PL2089511T3 - Rozrost in vitro komórek pochodzących z tkanki pępowinowej wykorzystujących mikronośniki - Google Patents

Rozrost in vitro komórek pochodzących z tkanki pępowinowej wykorzystujących mikronośniki

Info

Publication number
PL2089511T3
PL2089511T3 PL07867434T PL07867434T PL2089511T3 PL 2089511 T3 PL2089511 T3 PL 2089511T3 PL 07867434 T PL07867434 T PL 07867434T PL 07867434 T PL07867434 T PL 07867434T PL 2089511 T3 PL2089511 T3 PL 2089511T3
Authority
PL
Poland
Prior art keywords
microcarriers
postpartum
derived cells
vitro expansion
vitro
Prior art date
Application number
PL07867434T
Other languages
English (en)
Polish (pl)
Inventor
Alexander M Harmon
Klaudyne L S Hong
Anthony J Kihm
Anna Gosiewska
Original Assignee
Depuy Synthes Products Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Depuy Synthes Products Llc filed Critical Depuy Synthes Products Llc
Publication of PL2089511T3 publication Critical patent/PL2089511T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0607Non-embryonic pluripotent stem cells, e.g. MASC
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/16Particles; Beads; Granular material; Encapsulation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0605Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2531/00Microcarriers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins
    • C12N2533/52Fibronectin; Laminin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins
    • C12N2533/54Collagen; Gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Cell Biology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Sustainable Development (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
PL07867434T 2006-11-13 2007-11-13 Rozrost in vitro komórek pochodzących z tkanki pępowinowej wykorzystujących mikronośniki PL2089511T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86555806P 2006-11-13 2006-11-13
PCT/US2007/023846 WO2008060541A2 (en) 2006-11-13 2007-11-13 In vitro expansion of postpartum-derived cells using microcarriers
EP07867434.8A EP2089511B1 (en) 2006-11-13 2007-11-13 In vitro expansion of postpartum-derived cells using microcarriers

Publications (1)

Publication Number Publication Date
PL2089511T3 true PL2089511T3 (pl) 2015-02-27

Family

ID=39402235

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07867434T PL2089511T3 (pl) 2006-11-13 2007-11-13 Rozrost in vitro komórek pochodzących z tkanki pępowinowej wykorzystujących mikronośniki

Country Status (9)

Country Link
US (1) US9102915B2 (https=)
EP (1) EP2089511B1 (https=)
JP (2) JP5670053B2 (https=)
CN (1) CN101611139B (https=)
AU (1) AU2007319820B2 (https=)
CA (1) CA2669589C (https=)
ES (1) ES2524443T3 (https=)
PL (1) PL2089511T3 (https=)
WO (1) WO2008060541A2 (https=)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003008535A2 (en) * 2001-07-20 2003-01-30 Technion Research And Development Foundation Ltd. Methods of generating human cardiac cells and tissues and uses thereof
US9592258B2 (en) 2003-06-27 2017-03-14 DePuy Synthes Products, Inc. Treatment of neurological injury by administration of human umbilical cord tissue-derived cells
US7875272B2 (en) 2003-06-27 2011-01-25 Ethicon, Incorporated Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells
US9572840B2 (en) 2003-06-27 2017-02-21 DePuy Synthes Products, Inc. Regeneration and repair of neural tissue using postpartum-derived cells
WO2005001080A2 (en) 2003-06-27 2005-01-06 Ethicon, Incorporated Postpartum-derived cells for use in treatment of disease of the heart and circulatory system
WO2006071794A2 (en) * 2004-12-23 2006-07-06 Ethicon Incorporated Postpartum cells derived from umbilical cord tissue, and methods of making and using the same
US8790637B2 (en) 2003-06-27 2014-07-29 DePuy Synthes Products, LLC Repair and regeneration of ocular tissue using postpartum-derived cells
US8491883B2 (en) 2003-06-27 2013-07-23 Advanced Technologies And Regenerative Medicine, Llc Treatment of amyotrophic lateral sclerosis using umbilical derived cells
US8518390B2 (en) 2003-06-27 2013-08-27 Advanced Technologies And Regenerative Medicine, Llc Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells
WO2006071778A2 (en) 2004-12-23 2006-07-06 Ethicon Incorporated Treatment of parkinson's disease and related disorders using postpartum derived cells
DK1957633T3 (en) 2005-10-13 2014-03-17 Anthrogenesis Corp Immunomodulation USING PLACE SPEECH STEM CELLS
WO2007070870A1 (en) 2005-12-16 2007-06-21 Ethicon, Inc. Compositions and methods for inhibiting adverse immune response in histocompatibility-mismatched transplantation
JP5179376B2 (ja) * 2005-12-19 2013-04-10 エシコン・インコーポレイテッド ローラーボトルでの分娩後取り出し細胞の体外増殖
US9125906B2 (en) 2005-12-28 2015-09-08 DePuy Synthes Products, Inc. Treatment of peripheral vascular disease using umbilical cord tissue-derived cells
PT2471904T (pt) 2005-12-29 2019-02-25 Celularity Inc População de células estaminais placentárias
WO2008045498A1 (en) 2006-10-12 2008-04-17 Ethicon, Inc. Kidney-derived cells and methods of use in tissue repair and regeneration
PL2089511T3 (pl) 2006-11-13 2015-02-27 Depuy Synthes Products Llc Rozrost in vitro komórek pochodzących z tkanki pępowinowej wykorzystujących mikronośniki
EP3763376A1 (en) 2007-02-12 2021-01-13 Celularity, Inc. Treatment of inflammatory diseases using placental stem cells
US8399253B2 (en) * 2007-04-28 2013-03-19 Hyunjin Yang Proliferation culture methods using micro-scaffolds for regulations of cell-to-cell signals
NZ599825A (en) 2007-09-28 2014-10-31 Anthrogenesis Corp Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells
PT103843B (pt) * 2007-10-04 2008-08-12 Medinfar Produtos Farmaceutico Método de isolamento de células precursoras a partir do cordão umbilical humano
JP5323845B2 (ja) 2007-10-05 2013-10-23 エシコン・インコーポレイテッド ヒト臍帯組織由来細胞を用いた腎組織の修復および再建
US8236538B2 (en) * 2007-12-20 2012-08-07 Advanced Technologies And Regenerative Medicine, Llc Methods for sterilizing materials containing biologically active agents
US20090233334A1 (en) * 2008-03-11 2009-09-17 Excellgene Sa Cell cultivation and production of recombinant proteins by means of an orbital shake bioreactor system with disposable bags at the 1,500 liter scale
US9458431B2 (en) 2008-03-17 2016-10-04 Agency For Science, Technology And Research Microcarriers for stem cell culture
JP2011514169A (ja) 2008-03-17 2011-05-06 エージェンシー フォー サイエンス,テクノロジー アンド リサーチ 幹細胞培養のためのマイクロキャリア
US8691569B2 (en) * 2008-03-17 2014-04-08 Agency For Science, Technology And Research Microcarriers for stem cell culture
US8828720B2 (en) * 2008-03-17 2014-09-09 Agency For Science, Technology And Research Microcarriers for stem cell culture
US20120219531A1 (en) * 2008-03-17 2012-08-30 Agency For Science, Technology And Research Microcarriers for Stem Cell Culture
US20120028352A1 (en) * 2008-03-17 2012-02-02 Agency For Science, Technology And Research Microcarriers for Stem Cell Culture
KR20240052847A (ko) 2008-08-20 2024-04-23 셀룰래리티 인코포레이티드 개선된 세포 조성물 및 그의 제조 방법
WO2010021715A1 (en) 2008-08-20 2010-02-25 Anthrogenesis Corporation Treatment of stroke using isolated placental cells
CA2734446C (en) 2008-08-22 2017-06-20 Anthrogenesis Corporation Methods and compositions for treatment of bone defects with placental cell populations
AU2009316541B2 (en) 2008-11-19 2015-08-06 Celularity Inc. Amnion derived adherent cells
US20100151575A1 (en) * 2008-12-15 2010-06-17 Colter David C Method of Making Conditioned Media from Kidney Derived Cells
CN102387807A (zh) 2008-12-19 2012-03-21 先进科技及再生医学有限责任公司 肺部疾病和病症的治疗
US10179900B2 (en) 2008-12-19 2019-01-15 DePuy Synthes Products, Inc. Conditioned media and methods of making a conditioned media
SG174551A1 (en) 2009-03-26 2011-10-28 Ethicon Inc Human umbilical cord tissue cells as therapy for alzheimer' s disease
US20100247495A1 (en) * 2009-03-30 2010-09-30 Tom Ichim Treatment of Muscular Dystrophy
US20120189702A1 (en) * 2009-08-06 2012-07-26 Albert Einstein College Of Medicine Of Yeshiva University Cell therapy for treatment of liver failure
US8278101B2 (en) * 2009-12-07 2012-10-02 Synthecon, Inc. Stem cell bioprocessing and cell expansion
DK3284818T3 (da) 2010-01-26 2022-06-20 Celularity Inc Behandling af knoglerelateret kræft ved hjælp af placenta stamceller
LT2556145T (lt) 2010-04-07 2016-11-10 Anthrogenesis Corporation Angiogenezė naudojant placentos kamienines ląsteles
MX2012011543A (es) 2010-04-08 2013-05-06 Anthrogenesis Corp Tratamiento de sarcoidosis empleando celulas madre placentarias.
EP2575913B1 (en) 2010-05-25 2018-07-25 Cook Biotech Incorporated Methods, substrates, and systems useful for cell seeding of medical grafts
CN102146356A (zh) * 2010-06-24 2011-08-10 辽宁成大生物股份有限公司 一种再生微载体的方法
ES2666746T3 (es) 2010-07-13 2018-05-07 Anthrogenesis Corporation Métodos para generar linfocitos citolíticos naturales
US10240121B2 (en) 2010-08-16 2019-03-26 Kiyatec Inc. Bioreactor system
US8969315B2 (en) 2010-12-31 2015-03-03 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory RNA molecules
JP2012165719A (ja) * 2011-02-16 2012-09-06 National Institute Of Advanced Industrial Science & Technology 擬微小重力環境下での三次元癌組織モデルの構築方法
JP6104896B2 (ja) 2011-06-01 2017-03-29 アントフロゲネシス コーポレーション 胎盤幹細胞を使用する疼痛の治療
US20140170748A1 (en) * 2012-12-14 2014-06-19 DePuy Synthes Products, LLC Nutrient Enriched Media for hUTC Growth
CN115137753A (zh) 2013-02-05 2022-10-04 细胞结构公司 来自胎盘的自然杀伤细胞
US10895524B2 (en) * 2013-02-19 2021-01-19 Abbott Point Of Care, Inc. Biologic fluid sample analysis cartridge with non-reflective beads
JP2016526387A (ja) * 2013-06-24 2016-09-05 アントフロゲネシス コーポレーション 細胞培養のための細胞外マトリクス組成物ビーズ
JP6913094B2 (ja) * 2015-12-22 2021-08-04 コーニング インコーポレイテッド 細胞分離器具およびそれを使用する方法
KR102211270B1 (ko) 2016-01-14 2021-02-04 디퍼이 신테스 프로덕츠, 인코포레이티드 Hutc의 동결보존을 위한 조성물 및 방법
CN109312284B (zh) 2016-05-31 2021-10-22 康宁股份有限公司 用于培养细胞的减少叶轮摆动的容器和旋转烧瓶
EP3528630A4 (en) * 2016-10-21 2020-05-13 Georgia Tech Research Corporation METHODS AND SYSTEMS FOR T-CELL EXPANSION
WO2018186185A1 (ja) 2017-04-06 2018-10-11 日機装株式会社 細胞の培養方法、細胞支持複合体の製造方法、培養細胞及び細胞支持複合体
WO2019181920A1 (ja) * 2018-03-22 2019-09-26 日機装株式会社 細胞の培養方法、細胞支持複合体の製造方法、培養細胞および細胞支持複合体
KR20210134323A (ko) 2019-01-31 2021-11-09 베이징 사이토니체 바이오테크놀로지 씨오., 엘티디. 줄기 세포의 대규모 제조를 위한 3차원 배양 방법
CN111424011A (zh) * 2020-04-17 2020-07-17 深圳市旷逸生物科技有限公司 一种能够维持脐带间充质干细胞细胞形态的三维培养方法
US20230034857A1 (en) * 2020-09-15 2023-02-02 Lg Chem, Ltd. Microcarrier for cell culture and method for preparing the same
JPWO2024253069A1 (https=) * 2023-06-06 2024-12-12

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1220832B (de) * 1964-09-22 1966-07-14 Siemens Ag Ziehduese zum Ziehen von Halbleiterkristallen aus einer Schmelze
US3665061A (en) 1969-07-16 1972-05-23 United States Banknote Corp Process for producing collagen sponges
US4216144A (en) 1977-10-20 1980-08-05 Ashmead H H Soluble iron proteinates
JPS6040439B2 (ja) 1978-03-29 1985-09-11 大正製薬株式会社 ヒドロコルチゾン誘導体
US4487865A (en) 1983-12-15 1984-12-11 Biomatrix, Inc. Polymeric articles modified with hyaluronate
US5266476A (en) * 1985-06-18 1993-11-30 Yeda Research & Development Co., Ltd. Fibrous matrix for in vitro cell cultivation
US4963489A (en) * 1987-04-14 1990-10-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US5266480A (en) * 1986-04-18 1993-11-30 Advanced Tissue Sciences, Inc. Three-dimensional skin culture system
US4925677A (en) 1988-08-31 1990-05-15 Theratech, Inc. Biodegradable hydrogel matrices for the controlled release of pharmacologically active agents
US5284766A (en) * 1989-02-10 1994-02-08 Kao Corporation Bed material for cell culture
NL9100038A (nl) 1991-01-11 1992-08-03 Stamicarbon Enzym-gekatalyseerde bereiding van optisch aktieve carbonzuren.
DE4406073A1 (de) 1994-02-24 1995-08-31 Univ Ludwigs Albert Verfahren zur Herstellung von humanen, klonogenen Fibroblasten, Verfahren zur Gentransfizierung von Fibroblasten und so erhaltene Fibroblasten
US5919702A (en) 1996-10-23 1999-07-06 Advanced Tissue Science, Inc. Production of cartilage tissue using cells isolated from Wharton's jelly
JP2002513383A (ja) 1997-05-21 2002-05-08 スローン−ケタリング・インスティテュート・フォー・キャンサー・リサーチ 患者の脳組織でのアスコルビン酸の濃度を増加させる方法
US7560280B2 (en) * 2000-11-03 2009-07-14 Kourion Therapeutics Gmbh Human cord blood derived unrestricted somatic stem cells (USSC)
EP2316919B1 (en) * 2001-02-14 2015-10-07 Anthrogenesis Corporation Post-partum mammalian placenta, its use and placental stem cells therefrom
EP1384786B1 (en) 2001-04-02 2010-01-27 Glycomedics, Inc. Process for producing oligosaccharide chains
AU2003217350A1 (en) * 2002-02-08 2003-09-02 University Of Chile Proliferated cell lines and uses thereof
ES2287447T3 (es) 2002-02-19 2007-12-16 Medipost, Co., Ltd. Metodos de aislamiento y expansion del cultivo de celulas troncales/madre mesenquimatosas a partir de sangre del cordon umbilical, y metodo de diferenciacion de celulas troncales/madre mesenquimatosas derivadas de sangre del cordon umbilical en diversos tejidos mesenquimatosos.
JP2003259862A (ja) * 2002-03-12 2003-09-16 Fuji Photo Film Co Ltd 細胞培養担体
AU2003265094A1 (en) 2002-08-26 2004-03-11 Neuronova Ab Method for culturing stem cells
GB0222846D0 (en) * 2002-10-03 2002-11-06 Choo Yen Cell culture
US7875272B2 (en) * 2003-06-27 2011-01-25 Ethicon, Incorporated Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells
US8790637B2 (en) * 2003-06-27 2014-07-29 DePuy Synthes Products, LLC Repair and regeneration of ocular tissue using postpartum-derived cells
WO2005001080A2 (en) 2003-06-27 2005-01-06 Ethicon, Incorporated Postpartum-derived cells for use in treatment of disease of the heart and circulatory system
WO2006071794A2 (en) * 2004-12-23 2006-07-06 Ethicon Incorporated Postpartum cells derived from umbilical cord tissue, and methods of making and using the same
US9572840B2 (en) 2003-06-27 2017-02-21 DePuy Synthes Products, Inc. Regeneration and repair of neural tissue using postpartum-derived cells
CA2532754A1 (en) 2003-07-17 2005-02-03 Global Cell Solutions, Llc Automated cell culture system and process
JP4575654B2 (ja) * 2003-09-05 2010-11-04 エスエス製薬株式会社 溶解性と流動性を改善した医薬組成物
DE102004043256B4 (de) * 2004-09-07 2013-09-19 Rheinische Friedrich-Wilhelms-Universität Bonn Skalierbarer Prozess zur Kultivierung undifferenzierter Stammzellen in Suspension
AU2005302516A1 (en) 2004-10-29 2006-05-11 Centocor, Inc. Chemically defined media compositions
US20060166361A1 (en) 2004-12-21 2006-07-27 Agnieszka Seyda Postpartum cells derived from placental tissue, and methods of making, culturing, and using the same
WO2006071778A2 (en) * 2004-12-23 2006-07-06 Ethicon Incorporated Treatment of parkinson's disease and related disorders using postpartum derived cells
WO2006088867A2 (en) * 2005-02-15 2006-08-24 Medistem Laboratories, Incorporated Method for expansion of stem cells
CN103356706B (zh) 2005-03-31 2016-01-20 斯丹姆涅恩有限公司 促进无疤愈合或改善皮肤外观的美容制剂
WO2007070870A1 (en) * 2005-12-16 2007-06-21 Ethicon, Inc. Compositions and methods for inhibiting adverse immune response in histocompatibility-mismatched transplantation
JP5179376B2 (ja) * 2005-12-19 2013-04-10 エシコン・インコーポレイテッド ローラーボトルでの分娩後取り出し細胞の体外増殖
EP2366775B1 (en) * 2006-03-23 2015-04-22 Pluristem Ltd. Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy
CA2893679C (en) 2006-06-26 2018-10-30 Lifescan, Inc. Conditioned medium for pluripotent stem cell culture
PL2089511T3 (pl) 2006-11-13 2015-02-27 Depuy Synthes Products Llc Rozrost in vitro komórek pochodzących z tkanki pępowinowej wykorzystujących mikronośniki
JP6095893B2 (ja) 2008-12-19 2017-03-15 デピュイ・シンセス・プロダクツ・インコーポレイテッド 傷害後の神経組織の再生および修復
US10179900B2 (en) 2008-12-19 2019-01-15 DePuy Synthes Products, Inc. Conditioned media and methods of making a conditioned media
BRPI0923177A2 (pt) 2008-12-19 2020-08-25 Advanced Technologies And Regenerative Medicine, Llc usos de composições para tratar dor neuropática e espacidade, as referidas composições, e kit
SG174551A1 (en) * 2009-03-26 2011-10-28 Ethicon Inc Human umbilical cord tissue cells as therapy for alzheimer' s disease

Also Published As

Publication number Publication date
CA2669589C (en) 2016-01-12
WO2008060541A2 (en) 2008-05-22
US9102915B2 (en) 2015-08-11
CN101611139A (zh) 2009-12-23
CA2669589A1 (en) 2008-05-22
AU2007319820B2 (en) 2013-09-05
EP2089511B1 (en) 2014-09-17
ES2524443T3 (es) 2014-12-09
AU2007319820A1 (en) 2008-05-22
JP2014236755A (ja) 2014-12-18
US20080166328A1 (en) 2008-07-10
WO2008060541A3 (en) 2008-08-28
JP5670053B2 (ja) 2015-02-18
JP2010508851A (ja) 2010-03-25
CN101611139B (zh) 2012-07-04
EP2089511A2 (en) 2009-08-19

Similar Documents

Publication Publication Date Title
PL2089511T3 (pl) Rozrost in vitro komórek pochodzących z tkanki pępowinowej wykorzystujących mikronośniki
IL276146A (en) Laboratory methods for increasing the vitality of the cells of the immune system
IL194438A (en) Diarrhylthiohydantoin Compounds, Pharmaceuticals Containing Them, Syntheses Methods and In Vitro Methods for Contacting them with Mammalian Cells
IL221384A0 (en) Improving il-15 and il-15r-alpha for expression in mammalian cells
SG10201405107YA (en) Compositions and methods useful for culturing differentiable cells
IL200622A0 (en) Use of copper and glutamate in cell culture for production of polypeptides
GB0605450D0 (en) Cell co-culture
EP2064324A4 (en) SUBSTRATES FOR CELL CULTURE AND MANUFACTURING METHOD THEREFOR
IL241906A0 (en) Methods for the production and uses of pluripotent cell populations and differentiated cell populations
EP2089507A4 (en) DEVICES AND METHODS PARTICULARLY EFFECTIVE IN CELL CULTURE
PL2046946T3 (pl) Hodowla pluripotencjalnych komórek macierzystych
PL3323883T3 (pl) Zdefiniowane powierzchnie do hodowli komórkowej i sposoby użycia
SG10201510384UA (en) Cell culture improvements
PL3524316T3 (pl) Urządzenia elektroporujące do elektroporowania komórek u ssaków
IL194894A0 (en) Substrate for the growth of cultured cells in three dimensions
PL2132562T3 (pl) Sposób oceniania komórek i hodowli komórkowych
GB0613756D0 (en) Cell culture medium
IL191868A (en) Extracellular method to cause planned cell death in a target cell
GB0622394D0 (en) Differentiation of pluripotent cells
EP2227540A4 (en) DIFFERENTIATION OF HUMAN CELLS
GB0600972D0 (en) Enrichment of cells
IL220165B (en) A method for 3D co-culture of podocytes and endothelial cells and an in vitro system suitable for co-culture
ZA200902007B (en) In vivo transformation of pancreatic acinar cells into insulin-producing cells
IL194524A0 (en) Three dimensional cell culture
IL196803A0 (en) Differential labeling of cells