PL1625164T3 - Sposób wykrywania proBNP z użyciem przeciwciała monoklonalnego wiążącego się z aminokwasami 42-46 - Google Patents

Sposób wykrywania proBNP z użyciem przeciwciała monoklonalnego wiążącego się z aminokwasami 42-46

Info

Publication number
PL1625164T3
PL1625164T3 PL04732282T PL04732282T PL1625164T3 PL 1625164 T3 PL1625164 T3 PL 1625164T3 PL 04732282 T PL04732282 T PL 04732282T PL 04732282 T PL04732282 T PL 04732282T PL 1625164 T3 PL1625164 T3 PL 1625164T3
Authority
PL
Poland
Prior art keywords
amino acids
monoclonal antibody
antibody binding
probnp
native probnp
Prior art date
Application number
PL04732282T
Other languages
English (en)
Inventor
Volker Klemt
Anneliese Borgya
Andreas Gallusser
Michael Grol
Klaus Hallermayer
Christoph Seidel
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33427054&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1625164(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PL1625164T3 publication Critical patent/PL1625164T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/58Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • C12N5/12Fused cells, e.g. hybridomas
    • C12N5/16Animal cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/811Test for named disease, body condition or organ function

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • Cardiology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL04732282T 2003-05-12 2004-05-12 Sposób wykrywania proBNP z użyciem przeciwciała monoklonalnego wiążącego się z aminokwasami 42-46 PL1625164T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03010591 2003-05-12
EP04732282A EP1625164B1 (en) 2003-05-12 2004-05-12 Method of detecting probnp with a monoclonal antibody binding to the amino acids 42-46
PCT/EP2004/005092 WO2004099253A1 (en) 2003-05-12 2004-05-12 Method of detecting probnp with a monoclonal antibody binding to the amino acid 41-46

Publications (1)

Publication Number Publication Date
PL1625164T3 true PL1625164T3 (pl) 2011-12-30

Family

ID=33427054

Family Applications (3)

Application Number Title Priority Date Filing Date
PL04732282T PL1625164T3 (pl) 2003-05-12 2004-05-12 Sposób wykrywania proBNP z użyciem przeciwciała monoklonalnego wiążącego się z aminokwasami 42-46
PL10172014T PL2256132T3 (pl) 2003-05-12 2004-05-12 Sposób wykrywania proBNP z zastosowaniem przeciwciała monoklonalnego
PL04732278T PL1625163T3 (pl) 2003-05-12 2004-05-12 Sposoby wykrywania proBMP przeciwciałem monoklonalnym wiążącym się z aminokwasami 38-43

Family Applications After (2)

Application Number Title Priority Date Filing Date
PL10172014T PL2256132T3 (pl) 2003-05-12 2004-05-12 Sposób wykrywania proBNP z zastosowaniem przeciwciała monoklonalnego
PL04732278T PL1625163T3 (pl) 2003-05-12 2004-05-12 Sposoby wykrywania proBMP przeciwciałem monoklonalnym wiążącym się z aminokwasami 38-43

Country Status (16)

Country Link
US (4) US7264939B2 (pl)
EP (4) EP2949669A1 (pl)
JP (4) JP4430066B2 (pl)
KR (2) KR20080011467A (pl)
CN (3) CN1784425A (pl)
AT (2) ATE522546T1 (pl)
AU (1) AU2004235974B2 (pl)
BR (1) BRPI0410261B8 (pl)
CA (2) CA2522378C (pl)
DK (3) DK1625163T3 (pl)
ES (3) ES2369008T3 (pl)
HK (1) HK1097855A1 (pl)
HU (1) HUE025169T2 (pl)
MX (1) MXPA05011826A (pl)
PL (3) PL1625164T3 (pl)
WO (2) WO2004099253A1 (pl)

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DK1625163T3 (da) * 2003-05-12 2011-12-05 Hoffmann La Roche Fremgangsmåde til at påvise proBNP med en monoklonal antistofbinding til aminosyrerne 38-43
WO2004105575A2 (en) * 2003-05-29 2004-12-09 Trustee Of Darmouth College A method for detecting cardiac ischemia via changes in b-natriuretic peptide levels
DE10355731A1 (de) 2003-11-28 2005-06-30 Roche Diagnostics Gmbh Analytischer Sandwichtest zur Bestimmung von NT-proBNP
ES2288718T3 (es) * 2004-07-07 2008-01-16 F. Hoffmann-La Roche Ag Panel de multiples marcadores para la diabetes de tipo 1 y de tipo 2.
AT500800B1 (de) * 2004-09-08 2008-07-15 Biomedica Medizinprodukte Gmbh Verfahren zur bestimmung von probnp
WO2008089994A1 (en) 2007-01-25 2008-07-31 Roche Diagnostics Gmbh Use of igfbp-7 in the assessment of heart failure
KR100836322B1 (ko) * 2007-08-31 2008-06-09 현대자동차주식회사 차량용 흡음재 제작장치 및 방법
US9482677B2 (en) 2008-02-27 2016-11-01 Scios Inc. Method, composition and device for sampling natriuretic peptides in a biological fluid
EP2274622B1 (en) 2008-04-30 2014-10-08 The Governing Council of the University of Toronto Use of sfrp-3 in the assessment of heart failure
CN102549436A (zh) 2009-07-27 2012-07-04 霍夫曼-拉罗奇有限公司 mimecan在评价心力衰竭中的用途
BR112012011230A2 (pt) * 2009-11-13 2016-04-05 Bg Medicine Inc fatores de risco e previsão de infarto do miocárdio
AU2011285694B2 (en) 2010-08-04 2014-12-18 Idexx Laboratories, Inc. Detection of degradation products of canine NT-proBNP
AU2012262154B2 (en) 2011-05-31 2016-08-04 Idexx Laboratories, Inc. Detection of degradation products of feline NT-proBNP
WO2013042603A1 (ja) * 2011-09-20 2013-03-28 コニカミノルタホールディングス株式会社 検体希釈用液、それを用いたキットおよび蛍光測定方法
US20140273273A1 (en) 2012-11-01 2014-09-18 Christie Mitchell Ballantyne Biomarkers to improve prediction of heart failure risk
CN103304665A (zh) * 2013-05-21 2013-09-18 上海贝西生物科技有限公司 一种抗氨基末端脑利钠肽前体单克隆抗体及其应用
EP3206032B1 (en) * 2014-10-10 2019-02-27 Akira Matsumori Method for detecting cardiac failure patient, method for discrimination of cardiac disease, test reagent for cardiac failure, test kit for cardiac failure, device for detecting cardiac failure, and program for detecting cardiac failure
EP3360570A1 (en) 2017-02-13 2018-08-15 Roche Diagnostics GmbH Antibodies recognizing genetic variants
JP7203034B2 (ja) * 2017-10-02 2023-01-12 大塚製薬株式会社 アナライトの検出方法
EP3779438A4 (en) * 2018-04-13 2022-01-26 Kyoritsu Seiyaku Corporation PROCEDURE FOR DETECTING HEART FAILURE, INSTRUMENT FOR DETECTING HEART FAILURE, SANDWICH IMMUNOASSAY PROCEDURE AND ANTIBODY COMBINATION
CN108752480B (zh) * 2018-05-30 2022-03-29 中元汇吉生物技术股份有限公司 一种免疫原组合物、其制备方法及其用途
US12001939B2 (en) 2018-12-11 2024-06-04 Eko.Ai Pte. Ltd. Artificial intelligence (AI)-based guidance for an ultrasound device to improve capture of echo image views
US11446009B2 (en) 2018-12-11 2022-09-20 Eko.Ai Pte. Ltd. Clinical workflow to diagnose heart disease based on cardiac biomarker measurements and AI recognition of 2D and doppler modality echocardiogram images
US11931207B2 (en) 2018-12-11 2024-03-19 Eko.Ai Pte. Ltd. Artificial intelligence (AI) recognition of echocardiogram images to enhance a mobile ultrasound device
CN111487222B (zh) * 2019-01-28 2023-11-14 上海乐合生物科技有限公司 一种检测bnp的spr芯片的制备方法
JP2022544394A (ja) 2019-08-13 2022-10-18 ゲンティアン アクティーゼルスカブ Nt-プロbnpの定量のための高感度粒子増感アッセイ
WO2022069658A1 (en) 2020-09-30 2022-04-07 F. Hoffmann-La Roche Ag Circulating total-nt-probnp (glycosylated and unglycosylated nt-probnp) and its ratio with nt-probnp (unglycosylated nt-probnp) in the assessment of atrial fibrillation
CN112986586A (zh) * 2021-02-20 2021-06-18 广东菲鹏生物有限公司 一种氨基末端脑尿钠肽检测方法和试剂盒
CN112964885B (zh) * 2021-02-20 2022-11-11 广东菲鹏生物有限公司 一种氨基末端脑尿钠肽检测方法和试剂盒
IL311792A (en) 2021-10-01 2024-05-01 Gentian As A new method for determining the concentration of N-terminal prohormone BNP (NT-PROBNP) in a sample
WO2023175176A1 (en) 2022-03-18 2023-09-21 Roche Diagnostics Gmbh Cmybpc marker combinations for early discrimination of type 2 versus type 1 acute myocardial infarction
WO2023175152A1 (en) 2022-03-18 2023-09-21 Roche Diagnostics Gmbh Troponin marker combinations for early discrimination of type 2 versus type 1 acute myocardial infarction

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JP2665850B2 (ja) 1991-11-14 1997-10-22 塩野義製薬株式会社 hBNPのC端を認識するモノクロ−ナル抗体
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US20040096919A1 (en) * 2002-11-18 2004-05-20 Michelle Davey Polyclonal-monoclonal ELISA assay for detecting N-terminus proBNP
DK1625163T3 (da) * 2003-05-12 2011-12-05 Hoffmann La Roche Fremgangsmåde til at påvise proBNP med en monoklonal antistofbinding til aminosyrerne 38-43

Also Published As

Publication number Publication date
CN1832964A (zh) 2006-09-13
EP2256132A1 (en) 2010-12-01
HK1097855A1 (en) 2007-07-06
MXPA05011826A (es) 2006-01-26
AU2004235974B2 (en) 2008-02-14
ES2548327T3 (es) 2015-10-15
US7264938B2 (en) 2007-09-04
HUE025169T2 (en) 2016-02-29
DK2256132T3 (en) 2015-07-13
DK1625163T3 (da) 2011-12-05
BRPI0410261B1 (pt) 2020-03-10
US7807380B2 (en) 2010-10-05
KR20060003905A (ko) 2006-01-11
JP2010011860A (ja) 2010-01-21
JP4430066B2 (ja) 2010-03-10
ATE517124T1 (de) 2011-08-15
EP1625164B1 (en) 2011-07-20
EP1625163A1 (en) 2006-02-15
CA2522378A1 (en) 2004-11-18
CN101967190A (zh) 2011-02-09
CA2522378C (en) 2011-03-29
JP4834136B2 (ja) 2011-12-14
CN1784425A (zh) 2006-06-07
ES2372282T3 (es) 2012-01-18
JP5649631B2 (ja) 2015-01-07
EP1625163B8 (en) 2011-11-02
WO2004099252A1 (en) 2004-11-18
BRPI0410261B8 (pt) 2021-07-27
ATE522546T1 (de) 2011-09-15
EP2256132B1 (en) 2015-04-01
PL1625163T3 (pl) 2012-01-31
EP2949669A1 (en) 2015-12-02
EP1625163B1 (en) 2011-08-31
US20070099241A1 (en) 2007-05-03
PL2256132T3 (pl) 2016-08-31
ES2369008T3 (es) 2011-11-24
JP2007535470A (ja) 2007-12-06
WO2004099253A1 (en) 2004-11-18
US20060110776A1 (en) 2006-05-25
US7811770B2 (en) 2010-10-12
CA2522747A1 (en) 2004-11-18
JP2007525427A (ja) 2007-09-06
BRPI0410261A (pt) 2006-05-16
KR100857752B1 (ko) 2008-09-11
US20070117156A1 (en) 2007-05-24
US20060110775A1 (en) 2006-05-25
EP1625164A1 (en) 2006-02-15
KR20080011467A (ko) 2008-02-04
JP5128125B2 (ja) 2013-01-23
CN100497393C (zh) 2009-06-10
JP2013018784A (ja) 2013-01-31
CA2522747C (en) 2012-08-14
AU2004235974A1 (en) 2004-11-18
US7264939B2 (en) 2007-09-04
DK1625164T3 (da) 2011-10-31

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