PL2301943T3 - Krystalizacja epidaunorubicyny x HCI - Google Patents

Krystalizacja epidaunorubicyny x HCI

Info

Publication number
PL2301943T3
PL2301943T3 PL09011459T PL09011459T PL2301943T3 PL 2301943 T3 PL2301943 T3 PL 2301943T3 PL 09011459 T PL09011459 T PL 09011459T PL 09011459 T PL09011459 T PL 09011459T PL 2301943 T3 PL2301943 T3 PL 2301943T3
Authority
PL
Poland
Prior art keywords
epidaunorubicin
hci
crystallization
Prior art date
Application number
PL09011459T
Other languages
English (en)
Inventor
Tero Kunnari
Holger Bindernagel
Sascha Weiser
Andrew Lupton
Stefan Wallert
Original Assignee
Heraeus Precious Metals Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41483008&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2301943(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Heraeus Precious Metals Gmbh filed Critical Heraeus Precious Metals Gmbh
Publication of PL2301943T3 publication Critical patent/PL2301943T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
PL09011459T 2009-09-08 2009-09-08 Krystalizacja epidaunorubicyny x HCI PL2301943T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP09011459.6A EP2301943B1 (en) 2009-09-08 2009-09-08 Crystallization of epidaunorubicin x HCI

Publications (1)

Publication Number Publication Date
PL2301943T3 true PL2301943T3 (pl) 2014-06-30

Family

ID=41483008

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09011459T PL2301943T3 (pl) 2009-09-08 2009-09-08 Krystalizacja epidaunorubicyny x HCI

Country Status (16)

Country Link
US (3) US8686164B2 (pl)
EP (2) EP2301943B1 (pl)
JP (2) JP5858481B2 (pl)
KR (1) KR101480376B1 (pl)
CN (2) CN105713055A (pl)
AU (1) AU2010294532B2 (pl)
BR (1) BR112012005126A8 (pl)
CA (1) CA2772260C (pl)
HR (1) HRP20140263T1 (pl)
MX (1) MX2012002869A (pl)
PL (1) PL2301943T3 (pl)
RU (1) RU2564415C2 (pl)
SG (1) SG178461A1 (pl)
UA (1) UA111580C2 (pl)
WO (1) WO2011029576A1 (pl)
ZA (1) ZA201202405B (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2301943B1 (en) * 2009-09-08 2014-01-08 Heraeus Precious Metals GmbH & Co. KG Crystallization of epidaunorubicin x HCI
DE102011103751A1 (de) * 2011-05-31 2012-12-06 Heraeus Precious Metals Gmbh & Co. Kg Kristallisierung von Epirubicinhydrochlorid
KR101428340B1 (ko) * 2012-12-31 2014-08-07 현대자동차주식회사 이온성 용매를 이용한 락타이드 제조법
US10300070B2 (en) 2014-03-27 2019-05-28 The Brigham And Women's Hospital, Inc. Metabolically-activated drug conjugates to overcome resistance in cancer therapy
DE102014208194A1 (de) * 2014-04-30 2015-11-05 Heraeus Deutschland GmbH & Co. KG Aufreinigung von Epidaunorubicin
KR102155411B1 (ko) 2015-03-30 2020-09-11 메이지 세이카 파루마 가부시키가이샤 에피루비신 제조방법 및 그의 신규한 제조 중간체
CN109384822B (zh) * 2017-08-11 2021-08-03 鲁南制药集团股份有限公司 一种盐酸表柔比星晶型及其制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1506200A (en) 1975-04-30 1978-04-05 Farmaceutici Italia Glycosides
US4345068A (en) * 1979-11-22 1982-08-17 Farmitalia Carlo Erba S.P.A. Process for the preparation of 4'-epidaunorubicin, 3',4'-diepidaunorubicin, their doxorubicin analogs, and intermediates used in said process
IT1155446B (it) 1982-12-23 1987-01-28 Erba Farmitalia Procedimento per la purificazione di glucosidi antraciclinonici mediante adsobimento selettivo su resine
JPS6442498A (en) * 1987-08-07 1989-02-14 Biogal Gyogyszergyar Improvement for collecting daunorubicin hydrochloride from fermentation liquid
IT1275953B1 (it) 1995-03-22 1997-10-24 Sicor Spa Procedimento per la preparazione di antibiotici della classe delle antracicline
ES2151632T3 (es) 1996-12-16 2001-01-01 Pharmachemie Bv Un proceso para preparar epirubicina o sales de adicion de acidos de la misma a partir de daunorubicina.
DE69833220T2 (de) * 1997-11-28 2006-07-13 Dainippon Sumitomo Pharma Co., Ltd. Kristallines amrubicin-hydrochlorid
WO1999029708A1 (fr) * 1997-12-05 1999-06-17 Mercian Corporation Anthracycline cristalline antibiotique et son procede de production
WO2000023453A1 (fr) * 1998-10-16 2000-04-27 Mercian Corporation Cristallisation de chlorhydrate de doxorubicine
US7485707B2 (en) * 2003-07-02 2009-02-03 Solux Corporation Thermally stable crystalline epirubicin hydrochloride and method of making the same
US8802830B2 (en) * 2005-12-20 2014-08-12 Solux Corporation Synthesis of epirubicin from 13-dihydrodaunorubicine
WO2007077563A2 (en) * 2006-01-04 2007-07-12 Do-Coop Technologies Ltd. Solid-fluid composition
EP1990405B1 (en) 2007-05-08 2017-07-26 Provivo Oy Genetically modified strains producing anthracycline metabolites useful as cancer drugs
EP2262452A1 (en) * 2008-03-13 2010-12-22 Enbio Limited Surface modification of nitinol
EP2301943B1 (en) 2009-09-08 2014-01-08 Heraeus Precious Metals GmbH & Co. KG Crystallization of epidaunorubicin x HCI

Also Published As

Publication number Publication date
EP2636676A3 (en) 2014-01-01
MX2012002869A (es) 2012-09-07
ZA201202405B (en) 2012-12-27
KR101480376B1 (ko) 2015-01-09
JP2013503826A (ja) 2013-02-04
US8822658B2 (en) 2014-09-02
EP2636676A2 (en) 2013-09-11
CA2772260C (en) 2015-02-24
AU2010294532A1 (en) 2012-03-08
US20140148587A1 (en) 2014-05-29
KR20120068023A (ko) 2012-06-26
US8686164B2 (en) 2014-04-01
CN105713055A (zh) 2016-06-29
EP2301943A1 (en) 2011-03-30
WO2011029576A1 (en) 2011-03-17
US20120232291A1 (en) 2012-09-13
HRP20140263T1 (hr) 2014-04-25
JP2016094445A (ja) 2016-05-26
CN103347891B (zh) 2016-06-01
JP5858481B2 (ja) 2016-02-10
US9434756B2 (en) 2016-09-06
BR112012005126A2 (pt) 2017-10-03
EP2301943B1 (en) 2014-01-08
CA2772260A1 (en) 2011-03-17
CN103347891A (zh) 2013-10-09
US20140357848A1 (en) 2014-12-04
SG178461A1 (en) 2012-03-29
BR112012005126A8 (pt) 2018-02-14
RU2012113549A (ru) 2013-10-20
AU2010294532B2 (en) 2014-04-10
UA111580C2 (uk) 2016-05-25
RU2564415C2 (ru) 2015-09-27

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