PL1747269T3 - Rekombinowany enzym o zmienionej wrażliwości na sprzężenie zwrotne - Google Patents

Rekombinowany enzym o zmienionej wrażliwości na sprzężenie zwrotne

Info

Publication number
PL1747269T3
PL1747269T3 PL05742717T PL05742717T PL1747269T3 PL 1747269 T3 PL1747269 T3 PL 1747269T3 PL 05742717 T PL05742717 T PL 05742717T PL 05742717 T PL05742717 T PL 05742717T PL 1747269 T3 PL1747269 T3 PL 1747269T3
Authority
PL
Poland
Prior art keywords
recombinant enzyme
feedback sensitivity
altered feedback
altered
sensitivity
Prior art date
Application number
PL05742717T
Other languages
English (en)
Inventor
Gwénaëlle Bestel-Corre
Michel Chateau
Rainer Martin Figge
Céline Raynaud
Philippe Noel Paul Soucaille
Original Assignee
Evonik Degussa Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Degussa Gmbh filed Critical Evonik Degussa Gmbh
Publication of PL1747269T3 publication Critical patent/PL1747269T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL05742717T 2004-05-12 2005-05-12 Rekombinowany enzym o zmienionej wrażliwości na sprzężenie zwrotne PL1747269T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/IB2004/001901 WO2005111202A1 (en) 2004-05-12 2004-05-12 Recombinant enzyme with altered feedback sensitivity
EP05742717.1A EP1747269B1 (en) 2004-05-12 2005-05-12 Recombinant enzyme with altered feedback sensitivity
PCT/EP2005/052180 WO2005108561A2 (en) 2004-05-12 2005-05-12 Recombinant enzyme with altered feedback sensitivity

Publications (1)

Publication Number Publication Date
PL1747269T3 true PL1747269T3 (pl) 2015-08-31

Family

ID=34957660

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05742717T PL1747269T3 (pl) 2004-05-12 2005-05-12 Rekombinowany enzym o zmienionej wrażliwości na sprzężenie zwrotne

Country Status (8)

Country Link
US (1) US8795990B2 (pl)
EP (1) EP1747269B1 (pl)
JP (1) JP5164566B2 (pl)
CN (1) CN1954067B (pl)
ES (1) ES2535816T3 (pl)
MX (1) MXPA06013125A (pl)
PL (1) PL1747269T3 (pl)
WO (2) WO2005111202A1 (pl)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4110641B2 (ja) 1998-11-17 2008-07-02 味の素株式会社 発酵法によるl−メチオニンの製造法
WO2006082252A2 (en) * 2005-02-07 2006-08-10 Metabolic Explorer Method for the enzymatic production of alpha-ketobutyrate
BRPI0620880B1 (pt) * 2006-01-04 2018-10-09 Evonik Degussa Gmbh método para a produção de metionina, pelo cultivo de um microorganismo, e, microorganismo
KR100905381B1 (ko) * 2006-07-28 2009-06-30 씨제이제일제당 (주) L-메치오닌 전구체 생산 균주 및 상기 l-메치오닌전구체로부터의 l-메치오닌 및 유기산의 생산방법
CN101134948B (zh) 2006-08-31 2011-12-07 百瑞全球有限公司 S-腺苷甲硫氨酸合成酶突变体、编码该突变体的dna以及突变体的应用
EP2808382B1 (en) 2007-04-11 2016-03-16 CJ CheilJedang Corporation Compositions and methods of producing methionine
CN102703398B (zh) * 2007-04-11 2014-06-04 Cj第一制糖株式会社 组合物及甲硫氨酸的生产方法
CN103710319B (zh) * 2007-04-11 2015-10-07 Cj第一制糖株式会社 组合物及甲硫氨酸的生产方法
CA2687559A1 (en) * 2007-06-25 2009-04-02 Plant Bioscience Limited Enzymes involved in triterpene synthesis
WO2009043372A1 (en) 2007-10-02 2009-04-09 Metabolic Explorer Increasing methionine yield
US9005952B2 (en) 2008-04-04 2015-04-14 Cj Cheiljedang Corporation Microorganism producing L-methionine precursor and the method of producing L-methionine precursor using the microorganism
US7851180B2 (en) * 2008-04-04 2010-12-14 Cj Cheiljedang Corporation Microorganism producing L-methionine precursor and the method of producing L-methionine precursor using the microorganism
WO2010022763A1 (en) * 2008-08-25 2010-03-04 Metabolic Explorer Method for the preparation of 2-hydroxy-isobutyrate
JP5774493B2 (ja) 2008-12-31 2015-09-09 メタボリック エクスプローラー ジオールの生産方法
US8283152B2 (en) * 2009-08-28 2012-10-09 Cj Cheiljedang Corporation Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism
US8609396B2 (en) 2009-08-28 2013-12-17 Cj Cheiljedang Corporation Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism
FR2951195B1 (fr) 2009-10-14 2014-01-31 Roquette Freres Composition riche en methionine destinee a l'alimentation animale
WO2011065469A1 (ja) 2009-11-30 2011-06-03 味の素株式会社 L-システイン生産菌及びl-システインの製造法
WO2011073738A1 (en) 2009-12-14 2011-06-23 Metabolic Explorer Use of inducible promoters in the production of methionine
MX2012007718A (es) 2009-12-30 2012-07-25 Metabolic Explorer Sa Aumento de la produccion de metionina mediante la sobreexpresion de succinato deshidrogenasa.
WO2011080301A2 (en) 2009-12-30 2011-07-07 Metabolic Explorer Strains and method for the production of methionine
WO2012001003A1 (en) 2010-07-02 2012-01-05 Metabolic Explorer Method for the preparation of hydroxy acids
TWI500768B (zh) 2010-07-05 2015-09-21 Metabolic Explorer Sa 由蔗糖製備1,3-丙二醇之方法
WO2012014228A1 (en) 2010-07-28 2012-02-02 Abhishek Narain Singh A method to by-pass allosteric domain activity of an enzyme so as to alter its feedback or feed-forward inhibition or activation
BR112013006031A2 (pt) 2010-09-14 2016-06-07 Ajinomoto Kk bactéria,e, método para produzir um aminoácido contendo enxofre, uma substância relacionada ao mesmo, ou uma mnistura dos mesmos.
AR083468A1 (es) 2010-10-25 2013-02-27 Metabolic Explorer Sa Aumento de la disponibilidad de nadph para la produccion de metionina
MY173933A (en) 2010-12-21 2020-02-27 Cj Cheiljedang Corp Modified polypeptide having homoserine acetyltransferase activity and microorganism expressing the same
CN103429748B (zh) * 2010-12-30 2016-01-06 代谢探索者公司 甲硫氨酸羟基类似物(mha)的发酵产生
WO2012090021A1 (en) 2010-12-30 2012-07-05 Metabolic Explorer Recombinant microorganism for the fermentative production of methionine
JP2014087259A (ja) 2011-02-22 2014-05-15 Ajinomoto Co Inc L−システイン生産菌及びl−システインの製造法
JP6020443B2 (ja) 2011-04-01 2016-11-02 味の素株式会社 L−システインの製造法
US9234223B2 (en) 2011-04-01 2016-01-12 Ajinomoto Co., Inc. Method for producing L-cysteine
EP2540834A1 (en) 2011-06-29 2013-01-02 Metabolic Explorer Method for the preparation of 1,3-propanediol
WO2013053824A1 (en) 2011-10-11 2013-04-18 Metabolic Explorer New biosynthesis pathway for prenol in a recombinant microorganism
FR2983870B1 (fr) 2011-12-08 2015-07-17 Roquette Freres Composition en methionine destinee a l'alimentation animale
EP2647718A3 (en) 2012-04-06 2014-12-24 Metabolic Explorer Process for producing 5-aminopentanoate empolying a recombinant microorganism
JP2012196222A (ja) * 2012-06-11 2012-10-18 Metabolic Explorer 硫酸透過酵素の発現が増強された微生物を用いてメチオニンおよびその前駆体ホモセリンまたはスクシニルホモセリンを製造するための方法
US9506093B2 (en) 2012-06-18 2016-11-29 Metabolic Explorer Recombinant microorganism for the fermentative production of methionine
EP2898086B1 (en) 2012-09-19 2018-11-14 F.Hoffmann-La Roche Ag Methods and compositions for preventing norleucine misincorporation into proteins
WO2014049382A2 (en) 2012-09-26 2014-04-03 Metabolic Explorer Ethylenediamine fermentative production by a recombinant microorganism
MY185322A (en) 2013-05-13 2021-05-04 Ajinomoto Kk Method for producing l-amino acid
EP3039153B1 (en) 2013-08-30 2018-08-22 Evonik Degussa GmbH Microorganism for methionine production with improved methionine synthase activity and methionine efflux
CN104736707B (zh) 2013-10-21 2017-08-25 味之素株式会社 生产l‑氨基酸的方法
WO2015060391A1 (ja) 2013-10-23 2015-04-30 味の素株式会社 目的物質の製造法
CA2959563A1 (en) 2014-09-01 2016-03-10 Metabolic Explorer Method and microorganism for methionine production by fermentation with improved methionine efflux
CN105505894A (zh) * 2014-09-24 2016-04-20 中国科学院天津工业生物技术研究所 天冬氨酸激酶/高丝氨酸脱氢酶突变体及其应用
RU2017142360A (ru) * 2015-05-06 2019-06-06 Трелис, Инк. Композиции и способы для биологического получения метионина
EP3095868A1 (en) 2015-05-19 2016-11-23 Evonik Degussa GmbH Methionine production
US20180135085A1 (en) 2015-07-10 2018-05-17 Evonik Degussa Gmbh Amino acid production
PL3331998T3 (pl) 2015-08-07 2020-12-28 Evonik Operations Gmbh Wytwarzanie przez fermentację l-metioniny zależne od tiokarboksylanu białka
BR112018010747A8 (pt) 2015-11-27 2019-02-26 Evonik Degussa Gmbh método para a produção de l-metionina
WO2017118871A1 (en) 2016-01-08 2017-07-13 Metabolic Explorer Method to produce l-methionine by a fermentative production
CN105838740B (zh) * 2016-05-03 2020-11-06 湖北大学 一种茶树内生草螺菌制备纳米红色元素硒的方法
US10961499B2 (en) 2016-07-08 2021-03-30 Metabolic Explorer Method for the fermentative production of molecules of interest by microorganisms comprising genes coding sugar phosphotransferase system (PTS)
EP3296404A1 (en) 2016-09-15 2018-03-21 Evonik Degussa GmbH Modified microorganism for production of methionine
JP7066977B2 (ja) 2017-04-03 2022-05-16 味の素株式会社 L-アミノ酸の製造法
BR112021005543A2 (pt) 2018-09-28 2021-06-29 Ajinomoto Co., Inc. método para produzir l-metionina
EP3861109A1 (en) 2018-10-05 2021-08-11 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
CN112725251B (zh) * 2019-10-14 2022-07-22 江南大学 一种生产亚精胺的工程菌
CN114107243B (zh) * 2021-12-09 2023-04-07 江南大学 一种甲硫氨酸腺苷转移酶突变体
CN117535263A (zh) * 2022-11-11 2024-02-09 山东理工大学 一种基于297位点的s-腺苷蛋氨酸合成酶突变体及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4110641B2 (ja) * 1998-11-17 2008-07-02 味の素株式会社 発酵法によるl−メチオニンの製造法
JP4622111B2 (ja) * 2001-02-09 2011-02-02 味の素株式会社 L−システイン生産菌及びl−システインの製造法
DE10247437A1 (de) * 2002-10-11 2004-04-29 Consortium für elektrochemische Industrie GmbH Feedback-resistente Homoserin-Transsuccinylasen
DE10249642A1 (de) * 2002-10-24 2004-05-13 Consortium für elektrochemische Industrie GmbH Feedback-resistente Homoserin-Transsuccinylasen mit modifiziertem C-Terminus

Also Published As

Publication number Publication date
JP5164566B2 (ja) 2013-03-21
US20090029424A1 (en) 2009-01-29
CN1954067A (zh) 2007-04-25
MXPA06013125A (es) 2007-02-14
CN1954067B (zh) 2011-08-03
US8795990B2 (en) 2014-08-05
EP1747269A2 (en) 2007-01-31
WO2005111202A1 (en) 2005-11-24
JP2007536921A (ja) 2007-12-20
WO2005108561A2 (en) 2005-11-17
EP1747269B1 (en) 2015-03-25
ES2535816T3 (es) 2015-05-18
WO2005108561A3 (en) 2006-07-20

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