AU7580000A - Stabilization of enalapril maleate with maleic acid - Google Patents

Stabilization of enalapril maleate with maleic acid

Info

Publication number
AU7580000A
AU7580000A AU75800/00A AU7580000A AU7580000A AU 7580000 A AU7580000 A AU 7580000A AU 75800/00 A AU75800/00 A AU 75800/00A AU 7580000 A AU7580000 A AU 7580000A AU 7580000 A AU7580000 A AU 7580000A
Authority
AU
Australia
Prior art keywords
stabilization
maleic acid
enalapril maleate
enalapril
maleate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU75800/00A
Inventor
William J. Addicks
Pavan Bhat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mylan Pharmaceuticals Inc
Original Assignee
Mylan Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mylan Pharmaceuticals Inc filed Critical Mylan Pharmaceuticals Inc
Publication of AU7580000A publication Critical patent/AU7580000A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU75800/00A 1999-09-17 2000-09-15 Stabilization of enalapril maleate with maleic acid Abandoned AU7580000A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39749899A 1999-09-17 1999-09-17
US09397498 1999-09-17
PCT/US2000/025184 WO2001019348A1 (en) 1999-09-17 2000-09-15 Stabilization of enalapril maleate with maleic acid

Publications (1)

Publication Number Publication Date
AU7580000A true AU7580000A (en) 2001-04-17

Family

ID=23571441

Family Applications (1)

Application Number Title Priority Date Filing Date
AU75800/00A Abandoned AU7580000A (en) 1999-09-17 2000-09-15 Stabilization of enalapril maleate with maleic acid

Country Status (2)

Country Link
AU (1) AU7580000A (en)
WO (1) WO2001019348A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2824477B1 (en) * 2001-05-09 2005-09-09 Ethypharm Lab Prod Ethiques ENVELOPED GRANULES BASED ON INHIBITOR OF THE ANFIOTENSIN CONVERTING ENZYME, PROCESS FOR THEIR PREPARATION AND ORODISPERSIBLE TABLETS CONTAINING COATED GRANULES
US7879382B2 (en) 2005-09-30 2011-02-01 Fmc Corporation Stabilizers and compositions and products comprising same
WO2008057267A2 (en) 2006-10-27 2008-05-15 Fmc Corporation Co-processed microcrystalline cellulose and sugar alcohol as an excipient for tablet formulations
WO2012085249A2 (en) 2010-12-24 2012-06-28 Krka, D.D., Novo Mesto Homogenous pharmaceutical oral dosage forms comprising lercanidipine and enalapril or their pharmaceutically acceptable salts
BR112014007880B1 (en) 2011-10-05 2020-07-14 Dupont Nutrition Usa, Inc STABILIZING COMPOSITION OF CO-ATRITTED MICROCRYSTALLINE CELLULOSE AND CARBOXIMETHYLCELLULOSE, PREPARATION METHOD, AND USES
US9826763B2 (en) 2011-10-05 2017-11-28 Fmc Corporation Stabilizer composition of microcrystalline cellulose and carboxymethylcellulose, method for making, and uses
CN104010522A (en) 2011-12-09 2014-08-27 Fmc有限公司 Co-attrited stabilizer composition
CN107007838B (en) * 2016-09-30 2021-07-20 南京优科制药有限公司 A pharmaceutical composition containing enalapril maleate, folic acid and acid stabilizer
CN106822859A (en) * 2017-03-31 2017-06-13 华益药业科技(安徽)有限公司 A kind of enalapril maleate piece and preparation method thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4793998A (en) * 1986-10-20 1988-12-27 Warner-Lambert Company Stabilized drug compositions
HU222497B1 (en) * 1996-12-18 2003-07-28 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Stabilized pharmaceutical composition containing enalapril maleate and process for producing it
MY121470A (en) * 1999-05-03 2006-01-28 Ranbaxy Lab Ltd Stable solid pharmaceutical compositions containing enalapril maleate

Also Published As

Publication number Publication date
WO2001019348A1 (en) 2001-03-22

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase