PL1988081T3 - Inhibitor wiązania sfingozyno-1-fosforanu - Google Patents
Inhibitor wiązania sfingozyno-1-fosforanuInfo
- Publication number
- PL1988081T3 PL1988081T3 PL07713881T PL07713881T PL1988081T3 PL 1988081 T3 PL1988081 T3 PL 1988081T3 PL 07713881 T PL07713881 T PL 07713881T PL 07713881 T PL07713881 T PL 07713881T PL 1988081 T3 PL1988081 T3 PL 1988081T3
- Authority
- PL
- Poland
- Prior art keywords
- sphingosine
- phosphate
- binding inhibitor
- inhibitor
- binding
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
- DUYSYHSSBDVJSM-KRWOKUGFSA-N sphingosine 1-phosphate Chemical compound CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)COP(O)(O)=O DUYSYHSSBDVJSM-KRWOKUGFSA-N 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Transplantation (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006028973 | 2006-02-06 | ||
EP07713881A EP1988081B1 (en) | 2006-02-06 | 2007-02-06 | Binding inhibitor of sphingosine-1-phosphate |
PCT/JP2007/052052 WO2007091570A1 (ja) | 2006-02-06 | 2007-02-06 | スフィンゴシン-1-リン酸結合阻害物質 |
Publications (1)
Publication Number | Publication Date |
---|---|
PL1988081T3 true PL1988081T3 (pl) | 2013-03-29 |
Family
ID=38345166
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL07713881T PL1988081T3 (pl) | 2006-02-06 | 2007-02-06 | Inhibitor wiązania sfingozyno-1-fosforanu |
Country Status (9)
Country | Link |
---|---|
US (1) | US7994204B2 (pl) |
EP (1) | EP1988081B1 (pl) |
JP (1) | JP5218737B2 (pl) |
CN (1) | CN101415687B (pl) |
ES (1) | ES2393621T3 (pl) |
HK (1) | HK1131127A1 (pl) |
PL (1) | PL1988081T3 (pl) |
RU (1) | RU2395499C2 (pl) |
WO (1) | WO2007091570A1 (pl) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1993333B (zh) * | 2004-08-04 | 2012-08-01 | 大正制药株式会社 | 三唑衍生物 |
EP1988083B1 (en) * | 2006-02-03 | 2014-04-02 | Taisho Pharmaceutical Co., Ltd. | Triazole derivative |
EP1988081B1 (en) | 2006-02-06 | 2012-10-17 | Taisho Pharmaceutical Co., Ltd | Binding inhibitor of sphingosine-1-phosphate |
JP5311057B2 (ja) * | 2007-08-01 | 2013-10-09 | 大正製薬株式会社 | S1p1結合阻害物質 |
WO2009108633A2 (en) * | 2008-02-25 | 2009-09-03 | Expression Drug Designs, Llc. | Sphingosine 1-phosphate antagonism |
US8212010B2 (en) | 2008-02-25 | 2012-07-03 | Expression Drug Designs, Llc | Sphingosine 1-phosphate antagonism |
KR101911105B1 (ko) * | 2010-09-21 | 2018-10-23 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 제약 조성물 |
WO2012124782A1 (ja) * | 2011-03-16 | 2012-09-20 | 武田薬品工業株式会社 | 縮合複素環化合物 |
EP2817317A1 (en) * | 2012-02-21 | 2014-12-31 | Allergan, Inc. | Phenoxy derivatives as sphingosine 1-phosphate (s1p) receptor modulators |
CA2865252A1 (en) * | 2012-02-21 | 2013-08-29 | Allergan, Inc. | Sulfinylbenzyl and thiobenzyl derivatives as sphingosine 1-phosphate (s1p) receptor modulators |
EP2817290A1 (en) * | 2012-02-21 | 2014-12-31 | Allergan, Inc. | Phenoxy-azetidine derivatives as sphingosine 1-phosphate (s1p) receptor modulators |
PT2984073T (pt) | 2013-02-08 | 2019-01-21 | Gen Mills Inc | Produto alimentar com baixo teor de sódio |
RS59140B1 (sr) | 2013-10-21 | 2019-09-30 | Merck Patent Gmbh | Heteroarilna jedinjenja kao inhibitori btk i njihova upotreba |
SG11202006255UA (en) | 2018-02-02 | 2020-07-29 | Univ Kyoto | Medicine for preventing or treating ophthalmic disease associated with enhanced intraocular neovascularization and/or intraocular vascular permeability |
Family Cites Families (41)
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US614463A (en) * | 1898-11-22 | grove | ||
DE69033905T2 (de) * | 1989-10-30 | 2003-02-06 | Starsight Telecast Inc | Schnittstelle zwischen kabelfernsehdekoder und fernsehzubehör |
JPH05194412A (ja) * | 1991-12-28 | 1993-08-03 | Advance Co Ltd | ジアゾリン化合物 |
GB9202791D0 (en) | 1992-02-11 | 1992-03-25 | British Bio Technology | Compounds |
DK0786455T3 (da) * | 1994-09-26 | 2004-03-29 | Shionogi & Co | Imidazolderivater |
US7194753B1 (en) * | 1999-04-15 | 2007-03-20 | Microsoft Corporation | System and method for efficiently tuning to channels of a variety of different broadcast types |
AU2001246999A1 (en) | 2000-04-06 | 2001-10-23 | Astrazeneca Ab | New neurokinin antagonists for use as medicaments |
JP2004507552A (ja) | 2000-08-31 | 2004-03-11 | メルク エンド カムパニー インコーポレーテッド | 免疫調節剤としてのリン酸誘導体 |
US7131111B2 (en) * | 2001-01-19 | 2006-10-31 | Sun Microsystems, Inc. | Development of manifest for java embedded server bundle |
JP2002212070A (ja) | 2001-01-24 | 2002-07-31 | Ono Pharmaceut Co Ltd | アスパラギン酸誘導体を有効成分として含有するスフィンゴシン−1−リン酸拮抗剤 |
US20020166123A1 (en) * | 2001-03-02 | 2002-11-07 | Microsoft Corporation | Enhanced television services for digital video recording and playback |
JP2002332278A (ja) | 2001-05-08 | 2002-11-22 | Human Science Shinko Zaidan | Edg受容体拮抗作用を有する複素環誘導体 |
DE60230262D1 (de) | 2001-05-10 | 2009-01-22 | Ono Pharmaceutical Co | Carbonsäurederivate und diese als wirkstoff enthaltende arzneimittel |
WO2002093901A2 (en) * | 2001-05-11 | 2002-11-21 | Scientific-Atlanta, Inc. | Managing time shift buffers |
GB0113524D0 (en) | 2001-06-04 | 2001-07-25 | Hoffmann La Roche | Pyrazole derivatives |
DE10130397A1 (de) * | 2001-06-23 | 2003-01-09 | Bayer Cropscience Gmbh | Herbizide substituierte Pyridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Herbzide und Pflanzenwachstumsregulatoren |
US7512964B2 (en) * | 2001-06-29 | 2009-03-31 | Cisco Technology | System and method for archiving multiple downloaded recordable media content |
JP4035759B2 (ja) | 2001-11-06 | 2008-01-23 | 独立行政法人産業技術総合研究所 | アミノアルコールリン酸化合物、製造方法、及びその利用方法 |
US20030106056A1 (en) * | 2001-11-30 | 2003-06-05 | Naimpally Saiprasad V. | System and method for carriage of program-related information in vertical blanking interval (VBI) of video output signal of program guide-Equipped video equipment |
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WO2003074008A2 (en) | 2002-03-01 | 2003-09-12 | Merck & Co., Inc. | Aminoalkylphosphonates and related compounds as edg receptor agonists |
US7309721B2 (en) | 2002-03-01 | 2007-12-18 | Merck + Co., Inc. | Aminoalkylphosphonates and related compounds as Edg receptor agonists |
CA2483594C (en) | 2002-05-16 | 2011-02-15 | Novartis Ag | Use of edg receptor binding agents in cancer |
JP2005533058A (ja) | 2002-06-17 | 2005-11-04 | メルク エンド カムパニー インコーポレーテッド | Edg受容体アゴニストとしての1−((5−アリール−1,2,4−オキサジアゾール−3−イル)ベンジル)アゼチジン−3−カルボキシラートおよび1−((5−アリール−1,2,4−オキサジアゾール−3−イル)ベンジル)ピロリジン−3−カルボキシラート |
EP1539674A1 (en) | 2002-09-13 | 2005-06-15 | Novartis AG | Amino-propanol derivatives |
JP4516430B2 (ja) | 2002-12-20 | 2010-08-04 | メルク・シャープ・エンド・ドーム・コーポレイション | 1−(アミノ)インダン並びに(1,2−ジヒドロ−3−アミノ)−ベンゾフラン、ベンゾチオフェン及びインドール |
TW200423930A (en) * | 2003-02-18 | 2004-11-16 | Hoffmann La Roche | Non-nucleoside reverse transcriptase inhibitors |
JP2006522825A (ja) | 2003-04-10 | 2006-10-05 | アムジェン インコーポレイテッド | ブラジキニンレセプター親和性を有する二環式化合物およびその薬学的組成物 |
JP2006522745A (ja) | 2003-04-11 | 2006-10-05 | ノボ ノルディスク アクティーゼルスカブ | 置換1,2,4−トリアゾールの薬学的使用 |
WO2004103279A2 (en) | 2003-05-15 | 2004-12-02 | Merck & Co., Inc. | 3-(2-amino-1-azacyclyl)-5-aryl-1,2,4-oxadiazoles as s1p receptor agonists |
US8286203B2 (en) * | 2003-12-19 | 2012-10-09 | At&T Intellectual Property I, L.P. | System and method for enhanced hot key delivery |
WO2005123677A1 (en) | 2004-06-16 | 2005-12-29 | Actelion Pharmaceuticals Ltd | 4-carbonyl substituted 1,1,2-trimethyl-1a,4,5,5a-tetrahydro-1h-4-aza-cyclopropa'a!pentalene derivatives as agonists for the g-protein-coupled receptor s1p1/edg1 and immunosuppressive agents |
CN1993333B (zh) | 2004-08-04 | 2012-08-01 | 大正制药株式会社 | 三唑衍生物 |
BRPI0500778B1 (pt) | 2005-02-03 | 2014-07-29 | Krupinite Corp Ltd | Beneficiamento químico de matéria-prima contendo Tântalo-Nióbio |
US20080161187A1 (en) | 2005-03-16 | 2008-07-03 | Basf Aktiengesellschaft | Biphenyl-N-(4-Pyridyl) Methylsulfonamides |
TW200736234A (en) | 2006-01-17 | 2007-10-01 | Astrazeneca Ab | Chemical compounds |
EP1988083B1 (en) | 2006-02-03 | 2014-04-02 | Taisho Pharmaceutical Co., Ltd. | Triazole derivative |
EP1988081B1 (en) | 2006-02-06 | 2012-10-17 | Taisho Pharmaceutical Co., Ltd | Binding inhibitor of sphingosine-1-phosphate |
US8097644B2 (en) | 2006-03-28 | 2012-01-17 | Allergan, Inc. | Indole compounds having sphingosine-1-phosphate (S1P) receptor antagonist |
CN101426770A (zh) | 2006-04-21 | 2009-05-06 | 阿斯利康(瑞典)有限公司 | 用作edg-1拮抗剂的咪唑衍生物 |
JP2009534365A (ja) | 2006-04-21 | 2009-09-24 | アストラゼネカ アクチボラグ | Adg受容体修飾物質として有用なスルホンアミド化合物 |
-
2007
- 2007-02-06 EP EP07713881A patent/EP1988081B1/en active Active
- 2007-02-06 PL PL07713881T patent/PL1988081T3/pl unknown
- 2007-02-06 WO PCT/JP2007/052052 patent/WO2007091570A1/ja active Application Filing
- 2007-02-06 ES ES07713881T patent/ES2393621T3/es active Active
- 2007-02-06 RU RU2008135995/04A patent/RU2395499C2/ru not_active IP Right Cessation
- 2007-02-06 JP JP2007557850A patent/JP5218737B2/ja not_active Expired - Fee Related
- 2007-02-06 US US12/278,477 patent/US7994204B2/en not_active Expired - Fee Related
- 2007-02-06 CN CN2007800124799A patent/CN101415687B/zh not_active Expired - Fee Related
-
2009
- 2009-09-30 HK HK09109077.8A patent/HK1131127A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US7994204B2 (en) | 2011-08-09 |
CN101415687A (zh) | 2009-04-22 |
US20090182144A1 (en) | 2009-07-16 |
EP1988081A1 (en) | 2008-11-05 |
CN101415687B (zh) | 2012-02-08 |
HK1131127A1 (en) | 2010-01-15 |
RU2395499C2 (ru) | 2010-07-27 |
EP1988081A4 (en) | 2010-12-22 |
JPWO2007091570A1 (ja) | 2009-07-02 |
RU2008135995A (ru) | 2010-03-20 |
JP5218737B2 (ja) | 2013-06-26 |
ES2393621T3 (es) | 2012-12-26 |
EP1988081B1 (en) | 2012-10-17 |
WO2007091570A1 (ja) | 2007-08-16 |
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