PH30436A - Tetrahydro-imidazolylmethyl carbazolones and analogs thereof for treating 5-ht function disturbances - Google Patents

Tetrahydro-imidazolylmethyl carbazolones and analogs thereof for treating 5-ht function disturbances

Info

Publication number
PH30436A
PH30436A PH36132A PH36132A PH30436A PH 30436 A PH30436 A PH 30436A PH 36132 A PH36132 A PH 36132A PH 36132 A PH36132 A PH 36132A PH 30436 A PH30436 A PH 30436A
Authority
PH
Philippines
Prior art keywords
carbazolones
imidazolylmethyl
tetrahydro
analogs
treating
Prior art date
Application number
PH36132A
Other languages
English (en)
Inventor
Ian Harold Coates
John Bradshaw
James Angus Bell
David Cedric Humber
George Blanch Ewan
William Leonard Mitchell
Original Assignee
Glaxo Groups Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868628473A external-priority patent/GB8628473D0/en
Priority claimed from GB878726537A external-priority patent/GB8726537D0/en
Application filed by Glaxo Groups Ltd filed Critical Glaxo Groups Ltd
Publication of PH30436A publication Critical patent/PH30436A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PH36132A 1986-11-28 1987-11-27 Tetrahydro-imidazolylmethyl carbazolones and analogs thereof for treating 5-ht function disturbances PH30436A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868628473A GB8628473D0 (en) 1986-11-28 1986-11-28 Chemical compounds
GB878726537A GB8726537D0 (en) 1987-11-12 1987-11-12 Tricyclic ketones

Publications (1)

Publication Number Publication Date
PH30436A true PH30436A (en) 1997-05-09

Family

ID=26291603

Family Applications (1)

Application Number Title Priority Date Filing Date
PH36132A PH30436A (en) 1986-11-28 1987-11-27 Tetrahydro-imidazolylmethyl carbazolones and analogs thereof for treating 5-ht function disturbances

Country Status (24)

Country Link
US (1) US4822881A (cs)
AT (1) AT396933B (cs)
AU (1) AU605805B2 (cs)
BE (1) BE1001004A4 (cs)
CA (1) CA1326032C (cs)
CH (1) CH676120A5 (cs)
CZ (1) CZ404591A3 (cs)
DE (1) DE3740352A1 (cs)
DK (1) DK169675B1 (cs)
ES (1) ES2008360A6 (cs)
FI (1) FI92062C (cs)
FR (1) FR2611366B1 (cs)
GB (1) GB2202530B (cs)
GR (1) GR871809B (cs)
HK (1) HK51591A (cs)
IE (1) IE61510B1 (cs)
IL (1) IL84635A (cs)
IT (1) IT1211936B (cs)
NL (1) NL8702851A (cs)
NO (1) NO172581C (cs)
NZ (1) NZ222725A (cs)
PH (1) PH30436A (cs)
SE (1) SE467255B (cs)
SG (1) SG46591G (cs)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8518742D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Process
US5202343A (en) * 1986-11-28 1993-04-13 Glaxo Group Limited Tricyclic ketones useful as HT3 -receptor antagonists
GB8812002D0 (en) * 1988-05-20 1988-06-22 Glaxo Group Ltd Chemical compounds
DE3822792C2 (de) * 1987-07-11 1997-11-27 Sandoz Ag Neue Verwendung von 5HT¶3¶-Antagonisten
GB8720693D0 (en) * 1987-09-03 1987-10-07 Glaxo Group Ltd Chemical compounds
US5360800A (en) * 1987-09-03 1994-11-01 Glaxo Group Limited Tetrahydro-1H-pyrido[4,3-b]indol-1-one derivatives
JPH01258673A (ja) * 1987-10-22 1989-10-16 Glaxo Group Ltd ケトン誘導体
JPH0249772A (ja) * 1988-04-07 1990-02-20 Glaxo Group Ltd イミダゾール誘導体
DK185489A (da) * 1988-04-22 1989-10-23 Duphar Int Res Imidazolylmethyl-cycloalkanoebaaindoloner, deres fremstilling og anvendelse
JPH0256485A (ja) * 1988-04-27 1990-02-26 Glaxo Group Ltd ラクタム誘導体
GB8812636D0 (en) * 1988-05-27 1988-06-29 Glaxo Group Ltd Chemical compounds
US5049563A (en) * 1988-07-07 1991-09-17 Duphar International Research B.V. Annelated indoleketones with an imidazolylalkyl substituent
CA1336906C (en) * 1988-08-02 1995-09-05 Peter Charles North Lactam derivatives
HU207078B (en) * 1988-08-02 1993-03-01 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising such compounds
US5008272A (en) * 1988-08-15 1991-04-16 Glaxo Group Limited Lactam derivatives
GB8820650D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
GB8820651D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
US4997831A (en) * 1988-09-01 1991-03-05 Glaxo Group Limited Lactam derivatives
GB8820653D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
AU627221B2 (en) * 1988-09-27 1992-08-20 Fujisawa Pharmaceutical Co., Ltd. Pyridoindole derivatives and processes for preparation thereof
GB8823980D0 (en) * 1988-10-13 1988-11-23 Glaxo Group Ltd Chemical compounds
US5223625A (en) * 1988-12-22 1993-06-29 Duphar International Research B.V. Annelated indolo [3,2,-C]lactams
GB8904551D0 (en) * 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical compounds
HU204049B (en) * 1989-02-28 1991-11-28 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising same
GB8904552D0 (en) 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical process
DE69004924T2 (de) 1989-04-21 1994-05-19 Sandoz Ag Therapeutische verwendung von 5-ht3-rezeptor-antagonisten.
GB8928208D0 (en) * 1989-12-13 1990-02-14 Glaxo Group Ltd Medicaments
HU211081B (en) * 1990-12-18 1995-10-30 Sandoz Ag Process for producing indole derivatives as serotonin antagonists and pharmaceutical compositions containing the same
KR100368895B1 (ko) * 2000-03-30 2003-01-24 하나제약 주식회사 1,2,3,9-테트라하이드로-9-메틸-3-[(2-메틸-1ｈ-이미다졸-1-일)메틸]-4ｈ-카바졸-4-온의 제조방법
CA2473392A1 (en) 2002-01-18 2003-07-31 Aryx Therapeutics 5-ht3 receptor antagonists and methods of use
KR101779991B1 (ko) 2009-05-20 2017-09-19 인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) 병소성 전정 질환을 치료하기 위한 세로토닌 5-ｈｔ3 수용체 길항제의 용도
ES2432618T3 (es) 2009-05-20 2013-12-04 Inserm (Institut National De La Santé Et De La Recherche Medicale) Antagonistas del receptor 5-HT3 de serotonina para usar en el tratamiento o prevención de una patología del oído interno con déficit vestibular

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3740404A (en) * 1969-05-09 1973-06-19 American Cyanamid Co Piperidinomethylenedihydrocarbazolones
US3634420A (en) * 1969-05-09 1972-01-11 American Cyanamid Co 3(morpholinomethyl)-2 3-dihydro-carbazol-4(1h)-ones
GB1365296A (en) * 1970-10-30 1974-08-29 Unilever Ltd Dentifrice compositions
US4176230A (en) * 1977-08-04 1979-11-27 Hoffmann-La Roche Inc. 5-(6-Alkylindol-3-ylmethylene)-1,3-dimethyl-2-(methylimino)-4-imidazolidinones
EP0051321B1 (en) * 1978-11-01 1986-03-26 The Wellcome Foundation Limited Cis-dimethylpiperazines for the preparation of n-substituted carbazoles
DK151884C (da) * 1979-03-07 1988-06-13 Pfizer Analogifremgangsmaade til fremstilling af 3-(1-imidazolylalkyl)indolderivater eller farmaceutisk acceptable syreadditionssalte deraf
HU193592B (en) * 1984-01-25 1987-11-30 Glaxo Group Ltd Process for producing tetrahydro-carbazolone derivatives
US4695578A (en) * 1984-01-25 1987-09-22 Glaxo Group Limited 1,2,3,9-tetrahydro-3-imidazol-1-ylmethyl-4H-carbazol-4-ones, composition containing them, and method of using them to treat neuronal 5HT function disturbances
EP0191562B1 (en) * 1985-01-23 1991-07-10 Glaxo Group Limited Tetrahydrocarbazolone derivatives
GB8518745D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Heterocyclic compounds
GB8518743D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Heterocyclic compounds
GB8518741D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Process

Also Published As

Publication number Publication date
FR2611366B1 (fr) 1990-03-16
FI92062B (fi) 1994-06-15
GR871809B (en) 1988-03-07
CH676120A5 (cs) 1990-12-14
AU605805B2 (en) 1991-01-24
NO172581C (no) 1993-08-11
IE873232L (en) 1988-05-28
ES2008360A6 (es) 1989-07-16
IL84635A (en) 1993-01-31
IT1211936B (it) 1989-11-08
US4822881A (en) 1989-04-18
SG46591G (en) 1991-07-26
SE8704746L (sv) 1988-05-29
SE8704746D0 (sv) 1987-11-27
CZ404591A3 (en) 1993-08-11
NO874959L (no) 1988-05-30
HK51591A (en) 1991-07-12
DE3740352A1 (de) 1988-06-09
DK624887D0 (da) 1987-11-27
IE61510B1 (en) 1994-11-16
ATA312487A (de) 1993-05-15
GB2202530A (en) 1988-09-28
CA1326032C (en) 1994-01-11
GB8727835D0 (en) 1987-12-31
NO172581B (no) 1993-05-03
AU8184587A (en) 1988-06-02
SE467255B (sv) 1992-06-22
NL8702851A (nl) 1988-06-16
FR2611366A1 (fr) 1988-09-02
FI875235A0 (fi) 1987-11-27
DK169675B1 (da) 1995-01-09
FI875235A7 (fi) 1988-05-29
NZ222725A (en) 1990-08-28
FI92062C (fi) 1994-09-26
NO874959D0 (no) 1987-11-27
IT8748642A0 (it) 1987-11-27
AT396933B (de) 1993-12-27
BE1001004A4 (fr) 1989-06-06
IL84635A0 (en) 1988-04-29
GB2202530B (en) 1990-04-18
DK624887A (da) 1988-05-29

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