PL1937805T3 - Sposób otrzymywania kwasu arachidonowego i/lub kwasu eikozapentaenowego - Google Patents

Sposób otrzymywania kwasu arachidonowego i/lub kwasu eikozapentaenowego

Info

Publication number
PL1937805T3
PL1937805T3 PL06841262T PL06841262T PL1937805T3 PL 1937805 T3 PL1937805 T3 PL 1937805T3 PL 06841262 T PL06841262 T PL 06841262T PL 06841262 T PL06841262 T PL 06841262T PL 1937805 T3 PL1937805 T3 PL 1937805T3
Authority
PL
Poland
Prior art keywords
desaturase
acid
production
elongase
expression
Prior art date
Application number
PL06841262T
Other languages
English (en)
Inventor
Johnathan A Napier
Olga Sayanova
Original Assignee
Basf Plant Science Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Plant Science Gmbh filed Critical Basf Plant Science Gmbh
Publication of PL1937805T3 publication Critical patent/PL1937805T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • C12N5/12Fused cells, e.g. hybridomas
    • C12N5/14Plant cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083Miscellaneous (1.14.99)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Botany (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
PL06841262T 2005-10-13 2006-10-10 Sposób otrzymywania kwasu arachidonowego i/lub kwasu eikozapentaenowego PL1937805T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0520843A GB2431158A (en) 2005-10-13 2005-10-13 Process for the production of arachidonic and/or eicosapentaenoic acid
EP06841262A EP1937805B1 (en) 2005-10-13 2006-10-10 Process for the production of arachidonic acid and/or eicosapentaenoic acid
PCT/EP2006/067223 WO2007042510A2 (en) 2005-10-13 2006-10-10 Process for the production of arachidonic acid and/or eicosapentaenoic acid

Publications (1)

Publication Number Publication Date
PL1937805T3 true PL1937805T3 (pl) 2012-07-31

Family

ID=35451694

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06841262T PL1937805T3 (pl) 2005-10-13 2006-10-10 Sposób otrzymywania kwasu arachidonowego i/lub kwasu eikozapentaenowego

Country Status (9)

Country Link
US (3) US8017839B2 (pl)
EP (2) EP1937805B1 (pl)
AT (1) ATE546519T1 (pl)
AU (1) AU2006301280C1 (pl)
CA (2) CA3021294C (pl)
ES (1) ES2380052T3 (pl)
GB (1) GB2431158A (pl)
PL (1) PL1937805T3 (pl)
WO (1) WO2007042510A2 (pl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0913897A2 (pt) * 2008-06-27 2016-11-01 Centre Nat Rech Scient células recombinantes e plantas de ácidos graxos de cadeias muito longas (agcml)
US8137714B2 (en) 2008-07-25 2012-03-20 Mary Kay Inc. Compositions comprising docynia delavajy extract and/or Elaeagnus lancelotus extract
BRPI0913818A2 (pt) * 2008-10-03 2017-03-28 Agrisoma Biosciences Inc método de produção de plantas transgênicas, planta transgênica e método de produção de óleo
CN107858204B (zh) 2008-11-18 2021-10-29 联邦科学技术研究组织 产生ω-3脂肪酸的酶和方法
EP2821492A3 (en) 2009-05-13 2015-04-08 BASF Plant Science Company GmbH Acyltransferases and uses thereof in fatty acid production
CA2763107A1 (en) 2009-06-08 2010-12-16 Basf Plant Science Company Gmbh Novel fatty acid elongation components and uses thereof
DE112010002967T5 (de) 2009-07-17 2012-10-11 Basf Plant Science Company Gmbh Neue Fettsäuredesaturasen und -elongasen und Anwendungen davon
CN112011566B (zh) 2009-08-31 2023-12-05 巴斯夫植物科学有限公司 用于在植物中增强种子特异性基因表达而促进增强的多不饱和脂肪酸合成的调节性核酸分子
CA2781559C (en) 2009-11-24 2018-09-04 Basf Plant Science Company Gmbh Novel fatty acid elongase and uses thereof
US9388436B2 (en) 2009-11-24 2016-07-12 Basf Plant Science Company Gmbh Fatty acid desaturase and uses thereof
NO2585603T3 (pl) 2010-06-25 2018-05-19
EP2695936B1 (en) 2010-10-21 2016-04-20 BASF Plant Science Company GmbH Novel fatty acid desaturases and uses thereof
NZ631702A (en) 2012-06-15 2017-01-27 Grains Res & Dev Corp Production of long chain polyunsaturated fatty acids in plant cells
WO2014020533A2 (en) 2012-08-03 2014-02-06 Basf Plant Science Company Gmbh Novel enzymes, enzyme components and uses thereof
EP3795686A3 (en) 2013-07-05 2021-06-23 Basf Plant Science Company GmbH Gene expression or activity enhancing elements
CA3241340A1 (en) 2013-12-18 2015-06-25 Grains Research And Development Corporation Lipid comprising long chain polyunsaturated fatty acids
US10045540B2 (en) 2014-04-01 2018-08-14 Fayetteville State University Pest control composition
CA2953008C (en) 2014-06-27 2024-03-19 Nuseed Pty Ltd Lipid comprising docosapentaenoic acid
US10513718B2 (en) * 2017-06-06 2019-12-24 City University Of Hong Kong Method of producing polyunsaturated fatty acid
CN113842345B (zh) * 2021-10-15 2023-08-11 长沙中战茶油集团有限公司 一种冻干粉的制备方法及冻干粉

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5504200A (en) 1983-04-15 1996-04-02 Mycogen Plant Science, Inc. Plant gene expression
US5420034A (en) 1986-07-31 1995-05-30 Calgene, Inc. Seed-specific transcriptional regulation
DK162399C (da) 1986-01-28 1992-03-23 Danisco Fremgangsmaade til ekspression af gener i baelgplanteceller, dna-fragment, rekombineret dna-fragment samt plasmid til brug ved udoevelsen af fremgangsmaaden
US5614395A (en) 1988-03-08 1997-03-25 Ciba-Geigy Corporation Chemically regulatable and anti-pathogenic DNA sequences and uses thereof
NZ228320A (en) 1988-03-29 1991-06-25 Du Pont Nucleic acid promoter fragments of the promoter region homologous to the em gene of wheat, dna constructs therefrom and plants thereof
CA1341467C (en) 1988-07-29 2004-12-07 John C. Rogers Producing commercially valuable polypeptides with genetically transformed endosperm tissue
KR920701453A (ko) 1989-03-17 1992-08-11 미리엄 디. 멕코나헤이 유전자발현의 외부조절
EP0472722B1 (en) 1990-03-16 2003-05-21 Calgene LLC Dnas encoding plant desaturases and their uses
JPH04506155A (ja) 1990-03-16 1992-10-29 カルジーン,インコーポレイティド 初期種子形成において優先的に発現される新規配列およびそれに関連する方法
US5614393A (en) 1991-10-10 1997-03-25 Rhone-Poulenc Agrochimie Production of γ-linolenic acid by a Δ6-desaturase
PH31293A (en) 1991-10-10 1998-07-06 Rhone Poulenc Agrochimie Production of y-linolenic acid by a delta6-desaturage.
JPH07501701A (ja) 1991-12-04 1995-02-23 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 植物由来の脂肪酸不飽和化酵素遺伝子
CA2084348A1 (en) 1991-12-31 1993-07-01 David F. Hildebrand Fatty acid alteration by a d9 desaturase in transgenic plant tissue
DE4208050A1 (de) 1992-03-13 1993-09-23 Bayer Ag Azolylmethyl-fluorcyclopropyl-derivate
CA2092069A1 (en) 1992-03-27 1993-09-28 Asako Iida An expression plasmid for seeds
DE69331055T2 (de) 1992-04-13 2002-06-20 Syngenta Ltd., Haselmere Dna-konstruktionen und diese enthaltende pflanzen
JPH0662870A (ja) 1992-08-18 1994-03-08 Mitsui Giyousai Shokubutsu Bio Kenkyusho:Kk 大豆ホスホエノールピルビン酸カルボキシラーゼ遺伝子のプロモーター領域及び5’非翻訳領域
JP3818540B2 (ja) 1992-11-17 2006-09-06 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 植物由来のミクロソームデルタ−12脂肪酸デサチュラーゼおよび関連酵素の遺伝子
JPH08506490A (ja) 1993-02-05 1996-07-16 モンサント・カンパニー 植物中の改変リノレン酸及びリノール酸含量
GB9324707D0 (en) 1993-12-02 1994-01-19 Olsen Odd Arne Promoter
PT733059E (pt) 1993-12-09 2001-03-30 Univ Jefferson Compostos e metodos para mutacoes dirigidas ao local em celulas eucarioticas
WO1995018222A1 (fr) 1993-12-28 1995-07-06 Kirin Beer Kabushiki Kaisha Gene pour acide gras-desaturase, vecteur contenant ledit gene, vegetal contenant ledit gene lui ayant ete transfere, et procede pour creer ledit vegetal
GB9403512D0 (en) 1994-02-24 1994-04-13 Olsen Odd Arne Promoter
US6310194B1 (en) 1994-09-26 2001-10-30 Carnegie Institution Of Washington Plant fatty acid hydroxylases
US5689040A (en) 1995-02-23 1997-11-18 The Regents Of The University Of California Plant promoter sequences useful for gene expression in seeds and seedlings
AU717055B2 (en) 1995-07-05 2000-03-16 Sapporo Breweries Limited Tissue-specific promoter
ATE520302T1 (de) 1995-12-14 2011-09-15 Cargill Inc Pflanzen mit mutierten sequenzen, welche einen veränderten fettsäuregehalt vermitteln
EP0794250A1 (en) 1996-03-04 1997-09-10 Soremartec S.A. Isolation and sequencing of the hazel FAd2-N gene
US5981841A (en) 1996-08-30 1999-11-09 Monsanto Company Early seed 5' regulatory sequence
US5977436A (en) 1997-04-09 1999-11-02 Rhone Poulenc Agrochimie Oleosin 5' regulatory region for the modification of plant seed lipid composition
US5972664A (en) 1997-04-11 1999-10-26 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
DE69830587T2 (de) 1997-04-11 2006-05-24 Calgene Llc, Davis Verfahren und zusammensetzungen für die synthese von langkettigen, mehrfach ungesättigten fettsäuren in pflanzen.
AR013633A1 (es) 1997-04-11 2001-01-10 Calgene Llc METODO PARA LA ALTERACIoN DE LA COMPOSICIoN DE ÁCIDOS GRASOS DE CADENA MEDIA EN SEMILLAS VEGETALES QUE EXPRESAN UNA TIOESTERASA QUE PREFIERE CADENA MEDIA VEGETAL HETERoLOGA.
US5968809A (en) 1997-04-11 1999-10-19 Abbot Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
WO1999016890A2 (en) 1997-09-30 1999-04-08 The Regents Of The University Of California Production of proteins in plant seeds
GB9724783D0 (en) 1997-11-24 1998-01-21 Inst Arable Crops Research Novel polypeptides
BR9814434A (pt) 1997-12-23 2001-10-23 Univ Bristol Desaturase
WO1999064616A2 (en) 1998-06-12 1999-12-16 Abbott Laboratories Polyunsaturated fatty acids in plants
US6403349B1 (en) * 1998-09-02 2002-06-11 Abbott Laboratories Elongase gene and uses thereof
US6555732B1 (en) 1998-09-14 2003-04-29 Pioneer Hi-Bred International, Inc. Rac-like genes and methods of use
EP1121150A4 (en) 1998-10-09 2003-06-04 Merck & Co Inc DELAT 6 FATTY ACID DESATURASE
ATE353952T1 (de) 1998-12-07 2007-03-15 Univ Washington Desaturasen und verfahren ihrer anwendung zur synthese von mehrfach ungesättigten fettsäuren
CA2510462A1 (en) * 2002-12-19 2004-07-08 University Of Bristol Method for producing polyunsaturated fatty acids in a transgenic plant or microorganism comprising an introduced delta-9-elongase and a delta-8-desaturase
CA3037924A1 (en) 2003-08-01 2005-02-10 Basf Plant Science Gmbh Method for the production of polyunsaturated fatty acids in transgenic organisms
US7504259B2 (en) * 2003-11-12 2009-03-17 E. I. Du Pont De Nemours And Company Δ12 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous yeast
JP4916886B2 (ja) * 2003-11-12 2012-04-18 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 油性植物および酵母中の多価不飽和脂肪酸レベルを変更するのに適したδ15デサチュラーゼ

Also Published As

Publication number Publication date
WO2007042510A3 (en) 2007-08-02
ES2380052T3 (es) 2012-05-08
AU2006301280A1 (en) 2007-04-19
US20120017332A1 (en) 2012-01-19
EP2450434A3 (en) 2012-08-08
EP1937805A2 (en) 2008-07-02
EP2450434B1 (en) 2016-01-06
US20120011618A1 (en) 2012-01-12
EP1937805B1 (en) 2012-02-22
CA3021294C (en) 2021-09-21
CA3021294A1 (en) 2007-04-19
GB2431158A (en) 2007-04-18
ATE546519T1 (de) 2012-03-15
US20100043103A1 (en) 2010-02-18
GB0520843D0 (en) 2005-11-23
US8017839B2 (en) 2011-09-13
CA2621214A1 (en) 2007-04-19
EP2450434A2 (en) 2012-05-09
WO2007042510A2 (en) 2007-04-19
US8258371B2 (en) 2012-09-04
AU2006301280C1 (en) 2012-08-30
CA2621214C (en) 2018-12-04
US8273958B2 (en) 2012-09-25
AU2006301280B2 (en) 2012-03-15

Similar Documents

Publication Publication Date Title
GB0520843D0 (en) Process for the production of arachidonic acid and / or eicosapentaenoic acid
WO2004057001A3 (en) Method for the production of polyunsaturated fatty acids
DE69937050D1 (de) Polyungesättigte fettsäuren in pflanzen
WO2005083093A3 (de) Verfahren zur herstellung mehrfach ungesättigter fettsäuren in transgenen pflanzen
WO1999064616A3 (en) Polyunsaturated fatty acids in plants
MXPA06009572A (es) Metodo para la produccion de acidos grasos poliinsaturados en plantas transgenicas.
EP1598422A3 (en) Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants
MXPA03000750A (es) Genes de elongasa y usos de los mismos.
WO2005083053A3 (de) Verfahren zur herstellung von ungesättigten omega-3-fettsäuren in transgenen organismen
NO20073045L (no) Fremgangsmate for fremstilling av polyumettede fettsyrer i transgene organismer
WO2006100241A3 (de) Verfahren zur herstellung von mehrfach ungesättigten c20- und c22-fettsäuren mit mindestens vier doppelbindungen in transgenen pflanzen
WO2004071467A3 (en) Production of very long chain polyunsaturated fatty acids in oilseed plants
MY165098A (en) Production of dha and other lc-pufas in plants
NO20043890L (no) Delta 6-saturaser fra Primulaceae-uttrykkende planter og PUFA-inneholdende oljer
WO2010023202A3 (en) Nucleic acids encoding desaturases and modified plant oil
WO2007136671A3 (en) Delta5 desaturase and its use in making polyunsaturated fatty acids
EP2166090A3 (de) Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen Organismen
WO2007136646A3 (en) Delta5 desaturase and its use in making polyunsaturated fatty acids
NO20043592L (no) Nytt elongasegen og fremgangsmate for fremstilling av flerumettede fettsyrer
WO2007017419A3 (de) Verfahren zur herstellung von arachidonsäure und/oder eicosapentaensäure in transgenen nutzpflanzen
DK2010648T3 (da) Delta-17-desaturaser og anvendelse heraf i fremstillingen af flerumættede fedtsyrer
UA102059C2 (uk) Дельта-8 десатураза та її застосування для одержання поліненасичених жирних кислот
WO2007051577A3 (de) VERFAHREN ZUR HERSTELLUNG VON γ-LINOLENSÄURE UND/ ODER STEARIDONSÄURE IN TRANSGENEN BRASSICACEAE UND LINACEAE
ATE538198T1 (de) Elongasegene und deren verwendungen
ATE486939T1 (de) Aus der marchantiales-pflanze stammendes gen für ungesättigte-fettsäure-synthase und dessen nutzung