PL211695B1 - Sposób wytwarzania modafinilu - Google Patents
Sposób wytwarzania modafiniluInfo
- Publication number
- PL211695B1 PL211695B1 PL373792A PL37379203A PL211695B1 PL 211695 B1 PL211695 B1 PL 211695B1 PL 373792 A PL373792 A PL 373792A PL 37379203 A PL37379203 A PL 37379203A PL 211695 B1 PL211695 B1 PL 211695B1
- Authority
- PL
- Poland
- Prior art keywords
- benzhydrylthiol
- acid
- acetamide
- reacting
- modafinil
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38317302P | 2002-05-23 | 2002-05-23 | |
| US10/443,327 US6875893B2 (en) | 2002-05-23 | 2003-05-22 | Preparations of a sulfinyl acetamide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL373792A1 PL373792A1 (en) | 2005-09-19 |
| PL211695B1 true PL211695B1 (pl) | 2012-06-29 |
Family
ID=29586987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL373792A PL211695B1 (pl) | 2002-05-23 | 2003-05-23 | Sposób wytwarzania modafinilu |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US6875893B2 (enExample) |
| EP (1) | EP1506171B1 (enExample) |
| JP (1) | JP4351627B2 (enExample) |
| KR (1) | KR100984571B1 (enExample) |
| CN (1) | CN100379721C (enExample) |
| AR (1) | AR039857A1 (enExample) |
| AT (1) | ATE414058T1 (enExample) |
| BR (1) | BR0311242A (enExample) |
| CA (1) | CA2486533C (enExample) |
| CY (1) | CY1108747T1 (enExample) |
| DE (1) | DE60324671D1 (enExample) |
| DK (1) | DK1506171T3 (enExample) |
| EA (1) | EA007561B1 (enExample) |
| EG (1) | EG23693A (enExample) |
| ES (1) | ES2316755T3 (enExample) |
| IL (2) | IL165095A0 (enExample) |
| IS (1) | IS2650B (enExample) |
| MX (1) | MXPA04011459A (enExample) |
| MY (1) | MY129141A (enExample) |
| NO (1) | NO329559B1 (enExample) |
| NZ (1) | NZ536747A (enExample) |
| PL (1) | PL211695B1 (enExample) |
| PT (1) | PT1506171E (enExample) |
| SI (1) | SI1506171T1 (enExample) |
| TW (1) | TWI317733B (enExample) |
| UA (1) | UA79790C2 (enExample) |
| WO (1) | WO2003099774A1 (enExample) |
| ZA (1) | ZA200409400B (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2416792C (en) * | 2000-07-27 | 2010-02-09 | Teva Pharmaceutical Industries Ltd. | Crystalline and pure modafinil, and process of preparing the same |
| US6875893B2 (en) * | 2002-05-23 | 2005-04-05 | Cephalon, Inc. | Preparations of a sulfinyl acetamide |
| US6992219B2 (en) * | 2002-08-09 | 2006-01-31 | Cephalon France | Modafinil polymorphic forms |
| FR2849029B1 (fr) * | 2002-12-20 | 2005-03-18 | Lafon Labor | Procede de preparation et formes cristallines des enantiomeres optiques du modafinil. |
| MXPA05008088A (es) * | 2003-02-24 | 2005-09-21 | Mallinckrodt Inc | Proceso mejorado para preparar benzhidril tioacetamida. |
| US20040253308A1 (en) * | 2003-04-29 | 2004-12-16 | Barr Laboratories, Inc. | Surface-treated modafinil particles |
| US7368591B2 (en) | 2003-09-19 | 2008-05-06 | Cephalon France | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation |
| ATE410410T1 (de) * | 2003-10-23 | 2008-10-15 | Mallinckrodt Inc | Verbessertes verfahren zur herstellung von benzhydrylthioacetamid. |
| US20060086667A1 (en) * | 2004-09-13 | 2006-04-27 | Cephalon, Inc., U.S. Corporation | Methods for the separation of enantiomeric sulfinylacetamides |
| CN102225966B (zh) | 2004-10-19 | 2012-12-26 | 隆萨股份公司 | 用于固相肽合成的方法 |
| US20090123545A1 (en) * | 2005-07-21 | 2009-05-14 | Ron Eyal S | Rapid Onset and Short Term Modafinil Compositions and Methods of Use Thereof |
| WO2007027328A2 (en) * | 2005-07-28 | 2007-03-08 | University Of Iowa Research Foundation | Microbial sulfoxidation and amidation of benzhdrylsulfanyl carboxylic acids and uses thereof |
| WO2007033383A2 (en) * | 2005-09-14 | 2007-03-22 | Novetide, Ltd. | Process for production of bivalirudin |
| EP1973873A2 (en) * | 2005-12-09 | 2008-10-01 | Mallinckrodt Inc. | Processes for the preparation of modafinil and analogs thereof |
| CN100343228C (zh) * | 2006-02-17 | 2007-10-17 | 中国科学院上海有机化学研究所 | 高对映体选择性制备 2－二苯甲基亚磺酰基－乙酰胺单一对映体的方法 |
| US20070293702A1 (en) * | 2006-02-21 | 2007-12-20 | Viviana Braude | Novel crystalline forms of armodafinil and preparation thereof |
| WO2007103221A2 (en) * | 2006-03-01 | 2007-09-13 | Teva Pharmaceutical Industries Ltd. | An improved process for the preparation of armodafinil |
| GB0604233D0 (en) * | 2006-03-02 | 2006-04-12 | Syngenta Participations Ag | Process |
| CA2657409A1 (en) * | 2006-07-12 | 2008-01-17 | Elan Corporation, Plc | Nanoparticulate formulations of modafinil |
| WO2008021341A2 (en) * | 2006-08-14 | 2008-02-21 | Neurohealing Pharmaceuticals, Inc. | Modafinil-based treatment for premature ejaculation |
| WO2009025791A2 (en) * | 2007-08-16 | 2009-02-26 | Teva Pharmaceutical Industries Ltd. | Purification of armodafinil |
| US20100036164A1 (en) * | 2008-08-06 | 2010-02-11 | Srinivas Areveli | Preparation of armodafinil form i |
| CN102976985A (zh) * | 2011-09-07 | 2013-03-20 | 大连大学 | 一锅法合成二苯甲基亚磺酰基乙酰胺及其类似物的方法 |
| JP2017505266A (ja) * | 2014-02-06 | 2017-02-16 | ビレルドコールスネス アクティエボラーグ | 伸張可能な紙のスタンドアップポーチ |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1520812A (en) | 1975-10-02 | 1978-08-09 | Lafon Labor | Benzhydrylsulphinyl derivatives |
| GB1584462A (en) * | 1977-03-31 | 1981-02-11 | Lafon Labor | N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them |
| FR2593809B1 (fr) | 1986-01-31 | 1988-07-22 | Lafon Labor | Benzhydrylsulfinylacetamide, procede de preparation et utilisation en therapeutique |
| AU2001269531A1 (en) * | 2000-07-17 | 2002-01-30 | Takeda Chemical Industries Ltd. | Sulfone derivatives, process for their production and use thereof |
| CA2416792C (en) | 2000-07-27 | 2010-02-09 | Teva Pharmaceutical Industries Ltd. | Crystalline and pure modafinil, and process of preparing the same |
| IL143106A (en) | 2001-05-13 | 2005-11-20 | Chemagis Ltd | Process for the preparation of diphenylmethylthioacetamide |
| US6875893B2 (en) * | 2002-05-23 | 2005-04-05 | Cephalon, Inc. | Preparations of a sulfinyl acetamide |
| DE10245546B3 (de) * | 2002-09-30 | 2004-05-13 | Infineon Technologies Ag | Pseudostatische Speicherschaltung |
| JP3838972B2 (ja) * | 2002-12-25 | 2006-10-25 | Ｎｅｃエレクトロニクス株式会社 | 周波数検出回路及びデータ処理装置 |
-
2003
- 2003-05-22 US US10/443,327 patent/US6875893B2/en not_active Expired - Lifetime
- 2003-05-23 PT PT03729108T patent/PT1506171E/pt unknown
- 2003-05-23 PL PL373792A patent/PL211695B1/pl unknown
- 2003-05-23 TW TW092113924A patent/TWI317733B/zh not_active IP Right Cessation
- 2003-05-23 AR ARP030101796A patent/AR039857A1/es not_active Application Discontinuation
- 2003-05-23 DK DK03729108T patent/DK1506171T3/da active
- 2003-05-23 JP JP2004507432A patent/JP4351627B2/ja not_active Expired - Lifetime
- 2003-05-23 KR KR1020047018819A patent/KR100984571B1/ko not_active Expired - Fee Related
- 2003-05-23 CN CNB038118386A patent/CN100379721C/zh not_active Expired - Fee Related
- 2003-05-23 EA EA200401551A patent/EA007561B1/ru not_active IP Right Cessation
- 2003-05-23 CA CA2486533A patent/CA2486533C/en not_active Expired - Fee Related
- 2003-05-23 AT AT03729108T patent/ATE414058T1/de active
- 2003-05-23 UA UA20041210602A patent/UA79790C2/uk unknown
- 2003-05-23 ES ES03729108T patent/ES2316755T3/es not_active Expired - Lifetime
- 2003-05-23 IL IL16509503A patent/IL165095A0/xx unknown
- 2003-05-23 DE DE60324671T patent/DE60324671D1/de not_active Expired - Lifetime
- 2003-05-23 NZ NZ536747A patent/NZ536747A/en not_active IP Right Cessation
- 2003-05-23 MY MYPI20031924A patent/MY129141A/en unknown
- 2003-05-23 SI SI200331442T patent/SI1506171T1/sl unknown
- 2003-05-23 EP EP03729108A patent/EP1506171B1/en not_active Expired - Lifetime
- 2003-05-23 US US11/091,215 patent/US7057069B2/en not_active Expired - Fee Related
- 2003-05-23 MX MXPA04011459A patent/MXPA04011459A/es active IP Right Grant
- 2003-05-23 WO PCT/US2003/016379 patent/WO2003099774A1/en not_active Ceased
- 2003-05-23 BR BR0311242-0A patent/BR0311242A/pt not_active Application Discontinuation
-
2004
- 2004-11-08 IL IL165095A patent/IL165095A/en active IP Right Grant
- 2004-11-09 IS IS7523A patent/IS2650B/is unknown
- 2004-11-11 NO NO20044916A patent/NO329559B1/no not_active IP Right Cessation
- 2004-11-21 EG EGNA2004000127 patent/EG23693A/xx active
- 2004-11-22 ZA ZA2004/09400A patent/ZA200409400B/en unknown
-
2009
- 2009-02-04 CY CY20091100129T patent/CY1108747T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PL211695B1 (pl) | Sposób wytwarzania modafinilu | |
| HU223950B1 (hu) | Eljárás a racém, valamint az R-(-)- és S-(+)-N-[4-ciano-3-(trifluor-metil)-fenil]-3-[(4-fluor-fenil)-szulfonil]-2-hidroxi-2-metil-propánsavamid előállítására | |
| EP3580199B1 (fr) | Procédé de préparation monotope de composés organo-iodés | |
| JP2022034093A (ja) | ヨウ化アルカン誘導体の製造方法 | |
| US7674614B2 (en) | Method of optically resolving racemic alcohols with a bicyclooxaoctane or a bicycooxaoctene resolving reagents | |
| CA2468426A1 (en) | Process for preparing n-(4'-cyano-3'-trifluoromethylphenyl)-3-(4"-fluorophenylsulfonyl)-2-hydroxy-2-methylpropionamide | |
| CN1447801A (zh) | 制备杀虫氯噻唑的连续方法 | |
| EP1000933B1 (en) | Trifluoro methylthiomethyl benzene derivatives and process for producing the same | |
| AU2003233668B2 (en) | Preparations of a sulfinyl acetamide | |
| WO1998012171A1 (en) | Process for the preparation of 3-amino-2-hydroxy-1-propyl ethers | |
| JPWO1998012186A1 (ja) | グリシジルエーテルの製造法 | |
| KR19990015053A (ko) | 2-(4-할로메틸페닐)프로피온산의 제조방법 | |
| HK1072596B (en) | Preparations of a sulfinyl acetamide | |
| EP0301311B1 (en) | Process for preparing naproxen | |
| JP2014185120A (ja) | ルテオリンの製造方法 | |
| FR2519979A1 (fr) | Procede de preparation de trifluoromethoxy ou trifluoromethylthiophenylsulfones | |
| KR19990015050A (ko) | 페닐프로피온산 유도체의 제조방법 | |
| US20250250228A1 (en) | Methods for the preparation of 5-chloro-2-((ethoxycarbonyl)amino)-3-methylbenzoic acid | |
| KR100570279B1 (ko) | 코엔자임 Ｑｎ의 중간체 및 그 중간체의 제조방법 | |
| KR20020073980A (ko) | 디벤조티에핀 유도체의 신규 제조방법 | |
| EP0097550A1 (fr) | Procédé de préparation de dérivés de la cystamine à activité oncostatique | |
| JPWO1998012171A1 (ja) | ３−アミノ−２−ヒドロキシ−１−プロピルエーテルの製造法 | |
| JPS6121950B2 (enExample) | ||
| JPH09110742A (ja) | ２−フェニル−１，２，３−トリブロモプロパン類、３−ブロモ−２−フェニル−１−プロペン類およびこれらの製造法 |