啉化合物
EP2947066A4 (en) PHENOXYALKYLAMINVERBINDUNG
GB201307295D0 (en) Brake shield
IL241070A0 (en) Powder particles with additional coating
EP3010982A4 (en) ENCAPSULATION OF SOLID PARTICLES
GB201307331D0 (en) Compound
HK1208689A1 (en) Particle size reduction
GB201408643D0 (en) Compound
GB2513424B (en) Apparatus for reducing particle size
PL2948131T3 (pl) Formowanie struktur cząstkowych
GB201322438D0 (en) Compound
GB201315772D0 (en) Compound
GB201305634D0 (en) Compound
GB201304250D0 (en) Compound
GB201301585D0 (en) Compound