PL1966217T3 - Nowe, acykliczne podstawione pochodne furopirymidyny i ich zastosowanie do leczenia schorzeń sercowonaczyniowych - Google Patents
Nowe, acykliczne podstawione pochodne furopirymidyny i ich zastosowanie do leczenia schorzeń sercowonaczyniowychInfo
- Publication number
- PL1966217T3 PL1966217T3 PL06829427T PL06829427T PL1966217T3 PL 1966217 T3 PL1966217 T3 PL 1966217T3 PL 06829427 T PL06829427 T PL 06829427T PL 06829427 T PL06829427 T PL 06829427T PL 1966217 T3 PL1966217 T3 PL 1966217T3
- Authority
- PL
- Poland
- Prior art keywords
- novel
- cardiovascular diseases
- treating cardiovascular
- acyclic substituted
- furopyrimidine derivatives
- Prior art date
Links
- 208000024172 Cardiovascular disease Diseases 0.000 title 1
- 125000002015 acyclic group Chemical group 0.000 title 1
- JUQAECQBUNODQP-UHFFFAOYSA-N furo[3,2-d]pyrimidine Chemical class C1=NC=C2OC=CC2=N1 JUQAECQBUNODQP-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102005061170A DE102005061170A1 (de) | 2005-12-21 | 2005-12-21 | Neue, acyclisch substituierte Furopyrimidin-Derivate und ihre Verwendung |
| EP06829427.1A EP1966217B1 (de) | 2005-12-21 | 2006-12-08 | Neue, acyclisch substituierte furopyrimidin-derivate und ihre verwendung zur behandlung von kardiovaskulären erkrankungen |
| PCT/EP2006/011826 WO2007079862A1 (de) | 2005-12-21 | 2006-12-08 | Neue, acyclisch substituierte furopyrimidin-derivate und ihre verwendung zur behandlung von kardiovaskulären erkrankungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1966217T3 true PL1966217T3 (pl) | 2013-09-30 |
Family
ID=37876878
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL06829427T PL1966217T3 (pl) | 2005-12-21 | 2006-12-08 | Nowe, acykliczne podstawione pochodne furopirymidyny i ich zastosowanie do leczenia schorzeń sercowonaczyniowych |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US8183246B2 (pl) |
| EP (1) | EP1966217B1 (pl) |
| JP (1) | JP5254032B2 (pl) |
| KR (1) | KR101429777B1 (pl) |
| CN (1) | CN101384603B (pl) |
| AR (1) | AR058108A1 (pl) |
| AU (1) | AU2006334856B2 (pl) |
| BR (1) | BRPI0620317A2 (pl) |
| CA (1) | CA2633701C (pl) |
| CR (1) | CR10092A (pl) |
| DE (1) | DE102005061170A1 (pl) |
| DK (1) | DK1966217T3 (pl) |
| DO (1) | DOP2006000280A (pl) |
| EC (1) | ECSP088569A (pl) |
| ES (1) | ES2418855T3 (pl) |
| GT (1) | GT200800117A (pl) |
| IL (1) | IL192062A0 (pl) |
| MA (1) | MA30039B1 (pl) |
| NO (1) | NO20082986L (pl) |
| NZ (1) | NZ569214A (pl) |
| PE (1) | PE20071168A1 (pl) |
| PL (1) | PL1966217T3 (pl) |
| PT (1) | PT1966217E (pl) |
| RU (1) | RU2454419C2 (pl) |
| SV (1) | SV2009002953A (pl) |
| TN (1) | TNSN08279A1 (pl) |
| TW (1) | TWI405764B (pl) |
| UA (1) | UA94080C2 (pl) |
| UY (1) | UY30046A1 (pl) |
| WO (1) | WO2007079862A1 (pl) |
| ZA (1) | ZA200805385B (pl) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102007019691A1 (de) * | 2007-04-26 | 2008-10-30 | Bayer Healthcare Ag | Verwendung von acyclisch substituierten Furopyrimidin-Derivaten zur Behandlung der pulmonalen arteriellen Hypertonie |
| DE102007027799A1 (de) * | 2007-06-16 | 2008-12-18 | Bayer Healthcare Ag | Substituierte Furopyrimidine und ihre Verwendung |
| DE102007051762A1 (de) | 2007-10-30 | 2009-05-07 | Bayer Healthcare Ag | Substituierte Pyrrolotriazine und ihre Verwendung |
| DE102007054786A1 (de) | 2007-11-16 | 2009-05-20 | Bayer Healthcare Ag | Trisubstituierte Furopyrimidine und ihre Verwendung |
| US9440987B2 (en) | 2012-05-10 | 2016-09-13 | Takeda Pharmaceutical Company Limited | Aromatic ring compound |
| EP2848622A4 (en) | 2012-05-10 | 2015-11-04 | Takeda Pharmaceutical | Aromatic ring compound |
| KR102590848B1 (ko) | 2016-12-28 | 2023-10-19 | 다트 뉴로사이언스, 엘엘씨 | Pde2 억제제로서 치환된 피라졸로피리미디논 화합물 |
| ES2902365T3 (es) | 2017-11-27 | 2022-03-28 | Dart Neuroscience Llc | Compuestos de furanopirimidina sustituidos como inhibidores de PDE1 |
| CN114126620B (zh) * | 2019-05-13 | 2024-12-31 | 传达治疗有限公司 | Fgfr抑制剂和其使用方法 |
| KR102094337B1 (ko) | 2019-10-01 | 2020-03-27 | 안문호 | 금속이물질 제거장치 |
| WO2022109577A1 (en) | 2020-11-18 | 2022-05-27 | Relay Therapeutics, Inc. | Fgfr inhibitors and methods of making and using the same |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3577420A (en) | 1968-01-05 | 1971-05-04 | Pfizer | Certain 4-aminofuro(2,3-d)pyrimidines |
| WO2000005234A1 (en) | 1998-07-22 | 2000-02-03 | Suntory Limited | NF-λB INHIBITORS CONTAINING INDAN DERIVATIVES AS THE ACTIVE INGREDIENT |
| HK1045306A1 (zh) | 1999-06-03 | 2002-11-22 | Abbott Laboratories | 抑制细胞黏附的抗炎化合物 |
| JP4660045B2 (ja) | 1999-09-17 | 2011-03-30 | 松森 昭 | ＮＦ−κＢ阻害剤を有効成分とする心筋炎、拡張型心筋症および心不全の予防または治療薬 |
| ES2259707T3 (es) | 2001-05-14 | 2006-10-16 | Novartis Ag | Oxazolo y furopirimidinas y su uso en medicamentos contra tumores. |
| DE10141212A1 (de) * | 2001-08-22 | 2003-03-06 | Bayer Ag | Neue 4-Aminofuropyrimidine und ihre Verwendung |
| JP2005508904A (ja) | 2001-09-11 | 2005-04-07 | スミスクライン ビーチャム コーポレーション | 血管新生阻害剤としてのフロ−及びチエノピリミジン誘導体 |
| DE10148883A1 (de) * | 2001-10-04 | 2003-04-10 | Merck Patent Gmbh | Pyrimidinderivate |
| US20030225098A1 (en) * | 2002-03-21 | 2003-12-04 | Hirst Gavin C. | Kinase inhibitors |
| KR20050091462A (ko) | 2004-03-12 | 2005-09-15 | 한국과학기술연구원 | 푸로피리미딘 화합물 및 이를 포함하는 ｄｄｒ2 티로신키나아제 활성 저해제 |
| WO2005121149A1 (en) | 2004-06-10 | 2005-12-22 | Xention Discovery Limited | Furanopyrimidine compounds effective as potassium channel inhibitors |
| JP2008505084A (ja) * | 2004-06-29 | 2008-02-21 | アムゲン インコーポレイティッド | フラノピリミジン |
-
2005
- 2005-12-21 DE DE102005061170A patent/DE102005061170A1/de not_active Withdrawn
-
2006
- 2006-12-08 UA UAA200809519A patent/UA94080C2/ru unknown
- 2006-12-08 CN CN2006800532242A patent/CN101384603B/zh not_active Expired - Fee Related
- 2006-12-08 JP JP2008546193A patent/JP5254032B2/ja not_active Expired - Fee Related
- 2006-12-08 ES ES06829427T patent/ES2418855T3/es active Active
- 2006-12-08 RU RU2008129363/04A patent/RU2454419C2/ru not_active IP Right Cessation
- 2006-12-08 NZ NZ569214A patent/NZ569214A/en not_active IP Right Cessation
- 2006-12-08 KR KR1020087017526A patent/KR101429777B1/ko not_active Expired - Fee Related
- 2006-12-08 PL PL06829427T patent/PL1966217T3/pl unknown
- 2006-12-08 US US12/086,783 patent/US8183246B2/en not_active Expired - Fee Related
- 2006-12-08 BR BRPI0620317-5A patent/BRPI0620317A2/pt not_active IP Right Cessation
- 2006-12-08 AU AU2006334856A patent/AU2006334856B2/en not_active Ceased
- 2006-12-08 CA CA2633701A patent/CA2633701C/en not_active Expired - Fee Related
- 2006-12-08 EP EP06829427.1A patent/EP1966217B1/de not_active Not-in-force
- 2006-12-08 DK DK06829427.1T patent/DK1966217T3/da active
- 2006-12-08 WO PCT/EP2006/011826 patent/WO2007079862A1/de not_active Ceased
- 2006-12-08 PT PT68294271T patent/PT1966217E/pt unknown
- 2006-12-14 DO DO2006000280A patent/DOP2006000280A/es unknown
- 2006-12-18 AR ARP060105587A patent/AR058108A1/es not_active Application Discontinuation
- 2006-12-20 TW TW095147761A patent/TWI405764B/zh not_active IP Right Cessation
- 2006-12-20 PE PE2006001653A patent/PE20071168A1/es not_active Application Discontinuation
- 2006-12-20 UY UY30046A patent/UY30046A1/es not_active Application Discontinuation
-
2008
- 2008-06-11 IL IL192062A patent/IL192062A0/en unknown
- 2008-06-11 MA MA31016A patent/MA30039B1/fr unknown
- 2008-06-19 GT GT200800117A patent/GT200800117A/es unknown
- 2008-06-19 SV SV2008002953A patent/SV2009002953A/es not_active Application Discontinuation
- 2008-06-20 ZA ZA200805385A patent/ZA200805385B/xx unknown
- 2008-06-20 CR CR10092A patent/CR10092A/es not_active Application Discontinuation
- 2008-06-20 EC EC2008008569A patent/ECSP088569A/es unknown
- 2008-06-20 TN TNP2008000279A patent/TNSN08279A1/en unknown
- 2008-07-02 NO NO20082986A patent/NO20082986L/no not_active Application Discontinuation
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