|
EE05627B1
(et)
*
|
1998-12-23 |
2013-02-15 |
Pfizer Inc. |
CTLA-4 vastased inimese monoklonaalsed antikehad
|
|
US7109003B2
(en)
|
1998-12-23 |
2006-09-19 |
Abgenix, Inc. |
Methods for expressing and recovering human monoclonal antibodies to CTLA-4
|
|
US7605238B2
(en)
|
1999-08-24 |
2009-10-20 |
Medarex, Inc. |
Human CTLA-4 antibodies and their uses
|
|
US7030219B2
(en)
|
2000-04-28 |
2006-04-18 |
Johns Hopkins University |
B7-DC, Dendritic cell co-stimulatory molecules
|
|
US7357928B2
(en)
*
|
2002-04-08 |
2008-04-15 |
University Of Louisville Research Foundation, Inc. |
Method for the diagnosis and prognosis of malignant diseases
|
|
CA2481207C
(en)
*
|
2002-04-12 |
2015-06-30 |
Medarex, Inc. |
Methods of treatment using ctla-4 antibodies
|
|
RS52889B
(sr)
|
2002-09-06 |
2014-02-28 |
Amgen Inc |
Terapijsko humano anti-il-1r1 monoklonsko antitelo
|
|
US20040197312A1
(en)
*
|
2003-04-02 |
2004-10-07 |
Marina Moskalenko |
Cytokine-expressing cellular vaccine combinations
|
|
US7465446B2
(en)
|
2003-05-30 |
2008-12-16 |
Medarex, Inc. |
Surrogate therapeutic endpoint for anti-CTLA4-based immunotherapy of disease
|
|
KR101531400B1
(ko)
|
2003-06-27 |
2015-06-26 |
암젠 프레몬트 인코포레이티드 |
상피 성장 인자 수용체의 결실 돌연변이체 지향 항체 및 그용도
|
|
NZ544911A
(en)
|
2003-07-22 |
2008-12-24 |
Schering Ag |
RG1 antibodies and uses thereof
|
|
CA2535859A1
(en)
*
|
2003-08-14 |
2005-03-03 |
Dyax Corp. |
Endotheliase-2 ligands
|
|
EP1515505A1
(en)
*
|
2003-09-12 |
2005-03-16 |
Siemens Aktiengesellschaft |
Reachability maintainance of a moving network based on temporary name identifiers
|
|
US20050136055A1
(en)
*
|
2003-12-22 |
2005-06-23 |
Pfizer Inc |
CD40 antibody formulation and methods
|
|
JP2007526455A
(ja)
*
|
2004-02-03 |
2007-09-13 |
ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン |
癌を特徴付ける、制御する、診断する、および処置するための組成物ならびに方法
|
|
JP2007530526A
(ja)
*
|
2004-03-26 |
2007-11-01 |
ファイザー・プロダクツ・インク |
抗ｃｔｌａ−４抗体の使用
|
|
US7785591B2
(en)
|
2004-10-14 |
2010-08-31 |
Morphosys Ag |
Identification and characterization of function-blocking anti-ED-B-fibronectin antibodies
|
|
KR20070067702A
(ko)
*
|
2004-11-04 |
2007-06-28 |
화이자 프로덕츠 인크. |
유방암을 치료하기 위한 ｃｔｌａ-4 항체와 아로마타제억제제 병용 요법
|
|
TW200719913A
(en)
|
2005-03-08 |
2007-06-01 |
Pharmacia & Upjohn Co Llc |
Anti-madcam antibody compositions
|
|
CN101146553A
(zh)
*
|
2005-03-23 |
2008-03-19 |
辉瑞产品公司 |
用于治疗癌症的抗-ctla4抗体和吲哚酮组合治疗
|
|
AU2006227879A1
(en)
*
|
2005-03-23 |
2006-09-28 |
Pfizer Products Inc. |
Therapy of prostate cancer with CTLA4 antibodies and hormonal therapy
|
|
NZ563193A
(en)
*
|
2005-05-09 |
2010-05-28 |
Ono Pharmaceutical Co |
Human monoclonal antibodies to programmed death 1(PD-1) and methods for treating cancer using anti-PD-1 antibodies alone or in combination with other immunotherapeutics
|
|
SI2397156T1
(sl)
|
2005-06-08 |
2017-06-30 |
Dana-Farber Cancer Institute, Inc. |
Metode in sestavki za zdravljenje trdovratnih okužb in raka z inhibiranjem polipeptida za apoptozo 1 (PD-1)
|
|
EA200800268A1
(ru)
*
|
2005-07-07 |
2008-06-30 |
Коли Фармасьютикал Груп, Инк. |
КОМБИНИРОВАННАЯ ТЕРАПИЯ АНТИТЕЛОМ ПРОТИВ CTLA-4 И СОДЕРЖАЩИМ CpG-МОТИВ СИНТЕТИЧЕСКИМ ОЛИГОДЕЗОКСИНУКЛЕОТИДОМ ДЛЯ ЛЕЧЕНИЯ ЗЛОКАЧЕСТВЕННОЙ ОПУХОЛИ
|
|
US8110194B2
(en)
|
2005-12-07 |
2012-02-07 |
Medarex, Inc. |
CTLA-4 antibody dosage escalation regimens
|
|
EP2007423A2
(en)
*
|
2006-04-05 |
2008-12-31 |
Pfizer Products Incorporated |
Ctla4 antibody combination therapy
|
|
WO2009016449A1
(en)
*
|
2007-07-27 |
2009-02-05 |
Pfizer Limited |
Antibody purification process by precipitation
|
|
KR101666228B1
(ko)
|
2007-09-28 |
2016-10-13 |
인트렉손 코포레이션 |
생물치료학적 분자를 발현시키기 위한 치료학적 유전자-스위치 작제물 및 생물반응기, 및 이의 용도
|
|
RU2373836C2
(ru)
*
|
2007-12-18 |
2009-11-27 |
Федеральное государственное учреждение "Научно-исследовательский институт онкологии имени Н.Н. Петрова Федерального агентства по высокотехнологичной медицинской помощи" |
Способ оптимизации лечебной тактики при лимфоме ходжкина у детей и подростков
|
|
JP2011509299A
(ja)
*
|
2008-01-08 |
2011-03-24 |
ブリストル−マイヤーズ スクイブ カンパニー |
増殖性疾患治療のための、抗ｃｔｌａ−４抗体とチューブリン調節剤との組み合わせ
|
|
US8119129B2
(en)
|
2008-08-01 |
2012-02-21 |
Bristol-Myers Squibb Company |
Combination of anti-CTLA4 antibody with dasatinib for the treatment of proliferative diseases
|
|
ES2768990T3
(es)
*
|
2009-07-20 |
2020-06-24 |
Bristol Myers Squibb Co |
Combinación de anticuerpos anti-CTLA4 con gemcitabina para el tratamiento sinérgico de enfermedades proliferativas
|
|
RU2421217C2
(ru)
*
|
2009-09-03 |
2011-06-20 |
Учреждение Российской академии медицинских наук Гематологический научный центр РАМН (ГНЦ РАМН) |
Способ дифференцированного лечения диффузных в-крупноклеточных лимфосарком лимфоидных органов взрослых
|
|
EP3536708A1
(en)
|
2011-04-19 |
2019-09-11 |
Pfizer Inc |
Combinations of anti-4-1bb antibodies and adcc-inducing antibodies for the treatment of cancer
|
|
ES2572915T3
(es)
|
2011-06-02 |
2016-06-03 |
The University Of Louisville Research Foundation, Inc. |
Nanopartículas conjugadas a un agente antinucleolina
|
|
MX365139B
(es)
|
2012-03-13 |
2019-05-24 |
Hoffmann La Roche |
Uso de una terapia combinada de bevacizumab y paclitaxel en el tratamiento de cáncer de ovario epitelial resistente al platino, carcinoma de las trompas de falopio resistente al platino, o carcinoma peritoneal primario resistente al platino.
|
|
MX376234B
(es)
|
2012-05-04 |
2025-03-07 |
Pfizer |
Anticuerpo anti-ctla-4 como modulador inmune.
|
|
US8968742B2
(en)
*
|
2012-08-23 |
2015-03-03 |
Agensys, Inc. |
Antibody drug conjugates (ADC) that bind to 158P1D7 proteins
|
|
HUE043903T2
(hu)
*
|
2012-12-03 |
2019-09-30 |
Bristol Myers Squibb Co |
Immunmodulációs FC fúziós proteinek rákellenes aktivitásának javítása
|
|
JP6649254B2
(ja)
|
2013-08-08 |
2020-02-19 |
サイチューン ファーマ |
ＩＬ−１５及びＩＬ−１５Ｒαスシドメインに基づくモジュロカイン
|
|
EP3030262B1
(en)
|
2013-08-08 |
2019-10-09 |
Cytune Pharma |
Combined pharmaceutical composition
|
|
KR102338453B1
(ko)
*
|
2013-10-18 |
2021-12-13 |
리제너론 파아마슈티컬스, 인크. |
Ｖｅｇｆ 길항제와 항-ｃｔｌａ-4 항체의 조합물을 포함하는 조성물 및 방법
|
|
JP6712952B2
(ja)
*
|
2014-03-31 |
2020-06-24 |
ザ・ジョンズ・ホプキンス・ユニバーシティー |
固形腫瘍悪性病変を処置するための、抗ｃｔｌａ−４抗体および／または抗ｐｄ−１抗体と組み合わせた、細菌、細菌産物、および他の免疫調節性実体の使用
|
|
WO2015166640A1
(ja)
*
|
2014-05-01 |
2015-11-05 |
株式会社アネロファーマ・サイエンス |
異種ポリペプチド発現カセット
|
|
NZ764826A
(en)
|
2014-05-28 |
2024-09-27 |
Memorial Sloan Kettering Cancer Center |
Anti-gitr antibodies and methods of use thereof
|
|
CN105296433B
(zh)
|
2014-08-01 |
2018-02-09 |
中山康方生物医药有限公司 |
一种ctla4抗体、其药物组合物及其用途
|
|
TR201907471T4
(tr)
|
2014-08-28 |
2019-06-21 |
Halozyme Inc |
Bir hiyalüronan ayrıştırıcı enzim ve bir bağışıklık kontrol noktası inhibitörüyle kombinasyon terapisi.
|
|
US20170248603A1
(en)
|
2014-10-06 |
2017-08-31 |
Dana-Farber Cancer Institute, Inc. |
Angiopoiten-2 biomarkers predictive of anti-immune checkpoint response
|
|
NZ746680A
(en)
|
2014-10-14 |
2020-07-31 |
Halozyme Inc |
Compositions of adenosine deaminase-2 (ada2), variants thereof and methods of using same
|
|
PT3240801T
(pt)
|
2014-12-31 |
2021-02-18 |
Checkmate Pharmaceuticals Inc |
Imunoterapia antitumoral combinada
|
|
AR103675A1
(es)
*
|
2015-02-13 |
2017-05-24 |
Sorrento Therapeutics Inc |
Anticuerpos anti-ctla4 terapéuticos
|
|
CA3020885A1
(en)
|
2015-05-05 |
2016-11-10 |
Mohammad Tariq MALIK |
Anti-nucleolin agent-conjugated nanoparticles as radio-sensitizers and mri and/or x-ray contrast agents
|
|
AU2016271591A1
(en)
*
|
2015-05-29 |
2017-12-21 |
Agenus Inc. |
Anti-CTLA-4 antibodies and methods of use thereof
|
|
US9902772B2
(en)
*
|
2015-07-22 |
2018-02-27 |
Sorrento Therapeutics, Inc. |
Antibody therapeutics that bind LAG3
|
|
US11419934B2
(en)
|
2015-08-18 |
2022-08-23 |
Oncotelic Therapeutics, Inc. |
Use of VDAS to enhance immunomodulating therapies against tumors
|
|
TWI717432B
(zh)
|
2015-12-02 |
2021-02-01 |
美商艾吉納斯公司 |
抗體和使用彼之方法
|
|
WO2017165742A1
(en)
|
2016-03-24 |
2017-09-28 |
Millennium Pharmaceuticals, Inc. |
Methods of treating gastrointestinal immune-related adverse events in anti-ctla4 anti-pd-1 combination treatments
|
|
WO2017165778A1
(en)
|
2016-03-24 |
2017-09-28 |
Millennium Pharmaceuticals, Inc. |
Methods of treating gastrointestinal immune-related adverse events in immune oncology treatments
|
|
WO2017173334A1
(en)
|
2016-04-01 |
2017-10-05 |
Checkmate Pharmaceuticals, Inc. |
Fc receptor-mediated drug delivery
|
|
EA039322B1
(ru)
*
|
2016-04-15 |
2022-01-13 |
Эйдженус Инк. |
Антитела против ctla-4 и способы их применения
|
|
WO2018035710A1
(en)
|
2016-08-23 |
2018-03-01 |
Akeso Biopharma, Inc. |
Anti-ctla4 antibodies
|
|
JP7198666B2
(ja)
*
|
2016-08-26 |
2023-01-04 |
哲治 奥野 |
微小血管血流低減剤およびその利用
|
|
AU2017373944B2
(en)
*
|
2016-12-07 |
2022-02-03 |
Agenus Inc. |
Anti-CTLA-4 antibodies and methods of use thereof
|
|
MA50948A
(fr)
|
2016-12-07 |
2020-10-14 |
Agenus Inc |
Anticorps et procédés d'utilisation de ceux-ci
|
|
US12129299B2
(en)
|
2018-02-02 |
2024-10-29 |
OncoC4, Inc. |
Mutant anti-CTLA-4 antibodies with improved immunotherapeutic effect but attenuated adverse effects
|
|
US12246031B2
(en)
|
2018-02-13 |
2025-03-11 |
Checkmate Pharmaceuticals, Inc. |
Compositions and methods for tumor immunotherapy
|
|
EP3768721A4
(en)
*
|
2018-03-19 |
2021-12-29 |
Wuxi Biologics Ireland Limited. |
Novel anti-ctla-4 antibody polypeptide
|
|
SG11202009647VA
(en)
|
2018-04-09 |
2020-10-29 |
Checkmate Pharmaceuticals |
Packaging oligonucleotides into virus-like particles
|
|
EP3820992A2
(en)
|
2018-07-11 |
2021-05-19 |
Actym Therapeutics, Inc. |
Engineered immunostimulatory bacterial strains and uses thereof
|
|
CN110092826B
(zh)
*
|
2019-02-28 |
2022-04-15 |
天津大学 |
CTLA-4类似物CFN13及CFN13-Fc基因和蛋白
|
|
CN115803343A
(zh)
*
|
2020-05-26 |
2023-03-14 |
百奥泰生物制药股份有限公司 |
多特异性抗体及其应用
|
|
WO2022010537A1
(en)
|
2020-07-10 |
2022-01-13 |
The Regents Of The University Of Michigan |
Gas41 inhibitors and methods of use thereof
|
|
WO2022086852A2
(en)
|
2020-10-19 |
2022-04-28 |
Dana-Farber Cancer Institute, Inc. |
Germline biomarkers of clinical response and benefit to immune checkpoint inhibitor therapy
|
|
EP4326321A1
(en)
|
2021-04-20 |
2024-02-28 |
Institut Curie |
Compositions and methods for use in immunotherapy
|