PH30718A - Improved intravaginal treatment of vaginal infectios with buffered metronidazole compositions. - Google Patents

Improved intravaginal treatment of vaginal infectios with buffered metronidazole compositions.

Info

Publication number
PH30718A
PH30718A PH40620A PH40620A PH30718A PH 30718 A PH30718 A PH 30718A PH 40620 A PH40620 A PH 40620A PH 40620 A PH40620 A PH 40620A PH 30718 A PH30718 A PH 30718A
Authority
PH
Philippines
Prior art keywords
infectios
vaginal
metronidazole
buffered
composition
Prior art date
Application number
PH40620A
Other languages
English (en)
Inventor
Robert J Borgman
Original Assignee
Curatek Pharmaceuticals Ltd Pa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curatek Pharmaceuticals Ltd Pa filed Critical Curatek Pharmaceuticals Ltd Pa
Publication of PH30718A publication Critical patent/PH30718A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/04—Amoebicides

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PH40620A 1989-06-06 1990-06-05 Improved intravaginal treatment of vaginal infectios with buffered metronidazole compositions. PH30718A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36227389A 1989-06-06 1989-06-06

Publications (1)

Publication Number Publication Date
PH30718A true PH30718A (en) 1997-09-23

Family

ID=23425444

Family Applications (1)

Application Number Title Priority Date Filing Date
PH40620A PH30718A (en) 1989-06-06 1990-06-05 Improved intravaginal treatment of vaginal infectios with buffered metronidazole compositions.

Country Status (21)

Country Link
EP (1) EP0404376B1 (ro)
JP (1) JP2999820B2 (ro)
KR (1) KR0169487B1 (ro)
CN (1) CN1054507C (ro)
AT (1) ATE103176T1 (ro)
AU (1) AU635752B2 (ro)
BR (1) BR9006793A (ro)
CA (1) CA1337279C (ro)
DE (1) DE69007547T2 (ro)
DK (1) DK0404376T3 (ro)
ES (1) ES2062366T3 (ro)
HU (1) HU207795B (ro)
IE (1) IE65413B1 (ro)
IL (1) IL94619A (ro)
PH (1) PH30718A (ro)
PL (1) PL164128B1 (ro)
RO (1) RO109156B1 (ro)
RU (1) RU2032402C1 (ro)
WO (1) WO1990014832A1 (ro)
YU (1) YU47950B (ro)
ZA (1) ZA904413B (ro)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5592949A (en) * 1994-06-29 1997-01-14 Moench; Thomas R. Device for acidic buffering and method for inactivation of pathogens
GB9610359D0 (en) * 1996-05-17 1996-07-24 Edko Trading Representation Pharmaceutical compositions
GB9626513D0 (en) * 1996-12-20 1997-02-05 Bioglan Ireland R & D Ltd A pharmaceutical composition
RU2154477C1 (ru) * 1998-12-10 2000-08-20 Новокузнецкий государственный институт усовершенствования врачей Способ лечения хронического трихомониаза
RU2195945C2 (ru) * 2000-02-14 2003-01-10 Владивостокский государственный медицинский университет Способ лечения инфекций, передаваемых половым путем
RU2195943C2 (ru) * 2000-02-14 2003-01-10 Владивостокский государственный медицинский университет Способ лечения гонореи
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
DE10114244A1 (de) * 2001-03-22 2002-10-02 Heraeus Kulzer Gmbh & Co Kg Antibiotikum-/Antibiotika-Zubereitung mit retardierender Wirkstofffreisetzung
JP4959907B2 (ja) * 2001-03-27 2012-06-27 ワーナー チルコット（アイルランド）リミティド 抗菌剤投与のための膣内用ドラッグデリバリーデバイス
RU2180567C1 (ru) * 2001-05-03 2002-03-20 Новокузнецкий государственный институт усовершенствования врачей Способ лечения хронического рецидивирующего трихомониаза
RU2212238C2 (ru) * 2001-11-05 2003-09-20 Новокузнецкий государственный институт усовершенствования врачей Способ лечения рецидивирующего урогенитального кандидоза на фоне трихомониаза
GB0130666D0 (en) * 2001-12-21 2002-02-06 Accantla Holdings Ltd Absorbent tampons
US6899890B2 (en) * 2002-03-20 2005-05-31 Kv Pharmaceutical Company Bioadhesive drug delivery system
RU2221574C2 (ru) * 2002-03-21 2004-01-20 Саратовский государственный медицинский университет Способ лечения хронического трихомонадного эндоцервицита
US7417013B2 (en) 2002-05-01 2008-08-26 Mcneil-Ppc, Inc. Warming and nonirritating lubricant compositions and method of comparing irritation
EP1501478A1 (en) * 2002-05-01 2005-02-02 McNEIL-PPC, INC. Warming and nonirritating anhydrous lubricant compositions
US7658941B2 (en) 2002-05-01 2010-02-09 Johnson & Johnson Consumer Companies, Inc. Warming and nonirritating lubricant compositions and method of comparing irritation
AU2003234311A1 (en) * 2002-05-01 2003-11-17 Selig Sealing Products, Inc. Warming and nonirritating lubricant antifungal gel compositions
US7695730B2 (en) 2002-05-01 2010-04-13 Mcneil-Ppc, Inc. Warming and nonirritating lubricant compositions and method of comparing irritation
US7005408B2 (en) * 2002-05-01 2006-02-28 Mcneil-Ppc, Inc. Warming and nonirritating lubricant compositions and method of comparing irritation
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US20060140984A1 (en) 2002-10-25 2006-06-29 Foamix Ltd. Cosmetic and pharmaceutical foam
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US20050186142A1 (en) * 2002-10-25 2005-08-25 Foamix Ltd. Kit and composition of imidazole with enhanced bioavailability
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
RU2240781C1 (ru) * 2003-06-05 2004-11-27 Уральский научно-исследовательский институт дерматовенерологии и иммунопатологии Способ лечения воспалительных процессов вульвы и влагалища
EP1635847B1 (en) * 2003-06-13 2019-07-31 IDH Holding ApS Treatment of symptoms associated with bacterial vaginosis
RU2236851C1 (ru) * 2003-06-16 2004-09-27 Красноярская государственная медицинская академия Способ местного лечения бактериального вагиноза
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
MY144021A (en) * 2003-09-19 2011-07-29 Drugtech Corp Pharmaceutical delivery system
US20060140990A1 (en) * 2003-09-19 2006-06-29 Drugtech Corporation Composition for topical treatment of mixed vaginal infections
RU2249821C1 (ru) * 2004-04-27 2005-04-10 Государственное учреждение "Московский научно-исследовательский институт эпидемиологии и микробиологии им. Г.Н. Габричевского Министерства здравоохранения Российской Федерации" Способ оценки микробиоценоза влагалища
WO2006016869A1 (en) * 2004-07-08 2006-02-16 Drugtech Corporation Delivery system
RU2275918C1 (ru) * 2005-01-11 2006-05-10 ГОУ ВПО "Красноярская государственная медицинская академия Министерства здравоохранения РФ" Способ лечения хронического сальпингоофорита
US7851419B2 (en) 2005-09-12 2010-12-14 Nawaz Ahmad Substantially anhydrous sprayable personal lubricant
US20070059250A1 (en) * 2005-09-12 2007-03-15 Nawaz Ahmad Sprayable personal lubricant
KR20080083190A (ko) * 2006-01-05 2008-09-16 드러그테크 코포레이션 외음질 표면에 생체접착을 위한 약물 전달 시스템
CN101374501A (zh) * 2006-01-05 2009-02-25 药物技术公司 组合物及其使用方法
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
RU2356535C2 (ru) * 2007-07-23 2009-05-27 Закрытое Акционерное Общество "Биокад" Суппозитории комбинированного действия для лечения инфекционных гинекологических заболеваний (варианты)
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
WO2009069006A2 (en) 2007-11-30 2009-06-04 Foamix Ltd. Foam containing benzoyl peroxide
US8518376B2 (en) 2007-12-07 2013-08-27 Foamix Ltd. Oil-based foamable carriers and formulations
WO2009090495A2 (en) 2007-12-07 2009-07-23 Foamix Ltd. Oil and liquid silicone foamable carriers and formulations
WO2009090558A2 (en) 2008-01-14 2009-07-23 Foamix Ltd. Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses
WO2010079373A1 (en) * 2009-01-09 2010-07-15 EGIS GYOGYSZERGYAR, Nyilvánosan, Müködö Improved pharmaceutical formulation
WO2010125470A2 (en) 2009-04-28 2010-11-04 Foamix Ltd. Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof
CA2769625C (en) 2009-07-29 2017-04-11 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
CA2769677A1 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
AU2010302350B2 (en) 2009-10-02 2015-06-18 Journey Medical Corporation Surfactant-free water-free foamable compositions, breakable foams and gels and their uses
RU2428173C1 (ru) * 2010-06-03 2011-09-10 Общество с ограниченной ответственностью "ЦитоНИР" (ООО "ЦитоНИР") Фармацевтическая композиция для лечения заболеваний нижнего отдела мочеполовой системы
CA3054236A1 (en) * 2011-06-28 2013-01-03 Chemo Research Sl High dosage mucoadhesive metronidazole aqueous-based gel formulations and their use to treat bacterial vaginosis
EP3013368A1 (en) 2013-06-25 2016-05-04 Mission Pharmacal Company Novel formulations for the treatment of vaginal disorders
US10398641B2 (en) 2016-09-08 2019-09-03 Foamix Pharmaceuticals Ltd. Compositions and methods for treating rosacea and acne
RU2730021C1 (ru) * 2019-10-08 2020-08-14 Общество с ограниченной ответственностью "Научно-производственная фирма ВЕРТА" Средство местного применения для лечения инфекционных вагинитов
CN112773780A (zh) * 2019-11-11 2021-05-11 深圳优丽康生物技术有限公司 一种阴道外阴用组合物及其用途
RU2726123C1 (ru) * 2019-12-20 2020-07-09 Федеральное государственное бюджетное учреждение науки Оренбургский федеральный исследовательский центр Уральского отделения Российской академии наук Способ лечения трихомониаза у женщин
US11529346B2 (en) * 2020-06-18 2022-12-20 National Medical Supply, LLC Vaginal gel
EP4171513A4 (en) * 2020-06-30 2024-07-17 VIREO Systems, Inc. COMPOSITIONS FOR ODOUR AND ITCHING CONTROL AND METHODS AND DEVICES FOR THEIR ADMINISTRATION
CN115737551B (zh) * 2022-12-06 2025-08-05 天津市保灵动物保健品有限公司 一种氟苯尼考甲硝唑滴耳液及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0024023B2 (de) * 1979-08-11 1992-11-11 Bayer Ag Antimykotische Mittel mit höherer Freisetzung der Wirkstoffe
US4602040A (en) * 1983-04-18 1986-07-22 Warner-Lambert Company Meclofenamic acid topical pharmaceutical composition
US4837378A (en) * 1986-01-15 1989-06-06 Curatek Pharmaceuticals, Inc. Topical metronidazole formulations and therapeutic uses thereof
GB8607159D0 (en) * 1986-03-22 1986-04-30 Smith & Nephew Ass Pharmaceutical composition
SE8603338D0 (sv) * 1986-08-07 1986-08-07 Bjorn Andersch Medel for behandling av tillstand i slidan

Also Published As

Publication number Publication date
WO1990014832A1 (en) 1990-12-13
BR9006793A (pt) 1991-08-06
YU47950B (sh) 1996-07-24
JPH04500365A (ja) 1992-01-23
IE902011L (en) 1990-12-06
IL94619A (en) 1995-01-24
HUT56490A (en) 1991-09-30
RU2032402C1 (ru) 1995-04-10
IE65413B1 (en) 1995-10-18
CN1054507C (zh) 2000-07-19
DE69007547D1 (de) 1994-04-28
ZA904413B (en) 1991-04-24
HU904720D0 (en) 1991-07-29
CA1337279C (en) 1995-10-10
ATE103176T1 (de) 1994-04-15
AU635752B2 (en) 1993-04-01
EP0404376A2 (en) 1990-12-27
IL94619A0 (en) 1991-04-15
DE69007547T2 (de) 1994-07-14
EP0404376B1 (en) 1994-03-23
DK0404376T3 (da) 1994-05-24
YU170090A (sh) 1994-04-05
RO109156B1 (ro) 1994-12-30
AU5829490A (en) 1991-01-07
JP2999820B2 (ja) 2000-01-17
KR920700032A (ko) 1992-02-19
CN1049101A (zh) 1991-02-13
ES2062366T3 (es) 1994-12-16
HU207795B (en) 1993-06-28
PL164128B1 (pl) 1994-06-30
EP0404376A3 (en) 1991-06-05
PL285507A1 (en) 1992-01-13
KR0169487B1 (ko) 1999-01-15

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