PL2882442T3 - Sposoby leczenia nowotworów z wykorzystaniem 3-(4-((4-(morfolinometylo)benzylo)oksy)-1-oksoizoindolin-2-ylo)piperydyno-2,6-dionu - Google Patents

Sposoby leczenia nowotworów z wykorzystaniem 3-(4-((4-(morfolinometylo)benzylo)oksy)-1-oksoizoindolin-2-ylo)piperydyno-2,6-dionu

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Publication number
PL2882442T3
PL2882442T3 PL13751007T PL13751007T PL2882442T3 PL 2882442 T3 PL2882442 T3 PL 2882442T3 PL 13751007 T PL13751007 T PL 13751007T PL 13751007 T PL13751007 T PL 13751007T PL 2882442 T3 PL2882442 T3 PL 2882442T3
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PL
Poland
Prior art keywords
oxoisoindolin
morpholinomethyl
dione
piperidine
oxy
Prior art date
Application number
PL13751007T
Other languages
English (en)
Polish (pl)
Inventor
Peter H. Schafer
Anita GANDHI
Original Assignee
Celgene Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corporation filed Critical Celgene Corporation
Publication of PL2882442T3 publication Critical patent/PL2882442T3/pl

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL13751007T 2012-08-09 2013-08-08 Sposoby leczenia nowotworów z wykorzystaniem 3-(4-((4-(morfolinometylo)benzylo)oksy)-1-oksoizoindolin-2-ylo)piperydyno-2,6-dionu PL2882442T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261681447P 2012-08-09 2012-08-09
US201261722727P 2012-11-05 2012-11-05
EP13751007.9A EP2882442B1 (en) 2012-08-09 2013-08-08 Methods of treating cancer using 3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
PCT/US2013/054055 WO2014025960A1 (en) 2012-08-09 2013-08-08 Methods of treating cancer using 3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

Publications (1)

Publication Number Publication Date
PL2882442T3 true PL2882442T3 (pl) 2021-12-13

Family

ID=49004013

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13751007T PL2882442T3 (pl) 2012-08-09 2013-08-08 Sposoby leczenia nowotworów z wykorzystaniem 3-(4-((4-(morfolinometylo)benzylo)oksy)-1-oksoizoindolin-2-ylo)piperydyno-2,6-dionu

Country Status (31)

Country Link
US (3) US20140045843A1 (enExample)
EP (2) EP2882442B1 (enExample)
JP (2) JP6347782B2 (enExample)
KR (3) KR102146848B1 (enExample)
CN (4) CN108245518B (enExample)
AU (1) AU2013299627C1 (enExample)
BR (1) BR112015002285B1 (enExample)
CA (1) CA2881116C (enExample)
CY (1) CY1124622T1 (enExample)
DK (1) DK2882442T3 (enExample)
EA (1) EA029485B1 (enExample)
ES (1) ES2881220T3 (enExample)
HR (1) HRP20211243T1 (enExample)
HU (1) HUE056127T2 (enExample)
IL (3) IL288506B2 (enExample)
IN (1) IN2015DN00886A (enExample)
LT (1) LT2882442T (enExample)
MX (1) MX367869B (enExample)
NI (1) NI201500012A (enExample)
NZ (1) NZ628078A (enExample)
PH (1) PH12015500212A1 (enExample)
PL (1) PL2882442T3 (enExample)
PT (1) PT2882442T (enExample)
RS (1) RS62201B1 (enExample)
SG (3) SG11201500998QA (enExample)
SI (1) SI2882442T1 (enExample)
SM (1) SMT202100457T1 (enExample)
TW (2) TWI723266B (enExample)
UA (1) UA116544C2 (enExample)
WO (1) WO2014025960A1 (enExample)
ZA (1) ZA201500564B (enExample)

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IL237013A0 (en) 2015-03-31
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PH12015500212A1 (en) 2015-03-30
SMT202100457T1 (it) 2021-09-14
HRP20211243T1 (hr) 2021-11-12
BR112015002285B1 (pt) 2022-05-10
CN104837491A (zh) 2015-08-12
TW201828944A (zh) 2018-08-16
KR20200098730A (ko) 2020-08-20
IL276319A (en) 2020-09-30
CN108245518B (zh) 2021-08-31
ES2881220T3 (es) 2021-11-29
EP2882442B1 (en) 2021-06-09
PT2882442T (pt) 2021-08-17
TWI653977B (zh) 2019-03-21
JP6347782B2 (ja) 2018-06-27
SI2882442T1 (sl) 2021-11-30
SG10202108516PA (en) 2021-09-29
CN108245518A (zh) 2018-07-06
CN114344307A (zh) 2022-04-15
IL288506B2 (en) 2023-09-01
TWI723266B (zh) 2021-04-01
EA029485B1 (ru) 2018-04-30
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IL288506B1 (en) 2023-05-01
US20160256468A1 (en) 2016-09-08
JP2018100276A (ja) 2018-06-28
SG10201701057SA (en) 2017-03-30
IL237013B (en) 2020-08-31
AU2013299627A1 (en) 2015-02-05
KR20210073617A (ko) 2021-06-18
ZA201500564B (en) 2016-06-29
HK1211489A1 (en) 2016-05-27
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WO2014025960A1 (en) 2014-02-13
US20140045843A1 (en) 2014-02-13
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AU2013299627B2 (en) 2018-02-15
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SG11201500998QA (en) 2015-04-29
HUE056127T2 (hu) 2022-01-28
EP3949968A1 (en) 2022-02-09
KR20150039850A (ko) 2015-04-13
US20190388429A1 (en) 2019-12-26
KR102146848B1 (ko) 2020-08-21
CY1124622T1 (el) 2022-07-22
IL288506A (en) 2022-01-01
CA2881116A1 (en) 2014-02-13
JP2015524478A (ja) 2015-08-24
UA116544C2 (uk) 2018-04-10
BR112015002285A2 (pt) 2017-07-04
LT2882442T (lt) 2021-09-27
IN2015DN00886A (enExample) 2015-06-12
MX367869B (es) 2019-09-10
KR102266510B1 (ko) 2021-06-16
NI201500012A (es) 2019-05-10
CN114366746A (zh) 2022-04-19
EA201590345A1 (ru) 2015-06-30
DK2882442T3 (da) 2021-08-16
TW201434466A (zh) 2014-09-16
KR102414005B1 (ko) 2022-06-27
MX2015001775A (es) 2015-05-12

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