PL2535403T3 - Bardzo małe komórki macierzyste typu embrionalnego (VSEL) oraz sposoby ich izolowania i zastosowania - Google Patents

Bardzo małe komórki macierzyste typu embrionalnego (VSEL) oraz sposoby ich izolowania i zastosowania

Info

Publication number
PL2535403T3
PL2535403T3 PL12166007T PL12166007T PL2535403T3 PL 2535403 T3 PL2535403 T3 PL 2535403T3 PL 12166007 T PL12166007 T PL 12166007T PL 12166007 T PL12166007 T PL 12166007T PL 2535403 T3 PL2535403 T3 PL 2535403T3
Authority
PL
Poland
Prior art keywords
vsel
isolating
methods
same
stem cells
Prior art date
Application number
PL12166007T
Other languages
English (en)
Inventor
Mariusz Ratajczak
Magdalena Kucia
Janina Ratajczak
Original Assignee
Univ Louisville Res Found Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Louisville Res Found Inc filed Critical Univ Louisville Res Found Inc
Publication of PL2535403T3 publication Critical patent/PL2535403T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL12166007T 2005-12-08 2006-11-02 Bardzo małe komórki macierzyste typu embrionalnego (VSEL) oraz sposoby ich izolowania i zastosowania PL2535403T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US74868505P 2005-12-08 2005-12-08
EP06827358A EP1974018A4 (en) 2005-12-08 2006-11-02 VSEL (VERY SMALL EMBRYONIC LIKE) STEM CELLS AND METHOD OF ISOLATING AND USE THEREOF
PCT/US2006/042780 WO2007067280A2 (en) 2005-12-08 2006-11-02 Very small embryonic-like (vsel) stem cells and methods of isolating and using the same
EP12166007.0A EP2535403B1 (en) 2005-12-08 2006-11-02 Very small embryonic-like (VSEL) stem cells and methods of isolating and using the same

Publications (1)

Publication Number Publication Date
PL2535403T3 true PL2535403T3 (pl) 2019-10-31

Family

ID=38123356

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12166007T PL2535403T3 (pl) 2005-12-08 2006-11-02 Bardzo małe komórki macierzyste typu embrionalnego (VSEL) oraz sposoby ich izolowania i zastosowania

Country Status (6)

Country Link
US (1) US20090220466A1 (pl)
EP (2) EP2535403B1 (pl)
CN (2) CN103952373A (pl)
HK (1) HK1200866A1 (pl)
PL (1) PL2535403T3 (pl)
WO (1) WO2007067280A2 (pl)

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WO2009059032A2 (en) 2007-10-30 2009-05-07 University Of Louisville Research Foundation, Inc. Uses and isolation of very small embryonic-like (vsel) stem cells
US9155762B2 (en) 2005-12-08 2015-10-13 University Of Louisville Research Foundation, Inc. Uses and isolation of stem cells from bone marrow
WO2008075370A2 (en) * 2006-12-21 2008-06-26 Biokine Therapeutics Ltd. T-140 peptide analogs having cxcr4 super-agonist activity for cancer therapy
WO2009092092A1 (en) * 2008-01-18 2009-07-23 Regents Of The University Of Minnesota Stem cell aggregates and methods for making and using
GB0805670D0 (en) * 2008-03-28 2008-04-30 Smith & Nephew Increasing the plasticity of stem cells
AU2009244308A1 (en) * 2008-05-06 2009-11-12 Joslin Diabetes Center, Inc. Methods and compositions for inducing brown adipogenesis
CA2723765A1 (en) * 2008-05-08 2009-11-12 Coretherapix Slu Multipotent adult stem cell population
WO2010039241A1 (en) * 2008-09-30 2010-04-08 University Of Louisville Research Foundation, Inc. Methods for isolating very small embryonic-like (vsel) stem cells
US20120114614A1 (en) * 2008-11-14 2012-05-10 Janina Ratajczak Methods and compositions for long term hematopoietic repopulation
US9427456B2 (en) 2009-06-14 2016-08-30 Biokine Therapeutics Ltd. Peptide therapy for increasing platelet levels
CN101962628B (zh) * 2009-07-24 2013-03-20 北京大学 肝脏内胚层细胞及其制备和纯化方法
WO2011069117A1 (en) * 2009-12-04 2011-06-09 Neostem, Inc. Method of isolation of stem cell populations from peripheral blood using sized-based separation (elutriation)
CN102373176B (zh) * 2010-08-23 2014-02-12 杨跃进 一种极小类胚胎样干细胞的制备方法
SG10201914007YA (en) 2010-08-24 2020-03-30 Univ Minnesota Non-static suspension culture of cell aggregates
WO2012048292A2 (en) * 2010-10-07 2012-04-12 University Of Louisville Research Foundation Inc. Igf-1 dependent modulation of vsels
US9078878B2 (en) 2010-12-01 2015-07-14 Alderbio Holdings Llc Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75
NZ611076A (en) 2010-12-01 2015-09-25 Alderbio Holdings Llc Anti-ngf compositions and use thereof
US9539324B2 (en) 2010-12-01 2017-01-10 Alderbio Holdings, Llc Methods of preventing inflammation and treating pain using anti-NGF compositions
US9067988B2 (en) 2010-12-01 2015-06-30 Alderbio Holdings Llc Methods of preventing or treating pain using anti-NGF antibodies
US9884909B2 (en) 2010-12-01 2018-02-06 Alderbio Holdings Llc Anti-NGF compositions and use thereof
US11214610B2 (en) 2010-12-01 2022-01-04 H. Lundbeck A/S High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
US20140154219A1 (en) * 2011-04-01 2014-06-05 University Of Louisville Research Foundation, Inc. Methods and compositions for large-scale isolation of very small embryonic-like (vsel) stem cells
AU2012239874A1 (en) * 2011-04-08 2013-10-31 Neostem, Inc. Autologous human adult pluripotent Very Small Embryonic-Like (hVSEL) Stem Cell regeneration of bone and cartilage
CN102229910B (zh) * 2011-05-23 2013-09-11 杨跃进 一种分选人骨髓极小胚胎样干细胞的方法
US9422526B2 (en) 2011-06-14 2016-08-23 The University Of North Carolina At Chapel Hill Isolation, expansion and use of autologous pluripotent stem cells
CN102864123B (zh) * 2011-07-06 2015-04-22 北京大学第三医院 一种外周血间充质干细胞的获得方法及其应用
WO2013160895A1 (en) 2012-04-24 2013-10-31 Biokine Therapeutics Ltd. Peptides and use thereof in the treatment of large cell lung cancer
US20140302493A1 (en) * 2013-03-14 2014-10-09 Irvine Scientific Sales Company, Inc. Method and quality control molecular based mouse embryo assay for use with in vitro fertilization technology
US11229789B2 (en) 2013-05-30 2022-01-25 Neurostim Oab, Inc. Neuro activator with controller
JP2016523125A (ja) 2013-05-30 2016-08-08 グラハム エイチ． クリーシー 局所神経性刺激
CN105675378A (zh) * 2014-11-18 2016-06-15 上海张江转化医学研发中心有限公司 一种简单的分离单个循环肿瘤细胞的方法和装置
US11077301B2 (en) 2015-02-21 2021-08-03 NeurostimOAB, Inc. Topical nerve stimulator and sensor for bladder control
EP3744340A3 (en) 2015-07-16 2021-03-03 Biokine Therapeutics Ltd. Compositions and methods for treating cancer
US11312940B2 (en) 2015-08-31 2022-04-26 University Of Louisville Research Foundation, Inc. Progenitor cells and methods for preparing and using the same
US20180369287A1 (en) 2015-10-08 2018-12-27 Neurona Therapeutics Inc. Neural precursor cell populations and uses thereof
HK1254739A1 (zh) 2015-11-04 2019-07-26 The Board Of Regents Of The University Of Texas System 从年长细胞群中富集和扩增高潜能人间充质干细胞
CN105532642B (zh) * 2015-12-25 2018-04-10 华中农业大学 一种团头鲂成鱼肌间骨染色的方法及应用
US10993985B2 (en) 2016-02-23 2021-05-04 BioLmeRx Ltd. Methods of treating acute myeloid leukemia
WO2017152073A1 (en) 2016-03-04 2017-09-08 University Of Louisville Research Foundation, Inc. Methods and compositions for ex vivo expansion of very small embryonic-like stem cells (vsels)
CN106047804B (zh) * 2016-05-30 2019-11-12 浙江大学 一种脂肪干细胞的纯化方法及干细胞在成骨诱导及成软骨诱导上的应用
US10953225B2 (en) 2017-11-07 2021-03-23 Neurostim Oab, Inc. Non-invasive nerve activator with adaptive circuit
CN108588009A (zh) * 2018-05-10 2018-09-28 广州四叶草健康科技有限公司 一种分离并激活人外周血极小胚胎样干细胞的方法
WO2020264214A1 (en) 2019-06-26 2020-12-30 Neurostim Technologies Llc Non-invasive nerve activator with adaptive circuit
CN110412002B (zh) * 2019-08-08 2022-01-11 中山大学孙逸仙纪念医院 一种鉴别人源细胞和小鼠源细胞的方法
WO2021126921A1 (en) 2019-12-16 2021-06-24 Neurostim Solutions, Llc Non-invasive nerve activator with boosted charge delivery
CN119955716B (zh) * 2025-04-10 2025-07-25 深圳泰华赛尔生物科技有限公司 一种脂肪来源极小类胚胎样干细胞的培养基与培养方法、应用

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Also Published As

Publication number Publication date
CN101573441A (zh) 2009-11-04
WO2007067280A3 (en) 2009-04-30
EP1974018A2 (en) 2008-10-01
HK1200866A1 (en) 2015-08-14
WO2007067280A2 (en) 2007-06-14
EP2535403B1 (en) 2019-06-19
CN103952373A (zh) 2014-07-30
EP2535403A1 (en) 2012-12-19
EP1974018A4 (en) 2010-01-27
US20090220466A1 (en) 2009-09-03

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