PL1687435T3 - Odporność na owady z użyciem hamowania ekspresji genów - Google Patents

Odporność na owady z użyciem hamowania ekspresji genów

Info

Publication number
PL1687435T3
PL1687435T3 PL04818796T PL04818796T PL1687435T3 PL 1687435 T3 PL1687435 T3 PL 1687435T3 PL 04818796 T PL04818796 T PL 04818796T PL 04818796 T PL04818796 T PL 04818796T PL 1687435 T3 PL1687435 T3 PL 1687435T3
Authority
PL
Poland
Prior art keywords
insect
plant
sap
dsrna
dna sequences
Prior art date
Application number
PL04818796T
Other languages
English (en)
Inventor
Peter Michael Waterhouse
Steven Whyard
Rie Jeroen Van
Original Assignee
Bayer Cropscience Nv
Commw Scient Ind Res Org
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34619455&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1687435(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Cropscience Nv, Commw Scient Ind Res Org filed Critical Bayer Cropscience Nv
Publication of PL1687435T3 publication Critical patent/PL1687435T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146Genetically Modified [GMO] plants, e.g. transgenic plants
PL04818796T 2003-11-17 2004-11-17 Odporność na owady z użyciem hamowania ekspresji genów PL1687435T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US52030603P 2003-11-17 2003-11-17
PCT/EP2004/013049 WO2005049841A1 (en) 2003-11-17 2004-11-17 Insect resistance using inhibition of gene expression
EP04818796A EP1687435B1 (en) 2003-11-17 2004-11-17 Insect resistance using inhibition of gene expression

Publications (1)

Publication Number Publication Date
PL1687435T3 true PL1687435T3 (pl) 2012-02-29

Family

ID=34619455

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04818796T PL1687435T3 (pl) 2003-11-17 2004-11-17 Odporność na owady z użyciem hamowania ekspresji genów

Country Status (6)

Country Link
US (1) US20060272049A1 (pl)
EP (1) EP1687435B1 (pl)
AT (1) ATE526407T1 (pl)
ES (1) ES2374529T3 (pl)
PL (1) PL1687435T3 (pl)
WO (1) WO2005049841A1 (pl)

Families Citing this family (101)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPR621501A0 (en) 2001-07-06 2001-08-02 Commonwealth Scientific And Industrial Research Organisation Delivery of ds rna
US7612194B2 (en) 2001-07-24 2009-11-03 Monsanto Technology Llc Nucleic acid sequences from Diabrotica virgifera virgifera LeConte and uses thereof
CA2693280C (en) * 2004-04-09 2017-09-12 Monsanto Technology Llc Compositions and methods for control of insect infestations in plants
EP2336333A1 (en) 2004-10-21 2011-06-22 Venganza Inc. Methods and materials for conferring resistance to pests and pathogens of plants
EP1807520B1 (en) * 2004-10-25 2012-07-25 Devgen NV Rna constructs
US8404927B2 (en) 2004-12-21 2013-03-26 Monsanto Technology Llc Double-stranded RNA stabilized in planta
US20060200878A1 (en) * 2004-12-21 2006-09-07 Linda Lutfiyya Recombinant DNA constructs and methods for controlling gene expression
UA98445C2 (ru) * 2005-09-16 2012-05-25 Монсанто Текнолоджи Ллс Способы генетического контроля поражения растений насекомыми и композиции, примененные для этого
US8853489B2 (en) * 2005-09-16 2014-10-07 Devgen Nv Transgenic plant-based methods for plant pests using RNAi
BRPI0615792A2 (pt) * 2005-09-16 2009-06-16 Devgen Nv métodos de controle de pestes com base no uso de rnai
WO2007080126A2 (en) 2006-01-12 2007-07-19 Devgen N.V. Dsrna as insect control agent
EP1971688B1 (en) 2006-01-12 2012-03-14 Devgen NV Dsrna as insect control agent
US8906876B2 (en) 2006-01-12 2014-12-09 Devgen Nv Methods for controlling pests using RNAi
US20070259785A1 (en) * 2006-02-13 2007-11-08 Monsanto Technology Llc SELECTING AND STABILIZING dsRNA CONSTRUCTS
CN101195821A (zh) 2006-12-04 2008-06-11 中国科学院上海生命科学研究院 利用RNAi技术改良植物抗虫性的方法
AU2008218813B2 (en) * 2007-02-20 2014-04-17 Monsanto Technology, Llc Invertebrate microRNAs
MX2009011893A (es) * 2007-05-09 2010-02-17 Devgen Nv Metodo para la transcripcion sustentable de transgenes.
AU2008308679B2 (en) * 2007-10-02 2015-01-29 Marina Biotech, Inc. Lipopeptides for delivery of nucleic acids
US8097712B2 (en) 2007-11-07 2012-01-17 Beelogics Inc. Compositions for conferring tolerance to viral disease in social insects, and the use thereof
US7968525B1 (en) 2007-12-03 2011-06-28 University Of Florida Research Foundation, Inc. Use of RNA interference to validate new termiticide target sites and a method of termite control
US8367895B2 (en) * 2008-01-17 2013-02-05 Pioneer Hi-Bred International, Inc. Compositions and methods for the suppression of target polynucleotides from the family aphididae
US8847013B2 (en) * 2008-01-17 2014-09-30 Pioneer Hi Bred International Inc Compositions and methods for the suppression of target polynucleotides from lepidoptera
US8809625B2 (en) * 2008-01-17 2014-08-19 Pioneer Hi-Bred International, Inc. Compositions and methods for the suppression of target polynucleotides from Lygus
US20090188008A1 (en) * 2008-01-17 2009-07-23 Pioneer Hi-Bred International, Inc. Compositions and methods for the suppression of target polynucleotides
WO2010140675A1 (ja) * 2009-06-05 2010-12-09 国立大学法人名古屋大学 害虫防除方法
WO2011021171A1 (en) 2009-08-21 2011-02-24 Beeologics, Llc Preventing and curing beneficial insect diseases via plant transcribed molecules
BR122018067960B8 (pt) 2009-08-28 2022-12-06 Du Pont Polinucleotídeo isolado, cassete de expressão, método para controlar uma praga de plantas do tipo coleoptera e método para obtenção de uma planta
US8962584B2 (en) 2009-10-14 2015-02-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Compositions for controlling Varroa mites in bees
AU2010305808B2 (en) * 2009-10-14 2015-03-12 The University Of Western Ontario Method to control spider mites
EP2356901A1 (en) * 2010-02-12 2011-08-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Induction of gene expression in arthropods
WO2011057825A1 (en) * 2009-11-16 2011-05-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Induction of gene expression in arthropods
MX2012010479A (es) 2010-03-08 2012-10-09 Monsanto Technology Llc Moleculas polinucleotidicas para regulacion genetica en plantas.
US8872001B2 (en) 2010-06-04 2014-10-28 Pioneer Hi Bred International Inc Compositions and methods for insecticidal control of stinkbugs
US10443068B2 (en) 2010-06-25 2019-10-15 Agrivida, Inc. Plants with engineered endogenous genes
US9598700B2 (en) 2010-06-25 2017-03-21 Agrivida, Inc. Methods and compositions for processing biomass with elevated levels of starch
US9434954B2 (en) * 2010-06-25 2016-09-06 Agrivida, Inc. Plants with altered levels of vegetative starch
KR20130130804A (ko) * 2010-12-30 2013-12-02 다우 아그로사이언시즈 엘엘씨 공포 atpase c 서브유닛을 표적화하고 딱정벌레목 해충에 대한 저항성을 부여하는 핵산 분자
US10155958B2 (en) * 2011-03-31 2018-12-18 Shanghai Institutes For Biological Sciences, Cas Method for improving plant resistance to insects
CN102212522B (zh) * 2011-04-29 2012-08-22 山东省农业科学院高新技术研究中心 一种利用rna干扰技术防治烟粉虱的方法
RU2619219C2 (ru) * 2011-07-18 2017-05-12 Девген Нв Подавление экспрессии генов у насекомых-вредителей
EP2755988B1 (en) 2011-09-13 2018-08-22 Monsanto Technology LLC Methods and compositions for weed control
US10760086B2 (en) 2011-09-13 2020-09-01 Monsanto Technology Llc Methods and compositions for weed control
CA2848680C (en) 2011-09-13 2020-05-19 Monsanto Technology Llc Methods and compositions for weed control
US9840715B1 (en) 2011-09-13 2017-12-12 Monsanto Technology Llc Methods and compositions for delaying senescence and improving disease tolerance and yield in plants
US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
US10829828B2 (en) 2011-09-13 2020-11-10 Monsanto Technology Llc Methods and compositions for weed control
EP2755466A4 (en) 2011-09-13 2015-04-15 Monsanto Technology Llc METHODS AND COMPOSITIONS FOR CONTROLLING WEEDS
EP3296402B1 (en) 2011-09-13 2020-04-15 Monsanto Technology LLC Methods and compositions for weed control
US9920326B1 (en) 2011-09-14 2018-03-20 Monsanto Technology Llc Methods and compositions for increasing invertase activity in plants
CN102363782B (zh) * 2011-10-25 2013-06-19 中国科学院华南植物园 一种水稻组蛋白脱乙酰化酶基因hdt701启动子及其应用
CN102499254B (zh) * 2011-10-28 2013-11-06 中山大学 一种蜕皮抑制类杀虫剂及其应用
WO2013158966A1 (en) 2012-04-20 2013-10-24 Futuragene Israel Ltd. Bronze bug control agents
CN104508134A (zh) 2012-04-23 2015-04-08 富优基尼以色列股份有限公司 赤桉木虱防治剂
WO2013169923A2 (en) 2012-05-08 2013-11-14 Monsanto Technology Llc Corn event mon 87411
US10240161B2 (en) 2012-05-24 2019-03-26 A.B. Seeds Ltd. Compositions and methods for silencing gene expression
RU2015101749A (ru) * 2012-06-22 2016-08-10 Зингента Партисипейшнс Аг Биологический контроль жесткокрылых вредителей
ITNA20120046A1 (it) * 2012-08-02 2014-02-03 No Self S R L Uso di acidi nucleici di sistemi biologici parassiti, patogeni e infestanti per l'inibizione e/o controllo degli stessi sistemi
UY35064A (es) 2012-10-03 2014-04-30 Futuragene Israel Ltd Agentes para el control de la avispa de las agallas
CA2888264A1 (en) 2012-10-18 2014-04-24 Monsanto Technology Llc Methods and compositions for plant pest control
CN103039494A (zh) * 2012-12-05 2013-04-17 北京大北农科技集团股份有限公司 控制害虫的方法
US10683505B2 (en) 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
MX2015008611A (es) 2013-01-01 2016-02-03 Seeds Ltd Ab Metodos para introducir dsrna en semillas de plantas para modular la expresion genetica.
US10000767B2 (en) 2013-01-28 2018-06-19 Monsanto Technology Llc Methods and compositions for plant pest control
BR112015023051A2 (pt) 2013-03-13 2017-11-14 Monsanto Technology Llc método para controle de ervas daninhas, composição herbicida, cassete de expressão microbiano e método de produção de polinucleotídeo
EP2967082A4 (en) 2013-03-13 2016-11-02 Monsanto Technology Llc METHOD AND COMPOSITIONS FOR WEED CONTROL
US20140283211A1 (en) 2013-03-14 2014-09-18 Monsanto Technology Llc Methods and Compositions for Plant Pest Control
US9920316B2 (en) * 2013-03-14 2018-03-20 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
US10568328B2 (en) 2013-03-15 2020-02-25 Monsanto Technology Llc Methods and compositions for weed control
WO2014182473A1 (en) 2013-05-08 2014-11-13 Monsanto Technology Llc Compositions and methods for deploying a transgenic refuge seed blend
US9850496B2 (en) 2013-07-19 2017-12-26 Monsanto Technology Llc Compositions and methods for controlling Leptinotarsa
JP6668236B2 (ja) 2013-07-19 2020-03-18 モンサント テクノロジー エルエルシー Leptinotarsa防除用組成物及びその方法
MX2016005778A (es) 2013-11-04 2016-12-20 Monsanto Technology Llc Composiciones y metodos para controlar infestaciones de plagas y parasitos de los artropodos.
UA119253C2 (uk) 2013-12-10 2019-05-27 Біолоджикс, Інк. Спосіб боротьби із вірусом у кліща varroa та у бджіл
BR102014031844A2 (pt) * 2013-12-20 2015-10-06 Dow Agrosciences Llc ras oposto (rop) e moléculas de ácido nucleico relacionadas que conferem resistência a pragas de coleópteros e hemípteros
AR099092A1 (es) 2014-01-15 2016-06-29 Monsanto Technology Llc Métodos y composiciones para el control de malezas utilizando polinucleótidos epsps
EP3125676A4 (en) 2014-04-01 2018-02-14 Monsanto Technology LLC Compositions and methods for controlling insect pests
CA2953347A1 (en) 2014-06-23 2015-12-30 Monsanto Technology Llc Compositions and methods for regulating gene expression via rna interference
US11807857B2 (en) 2014-06-25 2023-11-07 Monsanto Technology Llc Methods and compositions for delivering nucleic acids to plant cells and regulating gene expression
CN114009454A (zh) * 2014-07-29 2022-02-08 孟山都技术公司 用于控制昆虫害虫的组合物和方法
PT3237617T (pt) * 2014-12-23 2019-05-30 Syngenta Participations Ag Controlo biológico de pragas de coleópteros
CN108064288B (zh) 2015-01-22 2021-11-26 孟山都技术公司 用于控制叶甲属的组合物和方法
EP3302053B1 (en) 2015-06-02 2021-03-17 Monsanto Technology LLC Compositions and methods for delivery of a polynucleotide into a plant
US10655136B2 (en) 2015-06-03 2020-05-19 Monsanto Technology Llc Methods and compositions for introducing nucleic acids into plants
CN105274119B (zh) * 2015-10-10 2018-11-27 华南农业大学 细胞壁酸性转化酶抑制子基因LcCIF及其应用
CN109312344A (zh) 2016-01-26 2019-02-05 孟山都技术公司 用于控制昆虫害虫的组合物和方法
US11085052B2 (en) 2016-05-03 2021-08-10 University Of Manitoba Plants and methods for controlling fungal plant pathogens
BR102016013023A2 (pt) * 2016-06-07 2017-12-19 Embrapa- Empresa Brasileira De Pesquisa Agropecuária Method of producing insect resistant plague prague, insective resistant plant plague, plant seed and nucleic acid molecules used obtaining such plant
US20180023076A1 (en) * 2016-07-25 2018-01-25 The United States Of America, As Represented By The Secretary Of Agriculture Double strand rna delivery system for plant-sap-feeding insects
WO2018046312A2 (en) * 2016-09-06 2018-03-15 Syngenta Participations Ag Improvements in or relating to gene silencing
US11974574B2 (en) * 2017-02-24 2024-05-07 Flagship Pioneering Innovations V, Inc. Compositions and related methods for modulating endosymbionts
WO2018204398A1 (en) * 2017-05-01 2018-11-08 Donald Danforth Plant Science Center Rnai approach for crop pest protection
CN107760682B (zh) * 2017-10-18 2020-12-18 云南大学 一种可用于分子防治害虫的核酸序列及其应用
KR102008064B1 (ko) * 2017-11-07 2019-08-06 서울대학교산학협력단 애멸구의 핵수용체 E75 유전자에 특이적인 dsRNA를 이용한 애멸구 매개 바이러스 방제용 조성물 및 방법
CA3100442A1 (en) * 2018-05-14 2019-11-21 Cas Center For Excellence In Molecular Plant Sciences Rnai target gene that is highly lethal to aphids and use thereof
CN109077028B (zh) * 2018-08-28 2023-07-18 中国农业科学院蔬菜花卉研究所 对西花蓟马进行rna干扰的方法及装置
WO2020215149A1 (en) * 2019-04-24 2020-10-29 University Of Manitoba Flea beetle-specific rnai-based pesticides
CN110592117B (zh) * 2019-08-05 2021-07-20 华南农业大学 高致死基因vATPase B及其防瓢虫应用
CA3147794A1 (en) * 2019-09-06 2021-03-11 Kasimalai AZHAKANADAM Promoters for regulation of gene expression in plants
WO2021058659A1 (en) 2019-09-26 2021-04-01 Bayer Aktiengesellschaft Rnai-mediated pest control
WO2023010013A1 (en) * 2021-07-27 2023-02-02 BASF Agricultural Solutions Seed US LLC Viral coat delivery of insect resistance genes in plants
CN116790679B (zh) * 2023-05-30 2024-03-12 华南师范大学 德国小蠊Dnmt1基因在肢体再生及害虫防治中的应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2094658A1 (en) * 1992-04-23 1993-10-24 Martin Sumner-Smith Intracellular delivery of biochemical agents
DE19881219B4 (de) * 1997-08-26 2011-12-01 Schaeffler Technologies Gmbh & Co. Kg Hydrodynamischer Drehmomentwandler
AUPP135698A0 (en) * 1998-01-15 1998-02-05 Commonwealth Scientific And Industrial Research Organisation Insectical modalities
GB9827152D0 (en) * 1998-07-03 1999-02-03 Devgen Nv Characterisation of gene function using double stranded rna inhibition
US6326193B1 (en) * 1999-11-05 2001-12-04 Cambria Biosciences, Llc Insect control agent
AU2047001A (en) * 1999-11-24 2001-06-04 Dna Plant Technology Corporation Methods of inhibiting plant parasitic nematodes and insect pests by expression of nematode and insect specific double-stranded rna in plants
AUPR621501A0 (en) * 2001-07-06 2001-08-02 Commonwealth Scientific And Industrial Research Organisation Delivery of ds rna
US6766613B2 (en) * 2001-11-16 2004-07-27 University Of Florida Research Foundation, Inc. Materials and methods for controlling pests
US6655659B2 (en) * 2002-02-08 2003-12-02 Fisher Controls International Inc. One-piece sanitary seat ring
AU2003209814B2 (en) * 2002-03-14 2008-12-04 Commonwealth Scientific & Industrial Research Organisation Modified gene-silencing RNA and uses thereof
CA2693280C (en) * 2004-04-09 2017-09-12 Monsanto Technology Llc Compositions and methods for control of insect infestations in plants
UA98445C2 (ru) * 2005-09-16 2012-05-25 Монсанто Текнолоджи Ллс Способы генетического контроля поражения растений насекомыми и композиции, примененные для этого
WO2007080126A2 (en) * 2006-01-12 2007-07-19 Devgen N.V. Dsrna as insect control agent

Also Published As

Publication number Publication date
EP1687435A1 (en) 2006-08-09
WO2005049841B1 (en) 2005-09-09
ATE526407T1 (de) 2011-10-15
US20060272049A1 (en) 2006-11-30
EP1687435B1 (en) 2011-09-28
ES2374529T3 (es) 2012-02-17
WO2005049841A1 (en) 2005-06-02

Similar Documents

Publication Publication Date Title
PL1687435T3 (pl) Odporność na owady z użyciem hamowania ekspresji genów
EP4170029A3 (en) Modifying the specifity of plant non-coding rna molecules for silencing gene expression
AU2003261231A1 (en) Modified small interfering rna molecules and methods of use
ATE479740T1 (de) Zusammensetzungen für bakteriell vermitteltes gen-silencing sowie verfahren zur verwendung davon
WO2008156702A3 (en) Bacteria mediated gene silencing
WO2013090457A3 (en) In vivo delivery of oligonucleotides
AR039717A1 (es) Construcciones de arn de intrones cadena doble y usos de las mismas
WO2004065613A3 (en) Inducible small interfering rna (sirna) expression constructs for targeted gene silencing
WO2006119266A3 (en) Human micrornas and methods for inhibiting same
AU2003256615A1 (en) Methods and compositions relating to gene silencing
WO2006029350A3 (en) Methods and compositions for tailing and amplifying rna
AR074672A1 (es) Genes que codifican toxinas contra nematodos
WO2004007718A3 (en) Rna-interference by single-stranded rna molecules
EP2302062A8 (en) Identification of E2F target genes and uses thereof
WO2010014857A3 (en) Chromosome therapy
NZ599998A (en) Supercoiled minicircle dna for gene therapy applications
MX2007004686A (es) Moleculas de arn de multidominio que comprenden al menos un aptamero para suministrar arn de doble hebra a organismos nocivos.
WO2005097205A3 (en) Dna virus microrna and methods for inhibiting same
WO2005086896A3 (en) Delivery vectors for short interfering rna, micro-rna and antisense rna
WO2012078949A3 (en) Methods and compositions using small interfering rna (sirna) for nematode control in plants
Weissenboeck et al. Optochemical control of mRNA translation in eukaryotes
WO2005045032A3 (en) RNA INTERFERENCE MEDIATED INHIBITION OF EARLY GROWTH RESPONSE GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
WO2005045036A3 (en) Rna interference mediated inhibition of hairless (hr) gene expression using short interfering nucleic acid (sina)
WO2009008645A3 (en) Linear double-stranded rna molecule interfering with different target genes
WO2005014811A3 (en) RNA INTERFERENCE MEDIATED INHIBITION OF XIAP GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)