PL2078017T3 - Fluorowane pochodne katarantyny, ich wytwarzanie i ich zastosowanie jako prekursorów dimerycznych alkaloidów Vinca - Google Patents
Fluorowane pochodne katarantyny, ich wytwarzanie i ich zastosowanie jako prekursorów dimerycznych alkaloidów VincaInfo
- Publication number
- PL2078017T3 PL2078017T3 PL07820424T PL07820424T PL2078017T3 PL 2078017 T3 PL2078017 T3 PL 2078017T3 PL 07820424 T PL07820424 T PL 07820424T PL 07820424 T PL07820424 T PL 07820424T PL 2078017 T3 PL2078017 T3 PL 2078017T3
- Authority
- PL
- Poland
- Prior art keywords
- utilisation
- preparation
- fluorinated
- derivatives
- alkaloid precursors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Plant Substances (AREA)
- Steroid Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82624506P | 2006-09-20 | 2006-09-20 | |
| FR0608226A FR2905949B1 (fr) | 2006-09-20 | 2006-09-20 | Derives fluores de catharanthine, leur preparation et leur utilisation comme precurseurs d'alcaloides dimeres de vinca |
| EP07820424A EP2078017B9 (en) | 2006-09-20 | 2007-09-20 | Fluorinated catharanthine derivatives, their preparation and their utilisation as vinca dimeric alkaloid precursors |
| PCT/EP2007/059991 WO2008034882A1 (en) | 2006-09-20 | 2007-09-20 | Fluorinated catharanthine derivatives, their preparation and their utilisation as vinca dimeric alkaloid precursors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2078017T3 true PL2078017T3 (pl) | 2011-02-28 |
Family
ID=37982436
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07820424T PL2078017T3 (pl) | 2006-09-20 | 2007-09-20 | Fluorowane pochodne katarantyny, ich wytwarzanie i ich zastosowanie jako prekursorów dimerycznych alkaloidów Vinca |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US8101748B2 (pl) |
| EP (1) | EP2078017B9 (pl) |
| JP (1) | JP5280364B2 (pl) |
| KR (1) | KR20090063256A (pl) |
| CN (1) | CN101522679B (pl) |
| AT (1) | ATE478871T1 (pl) |
| AU (1) | AU2007298920B2 (pl) |
| BR (1) | BRPI0717063A2 (pl) |
| CA (1) | CA2664040A1 (pl) |
| DE (1) | DE602007008748D1 (pl) |
| ES (1) | ES2349387T3 (pl) |
| FR (1) | FR2905949B1 (pl) |
| IL (1) | IL197640A (pl) |
| MA (1) | MA31134B1 (pl) |
| MX (1) | MX2009003121A (pl) |
| NO (1) | NO20091491L (pl) |
| NZ (1) | NZ575884A (pl) |
| PL (1) | PL2078017T3 (pl) |
| PT (1) | PT2078017E (pl) |
| RU (1) | RU2448957C2 (pl) |
| TN (1) | TN2009000097A1 (pl) |
| WO (1) | WO2008034882A1 (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8940754B2 (en) | 2010-02-22 | 2015-01-27 | The Scripps Research Institute | 10′-fluorinated Vinca alkaloids provide enhanced biological activity against MDR cancer cells |
| CN105121447B (zh) * | 2013-04-19 | 2018-02-02 | 暨南大学 | 长春碱类衍生物及其制备方法和应用 |
| CN105503907B (zh) * | 2016-01-18 | 2018-01-09 | 北京大学 | 对映选择性合成Vinca类生物碱的方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU180924B (en) * | 1977-05-20 | 1983-05-30 | Richter Gedeon Vegyeszet | Process for producing leurosine-type alkaloides |
| FR2632643B1 (fr) * | 1988-06-10 | 1990-09-07 | Adir | Nouveau procede de preparation de derives n-(vinblastinoyl-23) d'acide amino-1 methylphosphonique |
| JPH0341081A (ja) * | 1989-07-10 | 1991-02-21 | Mitsui Petrochem Ind Ltd | 二量体アルカロイド類の製造方法 |
| FR2707988B1 (fr) * | 1993-07-21 | 1995-10-13 | Pf Medicament | Nouveaux dérivés antimitotiques des alcaloïdes binaires du catharantus rosesus, leur procédé de préparation et les compositions pharmaceutiques les comprenant. |
| FR2761990B1 (fr) * | 1997-04-10 | 1999-06-25 | Pf Medicament | Derives halogenes antimitotiques d'alcaloides de vinca |
| FR2779146B1 (fr) * | 1998-06-02 | 2002-01-18 | Roowin | Nouveaux derives de vinca-alcaloides et procedes de preparation |
| CN1218950C (zh) * | 2004-02-18 | 2005-09-14 | 东北林业大学 | 一种长春碱的生产方法 |
-
2006
- 2006-09-20 FR FR0608226A patent/FR2905949B1/fr not_active Expired - Fee Related
-
2007
- 2007-09-20 ES ES07820424T patent/ES2349387T3/es active Active
- 2007-09-20 US US12/442,193 patent/US8101748B2/en not_active Expired - Fee Related
- 2007-09-20 PL PL07820424T patent/PL2078017T3/pl unknown
- 2007-09-20 AT AT07820424T patent/ATE478871T1/de not_active IP Right Cessation
- 2007-09-20 PT PT07820424T patent/PT2078017E/pt unknown
- 2007-09-20 DE DE602007008748T patent/DE602007008748D1/de active Active
- 2007-09-20 CA CA002664040A patent/CA2664040A1/en not_active Abandoned
- 2007-09-20 JP JP2009528728A patent/JP5280364B2/ja not_active Expired - Fee Related
- 2007-09-20 CN CN2007800384442A patent/CN101522679B/zh not_active Expired - Fee Related
- 2007-09-20 NZ NZ575884A patent/NZ575884A/en not_active IP Right Cessation
- 2007-09-20 AU AU2007298920A patent/AU2007298920B2/en not_active Ceased
- 2007-09-20 KR KR1020097007521A patent/KR20090063256A/ko not_active Application Discontinuation
- 2007-09-20 BR BRPI0717063-7A patent/BRPI0717063A2/pt not_active IP Right Cessation
- 2007-09-20 WO PCT/EP2007/059991 patent/WO2008034882A1/en active Application Filing
- 2007-09-20 EP EP07820424A patent/EP2078017B9/en active Active
- 2007-09-20 MX MX2009003121A patent/MX2009003121A/es active IP Right Grant
- 2007-09-20 RU RU2009113535/04A patent/RU2448957C2/ru not_active IP Right Cessation
-
2009
- 2009-03-17 IL IL197640A patent/IL197640A/en not_active IP Right Cessation
- 2009-03-19 TN TN2009000097A patent/TN2009000097A1/fr unknown
- 2009-04-03 MA MA31759A patent/MA31134B1/fr unknown
- 2009-04-16 NO NO20091491A patent/NO20091491L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20100093997A1 (en) | 2010-04-15 |
| CA2664040A1 (en) | 2008-03-27 |
| US8101748B2 (en) | 2012-01-24 |
| CN101522679B (zh) | 2013-12-18 |
| RU2448957C2 (ru) | 2012-04-27 |
| RU2009113535A (ru) | 2010-10-27 |
| ES2349387T3 (es) | 2010-12-30 |
| JP5280364B2 (ja) | 2013-09-04 |
| MA31134B1 (fr) | 2010-02-01 |
| AU2007298920B2 (en) | 2012-03-08 |
| FR2905949A1 (fr) | 2008-03-21 |
| WO2008034882A1 (en) | 2008-03-27 |
| EP2078017B1 (en) | 2010-08-25 |
| AU2007298920A1 (en) | 2008-03-27 |
| ATE478871T1 (de) | 2010-09-15 |
| JP2010504303A (ja) | 2010-02-12 |
| BRPI0717063A2 (pt) | 2013-10-15 |
| EP2078017B9 (en) | 2011-09-07 |
| IL197640A0 (en) | 2009-12-24 |
| TN2009000097A1 (en) | 2010-08-19 |
| EP2078017A1 (en) | 2009-07-15 |
| NO20091491L (no) | 2009-05-13 |
| KR20090063256A (ko) | 2009-06-17 |
| MX2009003121A (es) | 2009-07-31 |
| IL197640A (en) | 2013-03-24 |
| PT2078017E (pt) | 2010-11-09 |
| NZ575884A (en) | 2011-09-30 |
| CN101522679A (zh) | 2009-09-02 |
| FR2905949B1 (fr) | 2008-11-21 |
| DE602007008748D1 (de) | 2010-10-07 |
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