ATE520702T1 - Thermisch stabiles kristallines epirubicin- hydrochlorid und herstellungsverfahren dafür - Google Patents

Thermisch stabiles kristallines epirubicin- hydrochlorid und herstellungsverfahren dafür

Info

Publication number
ATE520702T1
ATE520702T1 AT04777189T AT04777189T ATE520702T1 AT E520702 T1 ATE520702 T1 AT E520702T1 AT 04777189 T AT04777189 T AT 04777189T AT 04777189 T AT04777189 T AT 04777189T AT E520702 T1 ATE520702 T1 AT E520702T1
Authority
AT
Austria
Prior art keywords
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Prior art date
Application number
AT04777189T
Other languages
English (en)
Inventor
Alexander Zabudkin
Victor Matvienko
Alexey Matvyeyev
Aleksandr Itkin
Original Assignee
Solux Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34062027&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE520702(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Solux Corp filed Critical Solux Corp
Application granted granted Critical
Publication of ATE520702T1 publication Critical patent/ATE520702T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT04777189T 2003-07-02 2004-06-25 Thermisch stabiles kristallines epirubicin- hydrochlorid und herstellungsverfahren dafür ATE520702T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48413203P 2003-07-02 2003-07-02
PCT/US2004/020679 WO2005004805A2 (en) 2003-07-02 2004-06-25 Thermally stable crystalline epirubicin hydrochloride and method of making the same

Publications (1)

Publication Number Publication Date
ATE520702T1 true ATE520702T1 (de) 2011-09-15

Family

ID=34062027

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04777189T ATE520702T1 (de) 2003-07-02 2004-06-25 Thermisch stabiles kristallines epirubicin- hydrochlorid und herstellungsverfahren dafür

Country Status (7)

Country Link
US (1) US7485707B2 (de)
EP (1) EP1638509B1 (de)
CN (1) CN100412084C (de)
AT (1) ATE520702T1 (de)
DE (1) DE04777189T1 (de)
RU (1) RU2341530C2 (de)
WO (1) WO2005004805A2 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090099346A1 (en) * 2003-07-02 2009-04-16 Victor Matvienko Thermally stable crystalline epirubicin hydrochloride
CA2606390A1 (en) * 2005-05-11 2006-11-16 Sicor, Inc. Stable lyophilized anthracycline glycosides
US8802830B2 (en) * 2005-12-20 2014-08-12 Solux Corporation Synthesis of epirubicin from 13-dihydrodaunorubicine
PL2301943T3 (pl) * 2009-09-08 2014-06-30 Heraeus Precious Metals Gmbh Krystalizacja epidaunorubicyny x HCI
KR101125460B1 (ko) 2010-03-24 2012-03-28 동아제약주식회사 에피루비신 염산염의 신규한 결정형
ES2862331T3 (es) 2010-06-18 2021-10-07 Myriad Genetics Inc Métodos para predecir el estado de los genes BRCA1 y BRCA2 en una célula de cáncer
NZ606725A (en) 2010-08-24 2014-06-27 Dana Farber Cancer Inst Inc Methods for predicting anti-cancer response
CN102120750B (zh) * 2011-01-30 2013-04-03 山东新时代药业有限公司 一种盐酸表柔比星的纯化方法
DE102011103751A1 (de) * 2011-05-31 2012-12-06 Heraeus Precious Metals Gmbh & Co. Kg Kristallisierung von Epirubicinhydrochlorid
ES2768344T3 (es) 2011-06-17 2020-06-22 Myriad Genetics Inc Métodos y materiales para evaluar el desequilibrio alélico
DE102011111991A1 (de) * 2011-08-30 2013-02-28 Lead Discovery Center Gmbh Neue Cyclosporin-Derivate
DE102011113652A1 (de) * 2011-09-19 2013-03-21 Heraeus Precious Metals Gmbh & Co. Kg Kristallisierung von Idarubicinhydrochlorid
JP6325453B2 (ja) 2011-12-21 2018-05-16 ミリアド・ジェネティックス・インコーポレイテッド ヘテロ接合性の消失（ｌｏｓｓｏｆｈｅｔｅｒｏｚｙｇｏｓｉｔｙ）を評価するための方法および材料
CA2864481C (en) 2012-02-23 2020-07-14 The Children's Hospital Corporation Methods for predicting anti-cancer response
EP2859118B1 (de) 2012-06-07 2017-11-22 Institut Curie Verfahren zur detektion der deaktivierung des pfades der homologen rekombination (brca1/2) in menschlichen tumoren
US10308986B2 (en) 2013-03-14 2019-06-04 Children's Medical Center Corporation Cancer diagnosis, treatment selection and treatment
EP2778171A1 (de) * 2013-03-15 2014-09-17 Synbias Pharma Ltd. Kristallines Monohydrat von Epirubicinhydrochlorid
NZ712663A (en) 2013-04-05 2021-07-30 Myriad Genetics Inc Methods and materials for assessing homologous recombination deficiency
ES2909899T3 (es) 2013-12-09 2022-05-10 Inst Curie Métodos para detectar inactivación de la ruta de recombinación homóloga (BRCA1/2) en tumores humanos
EP3686288B1 (de) 2014-08-15 2023-03-08 Myriad Genetics, Inc. Verfahren und materialien zur beurteilung eines mangels an homologer rekombination
CN104861014B (zh) * 2015-06-03 2017-09-29 道中道（菏泽）制药有限公司 一种盐酸表阿霉素结晶的制备方法
EP4141127A1 (de) 2021-08-30 2023-03-01 Zentrum Familiärer Brust- und Eierstockkrebs Universitätsklinik Köln Verfahren zur bewertung des mangels an homologer rekombination in eierstockkrebszellen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1506200A (en) * 1975-04-30 1978-04-05 Farmaceutici Italia Glycosides
US4345068A (en) * 1979-11-22 1982-08-17 Farmitalia Carlo Erba S.P.A. Process for the preparation of 4'-epidaunorubicin, 3',4'-diepidaunorubicin, their doxorubicin analogs, and intermediates used in said process
IT1155446B (it) 1982-12-23 1987-01-28 Erba Farmitalia Procedimento per la purificazione di glucosidi antraciclinonici mediante adsobimento selettivo su resine
GB8426672D0 (en) * 1984-10-22 1984-11-28 Erba Farmitalia Pharmaceutical compositions
US5977082A (en) * 1985-08-02 1999-11-02 Pharmacia & Upjohn Company Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
IT1275953B1 (it) 1995-03-22 1997-10-24 Sicor Spa Procedimento per la preparazione di antibiotici della classe delle antracicline
EP0848009B1 (de) * 1996-12-16 2000-08-16 Pharmachemie B.V. Verfahren zur Herstellung von Epirubicin oder Zusatzsalzen davon, von Daunorubicin
DK1034181T3 (da) * 1997-11-28 2006-03-20 Dainippon Sumitomo Pharma Co Krystallinsk amrubicinhydrochlorid

Also Published As

Publication number Publication date
EP1638509B1 (de) 2015-12-30
EP1638509A4 (de) 2009-12-09
EP1638509A2 (de) 2006-03-29
CN100412084C (zh) 2008-08-20
DE04777189T1 (de) 2011-04-07
US20060063726A1 (en) 2006-03-23
WO2005004805A2 (en) 2005-01-20
US7485707B2 (en) 2009-02-03
WO2005004805A3 (en) 2006-06-22
RU2006101764A (ru) 2007-08-10
CN1871249A (zh) 2006-11-29
RU2341530C2 (ru) 2008-12-20

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