FI94092B - Menetelmä kinapriilin stabiloimiseksi - Google Patents

Menetelmä kinapriilin stabiloimiseksi

Info

Publication number
FI94092B
FI94092B FI874593A FI874593A FI94092B FI 94092 B FI94092 B FI 94092B FI 874593 A FI874593 A FI 874593A FI 874593 A FI874593 A FI 874593A FI 94092 B FI94092 B FI 94092B
Authority
FI
Finland
Prior art keywords
quinapril
stabilizing
cyclization
excipient
stabilizer
Prior art date
Application number
FI874593A
Other languages
English (en)
Swedish (sv)
Other versions
FI874593A (fi
FI874593A0 (fi
FI94092C (fi
Inventor
Kuchi Sury Murthy
Michael Ray Harris
Gerard Clifford Hokanson
Jr Robert George Reisch
Mahdi Bakir Fawzi
Frank Stanley Waldman
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25446206&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI94092(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of FI874593A0 publication Critical patent/FI874593A0/fi
Publication of FI874593A publication Critical patent/FI874593A/fi
Publication of FI94092B publication Critical patent/FI94092B/fi
Application granted granted Critical
Publication of FI94092C publication Critical patent/FI94092C/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Lubricants (AREA)
FI874593A 1986-10-20 1987-10-19 Menetelmä kinapriilin stabiloimiseksi FI94092C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/921,931 US4793998A (en) 1986-10-20 1986-10-20 Stabilized drug compositions
US92193186 1986-10-20

Publications (4)

Publication Number Publication Date
FI874593A0 FI874593A0 (fi) 1987-10-19
FI874593A FI874593A (fi) 1988-04-21
FI94092B true FI94092B (fi) 1995-04-13
FI94092C FI94092C (fi) 1995-07-25

Family

ID=25446206

Family Applications (1)

Application Number Title Priority Date Filing Date
FI874593A FI94092C (fi) 1986-10-20 1987-10-19 Menetelmä kinapriilin stabiloimiseksi

Country Status (19)

Country Link
US (1) US4793998A (fi)
EP (1) EP0264888B1 (fi)
JP (1) JP2852043B2 (fi)
KR (1) KR960000431B1 (fi)
AT (1) ATE65915T1 (fi)
AU (1) AU614710B2 (fi)
CA (1) CA1297023C (fi)
DE (1) DE3772001D1 (fi)
DK (1) DK174976B1 (fi)
ES (1) ES2040231T3 (fi)
FI (1) FI94092C (fi)
GR (1) GR3002454T3 (fi)
HK (1) HK85394A (fi)
IE (1) IE61436B1 (fi)
NO (1) NO174765C (fi)
PH (1) PH25502A (fi)
PT (1) PT85941B (fi)
SG (1) SG90194G (fi)
ZA (1) ZA877131B (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1322957C (en) * 1988-03-30 1993-10-12 Hitoshi Yamauchi Cyclic amp derivative ointments
US5006344A (en) * 1989-07-10 1991-04-09 E. R. Squibb & Sons, Inc. Fosinopril tablet formulations
CA2019324C (en) * 1989-07-10 1996-08-20 Robert L. Jerzewski Fosinopril tablet formulations
JP3210663B2 (ja) * 1990-04-06 2001-09-17 エーザイ株式会社 カテコール化合物を含有する経口用固形製剤
HU222489B1 (hu) * 1990-07-25 2003-07-28 Novartis Ag. Stabilizált gyógyszerkészítmények és eljárás az előállításukra
US6300362B1 (en) 1990-07-25 2001-10-09 Novartis Ag (Formerly Sandoz Ltd.) Stabilized pharmaceutical compositions comprising acid donors
HU222497B1 (hu) * 1996-12-18 2003-07-28 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Enalapril-maleátot tartalmazó stabilizált gyógyszerkészítmény és eljárás előállítására
US6296871B1 (en) * 1998-04-12 2001-10-02 Ranbaxy Laboratories Limited Stable solid pharmaceutical compositions containing enalapril maleate
BR9910947A (pt) * 1998-06-05 2001-03-06 Warner Lambert Co Estabilização de composições que contêm inibidores de ace utilizando óxido de magnésio
US20030225124A1 (en) * 1999-08-31 2003-12-04 Spiridon Spireas Stable formulations of ACE inhibitors, and methods for preparation thereof
US20040157911A1 (en) * 1999-08-31 2004-08-12 Spiridon Spireas Storage-stable and bio-stable formulations of ace inhibitors, and methods for preparation thereof
US6555551B1 (en) 1999-08-31 2003-04-29 Mutual Pharmaceutical Co., Inc. Stable formulations of ACE inhibitors, and methods for preparation thereof
AU7580000A (en) * 1999-09-17 2001-04-17 Mylan Pharmaceuticals, Inc. Stabilization of enalapril maleate with maleic acid
AU2002366313A1 (en) * 2001-12-19 2003-06-30 Takeda Chemical Industries, Ltd. Solid compositions containng compounds unstable to oxygen and method for stabilization thereof
BR0306928A (pt) * 2002-01-15 2004-11-09 Ranbaxy Lab Ltd Composições farmacêuticas estáveis compreendendo inibidores de enzimas conversoras de angiotensina (ace)
CA2530788C (en) * 2003-06-26 2010-02-09 Teva Pharmaceutical Industries Ltd Stable pharmaceutical compositions of 2-aza-bicyclo[3.3.0]-octane-3-carboxylic acid derivatives
US6869963B2 (en) * 2003-07-11 2005-03-22 Sandoz Ag Stable pharmaceutical compositions containing an ACE inhibitor
GR1006875B (el) * 2005-06-30 2010-07-12 "Φαρματεν" Φαρμακευτικη Βιομηχανικη Εμπορικη Α.Ε., Βελτιωμενες φαρμακευτικες συνθεσεις περιεχουσες αναστολεις του μετατρεπτικου ενζυμου αγγειοτενσινης και μεθοδοι παρασκευης αυτων.
EP1815857A1 (en) 2006-02-02 2007-08-08 LEK Pharmaceuticals D.D. A pharmaceutical composition comprising perindopril
US20070232680A1 (en) * 2006-04-04 2007-10-04 Vijayabhaskar Bolugoddu Preparation of ramipril and stable pharmaceutical compositions
JP2009533461A (ja) * 2006-04-19 2009-09-17 テバ ファーマシューティカル インダストリーズ リミティド ２−アザ−ビシクロ［３．３．０］−オクタン−３−カルボン酸誘導体の安定な医薬組成物
US20080008694A1 (en) * 2006-07-05 2008-01-10 Elgebaly Salwa A Methods to prevent and treat diseases
ES2364011B1 (es) 2009-11-20 2013-01-24 Gp Pharm, S.A. Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados para el tratamiento de enfermedades cardiovasculares.
US8568747B1 (en) 2012-10-05 2013-10-29 Silvergate Pharmaceuticals, Inc. Enalapril compositions
US9463183B1 (en) 2015-10-30 2016-10-11 Silvergate Pharmaceuticals, Inc. Lisinopril formulations
US9669008B1 (en) 2016-03-18 2017-06-06 Silvergate Pharmaceuticals, Inc. Enalapril formulations

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE569430A (fi) * 1957-07-17
US3697641A (en) * 1970-01-02 1972-10-10 Gerhard W Ahrens Nonhygroscopic non-sugarbase noncariogenic-vitamin c releasable base material for use in the preparation of suckable tablets,lozenges and chocolate
ATE22530T1 (de) * 1980-07-29 1986-10-15 Sanofi Sa Durch saeure stabilisierte mischungen von thienopyridinderivaten und verfahren zum verhindern der zersetzung solcher verbindungen.
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4442089A (en) * 1982-07-06 1984-04-10 E. R. Squibb & Sons, Inc. Method for treating glaucoma with topical or systemic ACE inhibitor compositions
US4499079A (en) * 1982-11-18 1985-02-12 E. R. Squibb & Sons, Inc. Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides
US4666705A (en) * 1985-06-03 1987-05-19 E. R. Squibb & Sons, Inc. Controlled release formulation
US4656188A (en) * 1985-10-09 1987-04-07 Merck & Co., Inc. Ace inhibitors in macular degeneration

Also Published As

Publication number Publication date
NO874351D0 (no) 1987-10-19
JP2852043B2 (ja) 1999-01-27
AU7927487A (en) 1988-04-28
NO874351L (no) 1988-04-21
ES2040231T3 (es) 1993-10-16
FI874593A (fi) 1988-04-21
US4793998A (en) 1988-12-27
HK85394A (en) 1994-08-26
KR880004812A (ko) 1988-06-27
DE3772001D1 (de) 1991-09-12
AU614710B2 (en) 1991-09-05
IE61436B1 (en) 1994-11-02
ATE65915T1 (de) 1991-08-15
PT85941A (en) 1987-11-01
NO174765C (no) 1994-07-06
IE872549L (en) 1988-04-20
FI874593A0 (fi) 1987-10-19
EP0264888A1 (en) 1988-04-27
PH25502A (fi) 1991-07-24
DK543687A (da) 1988-04-21
DK543687D0 (da) 1987-10-16
SG90194G (en) 1994-10-14
NO174765B (no) 1994-03-28
GR3002454T3 (en) 1992-12-30
FI94092C (fi) 1995-07-25
CA1297023C (en) 1992-03-10
KR960000431B1 (ko) 1996-01-06
PT85941B (pt) 1990-07-31
EP0264888B1 (en) 1991-08-07
ZA877131B (en) 1989-04-26
DK174976B1 (da) 2004-04-05
JPS63104930A (ja) 1988-05-10

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Legal Events

Date Code Title Description
BB Publication of examined application
FG Patent granted

Owner name: WARNER-LAMBERT COMPANY

MA Patent expired