PL3157552T3 - Polipeptydy syntac i ich zastosowania - Google Patents
Polipeptydy syntac i ich zastosowaniaInfo
- Publication number
- PL3157552T3 PL3157552T3 PL15809277T PL15809277T PL3157552T3 PL 3157552 T3 PL3157552 T3 PL 3157552T3 PL 15809277 T PL15809277 T PL 15809277T PL 15809277 T PL15809277 T PL 15809277T PL 3157552 T3 PL3157552 T3 PL 3157552T3
- Authority
- PL
- Poland
- Prior art keywords
- syntac polypeptides
- syntac
- polypeptides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462013715P | 2014-06-18 | 2014-06-18 | |
EP15809277.5A EP3157552B1 (en) | 2014-06-18 | 2015-06-15 | Syntac polypeptides and uses thereof |
PCT/US2015/035777 WO2015195531A2 (en) | 2014-06-18 | 2015-06-15 | Syntac polypeptides and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
PL3157552T3 true PL3157552T3 (pl) | 2020-05-18 |
Family
ID=54936224
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL18212801T PL3480213T3 (pl) | 2014-06-18 | 2015-06-15 | Polipeptydy syntac i ich zastosowania |
PL15809277T PL3157552T3 (pl) | 2014-06-18 | 2015-06-15 | Polipeptydy syntac i ich zastosowania |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL18212801T PL3480213T3 (pl) | 2014-06-18 | 2015-06-15 | Polipeptydy syntac i ich zastosowania |
Country Status (17)
Country | Link |
---|---|
US (5) | US20170058015A1 (pl) |
EP (3) | EP3480213B1 (pl) |
JP (4) | JP6652932B2 (pl) |
KR (1) | KR102252119B1 (pl) |
CN (3) | CN106456733B (pl) |
AU (3) | AU2015277460B2 (pl) |
BR (1) | BR112016027897A2 (pl) |
CA (1) | CA2947489A1 (pl) |
DK (2) | DK3157552T3 (pl) |
ES (2) | ES2767259T3 (pl) |
HU (2) | HUE048076T2 (pl) |
IL (3) | IL248979B (pl) |
PL (2) | PL3480213T3 (pl) |
PT (2) | PT3480213T (pl) |
SG (2) | SG10202006338UA (pl) |
TW (3) | TWI795740B (pl) |
WO (1) | WO2015195531A2 (pl) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10048271B2 (en) | 2012-12-11 | 2018-08-14 | Albert Einstein College Of Medicine, Inc. | Methods for high throughput receptor:ligand identification |
KR20180132663A (ko) * | 2016-03-02 | 2018-12-12 | 큐 바이오파마, 인크. | T-세포 조절 다량체 폴리펩타이드 및 이의 사용 방법 |
EP3423078A4 (en) * | 2016-03-03 | 2019-11-06 | Cue Biopharma, Inc. | T CELL MODULATING MULTIPLE POLYPEPTIDES AND METHOD OF USE THEREOF |
EP3458096A4 (en) * | 2016-05-18 | 2019-11-27 | Cue Biopharma, Inc. | T-LYMPHOCYTE MODULATOR MULTIMERIC POLYPEPTIDES AND METHODS OF USE |
CA3022331A1 (en) * | 2016-05-18 | 2017-11-23 | Albert Einstein College Of Medicine, Inc. | Variant pd-l1 polypeptides, t-cell modulatory multimeric polypeptides, and methods of use thereof |
US11725041B2 (en) | 2016-08-11 | 2023-08-15 | The Council Of The Queensland Institute Of Medical Research | Immune-modulating compounds |
CN110325205B (zh) * | 2016-12-22 | 2023-08-15 | 库尔生物制药有限公司 | T细胞调节性多聚体多肽及其使用方法 |
WO2018129474A1 (en) | 2017-01-09 | 2018-07-12 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
CA3054955A1 (en) * | 2017-03-15 | 2018-09-20 | Cue Biopharma, Inc. | Methods for modulating an immune response |
US11407806B2 (en) | 2017-04-06 | 2022-08-09 | Albert Einstein College Of Medicine | Precision activation of HIV-specific CTLS to eliminate reactivated latent T cells |
KR20200016954A (ko) * | 2017-06-12 | 2020-02-17 | 시나이 헬스 시스템 | 전신 면역억제가 불필요한 동종 이식편 내성 |
CN107266581B (zh) * | 2017-06-13 | 2021-07-09 | 四川大学 | 藏猪il-12重组质粒增强pcv2疫苗免疫佐剂的制备方法及应用 |
WO2019051126A1 (en) * | 2017-09-07 | 2019-03-14 | Cue Biopharma, Inc. | ANTIGEN PRESENTING POLYPEPTIDES COMPRISING CHEMICAL CONJUGATION SITES AND METHODS OF USE THEREOF |
WO2019051091A1 (en) * | 2017-09-07 | 2019-03-14 | Cue Biopharma, Inc. | T-LYMPHOCYTE MODULATOR MULTIMERIC POLYPEPTIDES AND METHODS OF USE THEREOF |
JP2021500855A (ja) * | 2017-09-07 | 2021-01-14 | キュー バイオファーマ, インコーポレイテッド | 抗原提示ポリペプチドおよびその使用方法 |
AU2018327224A1 (en) | 2017-09-07 | 2020-04-23 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptide with conjugation sites and methods of use thereof |
KR20210035915A (ko) * | 2017-11-30 | 2021-04-01 | 그리폴스 다이어그노스틱 솔루션즈 인크. | 면역 관문 억제제인 pd-1 및 pd-l1에 대한 항체 치료를 모니터링하기 위한 면역분석 및 조작된 단백질 |
CN111886241A (zh) | 2018-01-09 | 2020-11-03 | 库尔生物制药有限公司 | 多聚体t细胞调节多肽及其使用方法 |
CA3093995A1 (en) | 2018-03-24 | 2019-10-03 | Regeneron Pharmaceuticals, Inc. | Genetically modified non-human animals for generating therapeutic antibodies against peptide-mhc complexes, methods of making and uses thereof |
WO2020056152A1 (en) * | 2018-09-12 | 2020-03-19 | Chang Liu | Single chain constructs |
TW202039542A (zh) * | 2018-12-19 | 2020-11-01 | 美商庫爾生物製藥有限公司 | 多聚體t細胞調節多肽及其使用方法 |
CA3113096A1 (en) * | 2018-12-19 | 2020-06-25 | Cue Biopharma, Inc. | Multimeric t-cell modulatory polypeptides and methods of use thereof |
WO2020132368A1 (en) * | 2018-12-19 | 2020-06-25 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides with conjugation sites and methods of use thereof |
WO2020180501A1 (en) * | 2019-03-06 | 2020-09-10 | Cue Biopharma, Inc. | T-cell modulatory antigen-presenting polypeptides and methods of use thereof |
AU2020282736A1 (en) * | 2019-05-29 | 2021-10-28 | Cue Biopharma, Inc. | Multimeric T-cell modulatory polypeptides and methods of use thereof |
JP2022536581A (ja) * | 2019-06-19 | 2022-08-18 | キュー バイオファーマ, インコーポレイテッド | 多量体t細胞調節性ポリペプチド及びその使用方法 |
MX2022003367A (es) * | 2019-09-20 | 2022-04-11 | Cue Biopharma Inc | Polipeptidos moduladores de linfocitos t y metodos de uso de estos. |
AU2020370292A1 (en) * | 2019-10-23 | 2022-03-03 | Cue Biopharma, Inc. | T-cell modulatory chimeric molecules and methods of use thereof |
CN115023444A (zh) | 2019-12-20 | 2022-09-06 | 再生元制药公司 | 新型il2激动剂及其使用方法 |
WO2021168122A1 (en) * | 2020-02-18 | 2021-08-26 | Institute For Systems Biology | Single chain trimer mhc class ii nucleic acids and proteins and methods of use |
US20230212259A1 (en) * | 2020-02-21 | 2023-07-06 | 3T Biosciences, Inc. | Yeast display libraries, associated compositions, and associate methods of use |
WO2021178975A1 (en) * | 2020-03-06 | 2021-09-10 | Albert Einstein College Of Medicine | A method to generate chimeric antigen receptor (car) t-cells (car-t cells) from pathogen-specific cytotoxic lymphocytes to enable the subsequent in vivo modulation of their functional activity |
EP4149953A1 (en) * | 2020-05-12 | 2023-03-22 | Lg Chem, Ltd. | Multimeric t-cell modulatory polypeptides and methods of use thereof |
WO2021231376A2 (en) | 2020-05-12 | 2021-11-18 | Cue Biopharma, Inc. | Multimeric t-cell modulatory polypeptides and methods of use thereof |
CN112852744A (zh) * | 2021-01-27 | 2021-05-28 | 河南省华隆生物技术有限公司 | 一种nk滋养层细胞及其制备方法和应用 |
CN112725284A (zh) * | 2021-01-27 | 2021-04-30 | 河南省华隆生物技术有限公司 | 一种nk滋养层细胞及其应用 |
CN112779224A (zh) * | 2021-01-27 | 2021-05-11 | 河南省华隆生物技术有限公司 | 一种表达细胞因子组合物的nk滋养层细胞及其制备方法和应用 |
CN112725273A (zh) * | 2021-01-27 | 2021-04-30 | 河南省华隆生物技术有限公司 | 一种nk细胞及其制备方法和应用 |
CA3215077A1 (en) * | 2021-04-07 | 2022-10-13 | Thomas J. Malia | Peptide-mhc-immunoglobulin multimers and methods of use thereof |
EP4334453A1 (en) * | 2021-05-07 | 2024-03-13 | Institute for Systems Biology | Single chain trimer mhc class i nucleic acids and proteins and methods of use |
US20230110958A1 (en) | 2021-08-16 | 2023-04-13 | Regeneron Pharmaceuticals, Inc. | Il27 receptor agonists and methods of use thereof |
WO2023126544A1 (en) * | 2022-01-03 | 2023-07-06 | Aarhus Universitet | Proteinaceous compound for generating specific cytotoxic t-cell effect |
WO2023205728A2 (en) * | 2022-04-21 | 2023-10-26 | Institute For Systems Biology | Soluble single-chain dimers from cleavable single chain trimers |
WO2023240109A1 (en) | 2022-06-07 | 2023-12-14 | Regeneron Pharmaceuticals, Inc. | Multispecific molecules for modulating t-cell activity, and uses thereof |
WO2023240124A1 (en) | 2022-06-07 | 2023-12-14 | Regeneron Pharmaceuticals, Inc. | Pseudotyped viral particles for targeting tcr-expressing cells |
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EP1024198A3 (en) | 1992-12-03 | 2002-05-29 | Genzyme Corporation | Pseudo-adenoviral vectors for the gene therapy of haemophiliae |
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US6211342B1 (en) * | 1996-07-18 | 2001-04-03 | Children's Hospital Medical Center | Multivalent MHC complex peptide fusion protein complex for stimulating specific T cell function |
US20050003431A1 (en) * | 1996-08-16 | 2005-01-06 | Wucherpfennig Kai W. | Monovalent, multivalent, and multimeric MHC binding domain fusion proteins and conjugates, and uses therefor |
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CA2440773A1 (en) * | 2001-03-14 | 2002-09-19 | Dakocytomation Denmark A/S | Novel mhc molecule constructs, and methods of employing these constructs for diagnosis and therapy, and uses of mhc molecules |
DE102004014983A1 (de) * | 2004-03-26 | 2005-10-20 | Univ Stuttgart | Rekombinante Polypeptide der Mitglieder der TNF Ligandenfamilie und deren Verwendung |
US7670595B2 (en) * | 2004-06-28 | 2010-03-02 | Merck Patent Gmbh | Fc-interferon-beta fusion proteins |
WO2007103515A2 (en) | 2006-03-06 | 2007-09-13 | Amunix, Inc. | Unstructured recombinant polymers and uses thereof |
US7855279B2 (en) | 2005-09-27 | 2010-12-21 | Amunix Operating, Inc. | Unstructured recombinant polymers and uses thereof |
US8518697B2 (en) * | 2006-04-04 | 2013-08-27 | Washington University | Single chain trimers and uses therefor |
EP2361930A3 (en) * | 2007-03-26 | 2011-10-26 | Dako Denmark A/S | Multimers of MHC-peptide complexes and uses thereof in Borrelia infectious diseases |
AU2008287340A1 (en) * | 2007-08-15 | 2009-02-19 | Amunix, Inc. | Compositions and methods for modifying properties of biologically active polypeptides |
WO2010037395A2 (en) * | 2008-10-01 | 2010-04-08 | Dako Denmark A/S | Mhc multimers in cancer vaccines and immune monitoring |
PT2393828T (pt) * | 2009-02-03 | 2017-01-18 | Amunix Operating Inc | Polipéptidos recombinantes estendidos e composições que compreendem os mesmos |
US8956619B2 (en) * | 2011-10-25 | 2015-02-17 | University Of Maryland, Baltimore County | Soluble CD80 as a therapeutic to reverse immune supression in cancer patients |
RU2015125639A (ru) * | 2012-11-30 | 2017-01-10 | Роше Гликарт Аг | Удаление раковых клеток с помощью циркулирующих вирус-специфических цитотоксических т-клеток с использованием направленных против раковых клеток многофункциональных белков, содержащих молекулу гкгс класса i |
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2015
- 2015-06-15 ES ES15809277T patent/ES2767259T3/es active Active
- 2015-06-15 PL PL18212801T patent/PL3480213T3/pl unknown
- 2015-06-15 US US15/306,678 patent/US20170058015A1/en not_active Abandoned
- 2015-06-15 DK DK15809277.5T patent/DK3157552T3/da active
- 2015-06-15 CN CN201580027510.0A patent/CN106456733B/zh active Active
- 2015-06-15 SG SG10202006338UA patent/SG10202006338UA/en unknown
- 2015-06-15 PT PT182128017T patent/PT3480213T/pt unknown
- 2015-06-15 JP JP2016565693A patent/JP6652932B2/ja active Active
- 2015-06-15 CA CA2947489A patent/CA2947489A1/en active Pending
- 2015-06-15 HU HUE18212801A patent/HUE048076T2/hu unknown
- 2015-06-15 BR BR112016027897A patent/BR112016027897A2/pt active Search and Examination
- 2015-06-15 CN CN202110210461.1A patent/CN113248624A/zh active Pending
- 2015-06-15 WO PCT/US2015/035777 patent/WO2015195531A2/en active Application Filing
- 2015-06-15 EP EP18212801.7A patent/EP3480213B1/en active Active
- 2015-06-15 EP EP15809277.5A patent/EP3157552B1/en active Active
- 2015-06-15 PT PT158092775T patent/PT3157552T/pt unknown
- 2015-06-15 CN CN202110210453.7A patent/CN113248623A/zh active Pending
- 2015-06-15 HU HUE15809277A patent/HUE047255T2/hu unknown
- 2015-06-15 EP EP18212805.8A patent/EP3483179B1/en active Active
- 2015-06-15 SG SG11201609876TA patent/SG11201609876TA/en unknown
- 2015-06-15 PL PL15809277T patent/PL3157552T3/pl unknown
- 2015-06-15 DK DK18212801.7T patent/DK3480213T3/da active
- 2015-06-15 KR KR1020167034341A patent/KR102252119B1/ko active IP Right Grant
- 2015-06-15 ES ES18212801T patent/ES2770330T3/es active Active
- 2015-06-15 AU AU2015277460A patent/AU2015277460B2/en active Active
- 2015-06-17 TW TW110108178A patent/TWI795740B/zh active
- 2015-06-17 TW TW104119612A patent/TWI696633B/zh active
- 2015-06-17 TW TW108133859A patent/TWI722576B/zh active
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2016
- 2016-11-15 IL IL248979A patent/IL248979B/en active IP Right Grant
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2018
- 2018-06-06 US US16/001,153 patent/US20180282392A1/en not_active Abandoned
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2019
- 2019-05-12 IL IL266570A patent/IL266570B/en active IP Right Grant
- 2019-05-16 AU AU2019203442A patent/AU2019203442B2/en active Active
- 2019-10-23 JP JP2019192453A patent/JP6652680B2/ja active Active
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2020
- 2020-01-13 US US16/740,752 patent/US20200377569A1/en not_active Abandoned
- 2020-01-24 JP JP2020009921A patent/JP6995151B2/ja active Active
- 2020-06-11 IL IL275307A patent/IL275307B/en unknown
- 2020-08-25 US US17/001,847 patent/US20210238254A1/en active Pending
- 2020-09-09 US US17/015,282 patent/US20210047384A1/en active Pending
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2021
- 2021-07-01 AU AU2021204594A patent/AU2021204594A1/en active Pending
- 2021-12-14 JP JP2021202405A patent/JP7331075B2/ja active Active
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