PL2723771T3 - Białka wiążące albuminy surowicy - Google Patents
Białka wiążące albuminy surowicyInfo
- Publication number
- PL2723771T3 PL2723771T3 PL12727658T PL12727658T PL2723771T3 PL 2723771 T3 PL2723771 T3 PL 2723771T3 PL 12727658 T PL12727658 T PL 12727658T PL 12727658 T PL12727658 T PL 12727658T PL 2723771 T3 PL2723771 T3 PL 2723771T3
- Authority
- PL
- Poland
- Prior art keywords
- serum albumin
- binding proteins
- albumin binding
- proteins
- serum
- Prior art date
Links
- 102000014914 Carrier Proteins Human genes 0.000 title 1
- 102000007562 Serum Albumin Human genes 0.000 title 1
- 108010071390 Serum Albumin Proteins 0.000 title 1
- 108091008324 binding proteins Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/22—Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161500464P | 2011-06-23 | 2011-06-23 | |
| PCT/EP2012/061304 WO2012175400A1 (en) | 2011-06-23 | 2012-06-14 | Serum albumin binding proteins |
| EP12727658.2A EP2723771B1 (en) | 2011-06-23 | 2012-06-14 | Serum albumin binding proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2723771T3 true PL2723771T3 (pl) | 2020-04-30 |
Family
ID=46298413
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12727658T PL2723771T3 (pl) | 2011-06-23 | 2012-06-14 | Białka wiążące albuminy surowicy |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US9573992B2 (cg-RX-API-DMAC7.html) |
| EP (3) | EP2723771B1 (cg-RX-API-DMAC7.html) |
| JP (3) | JP6324887B2 (cg-RX-API-DMAC7.html) |
| CN (2) | CN106046168A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2012271974B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2839779C (cg-RX-API-DMAC7.html) |
| CY (1) | CY1122691T1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK2723771T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2759936T3 (cg-RX-API-DMAC7.html) |
| HR (2) | HRP20192160T1 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE047238T2 (cg-RX-API-DMAC7.html) |
| IN (1) | IN2014CN00414A (cg-RX-API-DMAC7.html) |
| LT (1) | LT2723771T (cg-RX-API-DMAC7.html) |
| PL (1) | PL2723771T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2723771T (cg-RX-API-DMAC7.html) |
| SI (1) | SI2723771T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012175400A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (91)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11644471B2 (en) | 2010-09-30 | 2023-05-09 | Ablynx N.V. | Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains |
| WO2012042026A1 (en) | 2010-09-30 | 2012-04-05 | Ablynx Nv | Biological materials related to c-met |
| SG194982A1 (en) * | 2011-06-23 | 2013-12-30 | Ablynx Nv | Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains |
| CN106046168A (zh) * | 2011-06-23 | 2016-10-26 | 埃博灵克斯股份有限公司 | 结合血清白蛋白的蛋白 |
| JP6219287B2 (ja) * | 2011-09-30 | 2017-10-25 | アブリンクス エン．ヴェー． | ｃ−Ｍｅｔに関連する生物学的物質 |
| US9346884B2 (en) | 2011-09-30 | 2016-05-24 | Ablynx N.V. | Biological materials related to c-Met |
| WO2014087010A1 (en) | 2012-12-07 | 2014-06-12 | Ablynx N.V. | IMPROVED POLYPEPTIDES DIRECTED AGAINST IgE |
| RS63085B1 (sr) | 2014-05-16 | 2022-04-29 | Ablynx Nv | Varijabilni domeni imunoglobulina |
| IL318433A (en) | 2014-05-16 | 2025-03-01 | Ablynx Nv | Improved immunoglobulin variable complexes |
| EP3143403B1 (en) | 2014-05-16 | 2021-10-27 | Ablynx N.V. | Methods for detecting and/or measuring anti-drug antibodies, in particular treatment-emergent anti-drug antibodies |
| NL2013661B1 (en) | 2014-10-21 | 2016-10-05 | Ablynx Nv | KV1.3 Binding immunoglobulins. |
| EP3233910B1 (en) | 2014-12-19 | 2019-12-11 | Ablynx N.V. | Cysteine linked nanobody dimers |
| CN107531781B (zh) | 2015-01-29 | 2021-12-07 | 抗菌技术,生物技术研究与发展股份有限公司 | 用于阿尔茨海默病和相关紊乱的抗体分子和肽递送系统 |
| SG10202002131PA (en) | 2015-05-21 | 2020-05-28 | Harpoon Therapeutics Inc | Trispecific binding proteins and methods of use |
| NO2768984T3 (cg-RX-API-DMAC7.html) | 2015-11-12 | 2018-06-09 | ||
| PL3374392T3 (pl) * | 2015-11-13 | 2022-03-28 | Ablynx Nv | Ulepszone domeny zmienne immunoglobuliny wiążące albuminę surowicy |
| SG10201911035QA (en) | 2015-11-18 | 2020-01-30 | Merck Sharp & Dohme | Pd1 and/or lag3 binders |
| WO2017087587A1 (en) | 2015-11-18 | 2017-05-26 | Merck Sharp & Dohme Corp. | PD1/CTLA4 Binders |
| US11332519B2 (en) * | 2015-11-18 | 2022-05-17 | Ablynx N.V. | Serum albumin binders |
| GEP20207174B (en) | 2015-11-18 | 2020-11-10 | Merck Sharp & Dohme | Ctla4 binders |
| SG11201803976VA (en) * | 2015-11-27 | 2018-06-28 | Ablynx Nv | Polypeptides inhibiting cd40l |
| US11623958B2 (en) | 2016-05-20 | 2023-04-11 | Harpoon Therapeutics, Inc. | Single chain variable fragment CD3 binding proteins |
| CN109641047A (zh) * | 2016-05-20 | 2019-04-16 | 哈普恩治疗公司 | 单结构域血清白蛋白结合蛋白质 |
| JP7150618B2 (ja) | 2016-06-23 | 2022-10-11 | アブリンクス エン．ヴェー． | 免疫グロブリン単一可変ドメインについての改善された薬物動態アッセイ |
| IL266506B2 (en) | 2016-11-16 | 2025-05-01 | Ablynx Nv | T cell recruiting polypeptides capable of binding cd123 and tcr alpha/beta |
| WO2018104444A1 (en) * | 2016-12-07 | 2018-06-14 | Ablynx Nv | Improved serum albumin binding immunoglobulin single variable domains |
| CN107674122A (zh) * | 2016-12-28 | 2018-02-09 | 天津天锐生物科技有限公司 | 一种识别人血清白蛋白的单域抗体 |
| DK3571225T3 (da) | 2017-01-17 | 2024-11-04 | Ablynx Nv | Forbedrede serumalbuminbindere |
| WO2018134234A1 (en) * | 2017-01-17 | 2018-07-26 | Ablynx Nv | Improved serum albumin binders |
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| EP2723771B1 (en) | 2019-09-11 |
| JP2018127478A (ja) | 2018-08-16 |
| EP2723771A1 (en) | 2014-04-30 |
| CA2839779A1 (en) | 2012-12-27 |
| HUE047238T2 (hu) | 2020-04-28 |
| AU2012271974B2 (en) | 2017-01-12 |
| JP6843090B2 (ja) | 2021-03-17 |
| CN103619878A (zh) | 2014-03-05 |
| HRP20192160T1 (hr) | 2020-02-21 |
| US9573992B2 (en) | 2017-02-21 |
| JP6324887B2 (ja) | 2018-05-16 |
| AU2012271974A1 (en) | 2013-12-12 |
| US20140228546A1 (en) | 2014-08-14 |
| ES2759936T3 (es) | 2020-05-12 |
| CN106046168A (zh) | 2016-10-26 |
| SI2723771T1 (sl) | 2019-12-31 |
| WO2012175400A1 (en) | 2012-12-27 |
| EP4218933A1 (en) | 2023-08-02 |
| IN2014CN00414A (cg-RX-API-DMAC7.html) | 2015-04-03 |
| LT2723771T (lt) | 2019-12-10 |
| CA2839779C (en) | 2020-10-06 |
| JP2014520129A (ja) | 2014-08-21 |
| HRP20170535T4 (hr) | 2022-08-19 |
| CY1122691T1 (el) | 2021-03-12 |
| DK2723771T3 (da) | 2019-12-02 |
| EP3466972A1 (en) | 2019-04-10 |
| JP2021088585A (ja) | 2021-06-10 |
| JP7304375B2 (ja) | 2023-07-06 |
| HRP20170535T1 (hr) | 2017-06-16 |
| CN103619878B (zh) | 2016-10-26 |
| US20170210789A1 (en) | 2017-07-27 |
| PT2723771T (pt) | 2019-12-11 |
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