PH30454A - 1,2,4-Oxadiazolyl-phenoxy-alkyl-isoxazoles and their use as antiviral agents - Google Patents

1,2,4-Oxadiazolyl-phenoxy-alkyl-isoxazoles and their use as antiviral agents

Info

Publication number
PH30454A
PH30454A PH46044A PH46044A PH30454A PH 30454 A PH30454 A PH 30454A PH 46044 A PH46044 A PH 46044A PH 46044 A PH46044 A PH 46044A PH 30454 A PH30454 A PH 30454A
Authority
PH
Philippines
Prior art keywords
alkyl
alkoxy
antiviral agents
isoxazoles
oxadiazolyl
Prior art date
Application number
PH46044A
Other languages
English (en)
Inventor
Diana Guy Dominic
Theodore John Nitz
Original Assignee
Sterling Winthrop Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Winthrop Inc filed Critical Sterling Winthrop Inc
Publication of PH30454A publication Critical patent/PH30454A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PH46044A 1992-04-15 1993-04-14 1,2,4-Oxadiazolyl-phenoxy-alkyl-isoxazoles and their use as antiviral agents PH30454A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/869,287 US5349068A (en) 1992-04-15 1992-04-15 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents

Publications (1)

Publication Number Publication Date
PH30454A true PH30454A (en) 1997-05-28

Family

ID=25353269

Family Applications (1)

Application Number Title Priority Date Filing Date
PH46044A PH30454A (en) 1992-04-15 1993-04-14 1,2,4-Oxadiazolyl-phenoxy-alkyl-isoxazoles and their use as antiviral agents

Country Status (26)

Country Link
US (3) US5349068A (hu)
EP (1) EP0566199B1 (hu)
JP (1) JP3103845B2 (hu)
KR (1) KR100314158B1 (hu)
AT (1) ATE189958T1 (hu)
AU (1) AU666528B2 (hu)
CA (1) CA2094012C (hu)
CZ (1) CZ285845B6 (hu)
DE (1) DE69327913T2 (hu)
DK (1) DK0566199T3 (hu)
ES (1) ES2143487T3 (hu)
FI (1) FI112229B (hu)
GR (1) GR3033486T3 (hu)
HU (2) HU220606B1 (hu)
IL (1) IL105372A (hu)
MX (1) MX9302169A (hu)
MY (1) MY110191A (hu)
NO (1) NO302700B1 (hu)
NZ (1) NZ247411A (hu)
PH (1) PH30454A (hu)
PT (1) PT566199E (hu)
RU (1) RU2114112C1 (hu)
SG (1) SG50663A1 (hu)
SK (1) SK279786B6 (hu)
TW (1) TW239140B (hu)
UA (1) UA35557C2 (hu)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5349068A (en) * 1992-04-15 1994-09-20 Sterling Winthrop Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5552420A (en) * 1994-05-13 1996-09-03 Sterling Winthrop Inc. Therapeutic phenoxyalkylazoles and phenoxyalkylazines
IL118657A0 (en) * 1996-06-14 1996-10-16 Arad Dorit Inhibitors for picornavirus proteases
IL122591A0 (en) 1997-12-14 1998-06-15 Arad Dorit Pharmaceutical compositions comprising cystein protease inhibitors
US6348324B1 (en) 1999-01-21 2002-02-19 Hypoguard America Limited Composition and device for detecting leukocytes in urine
US6528652B1 (en) 1999-01-21 2003-03-04 Chronimed Composition and device for detecting leukocytes in urine
AUPQ105499A0 (en) 1999-06-18 1999-07-08 Biota Scientific Management Pty Ltd Antiviral agents
AUPR213700A0 (en) * 2000-12-18 2001-01-25 Biota Scientific Management Pty Ltd Antiviral agents
CN1638776A (zh) * 2001-06-08 2005-07-13 西托维亚公司 取代的3－芳基－5－芳基－[1,2,4]－噁二唑和类似物
US7129359B2 (en) * 2002-07-09 2006-10-31 National Health Research Institutes Imidazolidinone compounds
WO2003020271A1 (en) * 2001-08-29 2003-03-13 Viropharma Incorporated Oxadiazolyl-phenoxyalkylisoxazoles, compositions thereof and methods for their use as anti-picornaviral agents
US20050027127A1 (en) * 2001-08-29 2005-02-03 Diana Guy D. Oxadiazolyl-phenoxyalkylisoxazoles compositions thereof and methods for their use as anti-picornaviral agents
ES2345244T3 (es) 2001-12-07 2010-09-20 Ana Maria Sandino Composiciones para incrementar la supervivencia de animales acuaticos expuestos a virus rna.
US20060167109A1 (en) * 2002-02-14 2006-07-27 Pevear Daniel C Methods of reducing rhinovirus contagion and related compositions
US7144876B2 (en) * 2002-12-18 2006-12-05 Cytovia, Inc. 3,5-Disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof
US7259174B2 (en) * 2004-05-25 2007-08-21 National Health Research Institutes Imidazolidinone compounds
CA2575932A1 (en) * 2004-08-04 2006-02-16 Schering Corporation Pharmaceutical formulations comprising pleconaril for the treatment of airway diseases
WO2007095041A2 (en) * 2006-02-09 2007-08-23 Schering Corporation Pharmaceutical formulations
US20070203104A1 (en) * 2006-02-09 2007-08-30 Chaudhry Saeed M Pharmaceutical Formulations
CA2641605A1 (en) * 2006-02-09 2007-08-23 Schering Corporation Pharmaceutical formulations
RU2469032C2 (ru) 2006-12-13 2012-12-10 Ф.Хоффманн-Ля Рош Аг Производные 2-(пиперидин-4-ил)-4-фенокси- или фениламинопиримидина в качестве ненуклеозидных ингибиторов обратной транскриптазы
KR101031584B1 (ko) * 2009-04-21 2011-04-27 파인오토시스템(주) 전면부가 개폐되는 차량용 적외선 조사장치
CN103102322B (zh) * 2011-11-14 2016-02-24 上海交通大学 噁唑类化合物及其制备方法、药物组合物及其用途
CN112752761B (zh) 2018-08-21 2024-03-29 杏林制药株式会社 双环杂芳族环衍生物
US20230218644A1 (en) 2020-04-16 2023-07-13 Som Innovation Biotech, S.A. Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861791A (en) * 1983-08-29 1989-08-29 Sterling Drug Inc. Dihydro-oxazolyl substituted-phenyl-aliphatic lower alkyl and their use as antiviral agents
ZA846525B (en) * 1983-08-29 1985-04-24 Sterling Drug Inc (substituted)phenyl-aliphatic-isoxazoles useful as antiviral agents and preparation thereof
US4843087A (en) * 1983-08-29 1989-06-27 Sterling Drug Inc. Di-heterocyclic compounds and their use as antiviral agents
CA1280753C (en) * 1985-07-02 1991-02-26 Philip Michael Carabateas Process for preparing heterocyclic substituted- phenoxyalkyl isoxazoles and-furans
US4945164A (en) * 1989-08-18 1990-07-31 Sterling Drug Inc. 1,3,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents and intermediates thereof
US4942241A (en) * 1989-08-21 1990-07-17 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5175178A (en) * 1989-08-21 1992-12-29 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
NZ234760A (en) * 1989-08-18 1991-09-25 Sterling Drug Inc Antiviral oxazole compounds and compositions
US5175177A (en) * 1991-07-17 1992-12-29 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5349068A (en) * 1992-04-15 1994-09-20 Sterling Winthrop Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents

Also Published As

Publication number Publication date
SK35393A3 (en) 1994-06-08
HU220606B1 (hu) 2002-03-28
NO302700B1 (no) 1998-04-14
SK279786B6 (sk) 1999-03-12
EP0566199B1 (en) 2000-03-01
AU666528B2 (en) 1996-02-15
JP3103845B2 (ja) 2000-10-30
FI112229B (fi) 2003-11-14
DE69327913T2 (de) 2000-10-12
KR100314158B1 (ko) 2002-02-19
EP0566199A1 (en) 1993-10-20
HU211320A9 (en) 1995-11-28
PT566199E (pt) 2000-09-29
ATE189958T1 (de) 2000-03-15
US5643929A (en) 1997-07-01
MX9302169A (es) 1993-10-01
HU9301084D0 (en) 1993-06-28
HUT65574A (en) 1994-07-28
FI931707A (fi) 1993-10-16
KR930021637A (ko) 1993-11-22
IL105372A (en) 1998-12-27
SG50663A1 (en) 1998-07-20
UA35557C2 (uk) 2001-04-16
TW239140B (hu) 1995-01-21
RU2114112C1 (ru) 1998-06-27
ES2143487T3 (es) 2000-05-16
DK0566199T3 (da) 2000-06-19
US5349068A (en) 1994-09-20
CZ59793A3 (en) 1994-02-16
MY110191A (en) 1998-02-28
US5464848A (en) 1995-11-07
GR3033486T3 (en) 2000-09-29
NO931366D0 (no) 1993-04-14
CZ285845B6 (cs) 1999-11-17
NO931366L (no) 1993-10-18
AU3688193A (en) 1993-10-21
JPH0649066A (ja) 1994-02-22
IL105372A0 (en) 1993-08-18
CA2094012C (en) 2001-08-21
NZ247411A (en) 1994-06-27
FI931707A0 (fi) 1993-04-15
CA2094012A1 (en) 1993-10-16
DE69327913D1 (de) 2000-04-06

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