PL3103866T3 - Sposób atenuowania świńskiego wirusa wścieklizny rzekomej, szczepy wirusowe atenuowane w ten sposób, kompozycja szczepionki i jej zastosowanie - Google Patents
Sposób atenuowania świńskiego wirusa wścieklizny rzekomej, szczepy wirusowe atenuowane w ten sposób, kompozycja szczepionki i jej zastosowanieInfo
- Publication number
- PL3103866T3 PL3103866T3 PL15853631T PL15853631T PL3103866T3 PL 3103866 T3 PL3103866 T3 PL 3103866T3 PL 15853631 T PL15853631 T PL 15853631T PL 15853631 T PL15853631 T PL 15853631T PL 3103866 T3 PL3103866 T3 PL 3103866T3
- Authority
- PL
- Poland
- Prior art keywords
- application
- vaccine composition
- pseudorabies virus
- viral strains
- porcine pseudorabies
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
- C12N7/08—Inactivation or attenuation by serial passage of virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16761—Methods of inactivation or attenuation
- C12N2710/16764—Methods of inactivation or attenuation by serial passage
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- General Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510124250.0A CN105087506B (zh) | 2015-03-20 | 2015-03-20 | 一种猪伪狂犬病病毒致弱方法、及其致弱的病毒株、疫苗组合物和应用 |
EP15853631.8A EP3103866B1 (en) | 2015-03-20 | 2015-07-06 | Porcine pseudorabies virus attenuating method, viral strains attenuated thereby, vaccine composition and application thereof |
PCT/CN2015/083354 WO2016150026A1 (zh) | 2015-03-20 | 2015-07-06 | 一种猪伪狂犬病病毒致弱方法、及其致弱的病毒株、疫苗组合物和应用 |
Publications (1)
Publication Number | Publication Date |
---|---|
PL3103866T3 true PL3103866T3 (pl) | 2022-01-31 |
Family
ID=54568841
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL15853631T PL3103866T3 (pl) | 2015-03-20 | 2015-07-06 | Sposób atenuowania świńskiego wirusa wścieklizny rzekomej, szczepy wirusowe atenuowane w ten sposób, kompozycja szczepionki i jej zastosowanie |
Country Status (7)
Country | Link |
---|---|
US (2) | US9795667B2 (pl) |
EP (1) | EP3103866B1 (pl) |
JP (1) | JP6325106B2 (pl) |
CN (2) | CN105087506B (pl) |
HU (1) | HUE057101T2 (pl) |
PL (1) | PL3103866T3 (pl) |
WO (1) | WO2016150026A1 (pl) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105087506B (zh) * | 2015-03-20 | 2020-06-30 | 普莱柯生物工程股份有限公司 | 一种猪伪狂犬病病毒致弱方法、及其致弱的病毒株、疫苗组合物和应用 |
CN105602909A (zh) * | 2016-03-29 | 2016-05-25 | 四川海林格生物制药有限公司 | 一种猪伪狂犬病毒的培养方法 |
CN107537034B (zh) * | 2016-06-28 | 2020-11-10 | 普莱柯生物工程股份有限公司 | 猪繁殖与呼吸综合征、猪伪狂犬病二联活疫苗及其制备方法和应用 |
CN108251383A (zh) * | 2016-12-29 | 2018-07-06 | 普莱柯生物工程股份有限公司 | 一种猪伪狂犬病病毒致弱方法、及其致弱的病毒株、疫苗组合物和应用 |
CN107137705B (zh) * | 2017-05-08 | 2018-01-23 | 广东渔跃生物技术有限公司 | 猪伪狂犬gE基因缺失病毒灭活疫苗的生产方法 |
CN107267470A (zh) * | 2017-08-08 | 2017-10-20 | 中国农业大学 | 一种猪伪狂犬病毒基因缺失株C1201/ΔgE株及其应用 |
CN107653230A (zh) * | 2017-08-31 | 2018-02-02 | 浙江大学 | 一种ⅱ型伪狂犬病毒毒株及其应用 |
CN110257274B (zh) * | 2019-05-15 | 2023-02-28 | 西北农林科技大学 | 一种伪结核棒状杆菌致弱方法及应用 |
CN110387354B (zh) * | 2019-08-16 | 2022-11-08 | 江苏省农业科学院 | 伪狂犬病病毒传代致弱毒株及其应用 |
CN111154917B (zh) * | 2020-02-22 | 2022-12-27 | 南京农业大学 | 鉴别猪伪狂犬病毒变异毒株的pcr引物及方法 |
CN111826339A (zh) * | 2020-05-26 | 2020-10-27 | 成都天邦生物制品有限公司 | 一株Vero单克隆细胞系及其应用 |
CN112342201B (zh) * | 2020-11-04 | 2023-01-03 | 武汉科前生物股份有限公司 | 一种通过CRISPR/Cas9制备的猪伪狂犬病弱毒株及其应用 |
CN113425839B (zh) * | 2021-06-04 | 2023-11-21 | 天康制药股份有限公司 | 猪伪狂犬病、猪支原体肺炎二联灭活疫苗及其制备方法 |
CN114989306B (zh) * | 2022-04-29 | 2023-04-18 | 重庆市动物疫病预防控制中心 | 一种猪伪狂犬病毒gE和gI纳米抗体、制备方法和应用 |
CN117384863B (zh) * | 2023-10-18 | 2024-04-05 | 武汉科前生物股份有限公司 | 猪伪狂犬病病毒自然传代弱毒变异株js18-150及其应用 |
Family Cites Families (21)
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SE8205892D0 (sv) | 1982-10-18 | 1982-10-18 | Bror Morein | Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin |
US5047237A (en) * | 1985-09-06 | 1991-09-10 | Prutech Research And Development Partnership | Attenuated pseudorabies virus having a deletion of at least a portion of a gene encoding an antigenic, nonessential protein, vaccine containing same and methods of identifying animals vaccinated with the vaccine |
US5695765A (en) * | 1989-08-17 | 1997-12-09 | Stichting Voor De Technische Wetenschappen | Mutant pseudorabies virus, and vaccines containing the same |
US5240703A (en) * | 1991-03-01 | 1993-08-31 | Syntro Corporation | Attenuated, genetically-engineered pseudorabies virus s-prv-155 and uses thereof |
TW289731B (pl) * | 1992-07-09 | 1996-11-01 | Akzo Nv | |
IT1269739B (it) * | 1994-05-10 | 1997-04-15 | Fatro Spa | Stipite virale contro la pseudorabbia del suino e vaccinicontenenti il detto virus |
FR2781159B1 (fr) * | 1998-07-06 | 2000-10-06 | Merial Sas | Vaccin circovirus et parvovirus porcin |
CN1244692C (zh) * | 2003-09-08 | 2006-03-08 | 华中农业大学 | 一种伪狂犬病TK-/gE-/gI-基因缺失标志活疫苗及制备方法 |
CA2894069C (en) * | 2005-06-24 | 2019-02-26 | Regents Of The University Of Minnesota | Prrs viruses, infectious clones, mutants thereof, and methods of use |
CN101695573B (zh) * | 2009-10-26 | 2013-09-11 | 广东永顺生物制药股份有限公司 | 一种用传代细胞源生产伪狂犬病活疫苗的方法及其制品 |
CN101804203A (zh) * | 2010-05-10 | 2010-08-18 | 洛阳普莱柯生物工程有限公司 | 一种大规模生产伪狂犬病毒疫苗的方法 |
CA2837125A1 (en) * | 2011-05-27 | 2012-12-06 | Sinovet (Beijing) Biotechnology Co.,Ltd | Combined vaccines for prevention of porcine virus infections |
CN102399755B (zh) * | 2011-09-21 | 2013-03-20 | 上海创宏生物科技有限公司 | 一种猪伪狂犬病毒天然弱毒株c株及其耐热保存方法 |
JP6386999B2 (ja) * | 2012-05-17 | 2018-09-05 | ゾエティス・エルエルシー | ブタ生殖および呼吸症候群(prrs)ウイルスに対する離乳前の効果的なワクチン接種 |
CN102994458B (zh) | 2012-11-26 | 2014-04-02 | 中国农业科学院哈尔滨兽医研究所 | 猪伪狂犬病病毒强毒株、其基因缺失疫苗株及其应用 |
CN102988974B (zh) * | 2012-12-14 | 2015-05-20 | 山东滨州沃华生物工程有限公司 | 一种用传代鸡胚成纤维细胞制备猪伪狂犬活疫苗的方法 |
CN103865886A (zh) * | 2012-12-18 | 2014-06-18 | 青岛中仁药业有限公司 | 猪伪狂犬病毒的培养方法 |
EP2985288B1 (en) * | 2013-05-31 | 2019-11-13 | Pulike Biological Engineering, Inc. | Porcine pseudorabies virus, vaccine composition and preparation method and use thereof |
CN103627678B (zh) | 2013-12-19 | 2016-03-02 | 姜平 | 一种猪伪狂犬病病毒变异株prv-zj01及应用 |
CN104250640A (zh) * | 2014-08-22 | 2014-12-31 | 普莱柯生物工程股份有限公司 | 猪伪狂犬病病毒基因缺失株、疫苗组合物及其制备方法和应用 |
CN105087506B (zh) * | 2015-03-20 | 2020-06-30 | 普莱柯生物工程股份有限公司 | 一种猪伪狂犬病病毒致弱方法、及其致弱的病毒株、疫苗组合物和应用 |
-
2015
- 2015-03-20 CN CN201510124250.0A patent/CN105087506B/zh active Active
- 2015-03-20 CN CN202010451096.9A patent/CN111560355A/zh active Pending
- 2015-07-06 WO PCT/CN2015/083354 patent/WO2016150026A1/zh active Application Filing
- 2015-07-06 PL PL15853631T patent/PL3103866T3/pl unknown
- 2015-07-06 HU HUE15853631A patent/HUE057101T2/hu unknown
- 2015-07-06 JP JP2016536983A patent/JP6325106B2/ja active Active
- 2015-07-06 EP EP15853631.8A patent/EP3103866B1/en active Active
- 2015-07-06 US US15/030,345 patent/US9795667B2/en active Active
-
2016
- 2016-07-19 US US15/213,711 patent/US9801936B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CN105087506A (zh) | 2015-11-25 |
EP3103866A1 (en) | 2016-12-14 |
US9795667B2 (en) | 2017-10-24 |
US9801936B2 (en) | 2017-10-31 |
HUE057101T2 (hu) | 2022-04-28 |
JP2017512455A (ja) | 2017-05-25 |
CN111560355A (zh) | 2020-08-21 |
JP6325106B2 (ja) | 2018-05-16 |
CN105087506B (zh) | 2020-06-30 |
EP3103866B1 (en) | 2021-09-08 |
US20160317651A1 (en) | 2016-11-03 |
US20160279231A1 (en) | 2016-09-29 |
EP3103866A4 (en) | 2017-10-04 |
WO2016150026A1 (zh) | 2016-09-29 |
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