PL2913394T3 - Wspólne różnicowanie i aktywowanie monocytów od dawców allogenicznych dla dostarczenia prozapalnych komórek dendrytycznych - Google Patents
Wspólne różnicowanie i aktywowanie monocytów od dawców allogenicznych dla dostarczenia prozapalnych komórek dendrytycznychInfo
- Publication number
- PL2913394T3 PL2913394T3 PL15161369.2T PL15161369T PL2913394T3 PL 2913394 T3 PL2913394 T3 PL 2913394T3 PL 15161369 T PL15161369 T PL 15161369T PL 2913394 T3 PL2913394 T3 PL 2913394T3
- Authority
- PL
- Poland
- Prior art keywords
- monocytes
- differentiation
- activation
- dendritic cells
- allogeneic donors
- Prior art date
Links
- 230000004913 activation Effects 0.000 title 1
- 230000000735 allogeneic effect Effects 0.000 title 1
- 210000004443 dendritic cell Anatomy 0.000 title 1
- 210000001616 monocyte Anatomy 0.000 title 1
- 230000000770 proinflammatory effect Effects 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/40—Nucleotides, nucleosides or bases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2304—Interleukin-4 (IL-4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/24—Interferons [IFN]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
- C12N2506/115—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells from monocytes, from macrophages
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12197687 | 2012-12-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2913394T3 true PL2913394T3 (pl) | 2016-12-30 |
Family
ID=47427250
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL13814106T PL2788474T3 (pl) | 2012-12-18 | 2013-12-18 | Wspólne różnicowanie monocytów od dawców allogenicznych |
PL15161369.2T PL2913394T3 (pl) | 2012-12-18 | 2013-12-18 | Wspólne różnicowanie i aktywowanie monocytów od dawców allogenicznych dla dostarczenia prozapalnych komórek dendrytycznych |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL13814106T PL2788474T3 (pl) | 2012-12-18 | 2013-12-18 | Wspólne różnicowanie monocytów od dawców allogenicznych |
Country Status (16)
Country | Link |
---|---|
US (2) | US9714413B2 (pl) |
EP (2) | EP2913394B1 (pl) |
JP (1) | JP6529439B2 (pl) |
KR (1) | KR102148051B1 (pl) |
CN (2) | CN105452449B (pl) |
AU (1) | AU2013360793B2 (pl) |
BR (1) | BR112015014270B1 (pl) |
CA (1) | CA2895280C (pl) |
DK (2) | DK2913394T3 (pl) |
ES (2) | ES2591230T3 (pl) |
HU (2) | HUE028895T2 (pl) |
MX (1) | MX357491B (pl) |
PL (2) | PL2788474T3 (pl) |
RU (1) | RU2668816C2 (pl) |
SI (2) | SI2913394T1 (pl) |
WO (1) | WO2014096033A1 (pl) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI3460052T1 (sl) | 2017-09-20 | 2020-03-31 | Immunicum Ab | Izboljšane alogene dendritične celice za uporabo pri zdravljenju raka |
US20200338173A1 (en) * | 2018-01-18 | 2020-10-29 | University Of South Florida | Dead antigen stimulated immature heterogenous dendritic cells as therapeutics for diseases |
CN108660125A (zh) * | 2018-05-14 | 2018-10-16 | 武汉博百欧生物科技有限公司 | 一种从人体输血废弃物中提取中性粒细胞嗜天青颗粒的方法 |
WO2020154424A1 (en) * | 2019-01-22 | 2020-07-30 | The Brigham And Women's Hospital, Inc. | Antigen-presenting neutrophil-derived dendritic cells and methods of use thereof |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1259592A1 (en) * | 2000-01-11 | 2002-11-27 | Maxygen, Inc. | Monocyte-derived dendritic cell subsets |
AU2002326463A1 (en) | 2001-07-25 | 2003-02-17 | Northwest Biotherapeutics, Inc. | Methods and apparatus for enrichment and culture of monocytic dendritic cell precursors |
AU2003241252A1 (en) | 2002-06-06 | 2003-12-22 | Immunicum Ab | New method and composition for producing a cellular allogeneic vaccine |
KR100585456B1 (ko) * | 2003-09-30 | 2006-06-07 | 국립암센터 | 동종 종양-관련 항원이 탑재된 수지상세포, 이의 제조방법및 이를 유효성분으로 하는 암 치료용 백신 조성물 |
CA2504451A1 (en) * | 2004-08-10 | 2006-02-10 | Geron Corporation | Dendritic cell vaccines for treating cancer made from embryonic stem cells |
EP3805367A1 (en) * | 2005-12-08 | 2021-04-14 | NorthWest Biotherapeutics, Inc. | Compositions and methods for inducing the activation of immature monocytic dendritic cells |
EP1806395A1 (en) * | 2006-01-06 | 2007-07-11 | Stichting Sanquin Bloedvoorziening | Maturation of dendritic cells |
EP1840206A1 (en) * | 2006-03-28 | 2007-10-03 | Gsf-Forschungszentrum Für Umwelt Und Gesundheit, Gmbh | Compositions for the preparation of mature dendritic cells |
CN102597222B (zh) * | 2009-10-27 | 2015-07-15 | 因缪尼卡姆股份公司 | 用于增殖抗原特异性t细胞的方法 |
EP2534242B1 (en) * | 2010-02-10 | 2016-04-20 | Immunicum AB | Improved composition for inhibiting tumor cell proliferation |
US9492529B2 (en) * | 2011-04-13 | 2016-11-15 | Immunicum Ab | Method for priming of T cells |
CN103502439B (zh) * | 2011-04-13 | 2016-10-12 | 因缪尼卡姆股份公司 | 用于抗原特异性t细胞增殖的方法 |
-
2013
- 2013-12-18 CN CN201380066722.0A patent/CN105452449B/zh active Active
- 2013-12-18 PL PL13814106T patent/PL2788474T3/pl unknown
- 2013-12-18 WO PCT/EP2013/077139 patent/WO2014096033A1/en active Application Filing
- 2013-12-18 BR BR112015014270-2A patent/BR112015014270B1/pt not_active IP Right Cessation
- 2013-12-18 HU HUE15161369A patent/HUE028895T2/en unknown
- 2013-12-18 JP JP2015547082A patent/JP6529439B2/ja active Active
- 2013-12-18 RU RU2015119164A patent/RU2668816C2/ru active
- 2013-12-18 SI SI201330281A patent/SI2913394T1/sl unknown
- 2013-12-18 DK DK15161369.2T patent/DK2913394T3/en active
- 2013-12-18 MX MX2015007800A patent/MX357491B/es active IP Right Grant
- 2013-12-18 PL PL15161369.2T patent/PL2913394T3/pl unknown
- 2013-12-18 US US14/653,184 patent/US9714413B2/en active Active
- 2013-12-18 CN CN201910284719.5A patent/CN110042081B/zh active Active
- 2013-12-18 EP EP15161369.2A patent/EP2913394B1/en active Active
- 2013-12-18 SI SI201330066T patent/SI2788474T1/sl unknown
- 2013-12-18 CA CA2895280A patent/CA2895280C/en active Active
- 2013-12-18 EP EP13814106.4A patent/EP2788474B1/en active Active
- 2013-12-18 ES ES15161369.2T patent/ES2591230T3/es active Active
- 2013-12-18 KR KR1020157015766A patent/KR102148051B1/ko active IP Right Grant
- 2013-12-18 DK DK13814106.4T patent/DK2788474T3/en active
- 2013-12-18 AU AU2013360793A patent/AU2013360793B2/en active Active
- 2013-12-18 ES ES13814106.4T patent/ES2548229T3/es active Active
- 2013-12-18 HU HUE13814106A patent/HUE027619T2/en unknown
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2017
- 2017-06-15 US US15/623,530 patent/US10626371B2/en active Active
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