DK2010648T3 - Delta-17-desaturaser og anvendelse heraf i fremstillingen af flerumættede fedtsyrer - Google Patents
Delta-17-desaturaser og anvendelse heraf i fremstillingen af flerumættede fedtsyrerInfo
- Publication number
- DK2010648T3 DK2010648T3 DK07775772.2T DK07775772T DK2010648T3 DK 2010648 T3 DK2010648 T3 DK 2010648T3 DK 07775772 T DK07775772 T DK 07775772T DK 2010648 T3 DK2010648 T3 DK 2010648T3
- Authority
- DK
- Denmark
- Prior art keywords
- desaturases
- fatty acids
- delta17
- polyunsaturated fatty
- delta
- Prior art date
Links
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 title abstract 2
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 abstract 2
- 235000020673 eicosapentaenoic acid Nutrition 0.000 abstract 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 abstract 1
- 235000021342 arachidonic acid Nutrition 0.000 abstract 1
- 229940114079 arachidonic acid Drugs 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 229960005135 eicosapentaenoic acid Drugs 0.000 abstract 1
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 235000020978 long-chain polyunsaturated fatty acids Nutrition 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 1
- 235000020660 omega-3 fatty acid Nutrition 0.000 abstract 1
- 235000020665 omega-6 fatty acid Nutrition 0.000 abstract 1
- 229940033080 omega-6 fatty acid Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6432—Eicosapentaenoic acids [EPA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0083—Miscellaneous (1.14.99)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0083—Miscellaneous (1.14.99)
- C12N9/0087—Steroid 21-monooxygenase (1.14.99.10)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Nutrition Science (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79357506P | 2006-04-20 | 2006-04-20 | |
| PCT/US2007/009572 WO2007123999A2 (en) | 2006-04-20 | 2007-04-19 | Δ17 desaturases and their use in making polyunsaturated fatty acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2010648T3 true DK2010648T3 (da) | 2012-05-21 |
Family
ID=38625589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07775772.2T DK2010648T3 (da) | 2006-04-20 | 2007-04-19 | Delta-17-desaturaser og anvendelse heraf i fremstillingen af flerumættede fedtsyrer |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7465793B2 (da) |
| EP (1) | EP2010648B1 (da) |
| JP (1) | JP2009534032A (da) |
| CN (1) | CN101646766B (da) |
| AT (1) | ATE542892T1 (da) |
| AU (1) | AU2007240741B2 (da) |
| DK (1) | DK2010648T3 (da) |
| MX (1) | MX2008013306A (da) |
| WO (1) | WO2007123999A2 (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2061879A2 (en) * | 2006-08-24 | 2009-05-27 | BASF Plant Science GmbH | Isolation and characterization of a novel pythium omega 3 desaturase with specificity to all omega 6 fatty acids longer than 18 carbon chains |
| US7556949B2 (en) | 2006-10-30 | 2009-07-07 | E.I. Du Pont De Nemours And Company | Δ17 desaturase and its use in making polyunsaturated fatty acids |
| US7709239B2 (en) * | 2006-12-07 | 2010-05-04 | E.I. Du Pont De Nemours And Company | Mutant Δ8 desaturase genes engineered by targeted mutagenesis and their use in making polyunsaturated fatty acids |
| US7794701B2 (en) * | 2007-04-16 | 2010-09-14 | E.I. Du Pont De Nemours And Company | Δ-9 elongases and their use in making polyunsaturated fatty acids |
| CN102186876B (zh) * | 2008-10-14 | 2014-06-11 | 孟山都技术公司 | 来自半片藻属的脂肪酸脱饱和酶的利用 |
| EP2669380B1 (en) * | 2008-12-12 | 2017-09-27 | BASF Plant Science GmbH | Desaturases and process for the production of polyunsaturated fatty acids in transgenic organisms |
| WO2012027676A1 (en) * | 2010-08-26 | 2012-03-01 | E. I. Du Pont De Nemours And Company | Mutant delta-9 elongases and their use in making polyunsaturated fatty acids |
| JPWO2015029966A1 (ja) | 2013-08-27 | 2017-03-02 | 国立大学法人京都大学 | ω３不飽和脂肪酸酵素およびエイコサペンタエン酸の製造方法 |
| JP6026709B1 (ja) * | 2014-12-25 | 2016-11-16 | 国立大学法人京都大学 | 新規ω３不飽和脂肪酸酵素およびエイコサペンタエン酸の製造方法 |
| US10533232B2 (en) * | 2015-12-09 | 2020-01-14 | Jiangnan University | Parasitic phytophthora-derived omega-3 fatty acid desaturase for synthesizing polyunsaturated fatty acids, carrier containing fatty acid desaturase, recombinant microorganisms, and application thereof |
| CN105368851B (zh) * | 2015-12-09 | 2019-05-07 | 江南大学 | 一种来源于寄生疫霉的ω-3脱饱和酶、含所述脱饱和酶的载体、重组微生物及其应用 |
| CN106916796B (zh) * | 2015-12-28 | 2021-06-29 | 丰益(上海)生物技术研发中心有限公司 | 裂殖壶菌delta-12脂肪酸脱饱和酶相关序列及其应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US7008664B1 (en) * | 1998-06-11 | 2006-03-07 | E. I. Du Pont De Nemours And Company | Method for improving the carcass quality of an animal |
| US6635451B2 (en) | 2001-01-25 | 2003-10-21 | Abbott Laboratories | Desaturase genes and uses thereof |
| US7125672B2 (en) | 2003-05-07 | 2006-10-24 | E. I. Du Pont De Nemours And Company | Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts |
| US7238482B2 (en) | 2003-05-07 | 2007-07-03 | E. I. Du Pont De Nemours And Company | Production of polyunsaturated fatty acids in oleaginous yeasts |
| EP2166070B1 (de) | 2003-08-01 | 2015-09-16 | BASF Plant Science GmbH | Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen Organismen |
| WO2005047479A2 (en) | 2003-11-12 | 2005-05-26 | E.I. Dupont De Nemours And Company | Delta-15 desaturases suitable for altering levels of polyunsaturated fatty acids in oilseed plants and oleaginous yeast |
| CA2559360A1 (en) | 2004-02-27 | 2005-09-09 | Basf Plant Science Gmbh | Method for producing c18, c20 and c22 polyunsaturated fatty acids in transgenic plants |
| US7777098B2 (en) | 2004-02-27 | 2010-08-17 | Basf Plant Science Gmbh | Method for producing unsaturated ω-3-fatty acids in transgenic organisms |
| US7550286B2 (en) | 2004-11-04 | 2009-06-23 | E. I. Du Pont De Nemours And Company | Docosahexaenoic acid producing strains of Yarrowia lipolytica |
| US7192762B2 (en) | 2004-11-04 | 2007-03-20 | E. I. Du Pont De Nemours And Company | Mortierella alpina glycerol-3-phosphate o-acyltransferase for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms |
| US7189559B2 (en) | 2004-11-04 | 2007-03-13 | E. I. Du Pont De Nemours And Company | Mortierella alpina lysophosphatidic acid acyltransferase homolog for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms |
| DE102005013779A1 (de) | 2005-03-22 | 2006-09-28 | Basf Plant Science Gmbh | Verfahren zur Herstellung von mehrfach ungesättigten C20- und C22-Fettsäuren mit mindestens vier Doppelbindungen in transgenen Pflanzen |
-
2007
- 2007-04-18 US US11/787,772 patent/US7465793B2/en not_active Expired - Fee Related
- 2007-04-19 CN CN2007800139991A patent/CN101646766B/zh not_active Expired - Fee Related
- 2007-04-19 JP JP2009506580A patent/JP2009534032A/ja not_active Ceased
- 2007-04-19 WO PCT/US2007/009572 patent/WO2007123999A2/en not_active Ceased
- 2007-04-19 EP EP07775772A patent/EP2010648B1/en not_active Not-in-force
- 2007-04-19 DK DK07775772.2T patent/DK2010648T3/da active
- 2007-04-19 MX MX2008013306A patent/MX2008013306A/es not_active Application Discontinuation
- 2007-04-19 AT AT07775772T patent/ATE542892T1/de active
- 2007-04-19 AU AU2007240741A patent/AU2007240741B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP2010648A2 (en) | 2009-01-07 |
| CN101646766B (zh) | 2013-03-27 |
| JP2009534032A (ja) | 2009-09-24 |
| WO2007123999A2 (en) | 2007-11-01 |
| CN101646766A (zh) | 2010-02-10 |
| MX2008013306A (es) | 2008-10-27 |
| WO2007123999A3 (en) | 2008-04-24 |
| US7465793B2 (en) | 2008-12-16 |
| AU2007240741B2 (en) | 2013-01-31 |
| AU2007240741A1 (en) | 2007-11-01 |
| US20070249026A1 (en) | 2007-10-25 |
| ATE542892T1 (de) | 2012-02-15 |
| EP2010648B1 (en) | 2012-01-25 |
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