PL2913394T3 - Wspólne różnicowanie i aktywowanie monocytów od dawców allogenicznych dla dostarczenia prozapalnych komórek dendrytycznych - Google Patents

Wspólne różnicowanie i aktywowanie monocytów od dawców allogenicznych dla dostarczenia prozapalnych komórek dendrytycznych

Info

Publication number
PL2913394T3
PL2913394T3 PL15161369.2T PL15161369T PL2913394T3 PL 2913394 T3 PL2913394 T3 PL 2913394T3 PL 15161369 T PL15161369 T PL 15161369T PL 2913394 T3 PL2913394 T3 PL 2913394T3
Authority
PL
Poland
Prior art keywords
monocytes
differentiation
activation
dendritic cells
allogeneic donors
Prior art date
Application number
PL15161369.2T
Other languages
English (en)
Inventor
Alex Karlsson-Parra
Bengt Andersson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL2913394T3 publication Critical patent/PL2913394T3/pl

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/15Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0639Dendritic cells, e.g. Langherhans cells in the epidermis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/40Nucleotides, nucleosides or bases
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/22Colony stimulating factors (G-CSF, GM-CSF)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/23Interleukins [IL]
    • C12N2501/2304Interleukin-4 (IL-4)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/24Interferons [IFN]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/11Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
    • C12N2506/115Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells from monocytes, from macrophages

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL15161369.2T 2012-12-18 2013-12-18 Wspólne różnicowanie i aktywowanie monocytów od dawców allogenicznych dla dostarczenia prozapalnych komórek dendrytycznych PL2913394T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12197687 2012-12-18

Publications (1)

Publication Number Publication Date
PL2913394T3 true PL2913394T3 (pl) 2016-12-30

Family

ID=47427250

Family Applications (2)

Application Number Title Priority Date Filing Date
PL13814106T PL2788474T3 (pl) 2012-12-18 2013-12-18 Wspólne różnicowanie monocytów od dawców allogenicznych
PL15161369.2T PL2913394T3 (pl) 2012-12-18 2013-12-18 Wspólne różnicowanie i aktywowanie monocytów od dawców allogenicznych dla dostarczenia prozapalnych komórek dendrytycznych

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL13814106T PL2788474T3 (pl) 2012-12-18 2013-12-18 Wspólne różnicowanie monocytów od dawców allogenicznych

Country Status (16)

Country Link
US (2) US9714413B2 (pl)
EP (2) EP2913394B1 (pl)
JP (1) JP6529439B2 (pl)
KR (1) KR102148051B1 (pl)
CN (2) CN105452449B (pl)
AU (1) AU2013360793B2 (pl)
BR (1) BR112015014270B1 (pl)
CA (1) CA2895280C (pl)
DK (2) DK2913394T3 (pl)
ES (2) ES2591230T3 (pl)
HU (2) HUE028895T2 (pl)
MX (1) MX357491B (pl)
PL (2) PL2788474T3 (pl)
RU (1) RU2668816C2 (pl)
SI (2) SI2913394T1 (pl)
WO (1) WO2014096033A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3460052T1 (sl) 2017-09-20 2020-03-31 Immunicum Ab Izboljšane alogene dendritične celice za uporabo pri zdravljenju raka
US20200338173A1 (en) * 2018-01-18 2020-10-29 University Of South Florida Dead antigen stimulated immature heterogenous dendritic cells as therapeutics for diseases
CN108660125A (zh) * 2018-05-14 2018-10-16 武汉博百欧生物科技有限公司 一种从人体输血废弃物中提取中性粒细胞嗜天青颗粒的方法
WO2020154424A1 (en) * 2019-01-22 2020-07-30 The Brigham And Women's Hospital, Inc. Antigen-presenting neutrophil-derived dendritic cells and methods of use thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1259592A1 (en) * 2000-01-11 2002-11-27 Maxygen, Inc. Monocyte-derived dendritic cell subsets
AU2002326463A1 (en) 2001-07-25 2003-02-17 Northwest Biotherapeutics, Inc. Methods and apparatus for enrichment and culture of monocytic dendritic cell precursors
AU2003241252A1 (en) 2002-06-06 2003-12-22 Immunicum Ab New method and composition for producing a cellular allogeneic vaccine
KR100585456B1 (ko) * 2003-09-30 2006-06-07 국립암센터 동종 종양-관련 항원이 탑재된 수지상세포, 이의 제조방법및 이를 유효성분으로 하는 암 치료용 백신 조성물
CA2504451A1 (en) * 2004-08-10 2006-02-10 Geron Corporation Dendritic cell vaccines for treating cancer made from embryonic stem cells
EP3805367A1 (en) * 2005-12-08 2021-04-14 NorthWest Biotherapeutics, Inc. Compositions and methods for inducing the activation of immature monocytic dendritic cells
EP1806395A1 (en) * 2006-01-06 2007-07-11 Stichting Sanquin Bloedvoorziening Maturation of dendritic cells
EP1840206A1 (en) * 2006-03-28 2007-10-03 Gsf-Forschungszentrum Für Umwelt Und Gesundheit, Gmbh Compositions for the preparation of mature dendritic cells
CN102597222B (zh) * 2009-10-27 2015-07-15 因缪尼卡姆股份公司 用于增殖抗原特异性t细胞的方法
EP2534242B1 (en) * 2010-02-10 2016-04-20 Immunicum AB Improved composition for inhibiting tumor cell proliferation
US9492529B2 (en) * 2011-04-13 2016-11-15 Immunicum Ab Method for priming of T cells
CN103502439B (zh) * 2011-04-13 2016-10-12 因缪尼卡姆股份公司 用于抗原特异性t细胞增殖的方法

Also Published As

Publication number Publication date
CN105452449B (zh) 2019-05-07
DK2788474T3 (en) 2015-09-28
AU2013360793A1 (en) 2015-06-11
HUE027619T2 (en) 2016-10-28
CN105452449A (zh) 2016-03-30
EP2913394A1 (en) 2015-09-02
KR20150122624A (ko) 2015-11-02
EP2788474A1 (en) 2014-10-15
US10626371B2 (en) 2020-04-21
PL2788474T3 (pl) 2015-12-31
DK2913394T3 (en) 2016-09-19
EP2788474B1 (en) 2015-06-24
US9714413B2 (en) 2017-07-25
KR102148051B1 (ko) 2020-08-25
JP2016501529A (ja) 2016-01-21
CN110042081B (zh) 2023-09-01
JP6529439B2 (ja) 2019-06-12
ES2591230T3 (es) 2016-11-25
US20150329823A1 (en) 2015-11-19
RU2668816C2 (ru) 2018-10-02
MX2015007800A (es) 2016-01-12
AU2013360793B2 (en) 2019-01-31
CN110042081A (zh) 2019-07-23
WO2014096033A1 (en) 2014-06-26
RU2015119164A (ru) 2017-01-26
CA2895280C (en) 2021-04-06
BR112015014270A2 (pt) 2015-11-03
US20170321189A1 (en) 2017-11-09
BR112015014270B1 (pt) 2018-12-04
SI2788474T1 (sl) 2016-01-29
ES2548229T3 (es) 2015-10-15
HUE028895T2 (en) 2017-02-28
SI2913394T1 (sl) 2017-01-31
EP2913394B1 (en) 2016-06-22
CA2895280A1 (en) 2014-06-26
MX357491B (es) 2018-07-11

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