PH25502A - - Google Patents
Info
- Publication number
- PH25502A PH25502A PH35961A PH35961A PH25502A PH 25502 A PH25502 A PH 25502A PH 35961 A PH35961 A PH 35961A PH 35961 A PH35961 A PH 35961A PH 25502 A PH25502 A PH 25502A
- Authority
- PH
- Philippines
- Prior art keywords
- cyclization
- excipient
- stabilizer
- lubricant
- hydrolysis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Lubricants (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/921,931 US4793998A (en) | 1986-10-20 | 1986-10-20 | Stabilized drug compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
PH25502A true PH25502A (ko) | 1991-07-24 |
Family
ID=25446206
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PH35961A PH25502A (ko) | 1986-10-20 | 1987-10-20 |
Country Status (19)
Country | Link |
---|---|
US (1) | US4793998A (ko) |
EP (1) | EP0264888B1 (ko) |
JP (1) | JP2852043B2 (ko) |
KR (1) | KR960000431B1 (ko) |
AT (1) | ATE65915T1 (ko) |
AU (1) | AU614710B2 (ko) |
CA (1) | CA1297023C (ko) |
DE (1) | DE3772001D1 (ko) |
DK (1) | DK174976B1 (ko) |
ES (1) | ES2040231T3 (ko) |
FI (1) | FI94092C (ko) |
GR (1) | GR3002454T3 (ko) |
HK (1) | HK85394A (ko) |
IE (1) | IE61436B1 (ko) |
NO (1) | NO174765C (ko) |
PH (1) | PH25502A (ko) |
PT (1) | PT85941B (ko) |
SG (1) | SG90194G (ko) |
ZA (1) | ZA877131B (ko) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1322957C (en) * | 1988-03-30 | 1993-10-12 | Hitoshi Yamauchi | Cyclic amp derivative ointments |
US5006344A (en) * | 1989-07-10 | 1991-04-09 | E. R. Squibb & Sons, Inc. | Fosinopril tablet formulations |
CA2019324C (en) * | 1989-07-10 | 1996-08-20 | Robert L. Jerzewski | Fosinopril tablet formulations |
EP0476156B1 (en) * | 1990-04-06 | 1996-08-07 | Eisai Co., Ltd. | Solid oral preparation containing catechol compound |
US6300361B1 (en) | 1990-07-25 | 2001-10-09 | Novartis Ag | Stabilized pharmaceutical compositions comprising acid donors |
HU222489B1 (hu) * | 1990-07-25 | 2003-07-28 | Novartis Ag. | Stabilizált gyógyszerkészítmények és eljárás az előállításukra |
HU222497B1 (hu) * | 1996-12-18 | 2003-07-28 | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. | Enalapril-maleátot tartalmazó stabilizált gyógyszerkészítmény és eljárás előállítására |
US6296871B1 (en) * | 1998-04-12 | 2001-10-02 | Ranbaxy Laboratories Limited | Stable solid pharmaceutical compositions containing enalapril maleate |
NZ508544A (en) | 1998-06-05 | 2002-10-25 | Warner Lambert Co | Angiotensin converting enzyme inhibitors, such as quinapril, enalapril and indolapril, stabilised with 1-90 wt% magnesium oxide |
US20030225124A1 (en) * | 1999-08-31 | 2003-12-04 | Spiridon Spireas | Stable formulations of ACE inhibitors, and methods for preparation thereof |
US6555551B1 (en) | 1999-08-31 | 2003-04-29 | Mutual Pharmaceutical Co., Inc. | Stable formulations of ACE inhibitors, and methods for preparation thereof |
US20040157911A1 (en) * | 1999-08-31 | 2004-08-12 | Spiridon Spireas | Storage-stable and bio-stable formulations of ace inhibitors, and methods for preparation thereof |
AU7580000A (en) * | 1999-09-17 | 2001-04-17 | Mylan Pharmaceuticals, Inc. | Stabilization of enalapril maleate with maleic acid |
CA2469940A1 (en) * | 2001-12-19 | 2003-06-26 | Takeda Chemical Industries, Ltd. | Solid compositions comprising compounds unstable to oxygen and method for stabilizing them |
EP1467717A1 (en) * | 2002-01-15 | 2004-10-20 | Ranbaxy Laboratories Limited | Stable pharmaceutical compositions comprising ace inhibitor(s) |
PL1635792T3 (pl) * | 2003-06-26 | 2009-08-31 | Teva Pharmaceutical Industries Ltd | Stabilne kompozycje farmaceutyczne pochodnych kwasu 2-aza-bicyklo[3.3.0]-oktano-3-karboksylowego |
US6869963B2 (en) * | 2003-07-11 | 2005-03-22 | Sandoz Ag | Stable pharmaceutical compositions containing an ACE inhibitor |
GR1006875B (el) * | 2005-06-30 | 2010-07-12 | "Φαρματεν" Φαρμακευτικη Βιομηχανικη Εμπορικη Α.Ε., | Βελτιωμενες φαρμακευτικες συνθεσεις περιεχουσες αναστολεις του μετατρεπτικου ενζυμου αγγειοτενσινης και μεθοδοι παρασκευης αυτων. |
EP1815857A1 (en) | 2006-02-02 | 2007-08-08 | LEK Pharmaceuticals D.D. | A pharmaceutical composition comprising perindopril |
US20070232680A1 (en) * | 2006-04-04 | 2007-10-04 | Vijayabhaskar Bolugoddu | Preparation of ramipril and stable pharmaceutical compositions |
RU2008145115A (ru) * | 2006-04-19 | 2010-05-27 | Тева Фармасьютикл Индастриес Лтд. (Il) | Стабильные фармацевтические композиции производственных соединений 2-аза-бицикло[3.3.0]-октан-3-карбоновой кислоты |
US20080008694A1 (en) | 2006-07-05 | 2008-01-10 | Elgebaly Salwa A | Methods to prevent and treat diseases |
ES2364011B1 (es) | 2009-11-20 | 2013-01-24 | Gp Pharm, S.A. | Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados para el tratamiento de enfermedades cardiovasculares. |
US8568747B1 (en) | 2012-10-05 | 2013-10-29 | Silvergate Pharmaceuticals, Inc. | Enalapril compositions |
US9463183B1 (en) | 2015-10-30 | 2016-10-11 | Silvergate Pharmaceuticals, Inc. | Lisinopril formulations |
US9669008B1 (en) | 2016-03-18 | 2017-06-06 | Silvergate Pharmaceuticals, Inc. | Enalapril formulations |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE569430A (ko) * | 1957-07-17 | |||
US3697641A (en) * | 1970-01-02 | 1972-10-10 | Gerhard W Ahrens | Nonhygroscopic non-sugarbase noncariogenic-vitamin c releasable base material for use in the preparation of suckable tablets,lozenges and chocolate |
EP0045238B1 (en) * | 1980-07-29 | 1986-10-01 | Sanofi S.A. | Acid stabilized compositions of thieno-pyridine derived compounds and process for preventing degradation of such compounds |
US4344949A (en) * | 1980-10-03 | 1982-08-17 | Warner-Lambert Company | Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids |
US4442089A (en) * | 1982-07-06 | 1984-04-10 | E. R. Squibb & Sons, Inc. | Method for treating glaucoma with topical or systemic ACE inhibitor compositions |
US4499079A (en) * | 1982-11-18 | 1985-02-12 | E. R. Squibb & Sons, Inc. | Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides |
US4666705A (en) * | 1985-06-03 | 1987-05-19 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
US4656188A (en) * | 1985-10-09 | 1987-04-07 | Merck & Co., Inc. | Ace inhibitors in macular degeneration |
-
1986
- 1986-10-20 US US06/921,931 patent/US4793998A/en not_active Expired - Lifetime
-
1987
- 1987-09-18 CA CA000547230A patent/CA1297023C/en not_active Expired - Lifetime
- 1987-09-22 IE IE254987A patent/IE61436B1/en not_active IP Right Cessation
- 1987-09-22 ZA ZA877131A patent/ZA877131B/xx unknown
- 1987-10-01 AU AU79274/87A patent/AU614710B2/en not_active Expired
- 1987-10-16 DK DK198705436A patent/DK174976B1/da not_active IP Right Cessation
- 1987-10-19 AT AT87115282T patent/ATE65915T1/de not_active IP Right Cessation
- 1987-10-19 PT PT85941A patent/PT85941B/pt unknown
- 1987-10-19 ES ES198787115282T patent/ES2040231T3/es not_active Expired - Lifetime
- 1987-10-19 DE DE8787115282T patent/DE3772001D1/de not_active Expired - Lifetime
- 1987-10-19 JP JP62261930A patent/JP2852043B2/ja not_active Expired - Lifetime
- 1987-10-19 EP EP87115282A patent/EP0264888B1/en not_active Expired - Lifetime
- 1987-10-19 FI FI874593A patent/FI94092C/fi not_active IP Right Cessation
- 1987-10-19 NO NO874351A patent/NO174765C/no not_active IP Right Cessation
- 1987-10-20 KR KR1019870011655A patent/KR960000431B1/ko not_active IP Right Cessation
- 1987-10-20 PH PH35961A patent/PH25502A/en unknown
-
1991
- 1991-08-08 GR GR91401122T patent/GR3002454T3/el unknown
-
1994
- 1994-07-07 SG SG90194A patent/SG90194G/en unknown
- 1994-08-18 HK HK85394A patent/HK85394A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NO874351D0 (no) | 1987-10-19 |
NO174765B (no) | 1994-03-28 |
IE872549L (en) | 1988-04-20 |
US4793998A (en) | 1988-12-27 |
JP2852043B2 (ja) | 1999-01-27 |
NO874351L (no) | 1988-04-21 |
DK543687A (da) | 1988-04-21 |
HK85394A (en) | 1994-08-26 |
DK174976B1 (da) | 2004-04-05 |
KR880004812A (ko) | 1988-06-27 |
FI94092C (fi) | 1995-07-25 |
PT85941A (en) | 1987-11-01 |
FI874593A0 (fi) | 1987-10-19 |
AU614710B2 (en) | 1991-09-05 |
CA1297023C (en) | 1992-03-10 |
ZA877131B (en) | 1989-04-26 |
IE61436B1 (en) | 1994-11-02 |
ES2040231T3 (es) | 1993-10-16 |
DE3772001D1 (de) | 1991-09-12 |
EP0264888B1 (en) | 1991-08-07 |
ATE65915T1 (de) | 1991-08-15 |
FI874593A (fi) | 1988-04-21 |
SG90194G (en) | 1994-10-14 |
FI94092B (fi) | 1995-04-13 |
GR3002454T3 (en) | 1992-12-30 |
PT85941B (pt) | 1990-07-31 |
DK543687D0 (da) | 1987-10-16 |
JPS63104930A (ja) | 1988-05-10 |
AU7927487A (en) | 1988-04-28 |
KR960000431B1 (ko) | 1996-01-06 |
EP0264888A1 (en) | 1988-04-27 |
NO174765C (no) | 1994-07-06 |
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