PL112198B1 - Process for preparing novel derivatives of bis-/nitrosoureido/-polyols - Google Patents

Process for preparing novel derivatives of bis-/nitrosoureido/-polyols Download PDF

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Publication number
PL112198B1
PL112198B1 PL1978208436A PL20843678A PL112198B1 PL 112198 B1 PL112198 B1 PL 112198B1 PL 1978208436 A PL1978208436 A PL 1978208436A PL 20843678 A PL20843678 A PL 20843678A PL 112198 B1 PL112198 B1 PL 112198B1
Authority
PL
Poland
Prior art keywords
bis
chloroethyl
mixture
water
mol
Prior art date
Application number
PL1978208436A
Other languages
English (en)
Polish (pl)
Other versions
PL208436A1 (pl
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of PL208436A1 publication Critical patent/PL208436A1/xx
Publication of PL112198B1 publication Critical patent/PL112198B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/66—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to halogen atoms or to nitro or nitroso groups
    • C07C275/68—N-nitroso ureas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polyurethanes Or Polyureas (AREA)
PL1978208436A 1977-12-29 1978-07-15 Process for preparing novel derivatives of bis-/nitrosoureido/-polyols PL112198B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77GO1386A HU176101B (en) 1977-12-29 1977-12-29 Process for producing bis-bracket-nitrozo-ureido-bracket closed-polyol derivatives

Publications (2)

Publication Number Publication Date
PL208436A1 PL208436A1 (pl) 1979-07-02
PL112198B1 true PL112198B1 (en) 1980-09-30

Family

ID=10996842

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1978208436A PL112198B1 (en) 1977-12-29 1978-07-15 Process for preparing novel derivatives of bis-/nitrosoureido/-polyols

Country Status (28)

Country Link
US (1) US4237273A (Direct)
JP (1) JPS5495517A (Direct)
AT (1) AT360045B (Direct)
AU (1) AU523845B2 (Direct)
BE (1) BE868988A (Direct)
BG (1) BG30016A3 (Direct)
CA (1) CA1108182A (Direct)
CH (1) CH639363A5 (Direct)
CS (1) CS201010B2 (Direct)
DD (1) DD137224A5 (Direct)
DE (1) DE2831094A1 (Direct)
DK (1) DK155047C (Direct)
ES (1) ES471778A1 (Direct)
FI (1) FI69058C (Direct)
FR (1) FR2415096A1 (Direct)
GB (1) GB2011382B (Direct)
GR (1) GR64891B (Direct)
HU (1) HU176101B (Direct)
IL (1) IL55138A (Direct)
IT (1) IT1097647B (Direct)
NL (1) NL7807587A (Direct)
NO (1) NO149960C (Direct)
PL (1) PL112198B1 (Direct)
PT (1) PT68301A (Direct)
RO (1) RO77027A (Direct)
SE (1) SE446529B (Direct)
YU (1) YU41314B (Direct)
ZA (1) ZA783980B (Direct)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2459231A1 (fr) 1979-06-19 1981-01-09 Anvar Nouveaux derives de la cystamine utiles comme medicaments
JPS5775993A (en) * 1980-10-30 1982-05-12 Tetsuo Suami Novel nitrosourea derivative and its preparation
EP0428849A3 (en) * 1989-09-28 1991-07-31 Hoechst Aktiengesellschaft Retroviral protease inhibitors
AU8320691A (en) * 1990-07-06 1992-02-04 Smithkline Beecham Corporation Inhibitors of retroviral proteases
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH518270A (de) * 1969-03-07 1972-01-31 Hoffmann La Roche Verfahren zur Herstellung von Nitrosoharnstoffverbindungen
JPS5135382B2 (Direct) * 1972-08-04 1976-10-01
JPS50128266A (Direct) * 1974-03-26 1975-10-09
JPS5126876A (en) * 1974-08-08 1976-03-05 Suami T Shinkina nitorosonyosojudotaino seizohoho
US4066750A (en) * 1976-08-02 1978-01-03 Astra Chemical Products Ab Lactosyl substituted ureides in ruminant feedstuff
JPS5331664A (en) * 1976-09-02 1978-03-25 Suami T Production of novel nitroso urea derivatives
JPS5395917A (en) * 1977-02-03 1978-08-22 Tokyo Tanabe Co Process for preparing nitrosourea derivative of glucopyranose
US4148921A (en) * 1977-07-13 1979-04-10 Suami T Antitumor agents

Also Published As

Publication number Publication date
HU176101B (en) 1980-12-28
IT7825682A0 (it) 1978-07-14
GR64891B (en) 1980-06-06
JPS6250461B2 (Direct) 1987-10-24
ZA783980B (en) 1979-07-25
JPS5495517A (en) 1979-07-28
NO149960B (no) 1984-04-16
NL7807587A (nl) 1979-07-03
IL55138A (en) 1982-05-31
CS201010B2 (en) 1980-10-31
FR2415096A1 (fr) 1979-08-17
PT68301A (de) 1978-08-01
CH639363A5 (de) 1983-11-15
FR2415096B1 (Direct) 1982-12-10
US4237273A (en) 1980-12-02
SE446529B (sv) 1986-09-22
FI782238A7 (fi) 1979-06-30
DK155047B (da) 1989-01-30
NO782447L (no) 1979-05-02
ES471778A1 (es) 1979-02-01
FI69058B (fi) 1985-08-30
YU169978A (en) 1982-10-31
AU523845B2 (en) 1982-08-19
YU41314B (en) 1987-02-28
DE2831094C2 (Direct) 1988-12-15
ATA500178A (de) 1980-05-15
GB2011382A (en) 1979-07-11
IL55138A0 (en) 1978-09-29
AU3802778A (en) 1980-01-17
BE868988A (fr) 1979-01-15
DE2831094A1 (de) 1979-07-12
NO149960C (no) 1984-07-25
CA1108182A (en) 1981-09-01
DK155047C (da) 1989-06-26
IT1097647B (it) 1985-08-31
SE7807804L (sv) 1979-06-30
PL208436A1 (pl) 1979-07-02
RO77027A (ro) 1981-11-04
DD137224A5 (de) 1979-08-22
FI69058C (fi) 1985-12-10
AT360045B (de) 1980-12-10
BG30016A3 (bg) 1981-03-16
DK317878A (da) 1979-06-30
GB2011382B (en) 1982-08-18

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