|
US7109003B2
(en)
|
1998-12-23 |
2006-09-19 |
Abgenix, Inc. |
Methods for expressing and recovering human monoclonal antibodies to CTLA-4
|
|
EE05627B1
(et)
*
|
1998-12-23 |
2013-02-15 |
Pfizer Inc. |
CTLA-4 vastased inimese monoklonaalsed antikehad
|
|
US7605238B2
(en)
|
1999-08-24 |
2009-10-20 |
Medarex, Inc. |
Human CTLA-4 antibodies and their uses
|
|
US7030219B2
(en)
|
2000-04-28 |
2006-04-18 |
Johns Hopkins University |
B7-DC, Dendritic cell co-stimulatory molecules
|
|
US7357928B2
(en)
*
|
2002-04-08 |
2008-04-15 |
University Of Louisville Research Foundation, Inc. |
Method for the diagnosis and prognosis of malignant diseases
|
|
NZ536420A
(en)
*
|
2002-04-12 |
2008-04-30 |
Medarex Inc |
Methods of treatment using CTLA-4 antibodies
|
|
RS52889B
(sr)
|
2002-09-06 |
2014-02-28 |
Amgen Inc |
Terapijsko humano anti-il-1r1 monoklonsko antitelo
|
|
US20040197312A1
(en)
*
|
2003-04-02 |
2004-10-07 |
Marina Moskalenko |
Cytokine-expressing cellular vaccine combinations
|
|
US7465446B2
(en)
|
2003-05-30 |
2008-12-16 |
Medarex, Inc. |
Surrogate therapeutic endpoint for anti-CTLA4-based immunotherapy of disease
|
|
BRPI0411803A
(pt)
|
2003-06-27 |
2006-05-23 |
Abgenix Inc |
anticorpos dirigidos aos mutantes de deleção de receptor de fator de crescimento epidérmico e seus usos
|
|
BRPI0412245A
(pt)
*
|
2003-07-22 |
2006-09-19 |
Schering Ag |
anticorpos de rg1 e usos destes
|
|
US7273610B2
(en)
|
2003-08-14 |
2007-09-25 |
Dyax Corp. |
Endotheliase-2 ligands
|
|
EP1515505A1
(en)
*
|
2003-09-12 |
2005-03-16 |
Siemens Aktiengesellschaft |
Reachability maintainance of a moving network based on temporary name identifiers
|
|
US20050136055A1
(en)
*
|
2003-12-22 |
2005-06-23 |
Pfizer Inc |
CD40 antibody formulation and methods
|
|
CA2554779A1
(en)
*
|
2004-02-03 |
2005-08-18 |
The Regents Of The University Of Michigan |
Compositions and methods for characterizing, regulating, diagnosing, and treating cancer
|
|
BRPI0509274A
(pt)
*
|
2004-03-26 |
2007-09-04 |
Pfizer Prod Inc |
usos de anticorpos anti-ctla-4
|
|
US7785591B2
(en)
|
2004-10-14 |
2010-08-31 |
Morphosys Ag |
Identification and characterization of function-blocking anti-ED-B-fibronectin antibodies
|
|
WO2006048749A1
(en)
*
|
2004-11-04 |
2006-05-11 |
Pfizer Products Inc. |
Ctla-4 antibody and aromatase inhibitor or combination treatment for breast cancer
|
|
BRPI0608815B1
(pt)
|
2005-03-08 |
2021-10-13 |
Pfizer Products Inc |
Composições de anticorpo anti-ctla-4
|
|
JP2006265244A
(ja)
*
|
2005-03-23 |
2006-10-05 |
Pfizer Prod Inc |
Ｃｔｌａ４抗体とホルモン治療を用いた前立腺癌の治療
|
|
NZ561138A
(en)
*
|
2005-03-23 |
2009-06-26 |
Pfizer Prod Inc |
Anti-CTLA4 antibody and indolinone combination therapy for treatment of cancer
|
|
PL2161336T5
(pl)
*
|
2005-05-09 |
2017-10-31 |
Ono Pharmaceutical Co |
Ludzkie przeciwciała monoklonalne przeciwko białku Programmed Death 1 (PD-1) oraz sposoby leczenia raka z zastosowaniem samych przeciwciał anty-PD-1 lub w połączeniu z innymi środkami immunoterapeutycznymi
|
|
DK1907000T4
(da)
|
2005-06-08 |
2020-03-30 |
The President And Fellows Of Harvard College |
Fremgangsmåder og sammensætninger til behandling af persisterende HIV-infektioner ved hæmning af reaktionsvejen for programmeret celledød 1 (PD-1).
|
|
AU2006269555A1
(en)
*
|
2005-07-07 |
2007-01-18 |
Coley Pharmaceutical Group, Inc. |
Anti-CTLA-4 antibody and CpG-motif-containing synthetic oligodeoxynucleotide combination therapy for cancer treatment
|
|
WO2007067959A2
(en)
|
2005-12-07 |
2007-06-14 |
Medarex, Inc. |
Ctla-4 antibody dosage escalation regimens
|
|
CA2647282A1
(en)
*
|
2006-04-05 |
2007-10-11 |
Pfizer Products Inc. |
Ctla4 antibody combination therapy
|
|
EP2176292A1
(en)
*
|
2007-07-27 |
2010-04-21 |
Pfizer Limited |
Antibody purification process by precipitation
|
|
KR101666228B1
(ko)
|
2007-09-28 |
2016-10-13 |
인트렉손 코포레이션 |
생물치료학적 분자를 발현시키기 위한 치료학적 유전자-스위치 작제물 및 생물반응기, 및 이의 용도
|
|
RU2373836C2
(ru)
*
|
2007-12-18 |
2009-11-27 |
Федеральное государственное учреждение "Научно-исследовательский институт онкологии имени Н.Н. Петрова Федерального агентства по высокотехнологичной медицинской помощи" |
Способ оптимизации лечебной тактики при лимфоме ходжкина у детей и подростков
|
|
AU2009204194A1
(en)
*
|
2008-01-08 |
2009-07-16 |
Bristol-Myers Squibb Company |
Combination of anti-CTLA4 antibody with tubulin modulating agents for the treatment of proliferative diseases
|
|
WO2010014784A2
(en)
*
|
2008-08-01 |
2010-02-04 |
Bristol-Myers Squibb Company |
Combination of anti-ctla4 antibody with diverse therapeutic regimens for the synergistic treatment of proliferative diseases
|
|
CN102822200A
(zh)
*
|
2009-07-20 |
2012-12-12 |
百时美施贵宝公司 |
对增殖性疾病进行协同性治疗的抗ctla-4抗体与各种治疗方案的组合
|
|
RU2421217C2
(ru)
*
|
2009-09-03 |
2011-06-20 |
Учреждение Российской академии медицинских наук Гематологический научный центр РАМН (ГНЦ РАМН) |
Способ дифференцированного лечения диффузных в-крупноклеточных лимфосарком лимфоидных органов взрослых
|
|
WO2012145183A2
(en)
|
2011-04-19 |
2012-10-26 |
Pfizer Inc. |
Combinations of anti-4-1bb antibodies and adcc-inducing antibodies for the treatment of cancer
|
|
ES2690557T3
(es)
|
2011-06-02 |
2018-11-21 |
University Of Louisville Research Foundation, Inc. |
Nanopartículas conjugadas a un agente antinucleolina
|
|
PT2825558T
(pt)
|
2012-03-13 |
2019-07-11 |
Hoffmann La Roche |
Terapêutica combinada para o tratamento do cancro do ovário
|
|
KR101728483B1
(ko)
|
2012-05-04 |
2017-04-19 |
화이자 인코포레이티드 |
전립선 관련된 항원 및 백신 기재 면역치료 요법
|
|
AR092219A1
(es)
*
|
2012-08-23 |
2015-04-08 |
Seattle Genetics Inc |
Conjugados anticuerpo-farmaco (adc) que se unen a proteinas 158p1d7
|
|
SMT201900242T1
(it)
*
|
2012-12-03 |
2019-05-10 |
Bristol Myers Squibb Co |
Incremento dell'attivita' anti-cancro di proteine di fuzione a fc immunomodulatrici
|
|
DK3030575T3
(en)
|
2013-08-08 |
2018-10-22 |
Cytune Pharma |
IL-15 AND IL-15R-ALFA-SUSHI DOMAIN-BASED MODULOKINES
|
|
ES2760249T3
(es)
|
2013-08-08 |
2020-05-13 |
Cytune Pharma |
Composición farmacéutica combinada
|
|
EA037890B1
(ru)
*
|
2013-10-18 |
2021-06-01 |
Ридженерон Фармасьютикалз, Инк. |
Способы и композиции, включающие комбинацию антагониста vegf и анти-ctla-4 антитела
|
|
JP6712952B2
(ja)
*
|
2014-03-31 |
2020-06-24 |
ザ・ジョンズ・ホプキンス・ユニバーシティー |
固形腫瘍悪性病変を処置するための、抗ｃｔｌａ−４抗体および／または抗ｐｄ−１抗体と組み合わせた、細菌、細菌産物、および他の免疫調節性実体の使用
|
|
SG10201809450VA
(en)
*
|
2014-05-01 |
2018-11-29 |
Anaeropharma Science Inc |
Heterogeneous polypeptide expression cassette
|
|
EA201692458A1
(ru)
|
2014-05-28 |
2017-06-30 |
Агенус Инк. |
Анти-gitr антитела и способы их применения
|
|
CN105296433B
(zh)
|
2014-08-01 |
2018-02-09 |
中山康方生物医药有限公司 |
一种ctla4抗体、其药物组合物及其用途
|
|
WO2016033555A1
(en)
|
2014-08-28 |
2016-03-03 |
Halozyme, Inc. |
Combination therapy with a hyaluronan-degrading enzyme and an immune checkpoint inhibitor
|
|
US20170248603A1
(en)
|
2014-10-06 |
2017-08-31 |
Dana-Farber Cancer Institute, Inc. |
Angiopoiten-2 biomarkers predictive of anti-immune checkpoint response
|
|
CA2964317C
(en)
|
2014-10-14 |
2021-10-05 |
Halozyme, Inc. |
Compositions of adenosine deaminase-2 (ada2), variants thereof and methods of using same
|
|
CA2972757A1
(en)
|
2014-12-31 |
2016-07-07 |
Arthur M. Krieg |
Combination tumor immunotherapy
|
|
WO2016130986A1
(en)
*
|
2015-02-13 |
2016-08-18 |
Sorrento Therapeutics, Inc. |
Antibody therapeutics that bind ctla4
|
|
WO2016179394A1
(en)
|
2015-05-05 |
2016-11-10 |
Malik Mohammad Tariq |
Anti-nucleolin agent-conjugated nanoparticles as radio-sensitizers and mri and/or x-ray contrast agents
|
|
EP3303394B1
(en)
|
2015-05-29 |
2020-04-08 |
Agenus Inc. |
Anti-ctla-4 antibodies and methods of use thereof
|
|
CA2993177A1
(en)
*
|
2015-07-22 |
2017-01-26 |
Sorrento Therapeutics, Inc. |
Antibody therapeutics that bind lag3
|
|
US11419934B2
(en)
*
|
2015-08-18 |
2022-08-23 |
Oncotelic Therapeutics, Inc. |
Use of VDAS to enhance immunomodulating therapies against tumors
|
|
AU2016364889B2
(en)
|
2015-12-02 |
2024-01-04 |
Agenus Inc. |
Antibodies and methods of use thereof
|
|
WO2017165742A1
(en)
|
2016-03-24 |
2017-09-28 |
Millennium Pharmaceuticals, Inc. |
Methods of treating gastrointestinal immune-related adverse events in anti-ctla4 anti-pd-1 combination treatments
|
|
US11760803B2
(en)
|
2016-03-24 |
2023-09-19 |
Takeda Pharmaceutical Company Limited |
Methods of treating gastrointestinal immune-related adverse events in immune oncology treatments
|
|
US20190046638A1
(en)
|
2016-04-01 |
2019-02-14 |
Checkmate Pharmaceuticals, Inc. |
Fc RECEPTOR-MEDIATED DRUG DELIVERY
|
|
EA039322B1
(ru)
*
|
2016-04-15 |
2022-01-13 |
Эйдженус Инк. |
Антитела против ctla-4 и способы их применения
|
|
WO2018035710A1
(en)
|
2016-08-23 |
2018-03-01 |
Akeso Biopharma, Inc. |
Anti-ctla4 antibodies
|
|
JP7198666B2
(ja)
*
|
2016-08-26 |
2023-01-04 |
哲治 奥野 |
微小血管血流低減剤およびその利用
|
|
EP3551225A1
(en)
|
2016-12-07 |
2019-10-16 |
Agenus Inc. |
Antibodies and methods of use thereof
|
|
KR102504605B1
(ko)
|
2016-12-07 |
2023-03-02 |
아게누스 인코포레이티드 |
항-ctla-4 항체 및 이의 사용 방법
|
|
JP7490923B2
(ja)
|
2018-02-02 |
2024-05-28 |
オンコシーフォー、インク． |
免疫療法効果が向上し副作用が軽減した変異抗ｃｔｌａ－４抗体
|
|
US12246031B2
(en)
|
2018-02-13 |
2025-03-11 |
Checkmate Pharmaceuticals, Inc. |
Compositions and methods for tumor immunotherapy
|
|
CN112218892B
(zh)
*
|
2018-03-19 |
2023-04-25 |
上海药明生物技术有限公司 |
新型抗ctla-4抗体多肽
|
|
EP3775218A1
(en)
|
2018-04-09 |
2021-02-17 |
Checkmate Pharmaceuticals |
Packaging oligonucleotides into virus-like particles
|
|
AU2019301699C1
(en)
|
2018-07-11 |
2024-10-10 |
Actym Therapeutics, Inc. |
Engineered immunostimulatory bacterial strains and uses thereof
|
|
CN110092826B
(zh)
*
|
2019-02-28 |
2022-04-15 |
天津大学 |
CTLA-4类似物CFN13及CFN13-Fc基因和蛋白
|
|
WO2021238932A1
(zh)
*
|
2020-05-26 |
2021-12-02 |
百奥泰生物制药股份有限公司 |
多特异性抗体及其应用
|
|
US11858925B2
(en)
|
2020-07-10 |
2024-01-02 |
The Regents Of The University Of Michigan |
GAS41 inhibitors and methods of use thereof
|
|
WO2022086852A2
(en)
|
2020-10-19 |
2022-04-28 |
Dana-Farber Cancer Institute, Inc. |
Germline biomarkers of clinical response and benefit to immune checkpoint inhibitor therapy
|
|
JP2024517131A
(ja)
|
2021-04-20 |
2024-04-19 |
アンスティテュ・クリー |
免疫療法における使用のための組成物及び方法
|