PL1888537T3 - Sposób otrzymywania 4-[(1,6-dihydro-6-okso-2-pirymidynylo)amino benzonitrylu - Google Patents
Sposób otrzymywania 4-[(1,6-dihydro-6-okso-2-pirymidynylo)amino benzonitryluInfo
- Publication number
- PL1888537T3 PL1888537T3 PL06755299T PL06755299T PL1888537T3 PL 1888537 T3 PL1888537 T3 PL 1888537T3 PL 06755299 T PL06755299 T PL 06755299T PL 06755299 T PL06755299 T PL 06755299T PL 1888537 T3 PL1888537 T3 PL 1888537T3
- Authority
- PL
- Poland
- Prior art keywords
- pyrimidinyl
- dihydro
- oxo
- preparing
- amino benzonitrile
- Prior art date
Links
- -1 1,6-dihydro-6-oxo-2-pyrimidinyl Chemical group 0.000 title 1
- HLCPWBZNUKCSBN-UHFFFAOYSA-N 2-aminobenzonitrile Chemical compound NC1=CC=CC=C1C#N HLCPWBZNUKCSBN-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05104531 | 2005-05-26 | ||
US68599305P | 2005-05-31 | 2005-05-31 | |
EP06755299.2A EP1888537B1 (en) | 2005-05-26 | 2006-05-24 | Process for preparing 4-[(1,6-dihydro-6-oxo-2-pyrimidinyl)amino benzonitrile |
PCT/EP2006/062606 WO2006125809A1 (en) | 2005-05-26 | 2006-05-24 | Process for preparing 4-[(1,6-dihydro-6-oxo-2-pyrimidinyl)amino benzonitrile |
Publications (1)
Publication Number | Publication Date |
---|---|
PL1888537T3 true PL1888537T3 (pl) | 2014-02-28 |
Family
ID=35822492
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL06755299T PL1888537T3 (pl) | 2005-05-26 | 2006-05-24 | Sposób otrzymywania 4-[(1,6-dihydro-6-okso-2-pirymidynylo)amino benzonitrylu |
Country Status (19)
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2007014881A (es) * | 2005-05-26 | 2008-02-15 | Tibotec Pharm Ltd | Procedimiento para preparar 4-(1,6-dihidro-6-oxo-2-pirimidinil) amino benzonitrilo. |
WO2012125993A1 (en) | 2011-03-17 | 2012-09-20 | Teva Pharmaceutical Industries Ltd. | Solid state forms of rilpivirine base, and rilipivirine salts |
ES2642383T3 (es) | 2012-03-13 | 2017-11-16 | Octapharma Ag | Procedimiento mejorado de producción de fibrinógeno y fibrinógeno producido por el mismo |
CN103058936B (zh) * | 2013-01-23 | 2016-01-06 | 宁波九胜创新医药科技有限公司 | 4-[(4-氯-2-嘧啶基)氨基]苯腈的制备方法 |
CN103193719B (zh) * | 2013-04-08 | 2015-07-22 | 宁波九胜创新医药科技有限公司 | 一种4-[(4-羟基-2-嘧啶基)氨基]苯腈的制备方法 |
CN114933567B (zh) * | 2022-04-29 | 2023-07-11 | 武汉工程大学 | 一种2-甲硫基-4-嘧啶酮的制备方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE63502B1 (en) | 1989-04-21 | 1995-05-03 | Zeneca Ltd | Aminopyrimidine derivatives useful for treating cardiovascular disorders |
DE3923979A1 (de) | 1989-07-20 | 1991-01-24 | Merck Patent Gmbh | Verfahren zur herstellung von aromatischen nitrilen |
RU2037483C1 (ru) * | 1989-07-20 | 1995-06-19 | Мерк Патент Гмбх | Способ получения замещенных ароматических нитрилов |
ATE232521T1 (de) | 1998-03-27 | 2003-02-15 | Janssen Pharmaceutica Nv | Hiv hemmende pyrimidin derivate |
AP1683A (en) * | 1998-11-10 | 2006-11-29 | Janssen Pharmaceutica Nv | HIV replication inhibiting pyrimidines. |
WO2001022938A1 (en) * | 1999-09-24 | 2001-04-05 | Janssen Pharmaceutica N.V. | Antiviral compositions |
JP4969010B2 (ja) * | 2000-05-08 | 2012-07-04 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Hiv複製阻害性ピリミジンのプロドラッグ |
JO3429B1 (ar) * | 2001-08-13 | 2019-10-20 | Janssen Pharmaceutica Nv | مشتقات برميدينات مثبطة فيروس الايدز |
WO2003037891A1 (en) * | 2001-11-01 | 2003-05-08 | Janssen Pharmaceutica N.V. | Heteroaryl amines as glycogen synthase kinase 3beta inhibitors (gsk3 inhibitors) |
AU2003266413B2 (en) * | 2002-08-09 | 2009-04-02 | Janssen Pharmaceutica N.V. | Processes for the preparation of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile |
ATE427303T1 (de) * | 2003-09-30 | 2009-04-15 | Janssen Pharmaceutica Nv | Benzoimidazolverbindungen |
MX2007014881A (es) * | 2005-05-26 | 2008-02-15 | Tibotec Pharm Ltd | Procedimiento para preparar 4-(1,6-dihidro-6-oxo-2-pirimidinil) amino benzonitrilo. |
-
2006
- 2006-05-24 MX MX2007014881A patent/MX2007014881A/es active IP Right Grant
- 2006-05-24 EP EP06755299.2A patent/EP1888537B1/en active Active
- 2006-05-24 HR HRP20131133TT patent/HRP20131133T1/hr unknown
- 2006-05-24 US US11/913,200 patent/US8101752B2/en active Active
- 2006-05-24 BR BRPI0611038A patent/BRPI0611038B8/pt active IP Right Grant
- 2006-05-24 WO PCT/EP2006/062606 patent/WO2006125809A1/en active Application Filing
- 2006-05-24 AU AU2006251163A patent/AU2006251163C1/en active Active
- 2006-05-24 PT PT67552992T patent/PT1888537E/pt unknown
- 2006-05-24 RU RU2007148968/04A patent/RU2458056C2/ru active
- 2006-05-24 IN IN4588DEN2014 patent/IN2014DN04588A/en unknown
- 2006-05-24 ES ES06755299.2T patent/ES2437202T3/es active Active
- 2006-05-24 ME MEP-2013-136A patent/ME01612B/me unknown
- 2006-05-24 CN CN2006800178794A patent/CN101248051B/zh active Active
- 2006-05-24 PL PL06755299T patent/PL1888537T3/pl unknown
- 2006-05-24 SI SI200631704T patent/SI1888537T1/sl unknown
- 2006-05-24 RS RS20130528A patent/RS53062B/en unknown
- 2006-05-24 JP JP2008512841A patent/JP5148483B2/ja active Active
- 2006-05-24 CA CA2609716A patent/CA2609716C/en active Active
- 2006-05-24 DK DK06755299.2T patent/DK1888537T3/da active
-
2011
- 2011-12-14 US US13/325,621 patent/US8618291B2/en active Active
-
2012
- 2012-10-17 JP JP2012229897A patent/JP5580385B2/ja active Active
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